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2721
Wastewater-Based Surveillance of Human Adenoviruses in Italy: Quantification by Digital PCR and Molecular Typing via Nanopore Amplicon Sequencing
Published 2025-05-01“…Our findings highlight the value of integrating quantitative and high-resolution molecular tools in WBE to improve surveillance and better understand the epidemiology of viral pathogens circulating in the human population.…”
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2722
Roles of arbuscular mycorrhizal fungi in plant growth and disease management for sustainable agriculture
Published 2025-07-01“…AMF also engage in synergistic interactions with rhizosphere microbiota such as Trichoderma, Pseudomonas, and Bacillus, enhancing their collective biocontrol efficacy against a broad spectrum of soil-borne pathogens, including fungi, bacteria, and nematodes. …”
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2723
Development of the MTB/IC LAMP-MS Assay for Rapid Detection of <i>Mycobacterium tuberculosis</i>
Published 2025-04-01“…<b>Methods:</b> In this study, we developed the MTB/IC LAMP-MS assay, a novel molecular diagnostic platform that integrates loop-mediated isothermal amplification (LAMP) technology with microscope (MS) detection. …”
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2724
Therapeutic Opportunities in Overcoming Premature Termination Codons in Epidermolysis Bullosa via Translational Readthrough
Published 2025-08-01“…Epidermolysis Bullosa (EB) comprises a group of inherited blistering disorders caused by pathogenic variants in genes essential for skin and mucosal integrity. …”
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2725
Visualizing germination of microbiota endospores in the mammalian gut
Published 2022-12-01“…Transmission of bacterial endospores between the environment and people and the following germination in vivo play critical roles in both the deadly infections of some bacterial pathogens and the stabilization of the commensal microbiotas in humans. …”
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2726
Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host
Published 2025-08-01“…Abstract Phage‐mediated horizontal transfer of virulence genes can enhance the transmission and pathogenicity of Salmonella enterica (S. enterica), a process potentially regulated by its regulatory mechanisms. …”
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2727
Bioactive Potential of Some <i>Bacillus thuringiensis</i> Strains from Macapá, Amazon, Brazil, Against the Housefly <i>Musca domestica</i> (Diptera: Muscidae) Under Laboratory Cond...
Published 2024-12-01“…The high pathogenic activity of <i>Bacillus thuringiensis</i> (<i>Bt</i>) strains against various insect orders has positioned it as the most effective, environmentally safe, and sustainable approach to integrated insect management. …”
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2728
Molecular and Biochemical Characterization of Recombinant Guinea Pig Tumor Necrosis Factor-Alpha
Published 2015-01-01“…TNF-α is essential for the development of a protective immune response to some pathogens, for example, Mycobacterium tuberculosis, by synergizing with other cytokines. …”
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2729
Acoustic therapy for allergic rhinitis and chronic rhinosinusitis: modulating microbiome, immunity and well-being
Published 2025-08-01“…Given this limited but expanding body of evidence, we integrate interdisciplinary insights from respiratory medicine, immunology, and microbiome science to provide a translational framework for future research. …”
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2730
Effects of a Novel COL4A3 Homozygous/Heterozygous Splicing Mutation on the Mild Phenotype in a Family With Autosomal Recessive Alport Syndrome and a Literature Review
Published 2025-02-01“…Complementary analysis of clinical data was carried out, and we explored the expression and function of the variants to verify their pathogenicity. Results A splicing mutation (c.687 + 1G > T) in COL4A3 was found in a Chinese family. …”
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2731
Physicochemical characteristics, volatile components and bioactivities of fermented seasoning sauce produced from cricket (Acheta domesticus) meal
Published 2025-06-01“…Two non-pathogenic food-derived bacteria, Staphylococcus piscifermentans TISTR 824 and Halobacillus sp. …”
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2732
SLC26A4 C.317C > A Variant: Functional Analysis and Patient‐Derived Induced Pluripotent Stem Line Development
Published 2025-04-01“…This gene predominantly harbors pathogenic variants, including splice, nonsense, and missense. …”
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2733
Comparative genomics analysis of Bacillus altitudinis G03 provides insights into its biocontrol and probiotic traits
Published 2025-07-01“…In vitro experiments confirm that G03 successfully inhibits the growth of several fungi and pathogenic bacteria, hydrolyzes protein and cellulose, and is capable of forming strong adhesive biofilms. …”
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2734
Immune and Safety Analysis of <i>ultra</i>IPV<sup>TM</sup>, a Novel UVC-Inactivated Polio Vaccine
Published 2025-06-01“…The potential of UVC inactivation to maintain structural integrity and immunogenicity of viral antigens, while circumventing safety issues with conventional vaccines, could bolster global polio eradication efforts and holds promise for applications to numerous other viral pathogens. …”
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2735
Mature Tiankengs are biodiversity hotspots of soil microorganisms in the karst region
Published 2025-01-01“…The microbial functions of human pathogenic, aromatic compounds and plastic degradation associated were higher in Tiankeng than in the outside. …”
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2736
Potential molluscicidal and antimicrobial activities of rare earth elements against the land snail Theba pisana and certain microorganisms
Published 2025-06-01“…LREEs-based formulations exhibited marked antimicrobial activity against all tested pathogens by the measured inhibition zones. Results highlight the promising application of LREEs in integrated pest and microbial disease management. …”
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2737
Antifibrotic therapies for metabolic dysfunction-associated steatotic liver diseaseKeypoints
Published 2025-08-01“…The arsenal of therapies for MASLD is rapidly expanding and includes macrophage transplantation, hepatocyte-specific oligonucleotides, as well as CAR T cell-based therapies. Integrating these novel therapeutic concepts into stage-specific and/or combination therapies targeting divergent pathogenic mechanisms and cell types is the focus of ongoing research, which may lead to fibrosis reduction in a higher percentage of patients with MASH.…”
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2738
Mycotoxins in Broiler Production: Impacts on Growth, Immunity, Vaccine Efficacy, and Food Safety
Published 2025-05-01“…The review further examines the synergistic interactions between mycotoxins and pathogens, the physiological and histopathological changes in exposed birds, and the implications for public health. …”
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2739
Zr‐MOF Carrier‐Enhanced Dual‐Mode Biosensing Platforms for Rapid and Sensitive Diagnosis of Mpox
Published 2024-10-01“…Validation is conducted using 50 clinical samples, which is 100% concordant to those of quantitative polymerase chain reaction (qPCR), indicating that Ru@U6‐Ru/Pt NPs‐based dual‐mode sensing platforms showed great promise as rapid, sensitive, and accurate tools for diagnosis of the nucleic acid of MPXV and other infectious pathogens.…”
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2740
Potential of the livestock industry environment as a reservoir for spreading antimicrobial resistance
Published 2025-02-01“…Intensive livestock farming is an important source of AMR genes and environmental bacteria contamination and possible transfer to human pathogens. Bacteria intrinsic antibiotic resistant which are independent of antibiotic use further complicate the AMR issue and increase the risk of morbidity and mortality following infections from AMR bacteria. …”
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