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Animal Wellness: The Power of Multiomics and Integrative Strategies
Published 2024-01-01“…Omics methods are routinely used to identify genes involved in host-pathogen interactions, assess fitness traits, and pinpoint animals with disease resistance. …”
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342
Target Selection, Homokaryotic Isolation, and Screening Methods for Gene Editing in the Destructive Global Pathogen, <i>Phytophthora cinnamomi</i>
Published 2025-02-01“…<i>Phytophthora cinnamomi</i> is a major plant pathogen that affects economically important crops and natural ecosystems, posing a threat to global biodiversity. …”
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343
Effect of processing methods and Ethiopian ginger (Zingiber officinale) genotypes on antimicrobial properties against food pathogens and spoilage microorganisms
Published 2025-12-01“…Further research is recommended to optimize extraction techniques and explore the integration of Ethiopian ginger extracts into food preservation systems to mitigate microbial spoilage.…”
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344
A novel post-mortem pathogen discovery program detects an outbreak of Echovirus E7: Uganda, 2022–2023
Published 2025-07-01“…An epidemiologic assessment indicated that most identified pathogens were acquired via direct and/or indirect contact (e.g., fecal-oral, fomites) and that other modes of transmission (e.g., food-borne, insect-vectored) played a less significant role.ConclusionIntegration of mortuary surveillance, coupled with mNGS, into public health systems represents a powerful strategy for identifying unrecognized outbreaks and monitoring the (re-) emergence of infectious diseases.…”
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HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration.
Published 2021-09-01Get full text
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MoMkt1, a member of XPG/RAD2 nuclease family, regulates development and pathogenicity in Magnaporthe oryzae
Published 2025-12-01“…Our study provides insights into MoMkt1-mediated development and pathogenicity in M. oryzae.…”
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Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni
Published 2025-03-01“…Our integrated approach combined with independent validation expanded the small proteome by two-fold, including CioY, a new 34 aa component of the CioAB oxidase. …”
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IL‐6 signaling regulates the inflammatory response without impacting pathogen burden during influenza‐associated pulmonary aspergillosis
Published 2025-05-01“…Abstract Viral infections increase host susceptibility to opportunistic pathogens like Aspergillus fumigatus (AF), exacerbating disease severity and prolonging its clinical course. …”
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BroadAMP-GPT: AI-Driven generation of broad-spectrum antimicrobial peptides for combating multidrug-resistant ESKAPE pathogens
Published 2025-12-01“…Using this platform, 57% of AI-generated candidates exhibited potent efficacy against ESKAPE pathogens – key culprits of multidrug-resistant infections. …”
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357
Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow
Published 2025-02-01“…Abstract This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. …”
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358
Effect of seed protectants on fungal disease pathogens when using different technologies of oilseed flax, Linum usitatissimum cultivation
Published 2023-10-01“…The study aimed to evaluate the effect of Seedspor W and Olymp SC protectants on the seed infection pathogens, Fusarium ssp. and Colletotrichum ssp. against the background of different technologies of flax cultivation. …”
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A RACK1 family protein regulates pathogenicity of Peronophythora litchii by acting as a scaffold for MAPK signal modules
Published 2025-12-01“…CRISPR/Cas9-mediated genome editing technology was used to knock out PlRACK1, and we found that it was involved in mycelial growth, cell wall integrity, ROS metabolism, laccase activity, and pathogenicity of P. litchii. …”
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Antibacterial and antibiofilm activity of peptide PvGBP2 against pathogenic bacteria that contaminate Auricularia auricular culture bags
Published 2022-11-01“…Thus, peptide PvGBP2 could be potentially applied as an antibacterial agent to control bacterial infection of A. auricular cultivation and the spread of foodborne pathogens.…”
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