Safety Monitoring of Omaveloxolone in Friedreich Ataxia: Results from One Year of Clinical Treatment by Katherine Gunther, Victoria Profeta, Medina Keita, Courtney Park, McKenzie Wells, Sonal Sharma, Kimberly Schadt, David R. Lynch

“…Few changes were noted in albumin or bilirubin, and such changes did not parallel changes in transaminases, suggesting they are independent events. …”
Get full text

Hybrid Graph Representation and Learning Framework for High-Level Synthesis Design Space Exploration by Pouya Taghipour, Eric Granger, Yves Blaquiere

“…Indeed, modeling HLS-related problems using GNNs that efficiently capture the complex patterns arising from applied pragmas and low-level characteristics of HLS specifications is challenging. …”
Get full text

Pursuit of Digital Innovation in Psychiatric Data Handling Practices in Ireland: Comprehensive Case Study by Rana Zeeshan, John Bogue, Amna Gill, Mamoona Naveed Asghar

“…ResultsOur study revealed outdated data management, heavy reliance on paperwork resulting in serious repercussions, parallel workload, alarmingly low readability of notes, and a nonviable setup that hinders research and analytical examination. …”
Get full text

Development of a Widely Accessible, Advanced Large-Scale Microfluidic Airway-on-Chip by Brady Rae, Gwenda F. Vasse, Jalal Mosayebi, Maarten van den Berge, Simon D. Pouwels, Irene H. Heijink

“…With our construction method, this larger culture area allows for easier handling, the potential for a wide range of exposures, as well as the collection of low-quantity samples (e.g., volatiles or mitochondrial RNA). …”
Get full text

Genotyping methods and their contributions to the study of tuberculosis dynamic in Latin America by Yasmin Castillos de Ibrahim das Neves, Ana Julia Reis, Nathália Xavier Maio, Júlia Vianna, João Perdigão, Ivy Bastos Ramis, Pedro Eduardo Almeida da Silva, Andrea von Groll

“…Results: Spacer oligonucleotide typing (spoligotyping) was the most widely used method in Latin America, with decreasing use in parallel with increasing use of mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) and whole genome sequencing (WGS). …”
Get full text

Climate-driven biogenic emissions alleviate the impact of human-made emission reductions on O₃ control in the Pearl River Delta region, southern China by N. Wang, N. Wang, S. Liu, J. Xu, Y. Wang, C. Li, Y. Xie, H. Lu, F. Yang

“…<p>Ozone (O<span class="inline-formula">₃</span>) concentrations in the Pearl River Delta (PRD) during summer are typically low and often overlooked. However, integrated observational data indicate a consistent increase in summer O<span class="inline-formula">₃</span> levels over recent decades (<span class="inline-formula">+</span>0.96 ppb yr<span class="inline-formula">⁻¹</span>), contradicting China's efforts to reduce anthropogenic emissions. …”
Get full text

Zenith Tropospheric Delay Forecasting in the European Region Using the Informer–Long Short-Term Memory Networks Hybrid Prediction Model by Zhengdao Yuan, Xu Lin, Yashi Xu, Jie Zhao, Nage Du, Xiaolong Cai, Mengkui Li

“…This model employs a parallel ensemble learning strategy that combines the strengths of both the Informer and LSTM networks to extract features from ZTD data. …”
Get full text

Comparison of SEEKflex/videolaryngoscopy and fibreoptic bronchoscope for awake tracheal intubation: a randomized clinical trial by Wenyun Xu, Chenglong Zhu, Qinghua Wu, Bin Zhao, Miao Zhou, Yang Liu, Yongchu Hu, Jianhua Xia, Hongbin Yuan, Yaohua Yu, Zui Zou

“…Methods We conducted a pragmatic, multicentre, non-blinded, randomized, parallel-group clinical trial in Shanghai and Putian, China. …”
Get full text

The Magnetic Keys to Massive Star Formation: The Western η Carinae Giant Molecular Cloud by Peter J. Barnes, Stuart D. Ryder, Giles Novak, Laura M. Fissel

“…In this massive clump sample, B fields provide enough support against gravity to explain their overall low star formation rate.…”
Get full text

Predicting tumor mutation burden and VHL mutation from renal cancer pathology slides with self‐supervised deep learning by Qingyuan Zheng, Xinyu Wang, Rui Yang, Junjie Fan, Jingping Yuan, Xiuheng Liu, Lei Wang, Zhuoni Xiao, Zhiyuan Chen

“…Methods We obtained whole slide images (WSIs) and somatic mutation data of 350 ccRCC patients from The Cancer Genome Atlas for developing SSL‐ABMIL model. In parallel, 163 ccRCC patients from Clinical Proteomic Tumor Analysis Consortium cohort was used as independent external validation set. …”
Get full text

Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods by Syed Shajid, ABHIJIT MANDAL, Kalyan Mondal, Gogul Priean V, Bratindranath Mukherjee, Praveen Chandra Pandey, Himanshu Mishra, Ritusha Mishra, Ganeshkumar Patel, Ankur Mourya, Lalit Aggarwal, Sunil Choudhary

“…The gel samples were refrigerated at various temperatures for 1 to 10 days and irradiated within a water bath environment utilizing a telecobalt unit (Phoenix, Theratronics) employing parallel opposed beams. Spectrophotometric analysis at  a wavelength of 585 nm was used to measured optical density changes with dose.. …”
Get full text

Vertical-Axis Wind Turbines in Emerging Energy Applications (1979–2025): Global Trends and Technological Gaps Revealed by a Bibliometric Analysis and Review by Beatriz Salvador-Gutierrez, Lozano Sanchez-Cortez, Monica Hinojosa-Manrique, Adolfo Lozada-Pedraza, Mario Ninaquispe-Soto, Jorge Montaño-Pisfil, Ricardo Gutiérrez-Tirado, Wilmer Chávez-Sánchez, Luis Romero-Goytendia, Julio Díaz-Aliaga, Abner Vigo-Roldán

“…Emerging applications in microgrids, building-integrated systems, and offshore floating platforms leverage VAWTs’ omnidirectional, low-noise operation, although challenges persist in scaling up, control integration, and long-term field validation. …”
Get full text

Key cellulase components synergizing with lactic acid bacteria to degrade alfalfa lignocellulose to improve lactic acid fermentation by Linxiong Ma, Junfeng Li, Wanyu Zhao, Jingyu Wang, Yanwen Li, Yueying Xiong, Yongchao He, Xiaohui Chu, Qinhua Liu, Qinhua Liu

“…Using cellulase to convert alfalfa lignocellulose into lactic acid (LA) is useful in low-temperature seasons to improve fermentation quality, but it is still unknown which specific cellulase component synergizes with lactic acid bacteria (LAB) to promote LA fermentation. …”
Get full text

Study on the Impact of Pipe Installation Height on the Hydraulic Performance of Combined Canal–Pipe Water Conveyance Systems by Yanan Liu, Meijian Bai, Kai Zhang, Baozhong Zhang, Yinong Li, Yuanpeng Wang, Jintao Liu, Hairuo Liu, Yutian He

“…When the flow rate is low, the water depth sharply decreases. Conversely, when the flow rate is higher, the water depth rises significantly. …”
Get full text

Repression of Connexin26 hemichannel activity protects the barrier function of respiratory airway epithelial cells against LPS-induced alteration by Tina Lehrich, Anne Dierks, Masina Plenge, Helena Obernolte, Klaudia Grieger, Katherina Sewald, Frederic Rodriguez, Lucie Malet, Peter Braubach, Florence Bedos-Belval, Anaclet Ngezahayo

“…After TEER recovery, CLDN4 TiJOR stayed reduced. Low concentrations (10 ng/mL LPS) required three times repeated application for barrier reduction and CLDN4 TiJOR reduction by 30%. …”
Get full text

Phenolic Acids and Their Relationship to Nutritional and Technological Grain Parameters of Durum Wheat Under Variable Treatment Intensity in Central European Conditions by Václav Dvořáček, Michal Jágr, Michael Jelínek, Ivana Polišenská, Tomáš Spitzer, Jiří Hermuth

“…UHPLC-ESI-MS/MS was used for the detection and accurate quantification of PAAs. In parallel, 12 other nutritional and basic technological parameters of the cereal were evaluated. …”
Get full text

THE KARDIOKANON STUDY: A WAY TO SETTLE THE SUBJECT OF CLINICAL EQUIVALENCE OF GENERIC AND ORIGINAL DRUGS by S. Yu. Martsevich, N. P. Kutishenko, M. L. Ginzburg, G. V. Matyushin, V. V. Skibitskiy, L. A. Sokolova, A. V. Deev

“…Patients (n=120), aged 40–72 (58.7±7.7) years, 93 men and 27 women, with stable angina, functional class (FC) II (n=117, 97.5%) and III (n=3, 2.5%), were included in the multi-center open randomized study with parallel groups. Patients were randomized into 2 groups: group 1 (n=59) received therapy with original drugs only , and group 2 (n=61) — with generics ones only. …”
Get full text

Effects of specific symbiotic supplements on anthropometric measurements, glycaemic control, and lipid profiles among individuals with type 2 diabetes mellitus in two teaching hosp... by Sarah Hayder Ali Zalzala, Ban Abdul-Ridha Salman Al-Hashimi, Zahraa Hayder Ali Zalzala, Khalid Saeed Fahad

“…Methods A double-blind, placebo-controlled, parallel clinical trial was conducted at two diabetes outpatient clinics. …”
Get full text

Stepwise autonomous orbit determination of large LEO constellations by GNSS observations with partial inter-satellite ranging by Yuanxi Yang, Xiaoyong Song

“…Abstract Large constellations composed of a great amount of Low Earth Orbit (LEO) satellites are widely applied in satellite communication, remote sensing, augmented satellite navigation, environment monitoring, and so on. …”
Get full text

Effect of a transtheoretical model-based intervention and motivational interviewing on hyperphosphatemia management via telehealth (TMT program) among hemodialysis patients during... by Arrom Thongsunti, Chatchawan Silpakit, Thanapoom Rattananupong, Wonngarm Kittanamongkolchai, Wonngarm Kittanamongkolchai, Wonngarm Kittanamongkolchai, Warangkana Sumethpimolchai, Vitool Lohsoonthorn

“…Non-adherence to phosphate binders and a low-phosphate diet behavior contribute to this issue. …”
Get full text