Endophytic fungi as a source of antimicrobial compounds against emerging methicillin-resistant Staphylococcus aureus by Shefali Bansal, Mahavir Joshi, Prachi Mahajan, Smile Sharma, Sukhminderjit Kaur, Babita Thakur, Prabhjot Singh Jassal, Ranjan Singh, Manikant Tripathi

“…Among the most concerning resistant pathogens is Methicillin-resistant Staphylococcus aureus (MRSA), a multidrug-resistant bacterium whose genetic adaptability and rapid evolution have rendered many conventional antibiotics ineffective. …”
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Insecticidal Activity of Lectin Preparations from <i>Moringa oleifera</i> Lam. (Moringaceae) Seeds Against <i>Alphitobius diaperinus</i> (Panzer) (Coleoptera: Tenebrionidae) by Nataly Diniz de Lima Santos, Patryck Érmerson Monteiro dos Santos, Thiago Lucas da Silva Lira, Aline Rodrigues da Silva Santos, Juliane Nancy de Oliveira Silva, Alícia Natalie Silva dos Santos, Marcus Mello Rego de Amorim, Mércia Rodrigues Barros, Luana Cassandra Breitenbach Barroso Coelho, Patrícia Maria Guedes Paiva, Thâmarah de Albuquerque Lima, Gustavo Ferreira Martins, Thiago Henrique Napoleão, Emmanuel Viana Pontual

“…The lesser mealworm, <i>Alphitobius diaperinus</i>, is a widespread pest in poultry farming, causing economic losses and facilitating the spread of pathogens. Current control methods rely heavily on synthetic insecticides, which raise environmental concerns and contribute to resistance. …”
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Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease by Karthik Subramanian, Federico Iovino, Vasiliki Tsikourkitoudi, Padryk Merkl, Sultan Ahmed, Samuel B Berry, Marie‐Stephanie Aschtgen, Mattias Svensson, Peter Bergman, Georgios A Sotiriou, Birgitta Henriques‐Normark

“…Abstract Cholesterol‐dependent cytolysins (CDCs) are essential virulence factors for many human pathogens like Streptococcus pneumoniae (pneumolysin, PLY), Streptococcus pyogenes (streptolysin O, SLO), and Listeria monocytogenes (Listeriolysin, LLO) and induce cytolysis and inflammation. …”
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Physiologically relevant coculture model for oral microbial-host interactions by Zeyang Pang, Nicole M. Cady, Lujia Cen, Thomas M. Schmidt, Xuesong He, Jiahe Li

“…In addition, the model enabled precise evaluation of antibiotic efficacy against intracellular pathogens. Finally, we validate the ability of the asymmetric system to support the proliferation of a more oxygen-sensitive oral pathobiont, Porphyromonas gingivalis. …”
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White Blood Cell Detection Based on FBDM-YOLOv8s by Borui Sun, Xiangsuo Fan, Jie Meng, Jinfeng Wang, Huajin Chen, Lei Liu

“…White blood cells, also known as immune cells, help the body resist infectious diseases and foreign pathogens as part of the immune system. This article proposes a white blood cell detection method based on an improved YOLOv8s to enhance the accurate detection of different categories of normal white blood cells. …”
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Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence by Changge Guan, Marcelo D. T. Torres, Sufen Li, Cesar de la Fuente-Nunez

“…Abstract The rise of antibiotic-resistant pathogens, particularly gram-negative bacteria, highlights the urgent need for novel therapeutics. …”
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Aminoglycoside resistance dynamics and its predictive value for carbapenem resistance in multidrug-resistant Acinetobacter baumannii and Klebsiella pneumoniae by Bence Sajerli, Klára Makai, Lóránt Lakatos, Ágnes Sarkadi-Nagy, Katalin Burián, László Orosz

“…Objective: The rise of multidrug-resistant bacterial pathogens, including carbapenem-resistant Acinetobacter baumannii (CRAB) and Klebsiella pneumoniae (CRKP), poses a global healthcare challenge. …”
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Myricetin Potentiates Antibiotics Against Resistant <i>Pseudomonas aeruginosa</i> by Disrupting Biofilm Formation and Inhibiting Motility Through FimX-Mediated c-di-GMP Signaling I... by Derong Zeng, Fangfang Jiao, Yuqi Yang, Shuai Dou, Jiahua Yu, Xiang Yu, Yongqiang Zhou, Juan Xue, Xue Li, Hongliang Duan, Yan Zhang, Jingjing Guo, Wude Yang

“…Hence, myricetin may act as a c-di-GMP inhibitor, reversing biofilm-mediated resistance in <i>Pseudomonas aeruginosa</i> and augmenting antibiotic efficacy. This integrated experimental and computational approach provides a framework for developing anti-virulence and antibiotic combination therapies against recalcitrant Gram-negative pathogens.…”
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Protective effect of interferon type I on barrier function of human airway epithelium during rhinovirus infections in vitro by Helena Boland, Adrian Endres, Ralf Kinscherf, Ralf Schubert, Beate Wilhelm, Hans Schwarzbach, Danny Jonigk, Peter Braubach, Gernot Rohde, Carla Bellinghausen

“…Abstract The airway epithelium provides a crucial barrier against infection with respiratory pathogens. This barrier can be impaired following viral infection, paving the way for bacterial superinfections. …”
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Screening of Rice Genotypes for Resistance Against Bacterial Blight Disease by Jyoti P. Jirankali, C. A. Deepak, B. S. Chethana, G. M. Sandesh, G. Nikhil, M. P. Rajanna

“…Host Plant resistance is an important component of an integrated management program for this disease. Among the 102 rice genotypes screened under natural epiphytotic condition at Zonal Agricultural Station, V. …”
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Impact of Antibacterial Agents in Horticulture: Risks to Non-Target Organisms and Sustainable Alternatives by Mirza Abid Mehmood, Muhammad Mazhar Iqbal, Muhammad Ashfaq, Nighat Raza, Jianguang Wang, Abdul Hafeez, Samah Bashir Kayani, Qurban Ali

“…To mitigate these hazards, sustainable alternatives such as integrated plant disease management (IPDM) and biotechnological solutions are essential. …”
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Intervention strategies for Parkinson’s disease: the role of exercise and mitochondria by Ganggang Xu, Chunlian Ma, Chunlian Ma, Yi Yang, Yi Yang

“…Parkinson’s disease (PD), a progressive neurodegenerative disorder with complex pathogenic mechanisms, exhibiting rising prevalence alongside global population aging. …”
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Metaproteomics in the One Health framework for unraveling microbial effectors in microbiomes by Robert Heyer, Maximilian Wolf, Dirk Benndorf, Sergio Uzzau, Jana Seifert, Lucia Grenga, Martin Pabst, Heike Schmitt, Bart Mesuere, Tim Van Den Bossche, Sven-Bastiaan Haange, Nico Jehmlich, Mariagrazia Di Luca, Manuel Ferrer, Sergio Serrano-Villar, Jean Armengaud, Helge B. Bode, Patrick Hellwig, Catherine Robbe Masselot, Renaud Léonard, Paul Wilmes

“…Abstract One Health seeks to integrate and balance the health of humans, animals, and environmental systems, which are intricately linked through microbiomes. …”
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Bioprotection of the Button Mushroom from Pests and Diseases by Dejan Marčić, Svetlana Milijašević-Marčić, Tanja Drobnjaković, Jelena Luković, Ljiljana Šantrić, Nikola Grujić, Ivana Potočnik

“…Bioprotection agents require inclusion in the integrated pest and disease management (IPDM) programs in order to achieve their full effectiveness.…”
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Harnessing the synergy of Urochloa brizantha and Amazonian Dark Earth microbiomes for enhanced pasture recovery by Anderson Santos de Freitas, Luís Felipe Guandalin Zagatto, Gabriel Silvestre Rocha, Franciele Muchalak, Guilherme Lucio Martins, Solange dos Santos Silva-Zagatto, Rogério Eiji Hanada, Aleksander Westphal Muniz, Siu Mui Tsai

“…The findings highlight the potential for pasture ecological rehabilitation and underscore the benefits of integrating plant and soil management strategies to optimize soil characteristics.…”
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The Impact of Antibiotic Therapy on Intestinal Microbiota: Dysbiosis, Antibiotic Resistance, and Restoration Strategies by Gaia Cusumano, Giancarlo Angeles Flores, Roberto Venanzoni, Paola Angelini

“…The human gut microbiota—an intricate and dynamic ecosystem—plays a pivotal role in metabolic regulation, immune modulation, and the maintenance of intestinal barrier integrity. Although antibiotic therapy is indispensable for managing bacterial infections, it profoundly disrupts gut microbial communities. …”
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Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy by Claude Mambo Muvunyi, Jean Claude Semuto Ngabonziza, Emmanuel Edwar Siddig, Ayman Ahmed

“…We recommend exploring cost-effective human and/or animal vaccination mechanisms for RVF, integrating AI-powered drones into dis-ease vectors surveillance and control, and the routine implementation of genomics-enhanced xenosurveillance to monitor changes in pathogens and vectors dynamics in order to inform poli-cymaking and guide the control interventions.…”
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Intestinal Insights: The Gut Microbiome’s Role in Atherosclerotic Disease: A Narrative Review by Luana Alexandrescu, Adrian Paul Suceveanu, Alina Mihaela Stanigut, Doina Ecaterina Tofolean, Ani Docu Axelerad, Ionut Eduard Iordache, Alexandra Herlo, Andreea Nelson Twakor, Alina Doina Nicoara, Cristina Tocia, Andrei Dumitru, Eugen Dumitru, Laura Maria Condur, Cristian Florentin Aftenie, Ioan Tiberiu Tofolean

“…We emphasize the potential of integrating microbiota modulation with traditional cardiovascular care, offering a holistic approach to managing atherosclerosis. …”
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Diabetes and gut microbiome by Kateřina Olša Fliegerová, Tiziana Maria Mahayri, Tiziana Maria Mahayri, Hana Sechovcová, Hana Sechovcová, Chahrazed Mekadim, Jakub Mrázek, Radka Jarošíková, Radka Jarošíková, Michal Dubský, Vladimíra Fejfarová, Vladimíra Fejfarová

“…Intestinal microbes and their fermentation products have an important impact on host metabolism, immune system, nutrient digestion and absorption, gut barrier integrity and protection against pathogens. This review summarizes the current evidence on the changes in gut microbial populations in both types of diabetes mellitus. …”
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Research on the Identification of Wheat Fusarium Head Blight Based on Multispectral Remote Sensing from UAVs by Ping Dong, Ming Wang, Kuo Li, Hongbo Qiao, Yuyang Zhao, Fernando Bacao, Lei Shi, Wei Guo, Haiping Si

“…Fusarium head blight (FHB), a severe ailment triggered by fungal pathogens, poses a considerable risk to both the yield and quality of winter wheat worldwide, underscoring the urgency for precise detection measures that can effectively mitigate and manage the spread of FHB. …”
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