Clinico-radiological characteristics and lethality of HIV-tuberculosis coinfection in the Infectiology ward of the Libreville University Hospital, Gabon by Michele Marion Ntsame Owono, Charleine Manomba Boulingui, Magalie Essomeyo Ngue Mebale, Marielle Karine Bouyou Akotet

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LDL cholesterolemia as a novel risk factor for radiographic progression of rheumatoid arthritis: a single-center prospective study. by Yune-Jung Park, Chul-Soo Cho, Paul Emery, Wan-Uk Kim

“…Evidence is emerging that there might be a pathogenic interaction among inflammation, dyslipidemia, and adipokines. …”
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Comparison of genotypes and phenotypes for von Willebrand factor gene variants using Japanese genome database by Takafumi Akimoto, Hiroshi Inaba, Soichi Ogishima, Kazuki Kumada, Ayano Mitsuhashi, Ryui Miyashita, Tomoko Yamaguchi, Masato Bingo, Yushi Chikasawa, Keiko Shinozawa, Takeshi Hagiwara, Kagehiro Amano, Eiichi N. Kodama, Ei Kinai

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A novel silver-ruthenium-based antimicrobial kills Gram-negative bacteria through oxidative stress-induced macromolecular damage by Patrick Ofori Tawiah, Luca Finn Gaessler, Greg M. Anderson, Emmanuel Parkay Oladokun, Jan-Ulrik Dahl

“…ExPEC strains appear to be more resistant to the proteotoxic effects of AGXX compared to non-pathogenic E. coli, indicating improved defense capabilities of the uropathogen. …”
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Metagenomic analysis of antibiotic resistance across the wastewater process by Stephanie Pillay, Ramin Shirali Hossein Zade, Paul van Lent, David Calderón-Franco, Thomas Abeel

“…ESKAPE pathogens, including Klebsiella pneumoniae and Enterobacter species, were identified in the effluent with abundances over 1%. …”
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Probiotics Alleviated Nonalcoholic Fatty Liver Disease in High-Fat Diet-Fed Rats via Gut Microbiota/FXR/FGF15 Signaling Pathway by Minmin Luo, Junbin Yan, Liyan Wu, Jinting Wu, Zheng Chen, Jianping Jiang, Zhiyun Chen, Beihui He

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Super-resolution of nodal and paranodal disruption in anti-pan-neurofascin-associated autoimmune nodopathy by Vinicius da Cruz Neris Geßner, Vinicius da Cruz Neris Geßner, Janis Theobald Linke, Janis Theobald Linke, Thomas-Otavio Peulen, Luise Appeltshauser, Claudia Sommer, Dirk Brämer, Christian Geis, Katrin Gertrud Heinze, Kathrin Doppler

“…Understanding the impact of autoantibody binding on protein assembly is crucial for gaining insights into the pathogenicity of different autoantibodies. We investigated nodal, paranodal, and cytoskeletal axonal proteins in teased fibers from a sural nerve biopsy of a patient with anti-pan-neurofascin autoantibodies. …”
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Unveiling the Therapeutic Potential: Targeting Fibroblast-like Synoviocytes in Rheumatoid Arthritis by Siran Yue, Junyu Fan, Duoli Xie, Chunhao Cao, Zhuqian Wang, Jie Huang, Fang Qiu, Xu Yang, Dongyi He, Aiping Lu, Chao Liang

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Case report: Deciphering the clinical significance of a novel partial BRCA1 exon 10 duplication in a patient with triple-negative breast cancer by Alice Faversani, Debora Manuelli, Davide Barteselli, Giulia Melloni, Carlo Santaniello, Luigi Corsaro, Luigi Corsaro, Davide Sacco, Davide Sacco, Davide Clerici, Laura Gargiulo, Fulvio Ferrara, Lucy Costantino

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Antiviral nanomedicine: Advantages, mechanisms and advanced therapies by Yicheng Pu, Chuanda Zhu, Jun Liao, Lidong Gong, Yijuan Wu, Shunquan Liu, Hongjun Wang, Qiang Zhang, Zhiqiang Lin

“…The emergence of novel viral pathogens and the limitations of conventional antiviral therapies necessitate innovative strategies to combat persistent and pandemic threats. …”
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Sphingolipids and Brain Resident Macrophages in Neuroinflammation: An Emerging Aspect of Nervous System Pathology by Emma Assi, Denise Cazzato, Clara De Palma, Cristiana Perrotta, Emilio Clementi, Davide Cervia

“…Modulations in microglia phenotypes may contribute to pathogenic forms of inflammation. Since defects in macrophage/microglia activity contribute to neurodegenerative diseases, it will be essential to systematically identify the components of the microglial cell response that contribute to disease progression. …”
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Nanomedicine and Its Role in Surgical Wound Infections: A Practical Approach by Malak Bentaleb, Mohammed Abdulrahman, Marcelo A. F. Ribeiro Jr

“…With the rise of antibiotic-resistant pathogens, it is crucial to develop new innovative wound materials to manage surgical wound infections using methods that facilitate drug delivery agents and rely on materials other than antimicrobials. …”
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Cultivating complexity: Advancements in establishing in vitro models for the mucus‐adhering gut microbiota by Marco Calvigioni, Diletta Mazzantini, Francesco Celandroni, Giovanni Vozzi, Emilia Ghelardi

“…Mucus‐adhering bacteria play crucial roles in preserving barrier integrity, epithelial permeability and mucus architecture, as well as in the colonization resistance against pathogens. …”
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Harnessing Electrostatic Forces: A Review of Bees as Bioindicators for Particulate Matter Detection by Simone Meacci, Lorenzo Corsi, Eleonora Santecchia, Sara Ruschioni

“…Additionally, the study evaluates the adhesion efficiency of pollutants, including heavy metals, microplastics, nanoplastics, pathogens, pesticides, radionuclides, and volatile organic compounds. …”
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Overview of hirsutella-like anamorphs in Ophiocordyceps (Sordariomycetes, Ophiocordycipitaceae): introducing two new species and one new record from China by Shi-Wen Xie, De-Ping Wei, Jun-Zhi Qiu, Xing-Can Peng, Ji-Chuan Kang, Zhang-Jiang He, Zeng-Zhi Li, Chun-Ru Li, Shi-Ke Huang, Xian Zhang, Zhong-Liang Liu, Jing Bu, Nalin N. Wijayawardene, Ting-Chi Wen

“…Hirsutella radiata), a new combination, exhibits a pathogenic association with a fly, and it is reported as a new geographic record from China, based on integrated morphological and molecular analyses. …”
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IL-17: Balancing Protective Immunity and Pathogenesis by Lu Sun, Lufei Wang, Bethany B. Moore, Shaoping Zhang, Peng Xiao, Ann M. Decker, Hom-Lay Wang

“…While substantial progress has implicated unrestrained IL-17 in a variety of infectious diseases or autoimmune conditions, IL-17 plays an important role in protecting the host against pathogens and maintaining physiological homeostasis. …”
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Research advances in understanding the role of interleukin-22 in renal disease by Zhao Dan, Zhu Xiao-yu, Jiang Li-li, Wei Xue-jiao, Long Meng-tuan, Jin Die, Miao Chang-xiu, Du Yu-jun

“…Interleukin 22（IL-22），a member of IL-10 cytokine superfamily，is dominantly produced by innate lymphoid cells and CD4+ T helper subtypes such as Th17 and Th22 cells.And interleukin-22 receptor （IL-22R） is a dimer composed of IL-22R1 and IL-10R2 subunit.IL-22 plays a role by conjugating with IL-22R.Recently IL-22 has gained a lot of interest for its unique functions in maintaining and regaining epithelial integrity.However，IL-22 may play a protective or pathogenic role in the occurrence and development of inflammatory and autoimmune diseases.This review summarized the latest researches of IL-22 in renal injury-related diseases.…”
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Natural Solutions to Antimicrobial Resistance: The Role of Essential Oils in Poultry Meat Preservation with Focus on Gram-Negative Bacteria by Zorana Kovačević, Ivana Čabarkapa, Ljubiša Šarić, Marko Pajić, Dragana Tomanić, Bojana Kokić, Dragana D. Božić

“…The genetic transfer of resistance elements between poultry MDR bacteria and human pathogens further exacerbates the AMR crisis and highlights the urgent need for action. …”
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Emerging Link between Alzheimer’s Disease and Homeostatic Synaptic Plasticity by Sung-Soo Jang, Hee Jung Chung

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Role of trefoil factors in maintaining gut health in food animals by Yewande O. Fasina, Temitayo O. Obanla, Deji A. Ekunseitan, George Dosu, Joseph Richardson, Oluwabunmi O. Apalowo

“…These protective properties, suggest that dietary manipulation strategies targeted at enhancing the expression and synthesis of TFF peptides at optimal levels in the GIT epithelium, may constitute a plausible alternative strategy to the use of in-feed antibiotic growth promoters to maintain epithelial integrity and promote resistance to enteric pathogens. …”
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