Construction of several plant expression vectors using multiple cell wall degrading enzyme genes from Trichoderma harzianum and rice transformation by LIU Mei, SUN Zong-xiu, XU Tong

“…In order to enhance rice resistance against fungal pathogens by applying the synergistic interaction of different cell wall degrading enzymes from Trichoderma, three different cell wall degrading enzyme genes from Trichoderma harzianum PI were placed respectively downstream of Act1 promoter. …”
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Deciphering the Role of Innate Lymphoid Cells Group 3 in the Gut Microenvironment: A Narrative Review of Their Novel Contributions to Autoimmune Disease Pathogenesis by Wang H, Wang T, He Z, Wen C, Huang L, Wang M

“…ILC3s exert their immune function through cytokine secretion, patrolling actions and the generation of memory ILC3s that aid in repairing epithelial tissue and preserving mucosal barrier integrity. Moreover, dysregulation of ILC3s function has been implicated in the pathogenesis and progression of autoimmune diseases. …”
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The complete mitochondrial genome of Urocitellus undulatus and its phylogenetic analysis by Zimeng Liu, Lei Chen, Yuran Pang, Xing Yang, Fengyan Zhang, Tangxin Liu, Xinhui Zhang, Yayun He, Xu He, Jiaxin Wang, Qingsong Sun

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Epidemiology and Genetic Characterization of Distinct Ebola Sudan Outbreaks in Uganda by Francesco Branda, Massimo Ciccozzi, Fabio Scarpa

“…Our findings underscore the importance of integrated genomic and epidemiological surveillance in understanding SUDV transmission dynamics. …”
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A self-powered millifluidic device driven by triboelectric generator for the label-free and real-time detection of DNA hybridization by Tara Ghafouri, Sheida Bagherzadeh‑Nobari, Negin Manavizadeh

“…For this purpose, the biosensing interface is set up in a millifluidic chamber, integrated into the dual-mode conductor-to-dielectric triboelectric generator to stimulate the genosensor and scavenge the signal simultaneously. …”
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Chromosomal Microarray Analysis in Spina Bifida: Genetic Heterogeneity and Its Clinical Implications by Himani Pandey, Jyoti Sharma, Sourabh Kumar, Nakul Mohan, Vishesh Jain, Anjan Kumar Dhua, Devendra Kumar Yadav, Ashish Kumar Dubey, Prativa Choudhury, Prabudh Goel

“…While whole exome sequencing has identified several pathogenic variants in Indian cohorts, the role of chromosomal imbalances and long contiguous stretches of homozygosity (LCSHs) remains largely unexplored in this population. …”
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A computational and experimental approach to studying NFkB signaling in response to single, dual, and triple TLR signaling by Thalia Newman, Annarose Taylor, Sakhi Naik, Swati Pandey, Kimberly Manalang, Robert A. Kurt, Chun Wai Liew

“…Modeling and experimental data were used to evaluate how monocytes would respond to dual TLR4/TLR5 and dual TLR4/TLR7 signaling analogous to how the cells would respond to simultaneously encountering different types of pathogens. Both TLR4/TLR5 and TLR4/TLR7 signaling resulted in a decreased NFkB response relative to signaling through a single TLR. …”
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A transferable machine learning model for real-time forecast of epidemic dynamics and pre-trigger event warning by Enpei Chen, Xiong Yu

“…Abstract Wastewater-based epidemiology (WBE) is emerging as an effective tool to provide early warnings of potential disease outbreaks within communities through detecting the presence of pathogens in wastewater before clinical cases are reported. …”
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A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses. by William T Harvey, Vinny Davies, Rodney S Daniels, Lynne Whittaker, Victoria Gregory, Alan J Hay, Dirk Husmeier, John W McCauley, Richard Reeve

“…Surface antigens of pathogens are commonly targeted by vaccine-elicited antibodies but antigenic variability, notably in RNA viruses such as influenza, HIV and SARS-CoV-2, pose challenges for control by vaccination. …”
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Groundwater in Germany: challenges, solutions, and the BMBF funding measure LURCH: sustainable groundwater management by Sarah Fieger, Thomas Track

“…The research tackles pollution risks from nitrate, trace substances, and pathogens while advancing analytical methods and technological innovations, including in-situ treatment and monitoring. …”
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Phytogenic synthesis and antimicrobial activity of ZnO nano bow ties (ZnO NBTs): An experimental and computational study by Manju Manuel, M. Gomathy, Manikantan Pappuswamy, Krishna Bisetty, Suvardhan Kanchi

“…The ZnO NBTs complexes formed stronger hydrophobic interactions and hydrogen bonds with amino acid residues of Escherichia coli than with Klebsiella pneumoniae. This integrated experimental and computational study underscores the potential of the use of ZnO NBTs as a sustainable and effective strategy to combat bacterial pathogens. …”
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Diagnostic model for COPD patients with nocardia infection: a study based on clinical features and risk factors by Kai Zhang, Kangli Yang, Hongmin Wang

“…COPD patients exhibit heightened susceptibility to opportunistic pathogens like Nocardia species due to compromised airway defenses and frequent glucocorticoid/immuno-suppressant use. …”
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Deciphering the role of molecular mimicry in the etiopathogenesis of Autoimmune Hemolytic Anemia using an immunoinformatics approach. by Pratyusha Patidar, Arihant Jain, Tulika Prakash

“…These findings suggest that infection-causing pathogens and gut microbes might have a plausible association with AIHA in the context of molecular mimicry.…”
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Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses. by Vanessa Herder, Kieran Dee, Joanna K Wojtus, Ilaria Epifano, Daniel Goldfarb, Christoforos Rozario, Quan Gu, Ana Da Silva Filipe, Kyriaki Nomikou, Jenna Nichols, Ruth F Jarrett, Andrew Stevenson, Steven McFarlane, Meredith E Stewart, Agnieszka M Szemiel, Rute M Pinto, Andreu Masdefiol Garriga, Chris Davis, Jay Allan, Sheila V Graham, Pablo R Murcia, Chris Boutell

“…Fever is an evolutionarily conserved host response to microbial infection that can influence the outcome of viral pathogenicity and regulation of host innate and adaptive immune responses. …”
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DAGSLAM: causal Bayesian network structure learning of mixed type data and its application in identifying disease risk factors by Yuanyuan Zhao, Jinzhu Jia

“…The algorithm integrates continuous and categorical variables through a tailored loss function, enhancing its applicability to real-world epidemiological datasets. …”
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Transformative advances in veterinary laboratory practices: Evaluating the impact of preliminary training in Khyber Pakhtunkhwa and Balochistan provinces of Pakistan by Javed Khan, Asghar Ali, Shaukat Khan, Murad Khan, Saima Mohsin, Cecelia Madsen

“…This comprehensive strategy provides a basis for improving biosafety and biosecurity measures within laboratories, thereby contributing to the global effort to mitigate unauthorized access to high-risk pathogens.…”
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Oropharyngeal dysbiosis affects postoperative tissue reparative capacity in patients with congenital disorders of maxillofacial region by Zaira F. Kharaeva, Vladimir A. Vissarionov, Sofyat M. Mustafaeva, Melena M. Yusupova, Alina R. Shogenova, Dzhamilya. Sarakaeva, Diana V. Degoeva, Vladimir V. Smeianov

“…Conclusion — Our study demonstrated the need for preoperative eradication of potential pathogens (e.g., Staphylococcus aureus, Klebsiella spp., Candida spp. and Streptococcus spp.), preferably, via using non-antibiotic approaches, such as probiotics and phage therapy, as well as supportive integrative therapy (e.g., using antioxidants).…”
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Evaluation of synergistic effect of entomopathogenic fungi Beauveria bassiana and Lecanicillium lecacii on the mosquito Culex quinquefaciatus. by Aditya Shankar Kataki, Francesco Baldini, Anjana Singha Naorem

“…Developing novel strategies for mosquito control without jeopardizing the environmental conditions has always been a topic of discussion and research. Integrated Vector Management (IVM) emphasizes a comprehensive approach and use of a range of strategies for vector control. …”
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Modeling Alzheimer’s Disease: A Review of Gene-Modified and Induced Animal Models, Complex Cell Culture Models, and Computational Modeling by Anna M. Timofeeva, Kseniya S. Aulova, Georgy A. Nevinsky

“…It is imperative to underscore the significance of integrating diverse modeling techniques in elucidating pathogenic mechanisms in their entirety.…”
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Effects of dietary supplementation with Bacillus subtilis and bacteriophage on growth performance, intestinal morphology and microbiota structure in 0–90 d MaGang geese by Chenyu Zhu, Yongquan Luo, Kunjie Xu, Yong Li, Yuanhao Han, Zhiyuan Liu, Xiujin Li, Danning Xu, Yunbo Tian, Yunmao Huang, Zhongping Wu, Xumeng Zhang

“…Notably, the combined treatment demonstrated synergistic effects in reducing serum and aquatic endotoxin levels while suppressing pathogenic bacteria (Escherichia coli and Salmonella) in water systems. …”
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