The use of cytokines in the treatment of cornea inflammatory and dystrophic diseases (review) by M. S. Denisko, O. I. Krivosheina

“…Cytokines are unique biologically active substances that form the system of regulation of basic body functions that simultaneously with the nervous and endocrine systems maintain homeostasis under adverse conditions – the introduction of pathogens or violation of the integrity of tissues. …”
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Generation of a human induced pluripotent stem cell lines (UKJi003-A) from a patient with Fabry disease and healthy donor (UKJi004-A) by Mohamed M. Bekhite, Sascha Hübner, Tom Kretzschmar, Claudia Backsch, Anja Weise, Elisabeth Klein, Jürgen Bogoviku, Julian Westphal, P. Christian Schulze

“…Fabry disease (FD, OMIM #301500) is a rare metabolic disorder, X-linked glycosphingolipidosis that is characterized by pathogenic mutations in the GLA (Galactosidase Alpha) gene (OMIM *300644) that result in reduced α-galactosidase A (α-GAL) activity and accumulation of globotriaosylceramide (Gb3) in tissues and organs. …”
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Unveiling a rare genetic aberration: A case study of Prader-Willi syndrome (PWS) with atypical 15q11.2-q13.3 deletion by Senthilraja Ramalingam, Srividya Ganapathy, Jayaswathi Kanchepalli, Vani Jayaraj, Mani Mariyappa

“…Whole blood sample of the patient was analysed to reveal a pathogenic deletion spanning the region 15q11.2–q13.3; a rare and extended deletion involving breakpoints BP1 to BP5. …”
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Investigation of the inhibitory properties of azo-dyes on chorismate synthase from Paracoccidioides brasiliensis by Katharina Fuchs, Massimo G. Totaro, Marina Toplak, Aleksandar Bijelic, Peter Macheroux

“…Thus, our study is the first to integrate structural and computational methods to guide future efforts towards designing the next generation of CS inhibitors.…”
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Emerging Trends of Immunosensors Development for Detection of Food Toxins by Fabien Nsanzabera, Aimable Mwiseneza, Evangeline Irakoze, Jean Bosco Nsengiyumva, Barthazar Nduwayezu, Alexis Manishimwe, Fabien Nkurikiyimana

“…The present study highlights the ongoing threat of foodborne illnesses to public health, primarily caused by bacterial pathogens. Despite advancements in conventional microbiological testing techniques, which are sensitive but time-consuming, challenges remain in ensuring timely detection of contaminants throughout the food supply chain. …”
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Genetic neurocognitive profile of autism unveiled with gene transcription by Yingxing Zhang, Fangfang Li, Hongli Wu, Wei Du, Jianhua Shu, Anqing Wang, Chunsheng Xu, Chuanfu Li, Ya Wang, Sheng Hu

“…Applying the principal component analysis to the Neurosynth database, we established neurocognitive profiles to characterize the phenotypic heterogeneity of ASD, revealing a cortical hierarchical axis that separates the temporal cortex from other networks. By integrating neurocognitive profiles with transcriptomic data, we found that gene sets shaping the patterns of neurocognitive profiles are enriched in ASD-related biological processes and ASD pathogenic risk. …”
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Global distribution and predictive modeling of Vibrio vulnificus abundance by David J. Riedinger, Christiane Hassenrück, Daniel Herlemann, Matthias Labrenz

“…Abstract The proliferation of the potentially pathogenic bacterium Vibrio vulnificus due to climate change poses a growing public health threat worldwide. …”
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Recent Advances in Biopesticide Research and Development with a Focus on Microbials [version 2; peer review: 2 approved] by Dennis Ndolo, Jing Ge, Debbie Muir, Lawrence Malinga, Kahsay Tadesse Mawcha

“…Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. …”
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The Intersection of the Upper Gastrointestinal Microbiome and Oesophageal Cancer: A Review of Pathways and Therapeutic Insights by Jenny Bui, Katelyn Ward, Rishindra Reddy

“…Most research to date has focused on colorectal cancer, demonstrating these complex relationships. Pathogenic bacteria exacerbate the dysregulation processes through mechanisms including pro-inflammatory cytokine release, immune evasion, and biofilm formation. …”
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Healthcare-Associated Infections: Modern Doctrine of Prophylaxis. Part II. Basic Concept by E. B. Brusina, L. P. Zuyeva, O. V. Kovalishena, V. L. Stasenko, I. V. Feldblium, N. I. Briko, V. G. Akimkin

“…Epidemiological safety is an integral part of ensuring the quality and safety of medical care.…”
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The Importance of Studying Infectious and Parasitic Diseases of Wild Animals in the Amazon Biome with a Focus on One Health by Felipe Masiero Salvarani, Hanna Gabriela da Silva Oliveira, Letícia Yasmin Silva Correa, Aline Alessandra Lima Soares, Brenda Cabral Ferreira

“…This narrative review examines key pathogens, including viruses, bacteria, and parasites, that pose significant risks to wildlife conservation and public health. …”
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Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis by Filippo Vascon, Sofia De Felice, Matteo Gasparotto, Stefan T. Huber, Claudio Catalano, Monica Chinellato, Riccardo Mezzetti, Alessandro Grinzato, Francesco Filippini, Lorenzo Maso, Arjen J. Jakobi, Laura Cendron

“…Summary: Antimicrobial resistance poses a severe threat to human health and Pseudomonas aeruginosa stands out among the pathogens responsible for this emergency. The SOS response to DNA damage is crucial in bacterial evolution, influencing resistance development and adaptability in challenging environments, especially under antibiotic exposure. …”
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Current Applications and the Future of Phage Therapy for Periprosthetic Joint Infections by Arian Ocean Abedi, Armita Armina Abedi, Tristan Ferry, Mustafa Citak

“…Phage therapy, which utilizes bacteriophages to target bacterial pathogens, offers a promising supplement to traditional antimicrobial methods. …”
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Recent Advances in Biopesticide Research and Development with a Focus on Microbials [version 5; peer review: 3 approved, 1 approved with reservations] by Dennis Ndolo, Jing Ge, Debbie Muir, Lawrence Malinga, Kahsay Tadesse Mawcha

“…Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. …”
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Recent Advances in Biopesticide Research and Development with a Focus on Microbials [version 4; peer review: 3 approved, 1 approved with reservations] by Dennis Ndolo, Jing Ge, Debbie Muir, Lawrence Malinga, Kahsay Tadesse Mawcha

“…Biopesticides are pest control products derived from natural sources such as microbes, macro-organisms (insects and pathogens), plant extracts, and certain minerals. Many biopesticides are considered environmentally safe and can complement or substitute conventional chemical pesticides. …”
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Insights into the unique roles of extracellular vesicles for gut health modulation: Mechanisms, challenges, and perspectives by Qiming Wu, Juntao Kan, Caili Fu, Xin Liu, Zhengying Cui, Sixu Wang, Yi Le, Zhanming Li, Qin Liu, Yuyu Zhang, Jun Du

“…This review delves into the roles and mechanisms of EVs from diverse sources in regulating gut health, focusing on their contributions to maintaining epithelial barrier integrity, facilitating tissue healing, eliciting immune responses, controlling pathogens, and shaping microbiota. …”
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Can Bisphenols Alter the Inflammation Process? by Denis Bazany, Hana Greifova, Lucia Zuscikova, Katarina Tokarova, Tomas Jambor, Anton Kovacik, Norbert Lukac

“…From this point of view, it is very important to clarify their influence on innate immune reactions, which protect the integrity of the body against the action of various pathogens on a daily basis. …”
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Targeting myeloid cells for hematological malignancies: the present and future by Zihui Guan, Zhengqi Zhang, Kaiyan Wang, Shukai Qiao, Teng Ma, Lina Wu

“…This review explores the unique characteristics and pathogenic mechanisms of myeloid blasts, the immunosuppressive roles of myeloid cells, and their complex interactions within the TME. …”
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The role of HERV envelope protein in ovarian cancer by Jianhao Zhang, Dongyu Sun, Yuqing Zhan, Qing Gao, Chenxuan Bao, Huayuan Xiang, Yuxuan Shen, Qianqian Gao, Mengyu Zhang, Jianjun Wang, Lingxiang Mao

“…Human endogenous retroviruses (HERVs) are a remnant of repeated exogenous retroviral infections in human ancestors, which have been integrated into germline cells and proliferated through retrotransposition, recombination, and reinfection. …”
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Unleashing the potential of high-throughput sequencing for plant virus and viroid detection in Mexico by Carolina Pacheco-Dorantes, Juan Manuel Tovar-Pedraza, Daniel Leobardo Ochoa-Martínez, Ramiro González-Garza, Alfredo Diaz-Lara

“…This technology has contributed to identifying previously neglected pathogens affecting key crops such as corn, beans, and tomato. …”
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