PGRN protects against serum deprivation-induced cell death by promoting the ROS scavenger system in cervical cancer by Tingting Feng, Xiaoying Xu, Xiao Wang, Wei Tang, Yi Lu

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The critical involvement of monocytes/macrophages in the pathogenesis of primary Sjögren's syndrome: New evidence from Mendelian randomization and single-cell sequencing by Yimei Ding, Xue Luan, Jiaqi Hou

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Methicillin-resistant Staphylococcus epidermidis knee prosthetic infection treatment with two-stage revision and fosfomycin–rifampin combination therapy: a case report by Giulio Maria Marcheggiani Muccioli, Eleonora Zamparini, Alberto Fogacci, Andrea Grechi, Federico Pea, Pierluigi Viale, Stefano Zaffagnini

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Baicalin promotes β-1,3-glucan exposure in Candida albicans and enhances macrophage response by Yiyuan Pan, Zhaoling Shi, Yadong Wang, Feng Chen, Feng Chen, Feng Chen, Yue Yang, Yue Yang, Yue Yang, Kelong Ma, Kelong Ma, Kelong Ma, Wenqian Li, Wenqian Li, Wenqian Li

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A quantitative method to monitor STING degradation with dual-luciferase reporters by Tsumugi Shoji, Kanako Sato, Ayumi Shinojima, Shogo Koide, Ruri Shindo, Kazune Hongo, Kojiro Mukai, Yoshihiko Kuchitsu, Tomohiko Taguchi

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Harnessing Bacteriophages for Sustainable Crop Protection in the Face of Climate Change by Robert Czajkowski, Amalia Roca, Miguel A. Matilla

“…ABSTRACT Crop pathogens represent a major challenge to global food security, causing over 40% yield losses in key crops and annual economic impacts estimated at up to US$290 billion. …”
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Investigating the Antimicrobial Activity of Anuran Toxins by Manuela B. Pucca, Anne Grace A. C. Marques, Ana Flávia M. Pereira, Guilherme Melo-dos-Santos, Felipe A. Cerni, Beatriz C. S. Jacob, Isabela G. Ferreira, Rafael L. Piccolo, Marco A. Sartim, Wuelton M. Monteiro, Isadora S. Oliveira

“…Among these compounds, toxins with potent antimicrobial properties stand out due to their ability to combat a broad spectrum of microbial pathogens. We explore the chemical diversity of these secretions, analyzing their modes of action and their potential applications in combating antibiotic-resistant bacteria and other pathogens. …”
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Methods of Control of Parasitic Weeds of the Genus <i>Cuscuta</i>—Current Status and Future Perspectives by Lyuben Zagorchev, Tzvetelina Zagorcheva, Denitsa Teofanova, Mariela Odjakova

“…Current research is exploring biological control methods, including allelopathic compounds, host-specific fungal pathogens, and epiparasitic insects, though these methods remain largely experimental. …”
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Gut Microbiota Dysbiosis: Pathogenesis, Diseases, Prevention, and Therapy by Yao Shen, Nairui Fan, Shu‐xia Ma, Xin Cheng, Xuesong Yang, Guang Wang

“…ABSTRACT Dysbiosis refers to the disruption of the gut microbiota balance and is the pathological basis of various diseases. The main pathogenic mechanisms include impaired intestinal mucosal barrier function, inflammation activation, immune dysregulation, and metabolic abnormalities. …”
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Chinese soy-based microbiome and associated microbial risks: a metagenomic investigation by Xuesong Xiang, Yingying Li, Junbin Ye, Baolong Li, Guozhong He, Mingyu Zhu, Jiawen Zhang, Bike Zhang, Ming Miao, Yuexin Yang

“…Our findings underscore the need to integrate microbial surveillance into traditional fermentation to balance health benefits with food safety.…”
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Microbiological mechanisms of oral mucosal disease: oral-intestinal crosstalk and probiotic therapy by Qi Zhou, Panpan Liu, Muni Chen, Hao He, Mengting Xu, Qianrong Xu, Jianfeng Yu, Yutian Deng, Jiayu Yan, Jiayu Yan, Jiayu Yan, Yueqiang Wen

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Diabetic testicular dysfunction and spermatogenesis impairment: mechanisms and therapeutic prospects by Wenxiu Zhang, Li Tong, Baofang Jin, Dalin Sun

“…Diabetes-induced testicular damage involves alterations in testicular cell function, hormone levels, and the integrity of the blood-testis barrier (BTB), ultimately disrupting spermatogenesis. …”
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Optimization of the therapy of ARVI and influenza in outpatient practice by D. S. Sukhanov, V. V. Basina, Yu. S. Alekseeva, E. V. Timofeev

“…Neuraminidase inhibitors, like cap-dependent endonuclease inhibitors, are used in the treatment of influenza A and B, and, unfortunately, are not active against other pathogens of acute respiratory viral infections. Due to the lack of drugs with direct antiviral action active against acute respiratory viral infections pathogens, the main etiotropic drugs are drugs of indirect (immunomodulatory) action with a wide antiviral spectrum, which include interferon inducers.Conclusion. …”
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An analysis of HRCT imaging characteristics and sputum culture results in hospitalized patients with community-acquired pneumonia - an institutional observational study by Keesari Sai Sandeep Reddy, Priyadarshini Varadaraj, Subbaiah Senthilnathan, Vivekanandan T, Gunasekaran N

“…Sputum samples were collected and cultured for bacterial pathogens. Data on patient demographics, HRCT findings, and sputum culture results were analyzed to identify correlations between imaging patterns and pathogens. …”
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Improving the effectiveness of eradication therapy for Helicobacter pylori infection by E. A. Ljaljukova, E. N. Chernysheva

“…Butyric acid (butyrate) is a short-chain fatty acid produced by anaerobic bacteria of the species Eubacterium rectale, Eubacterium ramulus, Eubacterium hallii, Roseburia cecicola, Roseburia faecis, Faecalibacterium prausnitzii and Coprococcus faecalis, as well as Fusobacteria, non-pathogenic Clostridium species, plays a key role in the physiology of the gastrointestinal epithelium. …”
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Nanotechnology-Based Strategies for Combating Emerging and Re-emerging Fungal Infections by Farnoush Asghari-Paskiabi1*, Zahra Jahanshiri1

“…The emergence and re-emergence of pathogenic fungi pose a significant challenge, fueled by factors like increased immunosuppression and climate changes. …”

Isoform analysis of heterozygous putative splicing variants at the allele level using nanopore long-read sequencing by Kokoro Ozaki, Takashi Irioka, Shohei Noma, Akira Machida, Moe Fukunaga, Tatsuro Murano, Chitose Takahashi, Michihira Tagami, Tsugumi Kawashima, Tomoko Hirata, Yuki Yasuoka, Hiroya Kuwahara, Toshiyuki Araki, Ken Yagi, Hidehiro Mizusawa, Kinya Ishikawa, Yasushi Okazaki, Takanori Yokota

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Cuproptosis-driven nanostrategies: Synergistic nanoplatforms for tumor microenvironment reprogramming and enhanced anticancer efficacy by Haipeng Cheng, Lin Zhao, Jing Cai

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<i>ZmNLR</i><i>-7</i>-Mediated Synergistic Regulation of ROS, Hormonal Signaling, and Defense Gene Networks Drives Maize Immunity to Southern Corn Leaf Blight by Bo Su, Xiaolan Yang, Rui Zhang, Shijie Dong, Ying Liu, Hubiao Jiang, Guichun Wu, Ting Ding

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High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy by Hanxiang Xu, Shizhuo Mu, Jingxuan Bao, Christos Davatzikos, Haochang Shou, Li Shen

“…Unfortunately, the pathogenic mechanisms behind AD are not yet clear and the treatment options are still limited. …”
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