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2601
Microbiome-driven gene dysregulation in oesophageal cancer: a multi-omics analysis
Published 2025-07-01“…The observed gene expression shifts and microbial signatures align with risk stratification predictions from the Nath Score, further supporting the role of microbiome alterations in early oesophageal cancer detection.8 Conclusion: This study establishes a direct link between microbiome dysbiosis, immune modulation and epithelial transformation in oesophageal cancer.1–3 The presence of pathogenic microbial signatures correlates with tumour-associated gene expression changes, reinforcing the potential of microbiome-based biomarkers for early diagnosis.6,7 The strong concordance between these findings and the Nath Score risk stratification model further underscores the clinical relevance of integrating microbiome analysis into early cancer detection strategies8. …”
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2602
The Extended Synaptotagmins of <i>Physcomitrium patens</i>
Published 2025-03-01“…In plants, ESYTs have been mainly investigated in <i>A. thaliana</i> and shown to maintain the integrity of the plasma membrane, especially during stress responses like cold acclimatization, mechanical trauma, and salt stress. …”
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2603
Bordetella hinzii Genomic Characteristics and Vaccine Target Discovery
Published 2025-06-01“…This study was aimed at analyzing the pathogenic characteristics of Bordetella hinzii ( B. hinzii ), and elucidating its antibiotic resistance mechanisms, virulence gene distribution, and vaccine development potential. …”
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2604
Chronic intestinal pseudo-obstruction as the same symptom of various basis - review of literature
Published 2024-12-01“…This broad range of causes shows the complexity of this disease. Among pathogens, the most common cause are viruses, especially herpesviruses, what is more bacterial infections and gut dysbiosis must be taken under consideration. …”
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2605
Clinical and psychophysiological analysis of panic attacks in patients with various mental diseases
Published 2011-03-01“…The interdisciplinary approach integrating two (neurological and psychiatric) paradigms was applied to investigate PA. …”
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2606
The transcription factor Ste12 mediates the regulatory role of the Tmk1 MAP kinase in mycoparasitism and vegetative hyphal fusion in the filamentous fungus Trichoderma atroviride.
Published 2014-01-01“…Mycoparasitic species of the fungal genus Trichoderma are potent antagonists able to combat plant pathogenic fungi by direct parasitism. An essential step in this mycoparasitic fungus-fungus interaction is the detection of the fungal host followed by activation of molecular weapons in the mycoparasite by host-derived signals. …”
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2607
Comprehensive safety assessment and therapeutic potential of Pediococcus acidilactici NMCC-B in attenuating arthritis progression.
Published 2025-01-01“…Dysbiosis of gut microbiota and loss of gut-barrier integrity contribute to the development and severity of rheumatoid arthritis (RA). …”
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2608
Antagonism of proteasome inhibitor-induced heme oxygenase-1 expression by PINK1 mutation.
Published 2017-01-01“…PTEN-induced putative kinase 1 (PINK1) is an integral protein in the mitochondrial membrane and maintains mitochondrial fidelity. …”
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2609
Improving Meat Quality, Safety and Sustainability in Monogastric Livestock with Algae Feed Additives
Published 2025-03-01“…Integrating algae (microalgae and seaweeds) into monogastric animal diets presents significant opportunities to improve meat quality, safety, and sustainability. …”
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2610
Biomimetic security model based on immune system control mechanism
Published 2025-04-01“…The model was designed to achieve information learning by mimicking the functions of dendritic immune cells distributed throughout the human body to capture pathogens, the blood vessels that carry information transmission and intercommunication, and the lymphatic system that comprehensively analyzes and processes information and makes decisions. …”
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2611
The Role of Autophagy in Excitotoxicity, Synaptic Mitochondrial Stress and Neurodegeneration
Published 2025-12-01“…Brain and nervous system functions depend upon maintaining the integrity of synaptic structures over the lifetime. …”
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2612
P74 | EXPRESSION OF PISCIDIN, TLR-4, ERK2 AND P-P38 MAPK IN THE ZEBRAFISH GUT EXPOSED TO PCB-126 AND POSSIBLE PROTECTIVE EFFECTS OF GINESTEIN
Published 2025-08-01“…Piscidin is an antimicrobial peptide found in teleost fish, active against pathogens2. TLR4 plays a crucial role in intestinal inflammatory responses induced by PCB 1263. …”
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2613
WINTER WHEAT CROP YIELD AND ITS INFLUENCE ON PROFITABILITY
Published 2023-01-01“…The most representative ones aim at the choice of varieties with genetic characteristics and high production capacity, the application of an optimal level of fertilization and the integrated fight against pathogens, which are key factors that contribute to increasing the productivity and quality of wheat harvests. …”
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2614
A comprehensive review on probiotics and their use in aquaculture: Biological control, efficacy, and safety through the genomics and wet methods
Published 2024-12-01“…This review comprehensively analyzes these diverse aspects, with a particular focus on the potential of studying the interaction between bacterial pathogens and probiotics through these integrated methods.…”
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2615
Factors Affecting Bangladeshi High School Students' Practices of Sanitation and Hygiene
Published 2024-12-01“… Better sanitation and hygiene standards are beneficial for preventing infections, limiting the spread of pathogens, and fostering overall health in educational environments. …”
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2616
Potential of indigenous entomopathogenic fungi diversity in the maize rhizosphere
Published 2024-01-01“…The treatment involves isolating and applying fungi to seeds to observe their pathogenic impact. The DSI, which measures disease intensity, is used to determine whether the fungi are virulent (DSI ≥ 2) or hypovirulent (DSI < 2). …”
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2617
A paradigm shift in simulating affinity maturation to elicit broadly neutralizing antibodies
Published 2025-07-01“…Broadly neutralizing antibodies (bnAbs) offer a promising route to protect against rapidly evolving pathogens such as HIV, influenza, and SARS-CoV-2, yet eliciting them through vaccination remains a significant challenge. …”
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2618
Recent Advances in Natural and Nanoparticle-Based Therapies for Naegleria fowleri Infections
Published 2025-06-01“…These compounds interfere with critical pathogenic mechanisms, including phagocytosis, adhesion, and protease activity highlighting their potential for multi-targeted therapy. …”
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2619
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2620
Outbreak of NDM-5-Producing <i>Proteus mirabilis</i> During the COVID-19 Pandemic in an Argentine Hospital
Published 2025-05-01“…These findings underscore the importance of integrating genomic surveillance into infection control protocols to mitigate the spread of MDR pathogens.…”
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