Building Pathogen Genomic Sequencing Capacity in Africa: Centre for Epidemic Response and Innovation Fellowship by Eric Agboli, Molalegne Bitew, Christian N. Malaka, Tiangay M. P. S. Kallon, Alhaji M. S. Jalloh, Baron Yankonde, Doreen M. Shempela, Jay F. M. Sikalima, Mutale Joseph, Mpanga Kasonde, Feleke M. Demeke, Ayemfouo F. I. Valdese, Lele B. Grace, Godwe Célestin, Ana Papkiauri, Sado Y. F. Berlange, Janet Majanja, Vane K. Omwenga, Evalyne N. Wambugu, Samuel M. Kariuki, Alex A. Mwanyongo, Ubheeram Jaykissen, Caroline Abanto Alvarez, Seyni Ndiaye, Benjamin Moswane, Ester K. Adamson, Mariam Makange, Luka Sote, Ibrahimm Mugerwa, Julius Sseruyange, Patrick Semanda, Brian A. Kagurusi, Abdualmoniem O. Musa, Kourush Fassihi, Lavanya Singh, Monika Moir

“…Adaptation and miniaturisation of protocols to detect other pathogens is a great enhancement over the traditional method of using a single protocol for a pathogen. …”
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Ancestral and recent bursts of transposition shaped the massive genomes of plant pathogenic rust fungi by Emma Corre, Emmanuelle Morin, Sébastien Duplessis, Cecile Lorrain

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MP3: a software tool for the prediction of pathogenic proteins in genomic and metagenomic data. by Ankit Gupta, Rohan Kapil, Darshan B Dhakan, Vineet K Sharma

“…MP3 is developed using an integrated Support Vector Machine (SVM) and Hidden Markov Model (HMM) approach to carry out highly fast, sensitive and accurate prediction of pathogenic proteins. …”
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Broad-spectrum antimicrobial activity and in vivo efficacy of SK1260 against bacterial pathogens by Sridhar Kavela, Swetha Kakkerla, Murali Krishna Thupurani

“…Peptide treatment restored normal tissue architecture and showed efficacy equivalent to standard antibiotic therapy.DiscussionThe study establishes SK1260 as a promising broad-spectrum antimicrobial agent with efficacy against drug-resistant pathogens. Its ability to reduce bacterial burden and protect tissue integrity in vivo highlights its therapeutic potential. …”
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Application of Hyperspectral Imaging for Early Detection of Pathogen-Induced Stress in Cabbage as Case Study by Magdalena Szechyńska-Hebda, Ryszard Hołownicki, Grzegorz Doruchowski, Konrad Sas, Joanna Puławska, Anna Jarecka-Boncela, Magdalena Ptaszek, Agnieszka Włodarek

“…The findings underscore the importance of targeting specific spectral ranges for early pathogen detection. By integrating these techniques with machine learning, this research demonstrates their applicability in advancing precision agriculture, improving disease management, and promoting sustainable production systems.…”
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Temporal dynamics of walnut phyllosphere microbiota under synergistic pathogen exposure and environmental perturbation by Shiwei Wang, Yu Tan, Qing Luo, Xinmei Fang, Hanmingyue Zhu, Shuying Li, Yujue Zhou, Tianhui Zhu, Tianhui Zhu

“…IntroductionPhyllosphere-associated microbes directly influence plant-pathogen interactions, and the external environment and the plant shape the phyllosphere microbiome.MethodsIn this study, we integrated 16S rRNA and ITS high-throughput sequencing to systematically investigate changes in the phyllosphere microbiome between symptomatic and asymptomatic walnut leaves affected by spot disease, with consideration of phenological stage progression. …”
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Immune dysregulation in ulcerative colitis: pathogenic mechanisms and therapeutic strategies of traditional Chinese medicine by Xudong Tang, Yilin Huang, Ying Zhu, Yin Xu

“…This article reviews the pathogenic mechanisms underlying immune dysregulation in UC and the advances in research on TCM’s role in immune regulation, anti-inflammatory repair, and flora modulation, encompassing the mechanisms of action of individual active ingredients and classic TCM compound formulas. …”
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Posterior segment findings in a patient with a CDHR1 biallelic pathogenic variant by Yusuf Kemal Durlu, Sezin Canbek

“…Purpose: To report the posterior segment findings in a case with a biallelic CDHR1 frameshift pathogenic variant at chromosome 10 c.616del exon7 p.…”
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Predominant Pathogens in Sternal Wound Infections Following Cardiac Surgery: A Systematic Review by Netty Suharty, Muhammad Riendra, Aulia Rahman, Heka Widya Putri, Ardiansyah Ardiansyah

“…Results: A total of 10,596 references were discovered and 8 articles were chosen for the integrative review based on duplication, relevance and inclusion/exclusion criteria. …”
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Highly pathogenic avian influenza: pandemic preparedness for a scenario of high lethality with no vaccines by Cristina Possas, Ernesto T. A. Marques, Ernesto T. A. Marques, Alessandra Oliveira, Suzanne Schumacher, Marilda M. Siqueira, John McCauley, Adelaide Antunes, Adelaide Antunes, Akira Homma

“…Highly Pathogenic Avian Influenza (HPAI) viruses, particularly H5N1 and H7N9, have long been considered potential pandemic threats, despite the absence of sustained human-to-human transmission. …”
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Hemotropic pathogens in aborted fetuses of domestic ruminants: transplacental transmission and implications for reproductive loss by Daria Jurković Žilić, Šimun Naletilić, Željko Mihaljević, Ema Gagović, Silvio Špičić, Irena Reil, Sanja Duvnjak, Maja Zdelar Tuk, Adnan Hodžić, Relja Beck

“…The detection of species-specific patterns and the unexpected identification of protozoan species typically associated with canines highlight complex epidemiological dynamics.ConclusionVertical transmission of the detected pathogens may play a role in abortion in endemic regions and should be integrated into differential diagnostic protocols for reproductive failure investigations.…”
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Exploration of drug repurposing for Mpox outbreaks targeting gene signatures and host-pathogen interactions by Saber Imani, Sargol Aminnezhad, Moslem Alikarami, Zahra Abedi, Iman Samei Mosleh, Mazaher Maghsoudloo, Zahra Taheri

“…Subtype-specific host-pathogen protein-protein interaction networks were constructed, and key modules from the HPI and WGCNA were integrated to identify significant host proteins. …”
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NLRP3 Inflammasome-Mediated Pyroptosis in Diabetic Nephropathy: Pathogenic Mechanisms and Therapeutic Targets by Chen Y, Chen R, Ji X, Zeng Z, Guan C

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Race, ethnicity and risk for colonisation and infection with key bacterial pathogens: a scoping review by Courtney W Chan, Nanguneri Nirmala, Esther E Avendano, Sarah Addison Blackmon, Rebecca A Morin, Sweta Balaji, Lily McNulty, Samson Alemu Argaw, Shira Doron, Maya L Nadimpalli

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Pathogenicity potential of enterococci isolated from a Veterinary Biological Isolation and Containment Unit by Catarina Geraldes, Catarina Geraldes, Catarina Araújo, Catarina Araújo, Ana Catarina Pinheiro, Ana Catarina Pinheiro, Mónica Afonso, Mónica Afonso, Sandra Carapeto, Sandra Carapeto, Cláudia Verdial, Eva Cunha, Eva Cunha, Raquel Abreu, Raquel Abreu, Luís Tavares, Luís Tavares, Lélia Chambel, Solange Gil, Solange Gil, Solange Gil, Manuela Oliveira, Manuela Oliveira, Manuela Oliveira

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The virulence regulator AbsR in avian pathogenic Escherichia coli has pleiotropic effects on bacterial physiology by Dongfang Zhao, Haobo Zhang, Xinyang Zhang, Fengwei Jiang, Yijing Li, Wentong Cai, Ganwu Li

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Fungal Species Associated with Tuber Rot of Foshou Yam (<i>Dioscorea esculenta</i>) in China by Haifeng Liu, Aye Aye Htun, Sein Lai Lai Aung, Hyunkyu Sang, Jianxin Deng, Yaqun Tao

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Role of infectious agents in cancer pathogenesis and therapy by Ezichi F. Ofoezie, Chinwendu A. Ogbonna, Sandra C. Olisakwe, Chioma J. Anunobi, Ezinne T. George, Simeon Babarinde, Chidera G. Chukwuemeka, Uzochukwu E. Ogbonna, Chibuzo C. Amafili, Chibuzo V. Alisigwe, Onyinyechi J. Omaba, Henry N. Ogbonna

“…This review delves into the complex mechanisms pathogens drive oncogenesis, emphasizing chronic inflammation, immune evasion, genetic integration, and epigenetic alterations. …”
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The role of integration in oncogenic progression of HPV-associated cancers. by Alison A McBride, Alix Warburton

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Vers une approche individu-centrée pour modéliser et simuler l’expression spatiale d’une maladie transmissible : la peste à Madagascar by Dominique Badariotti, Arnaud Banos, Vincent Laperrière

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