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Rapid Development of Small Rodent Animal Models for Infectious Disease Research Through Vectorized Receptor Molecule Expression
Published 2024-11-01“…The emergence and re-emergence of pathogens with pandemic potential has been a persistent issue throughout history. …”
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2405
Free Radical Oxidation Induced by Iron Metabolism Disorder in Femoral and Pelvic Fractures and Potential for Its Correction
Published 2016-02-01“…Objective: To determine the pathogenic significance of iron ions in the activation of free radical oxidation in trau matic disease and valuate the efficacy of Desferal in the complex therapy of patients with femoral and pelvic fractions.Materials and methods. …”
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RELATIONSHIP BETWEEN PERIODONTAL DISEASES AND MENTAL HEALTH: A NARRATIVE REVIEW
Published 2025-05-01“…Chronic stress and depression can result in general dysregulation of the immune system, of both cellular and humoral pathways, which may contribute to pathogenic infection and concomitant periodontal tissue destruction. …”
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Alterations and resilience of intestinal microbiota to increased water temperature are accompanied by the recovery of immune function in Nile tilapia
Published 2025-02-01“…After prolonged coevolution, the intestinal microbiota has become an integral part of fish and plays a pivotal role in immunity and metabolism. …”
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Comparative Analysis of Deep Learning-Based Feature Extraction and Traditional Classification Approaches for Tomato Disease Detection
Published 2025-06-01“…Tomato, being one of the most widely consumed agricultural products globally and highly susceptible to a variety of fungal, bacterial, and viral pathogens, remains a prominent focus in disease detection research. …”
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BLIS Fingerprinting as a Tool to Investigate the Distribution and Significance of Bacteriocin Production and Immunity in <i>Streptococcus pyogenes</i> and <i>Streptococcus salivari...
Published 2025-05-01“…The potential for harnessing bacteriocin-producing streptococci in antimicrobial interventions, particularly in combating antibiotic-resistant pathogens, underscores the translational relevance of these findings. …”
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Regulation and Function of the cGAS-STING Pathway: Mechanisms, Post-Translational Modifications, and Therapeutic Potential in Immunotherapy
Published 2025-03-01“…Normally, the immune system recognizes and defends against pathogens like bacteria and viruses. The cGAS-STING pathway, activated by pattern-recognition receptors (PRRs), plays a key role in autoimmune responses. …”
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Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation
Published 2025-06-01“…DN is associated with gut dysbiosis—characterized by reduced microbial diversity, depletion of beneficial short-chain fatty acid (SCFA)-producing bacteria, and proliferation of opportunistic pathogens. This dysbiosis impairs gut barrier integrity, fostering systemic inflammation and the accumulation of uremic toxins like indoxyl sulfate. …”
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Increased circulating platelet-derived extracellular vesicles in severe COVID-19 disease
Published 2024-12-01Get full text
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Inflammatory cytokine interleukin-18 prevents murine miscarriage by inducing appropriate inflammation
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CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulatin...
Published 2025-08-01“…NGS identified class 5 pathogenic variants in 8 patients with HA (F8, including intron 22 inversion) and in 2 with HB (F9), and class 4 likely pathogenic variants in 3 patients (F8 [n=2] and, F11 [n=1]). …”
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ALX1‐related frontonasal dysplasia results from defective neural crest cell development and migration
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Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria
Published 2025-07-01“…Genomic characterization links npmA2 to a composite transposon, Tn7734, which is integrated within a previously uncharacterized Integrative and Conjugative Element (ICE) Tn7740, present in both npmA2-carrying C. difficile and E. faecium clinical isolates. …”
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Neuroinflammation and Natural Antidepressants: Balancing Fire with Flora
Published 2025-05-01“…Additional research into improved dosage, pharmacokinetics, long-term safety, and integrative therapy approaches is essential. Using phytotherapeutics could considerably improve holistic and customized depression care, encouraging new research routes in integrative neuroscience and clinical psychiatry.…”
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Hyphal penetration is the major pathway of translocation of Candida albicans across the blood-cerebrospinal fluid barrier
Published 2025-04-01“…Candida albicans is one of the leading pathogens in this setting, and may affect the central nervous system (CNS), which is an extremely severe form of the infection. …”
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