Flavivirus and Filovirus EvoPrinters: New alignment tools for the comparative analysis of viral evolution. by Thomas Brody, Amarendra S Yavatkar, Dong Sun Park, Alexander Kuzin, Jermaine Ross, Ward F Odenwald

“…Multi-genome comparative analysis of these evolving pathogens affords a view of their essential, conserved sequence elements as well as progressive evolutionary changes. …”
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Applying machine learning with MobileNetV2 model for rapid screening of vaginal discharge samples in vaginitis diagnosis by Thi Bang-Suong Nguyen, Hoang-Bac Nguyen, Thi Xuan-Thao Le, Thi Hong-Chau Bui, Le Song-Toan Nguyen, Thao-Huong Nguyen, Truong Cong-Minh Nguyen

“…This model supports doctors in identifying causative agents of vaginitis, including Gardnerella vaginalis, fungi, and other pathogens like bacteria or Trichomonas vaginalis. A dataset of 3,164 images from 1,582 vaginal discharge samples of women aged 18 and over was analyzed. …”
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The Role of Next-Generation Sequencing (NGS) in the Relationship between the Intestinal Microbiome and Periprosthetic Joint Infections: A Perspective by Salvatore Gioitta Iachino, Federica Scaggiante, Claudia Mazzarisi, Christian Schaller

“…In addition, the gut microbiome may harbor antibiotic-resistance genes; during antibiotic treatment for other infections or prophylaxis, these genes may be transferred to pathogenic bacteria, making the treatment of PJI more difficult. …”
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Posible impacto en la salud pública del encallamiento de cetáceos en Costa Rica Potential public health impact of the stranding of cetaceans by Olga Rivas-Solano, Claudia Zúñiga-Vega

“…This potentiates the risk of transmission of pathogenic strains from marine mammals to humans and to other animals. …”
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HEMORHEOLOGICAL PROFILE AND LIPID SPECTRUM IN PATIENTS IN THE ACUTE PHASE OF ISCHEMIC STROKE by V. V. Yakusevich, S. V. Lychenko, A. Yu. Malygin

“…At the same time, in the study group the integral aggregation index was 80 % higher (p < 0.01) than that in the control. …”
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Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders by Madia Lozupone, Ivana Leccisotti, Anita Mollica, Giuseppe Berardino, Maria Claudia Moretti, Mario Altamura, Antonello Bellomo, Antonio Daniele, Vittorio Dibello, Vincenzo Solfrizzi, Emanuela Resta, Francesco Panza

“…Complex genetic relationships between neurodegenerative disorders and neuropsychiatric symptoms have been shown, suggesting shared pathogenic mechanisms and emphasizing the potential for developing common therapeutic targets. …”
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SUPPORTIVE CARE AND QUALITY OF LIFE IN MDS: ESSENTIAL MANAGEMENT STRATEGIES by Metban Mastanzade

“…Antimicrobial prophylaxis and vaccinations against common pathogens are critical. Prophylactic measures are especially relevant for patients with neutropenia, where antibiotics, antifungals, and antivirals provide protection. …”
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The Promoting Effects of Fermented Bile Acid on Growth Performance and Intestinal Health of Litopenaeus vannamei Through the Modulation of Lipid Metabolism and Gut Microbiota by Qing Guo, Haili Ma, Lu Zhao, Wenwen Liu, Houfa Zhao, Zuyue Liu, Cuimin Mu, Xuepeng Wang

“…These findings indicate that dietary FBAs and 170HDa have positive effects on growth performance and intestinal health by modulating lipid metabolic profiles, immune responses, the integrity of intestinal wall, and the diversity of intestinal microbes in white shrimp. …”
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From immune evasion to broad in silico binding: computational optimization of SARS-CoV-2 RBD-targeting nanobody by Shuyuan Cao, Bo Sun, Feng Gao, Feng Gao, Feng Gao

“…By enhancing nanobody efficacy, our method provides a viable framework for developing targeted countermeasures against evolving SARS-CoV-2 variants and other pathogens.…”
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Risk factors for weight gain after risk reducing salpingo-oophorectomy in premenopausal patients with hereditary ovarian cancer risk by Surabhi Tewari, Karen Hurley, Meng Yao, Snehi Shah, Melissa Yurch, Anna Chichura, Mariam AlHilli

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Fecal microbiota transplantation from Helicobacter pylori carriers following bismuth quadruple therapy exacerbates alcohol-related liver disease in mice via LPS-induced activation... by Huihui Gao, Hangming Bai, Yanyan Su, Yuting Gao, Hui Fang, Donghang Li, Youren Yu, Xing Lu, Dasheng Xia, Daqing Mao, Yi Luo

“…Results BQT treatment significantly altered the gut microbiota in H. pylori carriers, increasing the abundance of opportunistic pathogens, including Klebsiella pneumoniae, Escherichia coli, Klebsiella quasipneumoniae, and Klebsiella variicola, while decreasing beneficial bacteria such as Bifidobacterium, Eubacterium, Bacteroides, Faecalibacterium, and Blautia. …”
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Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri by Ruth Y. Isenberg, Chandler S. Holschbach, Jing Gao, Mark J. Mandel

“…While c-di-GMP and the enzymes that contribute to its metabolism have been well studied in pathogens, considerably less focus has been placed on c-di-GMP regulation in beneficial symbionts. …”
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Comprehensive surveillance and molecular detection of the Nipah virus in fruit bats (Pteropus vampyrus) across Indonesia: Insights from 2023 to 2024 by Reviany V. Nidom, Setyarina Indrasari, Dhani Prakoso, Astria N. Nidom, Balqis Afifah

“…Background and Aim: The Nipah virus (NiV), a highly pathogenic zoonotic paramyxovirus, presents a severe public health threat due to its high case fatality rate and potential for human-to-human transmission. …”
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Subtyping Influenza A Viruses: Genomic Perspectives on Taxonomy by Dr Andrei Deviatkin, Miss Sofya Feoktistova, Mr Egor Degtyarev, Dr Pavel Volchkov

“…Introduction: Influenza A viruses (IAVs) are pathogens found in natural reservoirs. These viruses are able to cross species barriers, which can lead to disease outbreaks in humans. …”
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Increase of VEGF and Fibronectin expression and ultrastructural alterations of intercellular junctions in a swab negative patient after SARS-COV-2 infection by Carolina Simioni, Juana Maria Sanz, Roberta Gafà, Giovanna Cenacchi, Savino Occhionorelli, Angelina Passaro, Luca Maria Neri

“…In addition to vascular changes, the SARS-CoV-2 infection altered the junctional apparatus among epithelial cells, making the tissue even more fragile and thus susceptible to the entry of pathogens and the development of further infections.…”
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DNA methylation and hydroxymethylation combined with transcriptional profiling identify key regulators of hyperoxia-induced bronchopulmonary dysplasia by Hui-Tao Li, Tao Qian, Hao-Min Zhang, Qiu-Hua Li, Yi-Yun Ma, Yi-Fan Li, Zi-Lu Huang, Dong-Shan Han, Yuan-Ye Dang, Ying-Ying Xiao, Ling Sun, Xue-Yu Chen, Xue-Yan Jiang

“…This study aimed to reveal key regulators and pathogenic genes involved in hyperoxia-induced BPD via DNA (hydroxy)methylation and transcriptional analysis. …”
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Regulation of Intestinal Barrier Function and Gut Microbiota by Hot Melt Extrusion-Drug Delivery System-Prepared Mulberry Anthocyanin in an Inflammatory Bowel Disease Model by Eun-Ji Go, Byeong Ryeol Ryu, Gyeong Ju Gim, Ye Rim Shin, Min Ji Kang, Min Jun Kim, Jong-Suep Baek, Jung Dae Lim

“…Moreover, the formulation modulated gut microbiota composition, promoting beneficial bacteria while suppressing pathogenic strains. HME-MUL-F2 administration led to a significant increase in the Bacteroidetes-to-Firmicutes ratio, which is associated with improved gut health. …”
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Identification and validation of protective glycoproteins in Haemonchus contortus H11 by Hui Liu, Yao Zhang, Jiarui Li, Feng Liu, Lisha Ye, Xin Liu, Chunqun Wang, Min Hu

“…Barbervax is the first and only available vaccine to protect animals against Haemonchus contortus - one of the most pathogenic parasites of small ruminants. This vaccine contains a kind of native antigen called H11, a glycoprotein complex derived from integral gut of this parasite. …”
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Envisioning urban environments resilient to vector-borne diseases: a protocol to study dengue in Vietnam by Praveen Kumar, Thanh H. Nguyen, Phong V.V. Le, Jinhui Yan, Lei Zhao, Brian F. Allan, Andrew W. Taylor-Robinson

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An attenuated coxsackievirus B5 mutant carrying VP1-N157K retains oncolytic potency against non-small cell lung cancer by Lifang Song, Bopei Cui, Qiushuang Gao, Chaoying Hu, Qian wang, Jialu Zhang, Yajing Li, Guanxing Liu, Yulong Fu, Ying Wang, Kelei Li, Xiaotian Hao, Fan Gao, Xing Wu, Qunying Mao, Zhenglun Liang, Yongxin Yu

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