Coniontins, lipopetaibiotics active against Candida auris identified from a microbial natural product fractionation library by Xuefei Chen, Kalinka Koteva, Sommer Chou, Allison Guitor, Daniel Pallant, Yunjin Lee, David Sychantha, Shawn French, Dirk Hackenberger, Nicole Robbins, Michael A. Cook, Eric D. Brown, Lesley T. MacNeil, Leah E. Cowen, Gerard D. Wright

“…Abstract The rise of drug-resistant fungal pathogens, including Candida auris, highlights the urgent need for innovative antifungal therapies. …”
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Interplay between fungal infections and autoimmunity: mechanisms and therapeutic perspectives by Devon T DiPalma, Miranda K Lumbreras, Mari L Shinohara

“…Emerging evidence highlights how fungal pathogens contribute to autoimmune processes by triggering immune dysregulation. …”
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Organizing the Chaos: Novel Insights into the Regulation of Z-3-Hexenal Production in Damaged Maize Leaves by Samantha Selman, Marie Engelberth, Jurgen Engelberth

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Biodiversity and Antimicrobial Potential of Acidophilic and Acidotolerant Actinomycetes by A. V. Chumak, O. N. Sineva

“…The spread of antibiotic resistance in pathogenic microorganisms is one of the main problems of modern medicine. …”
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Genome assembly of the grassland caterpillar Gynaephora qinghaiensis by Youpeng Lai, Shan Xiao, Minggang Qin, Xinhai Ye, Fang Wang, Qi Fang

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Hematological parameters in patients with bloodstream infection: A retrospective observational study by Wei Tang, Wanchun Zhang, Xin Li, Juan Cheng, Zhou Liu, Qiang Zhou, Shihe Guan

“…Conclusions: The specific combinations of hematological parameters can improve the power to distinguish patients with BSI caused by different pathogens. Attention to these parameters can be easily integrated into daily medical activities, without extra costs. …”
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Case Report: A first case of desmin-related myofibrillar myopathy due to inheritance from a confirmed mosaic asymptomatic carrier by Jelle Vlaeminck, Sophie Uyttebroeck, Elke De Schutter, Ann Cordenier, Shauni Wellekens, Erwin Ströker, Kelly De Rooms, Christine Helsen, Frederik J. Hes, Philippe Giron

“…Desmin-related myofibrillar myopathy is a hereditary disorder caused by pathogenic variants in the DES gene (MIM*125660), altering desmin, a muscle-specific intermediate filament which is crucial for sarcomere integrity. …”
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The Comparative Characteristics of Spontaneous Infection of Ticks in Natural Foci of Bacterial Tick-Borne Infections in Natural Foci in the Western and Eastern Baikal Region by D. O. Kiselev, Yu. P. Dzhioev, I. V. Kozlova, L. A. Stepanenko, A. A. Badmaev, V. I. Zlobin

“…The study of natural foci of infections transmitted by ticks is an integral part of the study of the clinical and epidemiological characteristics of this group of diseases and their manifestations in various endemic areas.The aim of this work was to obtain up-to-date information regarding the spread of the most epidemically significant pathogens of bacterial infections carried by ticks in natural foci of the Baikal region using molecular analysis methods.Materials & Methods. …”
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Lyophilised Reverse Transcriptase and Polymerase for Point‐of‐Care Diagnostics of SARS‐CoV‐2 by Natalie Mutter, Barbara Posch, Yasmin Gillitschka, Nadezhda Kataeva, Birgit Michalek, Daniel Lager, Filip Staniszewski, Alexandra Schilder, Lidiya Osinkina, Maximilian Westenthanner, Joachim Stehr, Federico Buersgens, Johannes R. Peham

“…ABSTRACT Early diagnosis of pathogens is key to reducing their spreading and to preventing severe health risks. …”
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A broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance by Wenyan He, Xueting Huan, Yinchuan Li, Qisen Deng, Tao Chen, Wen Xiao, Yijun Chen, Lingman Ma, Nan Liu, Zhuo Shang, Zongqiang Wang

“…Abstract The rapid emergence of difficult-to-treat multidrug-resistant pathogens, combined with the scarcity of antibiotics possessing novel mechanisms, poses a significant threat to global public health. …”
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Recent Advances in Detection and Control Strategies for Foodborne Bacteria in Raw and Ready‐to‐Eat Fruits and Vegetables by Asem M. Abdelshafy, Hala A. Younis, Ahmed I. Osman, Saleh M. Hussein, Amr S. Abou El‐Ela, Elsayed A. Mahmoud, Osama Elsherbiny, Ahmed K. Rashwan

“…This article extensively explores recent advancements in the detection of foodborne pathogens in uncooked and ready‐to‐eat fruits and vegetables, alongside potential prevention strategies. …”
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OXA-204 Carbapenemase in Clinical Isolate of Pseudomonas guariconensis, Tunisia by Nadia Jaidane, Wejdene Mansour, Lamia Tilouche, Pierre Châtre, Pauline François, Agnese Lupo, Saoussen Oueslati, Aymeric Jacquemin, Ali Lazzem, Sonia Karaborni, Laetitia Du Fraysseix, Yomna Ben Lamine, Nidhal Mahdhi, Abdelhalim Trabelsi, Jean-Yves Madec, Marisa Haenni, Thierry Naas

“…Surveillance, diagnostic tools, and antimicrobial drug access are needed to mitigate spread of carbapenem-resistant pathogens. …”
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Diagnosis of Tropheryma whipplei pneumonia using targeted nanopore sequencing: a rare case report and literature review by Miao Yu, Wenbin Wang, Wei Chen, Kexin Ye, Yuqing Zhou, Deep K. Vaishnani, Chen Chen, Xuancheng Jin, Xiaojun Zhu, Jun Ma, Fengfei Qian, Xiaohua Zhong, Chuanhua Nie

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MreB: unraveling the molecular mechanisms of bacterial shape, division, and environmental adaptation by Yaqi Wang, Yalan jiang, Zhixuan Song, Chengbin Zhu, Yujun Tang, Jiaofeng Peng, Peng Liu

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BCAA insufficiency leads to premature ovarian insufficiency via ceramide‐induced elevation of ROS by Xiao Guo, Yuemeng Zhu, Lu Guo, Yiwen Qi, Xiaocheng Liu, Jinhui Wang, Jiangtao Zhang, Linlin Cui, Yueyang Shi, Qichu Wang, Cenxi Liu, Guangxing Lu, Yilian Liu, Tao Li, Shangyu Hong, Yingying Qin, Xuelian Xiong, Hao Wu, Lin Huang, He Huang, Chao Gu, Bin Li, Jin Li

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A Missense Mutation in IRS1 is Associated with the Development of Early-Onset Type 2 Diabetes by Juyi Li, Shan Sun, Xiufang Wang, Yarong Li, Hong Zhu, Hongmei Zhang, Aiping Deng

“…KEGG (Kyoto Encyclopedia of Genes and Genomes) and PPI (protein-protein interaction) analysis were conducted using the DAVID (Database for Annotation, Visualization, and Integrated Discovery) and the STRING online analysis tools for the candidate pathogenic gene. …”
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Dysbiosis and extraintestinal cancers by Ruishan He, Pingqian Qi, Linzhen Shu, Yidan Ding, Peng Zeng, Guosheng Wen, Ying Xiong, Huan Deng

“…Despite recent advances in the remarkable correlation between dysbiosis and extraintestinal cancers, the underlying mechanisms are yet to be fully elucidated. Pathogenic microbiota, along with their metabolites, can undermine the integrity of the gut barrier through inflammatory or metabolic pathways, leading to increased permeability and the translocation of pathogens. …”
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Intestinal-region-specific functions of AHR in intrinsic enteric neurons during infections by Zijia Sun, Yingsheng Wang, Shaorui Liu, Hui Li, Danyang He, Heping Xu

“…The mechanisms by which iENs sense and integrate dietary and microbial signals to regulate intestinal homeostasis and inflammation remain unclear. …”
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Protein nanocages: A new frontier in mucosal vaccine delivery and immune activation by Lavanya Agnes Angalene J, Paopachapich Pa, Chheng Y Seng, Joon Haeng Rhee, Shee Eun Lee

“…Mucosal infectious diseases represent a significant global health burden, impacting millions of people worldwide through pathogens that invade the respiratory, gastrointestinal, and urogenital tracts. …”
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Role of the microbiome in regulation of the immune system by Songhui Kim, Cebile Ndwandwe, Hannah Devotta, Lamiah Kareem, Lu Yao, Liam O’Mahony

“…These in turn protect against aberrant inflammatory or hyper-reactive processes and promote effector immune responses that quickly eliminate pathogens, such as SARS-CoV-2. Potent tolerance mechanisms should ensure that these immune cells do not over-react to non-pathogenic factors (e.g. food proteins), while maintaining the ability to respond to infectious challenges in a robust, effective and well controlled manner. …”
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