Ferroptosis and Charcot–Marie–Tooth Disease 1A: Emerging Evidence for a Pathogenic Association by Jacob B. White, Kayla L. Sanchez, Antonio Currais, David Soriano-Castell, Pamela Maher, Salvador Soriano

“…For the first time, we define the pathogenic link between CMT1A and ferroptosis, a form of regulated cell death caused by excessive lipid peroxidation and hindered antioxidant defenses. …”
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Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations. by Federica Mosti, Mariah L Hoye, Carla F Escobar-Tomlienovich, Debra L Silver

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Construction of a pathogenic microorganism detection method based on third-generation nanopore sequencing data by Guoqin Mai, Jiayi Chen, Min Zhang, Wanyue Zhang, Yuting Luo, Ying Dai

“…The similarity, abundance, and matching length of the sequences were integrated to obtain a comprehensive parameter, all_ratio, which can be used to identify pathogenic microorganisms effectively. …”
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Enhancing antimicrobial efficacy: Gum acacia-enriched Lactobacillus consortium against multidrug-resistant pathogens by Jinal Bhola, Rama Bhadekar

“…The escalating challenge of antimicrobial resistance (AMR) has rendered many pathogens impervious to conventional antibiotics, necessitating novel therapeutic approaches. …”
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Deoxynucleosides as promising antimicrobial agents against foodborne pathogens and their applications in food and contact material surfaces by Olajide Sunday Faleye, Jin-Hyung Lee, Jintae Lee

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Development of real-time PCR methods for quality control detection of pathogenic bacteria in cosmetic preparations by Veronica Bolzon, Michela Bulfoni, Alessandro Nencioni, Emanuele Nencioni

“…In conclusion, rt-PCR represents a significant advancement in microbial safety for food and cosmetics, offering a rapid, sensitive, and reliable alternative to conventional methods. By integrating enrichment strategies, rt-PCR ensures higher accuracy in pathogen detection, reinforcing product safety and regulatory compliance in the cosmetics industry.…”
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Multiple Bio-Computational Tools Emerge as Valid Approach in the Assessment of Apolipoproteins Pathogenicity Related Mutations by Giorgia Francesca Saraceno, Erika Cione

“…<b>Results:</b> We identified seventeen SNPs in total, twelve for ApoB, one for ApoC2, one for ApoC3, and three for ApoE, representing 70%, 6%, 6% and 18%, respectively. The pathogenity of ApoE, was highlighted in two SNPs the rs769452 with amino acid replacement L46P, and rs769455 with amino acid replacement R163C. …”
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Bacterial Pathogens and Antibiotic Resistance in Bloodstream Infections in Tunisia: A 13-Year Trend Analysis by Lamia Kanzari, Sana Ferjani, Khaoula Meftah, Mariem Zribi, Sonda Mezghani, Asma Ferjani, Yosra Chebbi, Manel Hamdoun, Hajer Rhim, Yosr Kadri, Siwar Frigui, Emna Mhiri, Asma Ghariani, Nour Ben Ayed, Faouzia Mahjoubi, Yomna Ben Lamine, Salma Kaoual, Basma Mnif, Habiba Naija, Manel Marzouk, Sarra Dhraief, Hela Karray, Jaya Prasad Tripathy, Bobson Derrick Fofanah, Safa Bouwazra, Hajer Battikh, Ramzi Ouhichi, Lamia Thabet, Jalel Boukadida, Farouk Barguellil, Sophia Besbes, Leila Slim, Maha Mastouri, Olfa Bahri, Wafa Achour, Adnene Hammami, Hanen Smaoui, Ilhem Boutiba-Ben Boubaker

“…The antimicrobial resistance (AMR) surveillance network has been monitoring bloodstream bacterial pathogens and their resistance since 1999 in Tunisia. …”
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A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria by Peter Lasch, Wolfgang Beyer, Alejandra Bosch, Rainer Borriss, Michal Drevinek, Susann Dupke, Monika Ehling-Schulz, Xuewen Gao, Roland Grunow, Daniela Jacob, Silke R. Klee, Armand Paauw, Jörg Rau, Andy Schneider, Holger C. Scholz, Maren Stämmler, Le Thi Thanh Tam, Herbert Tomaso, Guido Werner, Joerg Doellinger

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E.PathDash, pathway activation analysis of publicly available pathogen gene expression data by Lily Taub, Thomas H. Hampton, Sharanya Sarkar, Georgia Doing, Samuel L. Neff, Carson E. Finger, Kiyoshi Ferreira Fukutani, Bruce A. Stanton

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Exploring the Diversity of Some Microorganisms from Lake Al-Asfar, KSA: The Good, the Bad, and the Pathogenic by Fatimah Al Tammar, Nermin El Semary, Munirah F. Aldayel, Duaa Althumairy, Gowhara Alfayad

“…The lake is a habitat to different microbial species that play important ecological roles, some of which are good, and some are bad and even pathogenic. In a previous investigation, algal-bacteria consortia have proven to be beneficial in bioremediating heavy metals and hydrocarbons in Lake Al-Asfar. …”
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Vaccination is an integral strategy to combat antimicrobial resistance. by Liam P Mullins, Emily Mason, Kaitlin Winter, Manish Sadarangani

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Precision-engineered mRNA vaccines: antigen design, structural optimization, and programmable delivery for emerging pathogens by Yanyu Zhang, Junchi Li, Zihan Wang, Yu Kuang, Songli Li, Xiaojia Wang

“…Finally, we address the current challenges and future prospects of mRNA vaccine technology, aiming to inform and accelerate the development of next-generation vaccines against emerging pathogens through the integration of these innovations.…”
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Evolutionarily stable gene clusters shed light on the common grounds of pathogenicity in the Acinetobacter calcoaceticus-baumannii complex. by Bardya Djahanschiri, Gisela Di Venanzio, Jesus S Distel, Jennifer Breisch, Marius Alfred Dieckmann, Alexander Goesmann, Beate Averhoff, Stephan Göttig, Gottfried Wilharm, Mario F Feldman, Ingo Ebersberger

“…Aiding the urgent demand for novel therapeutic targets, comparative genomics studies between pathogens and their apathogenic relatives shed light on the genetic basis of human-pathogen interaction. …”
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vPro-MS enables identification of human-pathogenic viruses from patient samples by untargeted proteomics by Marica Grossegesse, Fabian Horn, Andreas Kurth, Peter Lasch, Andreas Nitsche, Joerg Doellinger

“…In this study, we introduce proteomics as a complementary approach for the untargeted identification of human-pathogenic viruses from patient samples. The viral proteomics workflow (vPro-MS) is based on an in-silico derived peptide library covering the human virome in UniProtKB (331 viruses, 20,386 genomes, 121,977 peptides). …”
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<i>Neopestalotiopsis</i> spp.: A Threat to Strawberry Production and Management by José Guadalupe Ávila-Hernández, Claudia Geraldine León-Ramírez, Ma. del Rosario Abraham-Juárez, Bertha Tlapal-Bolaños, Víctor Olalde-Portugal, John Paul Délano-Frier, Agustino Martínez-Antonio, Pedro Aguilar-Zárate

“…<i>Neopestalotiopsis</i> spp. are emerging fungal pathogens associated with leaf spot, fruit rot, crown rot, and root rot in strawberries. …”
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Enhancing Healthcare Preparedness: Lessons from a Tabletop Exercise on Highly Pathogenic Avian Influenza (HPAI) by Priya Dhagat, Joshua Coan, Ayanava Ganguly, Cole Puetz, David Silvestri, Syra Madad

“…The New York City Health + Hospitals System-Wide Special Pathogens Program conducted an innovative and multidisciplinary tabletop exercise involving escalating scenarios of highly pathogenic avian influenza (HPAI) H5N1 in 2023. …”
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Research progress on the application of RPA-CRISPR/Cas12a in the rapid visual detection of pathogenic microorganisms by Tuo Ji, Tuo Ji, Tuo Ji, Xin Fang, Yuzhi Gao, Yuzhi Gao, Yuzhi Gao, Kun Yu, Kun Yu, Kun Yu, Xuzhu Gao, Xuzhu Gao, Xuzhu Gao

“…In an increasingly complex global public health landscape, the continuous emergence of novel pathogens and the growing problem of antibiotic resistance highlight the urgent need for rapid, efficient, and precise detection technologies for pathogenic microorganisms. …”
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Establishing a European wastewater pathogen monitoring network employing aviation samples: a proof of concept by Robert Morfino, Bernd Manfred Gawlik, Simona Tavazzi, Angela Tessarolo, Ana Burgos Gutierrez, Nita K. Madhav, Jasmine Grimsley, Amy Schierhorn, Andrew Franklin, Marta Vargha, Andrew Engeli, Mitchell Wolfe

“…The authors suggest establishing "Super Sites" in key locations, particularly major transportation hubs like airports, to serve as focal points for wastewater-based pathogen surveillance. The European Commission has identified over 20 candidate Super Sites and supports their integration into a Global Wastewater Sentinel System. …”
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A three-component signaling system plays multiple roles in the pathogenicity of Xanthomonas citri subsp. citri by Xiaoyan Zhao, Xiaoyun Chen, Junjie Lei, Jiaying Feng, Yunyang Dong, Yu Shi, Linghui Xu, Junxia Wang

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