Transcriptional profile features in patients with early and late preeclampsia by V. E.A. Kotelnikova, D. E. Pantyukhova, F. D. Ablyamitova, S. N. Vikinskaya, Kh. U. Khalilova, L. F. Mustafaeva, D. A. Barieva, D. V. Yarovaya, N. D. Chopik, M. S. Ermakova, L. E. Sorokina

“…The prospective observational comparative study in parallel groups enrolled 43 pregnant women divided into 2 groups: main group – 23 pregnant women with diagnosed PE and control group – 20 apparently healthy women with uncomplicated pregnancy course, delivery and the postpartum period. …”
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CO-CREATION-HF protocol: clinical trial to evaluate the impact of a comprehensive and hybrid cardiac rehabilitation model on patients with heart failure by Pamela Seron, Daniela Gómez-Pérez, Edgardo Opazo-Díaz, Maria Jose Oliveros, Maria Francisca Contreras, Alejandra Salinas, Omar Andrade-Mayorga, Gabriel Nasri Marzuca-Nassr, Kathleen Saavedra, Cinthya Espejo, Sergio Muñoz, Fernando Lanas, Sherry L. Grace, Sherry L. Grace

“…IntroductionComprehensive, hybrid cardiac rehabilitation (CR) models have been scantly investigated in heart failure (HF) populations, particularly in low-resource settings. CO-CREATION-HF aims to evaluate the effectiveness of such a model compared to supervised exercise alone.Methods and analysisA 2 parallel-arm, multi-center randomized clinical superiority trial will be conducted with blinded outcome assessment. 152 HF patients (NYHA class II or III) will be recruited consecutively, and randomly assigned using permuted blocks; allocation will be concealed. …”
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Randomised controlled trial of perinatal vitamin D supplementation to prevent early-onset acute respiratory infections among Australian First Nations children: the ‘D-Kids’ study p... by Anne B Chang, Peter S Morris, Tom Snelling, Paul V Licciardi, Michael J Binks, David Simon, E Kim Mulholland, Adrienne Kirby, Heather D'Antoine, Amy S Bleakley, Susan J Pizzutto, Michelle Lamberth, Verity Powell, Jane Nelson, Geetha Rathnayake, Amanda J Leach

“…While ARI-related mortality is low in Australia, First Nations infants are hospitalised with ARIs up to nine times more often than their non-First Nations counterparts. …”
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MORPHOLOGY OF OCCLUSAL SURFACE OF DECIDUOUS MOLARS AFTER ENAMEL ACID ETCHING by N.V. Bidenko

“…However the prismatic structure in fissures was generally covered with aprismatic layer with border parallel to fissure direction. There were no quality etching in majority of fissure areas. …”
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Tai Chi as a mind-body exercise modulates endothelial function in coronary artery disease: A randomized clinical trial by Yameng Li, Cuihan Li, Jiansheng Wen, Meize Cui, Qiuyang Wei, Mingyu Liu, Zaihao Chen, Hui Fang, Linli Liu, Jiahao Fu, Jianwei Zhang, Shaojun Lyu

“…However, the effects of TC on endothelial function in CAD patients compared to aerobic exercise (AE) remain understudied. Design: A parallel-group, assessor-blinded, randomized clinical trial (RCT). …”
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Development and Implementation of MyPainHub, a Web-Based Resource for People With Musculoskeletal Conditions and Their Health Care Professionals: Mixed Methods Study by Kerrie Evans, Jonathan Ko, Dragana Ceprnja, Katherine Maka, Darren Beales, Michele Sterling, Kim L Bennell, Gwendolen Jull, Paul W Hodges, Marnee J McKay, Trudy J Rebbeck

“… BackgroundMusculoskeletal conditions, including low back pain (LBP), neck pain, and knee osteoarthritis, are the greatest contributors to years lived with disability worldwide. …”
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Determining the feasibility of a codesigned and personalised intervention (Veg4Me) to improve vegetable intake in young adults living in rural Australian communities: protocol for... by Ralph Maddison, John C Mathers, Sarah A McNaughton, Lauren C Blekkenhorst, Katherine M Livingstone, Gavin Abbott, Laura Alston, Jonathan C Rawstorn, Eric O, Yuxin Zhang, Scott Barnett, Stephanie R Partridge, Stephanie L Godrich, Gilly A Hendrie, Kate Dullaghan

“…Introduction Diets low in vegetables are a main contributor to the health burden experienced by young adults in rural communities. …”
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Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heart by Jialing Tang, Nanyoung Yoon, Keith Dadson, Hye Kyoung Sung, Yubin Lei, Thanh Q. Dang, Wing Yan Chung, Saher Ahmed, Ali A. Abdul-Sater, Jun Wu, Ren-Ke Li, James Jonkman, Trevor McKee, Justin Grant, Jeffrey D. Peterson, Gary Sweeney

“…First, we utilized a cellular model of hypoxia reoxygenation (H/R) in H9c2 cells cultured in low or high glucose (HG) and tested cell death using flow cytometry to detect Annexin-V and propidium iodide, imaging cell viability ReadyProbe and lactate dehydrogenase release. …”
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Identifying barriers and disparities in the healthcare of patients with alopecia areata: a mixed-methods analysis using claims data and qualitative interview data by Matthias Augustin, Christine Blome, Katharina Müller, Kristina Hagenström, Toni Maria Janke, Beke Hester, Theresa Klinger, Brigitte Stephan

“…Though 57.5% of patients received at least one drug prescription, mostly topical therapies, access to approved systemic drugs was very low. Drugs were prescribed mostly by general practitioners (41.1%) and dermatologists (32.8%). …”
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High-resolution 3D spatial distribution of complex microbial colonies revealed by mass spectrometry imaging by Yuting Shen, Yisu Wang, Jianing Wang, Peisi Xie, Chengyi Xie, Yanyan Chen, Niaz Banaei, Kangning Ren, Zongwei Cai

“…Methods: This article introduces the moisture-assisted cryo-section (MACS) method, enabling embedding-free sectioning parallel to the growth plane. The MACS method secures intact sections by controlling ambient humidity and slice thickness, preventing molecular delocalization. …”
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A Three-Stage-Concatenated Non-Linear MMSE Interference Rejection Combining Aided MIMO-OFDM Receiver and its EXIT-Chart Analysis by Jue Chen, Siyao Lu, Tsang-Yi Wang, Jwo-Yuh Wu, Chih-Peng Li, Soon Xin Ng, Robert G. Maunder, Lajos Hanzo

“…This reduced complexity NL detection algorithm is particularly well suited for practical hardware implementation using parallel processing at a low latency. Briefly, the proposed scheme employs the MMSE-IRC detector for mitigating the interference. …”
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Chatbot-Delivered Stage of Change–Tailored Web-Based Intervention to Promote Physical Activity Among Inactive Community-Dwelling People Aged 65 years or More: Protocol for a Random... by Xue Liang, Fenghua Sun, Qingpeng Zhang, Yuan Fang, Fuk-yuen Yu, Danhua Ye, Borui Zhang, Qianwen Liao, Phoenix KH Mo, Zixin Wang

“…MethodsThis is a partially blinded (outcome assessors and data analysts) and parallel-group RCT. A total of 278 inactive community-dwelling people aged 65 years or more will be randomized evenly into either an intervention group or a control group. …”
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Evaluating the Effectiveness of a Roblox Video Game (Super U Story) in Improving Body Image Among Children and Adolescents in the United States: Randomized Controlled Trial by Nicole Paraskeva, Sharon Haywood, Jason Anquandah, Paul White, Mahira Budhraja, Phillippa C Diedrichs, Heidi Williamson

“…Self-report engagement data suggested that participants experienced a highly variable and often low-dose exposure. ConclusionsThis large-scale, fully powered trial is the first to assess the effectiveness of a Roblox-based body image intervention, demonstrating the potential for disseminating microinterventions to children and adolescents on large and popular commercial platforms. …”
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Prevention of premature birth in female patients with bacterial vaginosis using a complex of natural antimicrobial peptides and cytokines by A. A. Sukhanov, G. B. Dikke, I. I. Kukarskaya, N. V. Shilova

“…The number of newborns weighing less than 2500 g was significantly lower from paired mothers who received Superlymph® + Metronidazole comprising 2.9 % vs. 15.6 % treated with Metronidazole alone (p = 0.03), whereas a risk of low birth weight neonates was decreased by 6-fold (RR = 0.16; 95 % CI = 0.03–0.88). …”
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Dietary iron interacts with diet composition to modulate the endocannabinoidome and the gut microbiome in mice by Fredy Alexander Guevara Agudelo, Nadine Leblanc, Isabelle Bourdeau-Julien, Gabrielle St-Arnaud, Fadil Dahhani, Nicolas Flamand, Alain Veilleux, Vincenzo Di Marzo, Frédéric Raymond

“…Here, we evaluated how 28 days of Fe depletion and enrichment, in interaction with Low Fat-Low Sucrose (LFLS) or High Fat-High Sucrose (HFHS) diets, affect the host via the eCBome, and modulate intestinal gut microbial communities. …”
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DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencing by Junwei Song, Li-an Lin, Chao Tang, Chuan Chen, Qingxin Yang, Dan Zhang, Yuancun Zhao, Han-cheng Wei, Kepan Linghu, Zijie Xu, Tingfeng Chen, Zhifeng He, Defu Liu, Yu Zhong, Weizhen Zhu, Wanqin Zeng, Li Chen, Guiqin Song, Mutian Chen, Juan Jiang, Juan Zhou, Jing Wang, Bojiang Chen, Binwu Ying, Yuan Wang, Jia Geng, Jing-wen Lin, Lu Chen

“…Abstract Nanopore direct RNA sequencing (DRS) is a powerful tool for RNA biology but suffers from low basecalling accuracy, low throughput, and high input requirements. …”
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Experimental Study on The Mechanical Properties of Novel Viscous Mass Damper by CAI Yijie, XU Weizhi, WANG Shuguang, DU Dongsheng, SUN Yue

“…In terms of force magnitude, the maximum error was 42.5 kN, while the average error was as low as 20.97 kN. These results validate the effectiveness of the proposed formula and provide a reliable theoretical basis for the design of the NVMD. …”
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Innovation Ecosystem of Iran's Tourism Industry with Emphasis on Supply Chain by Azizolah Jafari, mahdi alaei kerahrudi

“…Although parallel institutions pose a problem, creating a mechanism to consolidate opinions, share resources, and achieve synergies can transform this challenge into an opportunity. …”
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Pyrazolone derivatives as corrosion inhibitors of copper in sulfuric acid solution by Rehab E. Azooz, Salah M. Abd El-Haleem, Ahmed Diab

“…Monte Carlo simulations indicated that PYs adsorbed in a parallel configuration, provide better cover¬age of the metal surface with high adsorption energy. …”
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Effectiveness of Chlorthalidone Plus Amiloride for the Prevention of Hypertension: The PREVER‐Prevention Randomized Clinical Trial by Sandra Costa Fuchs, Carlos E. Poli‐de‐Figueiredo, José A. Figueiredo Neto, Luiz César N. Scala, Paul K. Whelton, Francisca Mosele, Renato Bandeira de Mello, José F. Vilela‐Martin, Leila B. Moreira, Hilton Chaves, Marco Mota Gomes, Marcos R. de Sousa, Ricardo Pereira e Silva, Iran Castro, Evandro José Cesarino, Paulo Cesar Jardim, João Guilherme Alves, André Avelino Steffens, Andréa Araujo Brandão, Fernanda M. Consolim‐Colombo, Paulo Ricardo de Alencastro, Abrahão Afiune Neto, Antônio C. Nóbrega, Roberto Silva Franco, Dario C. Sobral Filho, Alexandro Bordignon, Fernando Nobre, Rosane Schlatter, Miguel Gus, Felipe C. Fuchs, Otávio Berwanger, Flávio D. Fuchs

“…Methods and Results This randomized, parallel, double‐blind, placebo‐controlled trial was conducted in 21 Brazilian academic medical centers. …”
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