Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection. by Mathias Franzén Boger, Tyra Hasselrot, Vilde Kaldhusdal, Gisele H B Miranda, Paulo Czarnewski, Gabriella Edfeldt, Frideborg Bradley, Genta Rexaj, Julie Lajoie, Kenneth Omollo, Joshua Kimani, Keith R Fowke, Kristina Broliden, Annelie Tjernlund

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Integrated analysis of microbiome and metabolome reveals signatures in PDAC tumorigenesis and prognosis by Yuan Fang, Xiaohong Liu, Jie Ren, Xing Wang, Feihan Zhou, Shi Huang, Lei You, Yupei Zhao

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HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2. by Karen E Ocwieja, Troy L Brady, Keshet Ronen, Alyssa Huegel, Shoshannah L Roth, Torsten Schaller, Leo C James, Greg J Towers, John A T Young, Sumit K Chanda, Renate König, Nirav Malani, Charles C Berry, Frederic D Bushman

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Exploring associations between metabolites and gene transcripts of common bean (Phaseolus vulgaris L.) in response to rust (Uromyces appendiculatus) infection by Penny Makhumbila, Molemi Rauwane, Hangwani Muedi, Ntakadzeni E. Madala, Sandiswa Figlan

“…Abstract Common bean (Phaseolus vulgaris L.) faces escalating challenges resulting from the increasing prevalence of fungal pathogens such as rust caused by Uromyces appendiculatus, threatening yields and quality of the crop. …”
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Molecularly imprinted polymers and metal-organic framework-based nanomaterial sensors for food and beverage analysis and safety–A review by Favour Ezinne Ogulewe, Akeem Adeyemi Oladipo, Mustafa Gazi

“…This review examines the integration of MIPs and MOFs in electrochemical and fluorescence sensors for food analysis, detailing sensing mechanisms, performance factors, and electrode coating advancements. …”
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The Proteolytic Activation, Toxic Effects, and Midgut Histopathology of the <i>Bacillus thuringiensis</i> Cry1Ia Protoxin in <i>Rhynchophorus ferrugineus</i> (Coleoptera: Curculion... by Camilo Ayra-Pardo, Victor Ramaré, Ana Couto, Mariana Almeida, Ricardo Martins, José Américo Sousa, Maria João Santos

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Nanoarchitectonics for Advancing Bone Graft Technology: Integration of Silver Nanoparticles Against Bacteria and Fungi by Leticia Ramos Dantas, Maria Alice Witt, Everdan Carneiro, Felipe Francisco Tuon

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Computational tools and data integration to accelerate vaccine development: challenges, opportunities, and future directions by Lindsey N. Anderson, Charles Tapley Hoyt, Jeremy D. Zucker, Andrew D. McNaughton, Jeremy R. Teuton, Klas Karis, Natasha N. Arokium-Christian, Jackson T. Warley, Zachary R. Stromberg, Benjamin M. Gyori, Benjamin M. Gyori, Neeraj Kumar

“…Significant gaps in data and knowledge integration can hinder vaccine development which relies on a comprehensive understanding of the interplay between pathogens and the host immune system. …”
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Novel Antischistosomal Drug Targets: Identification of Alkaloid Inhibitors of SmTGR via Integrated In Silico Methods by Valéria V. M. Paixão, Yria J. A. Santos, Adriana O. Fernandes, Elaine S. Conceição, Ricardo P. Rodrigues, Daniela A. Chagas-Paula, Silvio S. Dolabella, Tiago B. Oliveira

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Dual RNA-seq study of the dynamics of coding and non-coding RNA expression during Clostridioides difficile infection in a mouse model by Victor Kreis, Claire Toffano-Nioche, Cécile Denève-Larrazet, Jean-Christophe Marvaud, Julian R. Garneau, Florent Dumont, Erwin L. van Dijk, Yan Jaszczyszyn, Anaïs Boutserin, Francesca D'Angelo, Daniel Gautheret, Imad Kansau, Claire Janoir, Olga Soutourina

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The impact of environmental and host factors on wolbachia density and efficacy as a biological tool by John Roberts Padde, Qingyu Lu, Yuang Long, Donghui Zhang, Min Hou, Lu Chen, Zhipeng Xu, Lin Chen, Minjun Ji

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Recent advances on surface enhanced Raman spectroscopy in safety assessment and quality control of meat and meat products by Meihong Wu, Hui He

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Dual single-cell and bulk RNA sequencing reveal transcriptional profiles underlying heterogenous host-parasite interactions in human peripheral blood mononuclear cells by Praveena Chandrasegaran, Bekir Faydaci, Barbara Shih, Barbara Shih, Musa A. Hassan

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Defending rice crop from blast disease in the context of climate change for food security in Nepal by Ram Bahadur Khadka, Hira Kaji Manandhar, Sundar Shrestha, Basistha Acharya, Pratiksha Sharma, Suraj Baidya, Van Schepler Luu, Krishna Dev Joshi

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miR472 Deficiency Enhances Arabidopsis thaliana Defense Without Reducing Seed Production by Francois Vasseur, Patricia Baldrich, Tamara Jiménez-Góngora, Luis Villar-Martin, Detlef Weigel, Ignacio Rubio-Somoza

“…The potential evolutionary advantage of such regulation remains largely unknown and might be related to two nonexclusive scenarios: (i) miRNA-dependent regulation of NLR levels might prevent defense mis-activation with negative effects on plant growth and reproduction or (ii) reduction of active miRNA levels in response to pathogen-derived molecules (pathogen-associated molecular patterns [PAMPs] and silencing suppressors) might rapidly release otherwise silent NLR transcripts for rapid translation and thereby enhance defense. …”
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TIMP1 secretion induced by Toxoplasma effector GRA24 via p38 MAPK signaling promotes non-disruptive parasite translocation across polarized brain endothelial monolayers by Elena Afanaseva, Antonio Barragan

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Strategic Detection of <i>Escherichia coli</i> in the Poultry Industry: Food Safety Challenges, One Health Approaches, and Advances in Biosensor Technologies by Jacquline Risalvato, Alaa H. Sewid, Shigetoshi Eda, Richard W. Gerhold, Jie Jayne Wu

“…Emphasis is placed on field-deployable and point-of-care (POC) platforms capable of integrating into poultry production environments. In addition to enhancing early pathogen detection, biosensors support antimicrobial resistance monitoring, facilitate integration into Hazard Analysis Critical Control Points (HACCP) systems, and align with the One Health framework by improving both animal and public health outcomes. …”
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Saponins, the Unexplored Secondary Metabolites in Plant Defense: Opportunities in Integrated Pest Management by Adnan Shakeel, Jewel Jameeta Noor, Uzma Jan, Aabida Gul, Zafar Handoo, Nasheeman Ashraf

“…It also provides the first holistic review on the role of saponins with known mechanisms against all of the major plant pathogens/pests. Furthermore, this review discusses the potential of saponin-rich crops in providing eco-friendly pest/pathogen management products for integrated pest management (IPM) and prospectives on the potential of saponin derivatives in developing novel biocides for sustainable agriculture.…”
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A novel tool for stable genomic reporter gene integration to analyze heterogeneity in Photorhabdus luminescens at the single-cell level by Angela Glaeser, Ralf Heermann

“…Determination of reporter gene activity at the single-cell level is a prerequisite for analyzing heterogeneous gene expression in bacteria. The insect pathogenic enteric bacterium Photorhabdus luminescens is an excellent organism in which to study heterogeneity since it exists in two phenotypically different forms, called the primary and secondary variant. …”
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Interlinkages and indicators: novel assessment of water, sanitation and solid waste services in schools in two Ugandan towns by Charlotte Farine, Charlotte Farine, Christoph Lüthi, Charles Buregeya Niwagaba, Eberhard Morgenroth, Eberhard Morgenroth, Abishek Sankara Narayan

“…Only 46% have access to basic water services, 44% to basic sanitation services, and 26% to basic hygienic services. Although integrating these services with other water and waste streams could benefit service provision, a systematic methodology for such integration does not exist yet. …”
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