Predicting reticuloruminal pH and subacute ruminal acidosis of individual cows using machine learning and Fourier-transform infrared spectroscopy milk analysis by T. Touil, F. Huot, S. Claveau, A. Bunel, D. Warner, D.E. Santschi, R. Gervais, É.R. Paquet

“…ABSTRACT: Low reticuloruminal pH (rpH) for a prolonged period could lead to SARA. …”
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Community engagement and chronic viral hepatitis public health interventions: a systematic review, meta-analysis, and complementary crowdsourcing open callResearch in context by Yifan Li, Eneyi Kpokiri, Dalia Elasi, Rongrong Sheng, Keying Wang, Hayley Conyers, Ye Zhang, Danjuma K. Adda, Philippa C. Matthews, Thomas Fitzpatrick, Joseph D. Tucker, Dan Wu

“…To summarize the current state of knowledge on this topic we performed a systematic review and a crowdsourcing open call. Methods: A parallel mixed-methods approach was used in this study. …”
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A single HIIT session does not alter blood sphingolipid levels in healthy young adults: The SphingoHIIT randomized controlled trial by Thomas Angst, Nadia Weber, Seraina Fischer, Joëlle Lehmann, Denis Infanger, Tony Teav, Fabian Schwendinger, Lukas Streese, Timo Hinrichs, Ilaria Croci, Christian Schmied, Hector Gallart-Ayala, Christoph Höchsmann, Karsten Koehler, Henner Hanssen, Arno Schmidt-Trucksäss, Julijana Ivanisevic, Justin Carrard

“…Ceramide-based scores were developed, predicting cardiometabolic risk independently of and beyond low-density lipoprotein cholesterol. To date, it remains largely unknown whether exercise can modulate sphingolipid levels. …”
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Identification and Analysis of Effective Factors on the Trend of the Iranian Banking Network to Implement Green Banking by W. Qelich

“…In the sub-criteria section, the high inflation rate, the relative cheapness of energy prices and the presence of profitable parallel markets along with green deposits are mentioned as the most important reasons for the low tendency towards green banking. …”
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A human visual cognitive mechanism based network for surface defect detection(基于人类视觉认知机制的表面缺陷检测) by 崔丽莎(CUI Lisha), 代润鹏(DAI Runpeng), 姜晓恒(JIANG Xiaoheng), 李飞蝶(LI Feidie), 陈恩庆(CHEN Enqing), 徐明亮(XU Mingliang)

“…Specifically, at the macro level, by simulating the working principles of the foveal and parafoveal areas on the retina, a parallel backbone network consisting of a foveal vision branch and a peripheral vision branch is proposed, learning high spatial frequency local details and low spatial frequency global semantics from defective images. …”
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Globo H-KLH vaccine adagloxad simolenin (OBI-822)/OBI-821 in patients with metastatic breast cancer: phase II randomized, placebo-controlled study by Sung-Bae Kim, Hope S Rugo, Sara A Hurvitz, Hong-Tai Chang, Chiun-Sheng Huang, Su-Hua Lee, Jung-Tung Hung, Shir-Hwa Ueng, Shin-Cheh Chen, Alice L Yu, Ling-Ming Tseng, Louis W C Chow, Ming-Feng Hou, Richard B Schwab, James L Murray, Hsien-Kun Chang, Chwen-Cheng Chen

“…Purpose This randomized, double-blind, placebo-controlled, parallel-group, phase II trial assessed the efficacy and safety of adagloxad simolenin (OBI-822; a Globo H epitope covalently linked to keyhole limpet hemocyanin (KLH)) with adjuvant OBI-821 in metastatic breast cancer (MBC).Methods At 40 sites in Taiwan, USA, Korea, India, and Hong Kong, patients with MBC of any molecular subtype and ≤2 prior progressive disease events with stable/responding disease after the last anticancer regimen were randomized (2:1) to adagloxad simolenin (AS/OBI-821) or placebo, subcutaneously for nine doses with low-dose cyclophosphamide. …”
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Effects of 12 Weeks of Interval Block Resistance Training Versus Circuit Resistance Training on Body Composition, Performance, and Autonomic Recovery in Adults: Randomized Controll... by Héctor Fuentes-Barría, Raúl Aguilera-Eguía, Juan Maureira-Sánchez, Miguel Alarcón-Rivera, Victor Garrido-Osorio, Olga Patrica López-Soto, Juan Alberto Aristizábal-Hoyos, Lissé Angarita-Davila, Diana Rojas-Gómez, Valmore Bermudez, Cherie Flores-Fernández, Ángel Roco-Videla, Jorge Enrique González-Casanova, Sebastian Urbano-Cerda, Dan Iulian Alexe

“…<b>Methods:</b> A randomized, parallel, double-blind study was conducted with 30 participants assigned to IBRT (n = 15) or CRT (n = 15). …”
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Discovery and validation of biomarkers for Parkinson’s disease from human cerebrospinal fluid using mass spectrometry-based proteomics analysisResearch in context by Sungtaek Oh, Jaehun Jung, Jinhyeok Kim, Yura Jang, Catherine C. Bakker, Alexander Y. Pantelyat, Zhen Zhang, Ted M. Dawson, Chan Hyun Na, Liana S. Rosenthal

“…We validated our findings using parallel reaction monitoring mass spectrometry with an independent cohort of CSF samples (80 PD, 80 controls). …”
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Future Proofing Study: a cluster randomised controlled trial evaluating the effectiveness of a universal school-based cognitive–behavioural programme for adolescent depression by Maree Teesson, Helen Christensen, Svetha Venkatesh, Aliza Werner-Seidler, Lara Johnston, Bridianne O’Dea, Michelle Torok, Katharine Steinbeck, Raghu Lingam, Andrew Mackinnon, Yael Perry, Kit Huckvale, Joanne R Beames, Alison L Calear, Kate Maston, Philip J Batterham, Ju Lee Oei, Mark E Larsen, Jennifer L Hudson, Lyndsay Brown, Hiroko Fujimoto, Alexandra Batholomew, Debopriyo Bal, Susan Rachel Skinner, Katherine M Boydell, Susanne Schweizer

“…However, high-quality, large-scale trials are lacking.Objective The aim was to examine whether a digital cognitive–behavioural programme (‘SPARX’), delivered at scale in schools, would reduce depressive symptoms 12 months later.Methods A cluster randomised controlled trial with parallel arms (intervention; control) was conducted in Australian schools, between August 2019 and December 2022. …”
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Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

“…Abstract Background Systematic genomics-guided population-based studies on the neglected malaria parasites, P. malariae, P. ovale curtisi, and P. ovale wallikeri species remain challenging due to their low parasitemia, underestimation, and lack of comprehensive genetic analysis. …”
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mHealth Social Support Versus Standard Support for Diabetes Management in Safety-Net Emergency Department Patients: Randomized Phase-III Trial by Elizabeth Burner, Danielle Hazime, Michael Menchine, Wendy Mack, Janisse Mercado, Adriana Aleman, Antonio Hernandez Saenz, Sanjay Arora, Shinyi Wu

“… BackgroundMobile health (mHealth) is a low-cost method to improve health for patients with diabetes seeking care in safety-net emergency departments, resulting in improved medication adherence and self-management. …”
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Direct comparison of an ultrasensitive real-time PCR assay with droplet digital PCR for the detection of PIK3CA hotspot mutations in primary tumors, plasma cell-free DNA and paired... by Stavroula Smilkou, Loukas Kaklamanis, Ioanna Balgouranidou, Helena Linardou, Alkistis Maria Papatheodoridi, Flora Zagouri, Evangelia Razis, Stylianos Kakolyris, Amanda Psyrri, Christos Papadimitriou, Athina Markou, Evi Lianidou

“…All FFPEs and plasma-cfDNA samples were analyzed in parallel for PIK3CA mutations by ultrasensitive real-time PCR assay and droplet digital PCR.ResultsIn gDNAs from FFPEs, using ultrasensitive real-time PCR, the p.E545K mutation was detected in 22/42(52.4%), and the p.E542K and p.H1047R mutations were detected in 14/42(33.3%) and 16/42(38.1%), respectively. …”
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ARC (Australian Rotator Cuff) trial: study protocol for a randomised placebo-controlled trial comparing rotator cuff repair to no repair during arthroscopic shoulder surgery for pe... by Ian A. Harris, Richard S. Page, Rachelle Buchbinder, Ville Äärimaa, Sam Adie, Graeme Brown, Nancy Cinnadaio, Maurizio Damiani, Joseph Descallar, Manuela L. Ferreira, Nadine E. Foster, Stephen Gill, Katrina Hutchison, Teppo Järvinen, Oliver Khoo, David Lieu, Christopher G. Maher, Justine M. Naylor, Geoff Smith, Luke Spencer, Yvana Toh, Andrew Whan, Tim Yeoh

“…Methods The study is a multicentre two-parallel arm, blinded, individually randomised controlled trial (RCT). …”
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Film Properties of Heparin Cross-Linked with Epichlorohydrin in Absence or Presence of Imidazole by Ivan Šimkovic, Filip Gucmann, Michal Hricovíni, Raniero Mendichi, Edmund Dobročka, Alberto Giacometti Schieroni, Daniele Piovani, Stefania Zappia, Miloš Hricovíni

“…This could be explained by the parallel cross-linking of H only with E within its serine end unit and in competition with only one nitrogen of I. …”
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Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-control... by Dana M. Otzel, Dana M. Otzel, Larissa Nichols, Christine F. Conover, Stephen A. Marangi, Jayachandra R. Kura, Dominic K. Iannaccone, David J. Clark, David J. Clark, Chris M. Gregory, Christopher F. Sonntag, Anita Wokhlu, Anita Wokhlu, Hans K. Ghayee, Michael J. McPhaul, Charles E. Levy, Charles A. Plumlee, Charles A. Plumlee, Robert B. Sammel, Robert B. Sammel, Kevin T. White, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow, Joshua F. Yarrow

“…Men with spinal cord injury (SCI) exhibit neuromuscular impairment, muscle atrophy, bone loss, and increased central adiposity, along with low testosterone. However, sparse evidence supports TRT efficacy after SCI.MethodsThis parallel-group, double-blind, placebo-controlled, and randomized clinical trial (RCT) is a pilot study that enrolled men (N = 12) with low to low–normal testosterone and gait impairments after chronic motor-incomplete SCI. …”
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Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology. by Emily Heath, Noelia Begue-Pastor, Sridhar Chaganti, Debbie Croom-Carter, Claire Shannon-Lowe, Dieter Kube, Regina Feederle, Henri-Jacques Delecluse, Alan B Rickinson, Andrew I Bell

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Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT by Cherry-Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin VE Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones, Enitan D Carrol

“…Design A pragmatic, multicentre, open-label, parallel two-arm, individually randomised controlled trial with internal pilot phase, qualitative study and health economic evaluations. …”
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The Effect of Weight Loss in Obese Patients with Chronic Stable Plaque-Type Psoriasis by Wanjarus Roongpisuthipong, Marinya Pongpudpunth, Chulaporn Roongpisuthipong, Natta Rajatanavin

“…Chronic plaque psoriasis is frequently associated with obesity. The effect of a low-calorie diet on psoriasis has not been investigated. …”
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Measurement report: Optical and structural properties of atmospheric water-soluble organic carbon in China – insights from multi-site spectroscopic measurements by H. Chen, C. Yan, C. Yan, C. Yan, L. Huang, L. Huang, L. Du, L. Du, Y. Yue, X. Wang, Q. Chen, M. Xie, J. Liu, F. Wang, S. Fang, Q. Yang, H. Niu, M. Zheng, Y. Wu, L. Xue

“…Multiple linear regression analysis shows that the fluorophores identified by fluorescence spectra combined with parallel factor analysis (PARAFAC) contribute to about 62 %–93 % of<span id="page3648"/> the WSOC light absorption at all sites, in which humic-like substance (HULIS) contributes the most, especially highly oxygenated HULIS (29 %–50 %) with long emission wavelengths. …”
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Management of Local Skin Reactions Caused by 5-FU 4% Cream for the Treatment of Actinic Keratosis: A Delphi Consensus by Gabriella Brancaccio, Giulia Briatico, Zoe Apalla, Reinhard Dummer, Jan Eklind, Nicole Basset Seguin, Brigitte Dreno, Maria Concetta Fargnoli, Pascale Guitera, Markus V. Heppt, Christoph Hoeller, Thomas Jouary, Aimilios Lallas, Ulrikke Lei, Ulrike Leiter, Josep Malvehy, David Moreno Ramirez, John Paoli, Ketty Peris, Susanna Puig, Philippe Saiag, Eggert Stockfleth, Wilhelm Stolz, Alexander J. Stratigos, Class Ulrich, Ann-Marie Wennberg, Iris Zalaudek, Giuseppe Argenziano

“…The use of emollients (in parallel with the treatment with 5-FU) was considered not needed by most (moderate consensus, 64.3%). …”
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