Biofilm-Forming Lactic Acid Bacteria in Sausages: Isolation, Characterization, and Inhibition Using <i>Eisenia bicyclis</i>-Based Nanoparticles by Do Kyung Oh, Du-Min Jo, Minji Kim, Jeong-Bin Jo, Ji-Hwan Choi, Jeong Mi Choi, Geum-Jae Jeong, Se Yun Jeong, Fazlurrahman Khan, Young-Mog Kim

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Global research trends in the relationship between influenza and CD4+ T/CD8+ T cells: A bibliometric analysis by Yanping Zong, Hui Li, Yonglong Chang, Jiajie Li, Lei He, Weibing Shi, Jinchen Guo

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The N‐terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism by Xue Wang, Chunyou Ning, Xingyi Cheng, Zhengzhong Wu, Dongbo Wu, Xuemei Ding, Cunxiang Ju, Zhihang Zhou, Lingfeng Wan, Wei Zhao, Peiliang Shi

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<i>Brucella ceti</i> in Common Dolphins (<i>Delphinus delphis</i>) in Portugal—Characterization of First Isolates by Sandra Cavaco, Miguel L. Grilo, Ricardo Dias, Mónica Nunes, Pedro Pascoal, Marcelo Pereira, Catarina Fogaça, Ana Beatriz Costa, Sofia Pardal, Ana Cristina Ferreira

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From background diabetic retinopathy to its proliferative stage. What is the role of gut microbiota in the trajectory of DR? a Mendelian randomization study with mediation analysis by Yifan Zhou, Jialong Dong, Zhenyu Wang, Chen Huang, Xiaotong Yu, Xinjun Wang, Bo Yang, Yuechen Wu, Qing Peng

“…Conclusion This study pioneers causal longitudinal mapping of GM dynamics across DR progression through integrated genetic prediction and metabolomic mediation analyses, delineating stage-specific microbial drivers, pan-stage pathogens, and metabolite mediators that collectively orchestrate DR pathogenesis. …”
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Associations of serum and bronchoalveolar immunoglobulins with lung microbiota diversity, B-cell memory phenotypes, and COPD morbidity and exacerbations by Vickram Tejwani, Nirupama Putcha, Han Woo, Chen Liu, David Lafon, Neil E. Alexis, Antoine Azar, R. Graham Barr, Igor Barjaktarevic, Russell P. Bowler, Alejandro Comellas, David J. Couper, Ashraf Fawzy, MeiLan K. Han, Nadia N. Hansel, Robert J. Kaner, Jerry A. Krishnan, Nathaniel Marchetti, Fernando J. Martinez, Jill Ohar, Wanda O’Neal, Victor E. Ortega, Robert Paine III, Tess D. Pottinger, Martin Stämpfli, Lisa Ruvuna, Prescott G. Woodruff, Christine M. Freeman, Yvonne J. Huang, Jeffrey L. Curtis

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Microbiome profiling reveals gut bacterial species associated with rapid lung function decline in people with HIV by Xiangning Bai, Xiangning Bai, Xiangning Bai, Sajan C. Raju, Sajan C. Raju, Andreas Dehlbæk Knudsen, Rebekka Faber Thudium, Nicoline Stender Arentoft, Marco Gelpi, Marco Gelpi, Safura-Luise Heidari, Ken M. Kunisaki, Ken M. Kunisaki, Karsten Kristiansen, Karsten Kristiansen, Johannes Roksund Hov, Johannes Roksund Hov, Susanne Dam Nielsen, Susanne Dam Nielsen, Susanne Dam Nielsen, Marius Trøseid, Marius Trøseid, Marius Trøseid

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Therapeutic potential of Litsea cubeba essential oil in modulating inflammation and the gut microbiome by Liqiong Xia, Ran Li, Ran Li, Ting Tao, Ruimin Zhong, Haifang Du, Ziling Liao, Zhanghua Sun, Changqiong Xu, Changqiong Xu

“…Inflammation, a sophisticated and delicately balanced physiological mechanism, is paramount to the host’s immunological defense against pathogens. However, unfettered and excessive inflammation can be instrumental in engendering a plethora of chronic ailments and detrimental health repercussions, notably within the gastrointestinal tract. …”
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Contribution of malnutrition to infant and child deaths in Sub-Saharan Africa and South Asia by Khatia Munguambe, Quique Bassat, Mahbubur Rahman, Sibone Mocumbi, Cynthia G Whitney, Amy Wise, Shams El Arifeen, Meerjady Sabrina Flora, Soter Ameh, Emily S Gurley, Mustafizur Rahman, Ariel Nhacolo, Cheick Bougadari Traore, Inacio Mandomando, Clara Menendez, Janet Agaya, Jane Juma, Shabir A Madhi, Tadesse Gure, George Aol, Hennie Lombaard, Ziyaad Dangor, James Bunn, Samba O Sow, Amara Jambai, Dickson Gethi, Sanwarul Bari, Natalia Rakislova, Tacilta Nhampossa, Maria Maixenchs, Mohammed Kamal, Joseph Oundo, Lola Madrid, Tahmina Shirin, Ikechukwu Udo Ogbuanu, Addisu Alemu, Hailemariam Legesse, Awa Traore, Portia C Mutevedzi, Helina Heluf, Victor Akelo, Dickens Onyango, Richard Omore, Yasmin Adam, Peter Otieno, Margaret Mannah, Karen L Kotloff, Milagritos D Tapia, Rima Koka, Mohammad Zahid Hossain, Dickens Kowuor, Tom Sesay, James Squire, Francis Moses, Kitiezo Aggrey Igunza, Andrew Moseray, Afruna Rahman, Nana Kourouma, Seydou Sissoko, Rosauro Varo, Sana Mahtab, Martin Hale, Jeanie du Toit, Zachary J Madewell, Dianna M Blau, Fatima Solomon, Gillian Sorour, Jeannette Wadula, Karen Petersen, Sanjay G Lala, Sithembiso Velaphi, Richard Chawana, Nellie Myburgh, Shahana Parveen, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Dilruba Ahmed, Fikremelekot Temesgen, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian MS Orlien, Solomon Ali, Peter Nyamthimba Onyango, Richard Oliech, Joyce Akinyi Were, Thomas Misore, Harun Owuor, Christopher Muga, Christine Ochola, Ashka Mehta, Brigitte Gaume, Adama Mamby Keita, Diakaridia Kone, Diakaridia Sidibe, Doh Sanogo, Kounandji Diarra, Tiéman Diarra, Kiranpreet Chawla, Zara Manhique, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, Alim Swaray-Deen, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Erick Kaluma, Oluseyi Balogun, Carrie Jo Cain, Solomon Samura, Samuel Pratt, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Francis Smart, Sartie Kenneh, Ferdousi Begum, Priya Mehta-Gupta Das, Ogony Benard Oluoch, Caleb K Sagam, Ronita Luke, Milton Kincardett, Elisio G Xerinda, Markus Roos Breines, Ketema Degefa, J. Anthony G Scott, Kazi Munisul Islam, Parminder S Suchdev, Nelesh P. Govender, Peter J. Swart, Nawshad Uddin Ahmed, Alexander M. Ibrahim, Sharon M. Tennant, Carol L. Greene, J. Kristie Johnson, Karen D. Fairchild, Uma U. Onwuchekwa, Joseph Bangura

“…These findings highlight the need for integrated interventions addressing both malnutrition and infectious diseases to effectively reduce under-5 mortality.…”
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The effects of candidate probiotic strains on the gut environment in dextran sulfate sodium-induced colitis mouse by Kung Ahn, Kyung-Wan Baek, Kyeongeui Yun, Yunseok Oh, Yong Sung Kim, Eunok Im, Yunna Lee, Jieun Choi, Eun-Ji Song, Yong-Soo Park, Dong Ho Lee, Wonsuk Lee, Do Yup Lee, Kyudong Han, Yong Ju Ahn

“…Notably, functional analyses using PICRUSt2 revealed a sustained decrease in the siderophore biosynthesis pathway (ko01053), suggesting that these candidate probiotic strains may inhibit siderophore production—a pivotal mechanism by which pathogenic bacteria aggravate intestinal inflammation. …”
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Ge-SAND: an explainable deep learning-driven framework for disease risk prediction by uncovering complex genetic interactions in parallel by Lihang Ye, Liubin Zhang, Bin Tang, Junhao Liang, Ruijie Tan, Hui Jiang, Wenjie Peng, Nan Lin, Kun Li, Chao Xue, Miaoxin Li

“…Ge-SAND leverages genotype and genomic positional information to identify both intra- and interchromosomal interactions associated with disease phenotypes, providing comprehensive insights into pathogenic mechanisms crucial for disease risk prediction. …”
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Genomic insights reveal community structure and phylogenetic associations of endohyphal bacteria and viruses in fungal endophytes by Efraín Escudero-Leyva, Michal Belle, Abolfazl DadkhahTehrani, James N. Culver, Marcelo Araya-Salas, Joseph P. Kutza, Natasha Goldson, Max Chavarría, Priscila Chaverri

“…While endohyphal bacteria have been shown to influence fungal pathogenicity, secondary metabolism, and adaptability, much remains unknown about their diversity and host specificity. …”
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Co-occurrence of multiple pathologies in a case of frontotemporal dementia with TBK1 mutation: first in vivo detection of alpha-synuclein and tau co-pathology by Alexander M. Bernhardt, Sigrun Roeber, Viktoria Ruf, Elisabeth Wlasich, Endy Weidinger, Sebastian Longen, Svenja V. Trossbach, Johannes Gnörich, Matthias Brendel, Jochen Herms, Armin Giese, Günter U. Höglinger, Johannes Levin

“…Abstract We present the case of a 74-year-old woman with behavioral variant frontotemporal dementia (bvFTD) linked to a pathogenic TANK-binding kinase 1 (TBK1) mutation (c.1349_1352del; p.Ile450Lysfs*15). …”
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Characterization of Klebsiella pneumoniae carbapenemase (KPC)-14, a KPC variant conferring resistance to ceftazidime-avibactam in the extensively drug-resistant ST463 Pseudomonas a... by Yanyan Xiao, Le Wang, Huiqiong Jia, Yan Jiang, Yue Li, Jiamin Han, Shengchao Li, Yaxi Gu, Qing Yang

“…The blaKPC-14 gene carried by PCTs was integrated into the chromosome and exhibited stability throughout bacterial inheritance. …”
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Effectiveness of probiotic therapy in chronic purulent maxillary sinusitis in patients with type 1 diabetes mellitus by O.O. Mazur, N.V. Pashkovska, O.H. Plaksyvyi, I.O. Tsaryk, I.V. Kalutskyi, N.M. Kaspruk, Ya.M. Teleki

“…The results of treatment with a multiprobiotic showed significant effectiveness: a decrease in the level of endogenous intoxication, stimulation of factors of non-specific resistance and influence on conditionally pathogenic microflora.…”
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Antimicrobial Efficacy of Impregnated Human Acellular Dermal Substitutes in Burn Wound Models by Marianna Hajská, Elena Kurin, Silvia Bittner Fialová, Marian Vidiščák, Arpád Panyko

“…Burn wound infections remain a major clinical challenge due to delayed healing, scarring, and the risk of sepsis, especially when complicated by multidrug-resistant (MDR) Gram-negative pathogens and biofilm formation. Acellular dermal matrices (ADMs) are widely used in reconstructive and burn surgery, yet they lack intrinsic antimicrobial activity, necessitating their combination with topical agents. …”
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Establishment and application of a grading diagnostic model for early detection of severe fever with thrombocytopenia syndrome by Yao Hao, Yingchun Sun, Zhiyu Pan, Jing Sun, Manman Liang, Aiping Zhang, Jianghua Yang

“…This study devised a direct and practical approach to diagnose and better understand the role of pathogens in the disease progression.…”
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Genomic insights and epidemiology of mcr-1-Carrying Escherichia albertii isolated from agricultural soil in China by Yu Yang, Wenhong Liu, Zanzan Zhao, Kexin Guo, Xinrui Wang, Zhenghao Lou, Xiaolu Yang, Lu Gong, Kun Wang, Xiaojing Liu, Hao Xu, Qiyu Liu, Beiwen Zheng, Xiawei Jiang

“…Abstract Background Polymyxins are critical in treating multidrug-resistant Gram-negative bacteria infections, yet their overuse has spurred the emergence of polymyxin-resistant pathogens globally. This study aims to analyze the genomic characteristics of the Escherichia albertii strain 6S-65-1 carrying the mcr-1 gene and to investigate the global epidemiology of mcr-1-carrying E. albertii strains. …”
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Liver Transcriptome Analysis Reveals a Potential Mechanism of Heat Stress Increasing Susceptibility to <i>Salmonella</i> Typhimurium in Chickens by Qi Zhang, Yvqing Zhu, Zixuan Wang, Qinghe Li, Guiping Zhao, Qiao Wang

“…This study elucidates the intrinsic regulatory relationships through which heat stress promotes <i>Salmonella</i> pathogenicity and inflammatory responses, providing important insights for disease-resistant poultry breeding and prevention strategies.…”
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Metabolome-wide associations with short-term exposure to PM2.5-bound polycyclic aromatic hydrocarbons: a study in older adults by Haoneng Hu, Quan Zhou, Kang Cao, Yu Jiang, Jianjun Xiang, Jing Wu, Jin Li, Zhiwei Chen, Shuling Kang, Dandan Zhu, Huaying Lin, Chuancheng Wu

“…Our findings suggest that the cholesterol and citric acid metabolites, as well as the cholesterol biosynthesis and citric acid cycle pathways they affect, may play important roles in the health damage caused by PAHs, providing potential insights into the pathogenic processes underlying the impact of PM2.5-bound PAHs.…”
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