Differences in uni-dimensional breathlessness measures and thresholds for clinical response in a randomised controlled trial in people with chronic breathlessness: an exploratory s... by David Currow, Magnus Ekström, Miriam Johnson, Sandra Louw, Philip McCloud, Katherine Clark, Diana Ferreira

“…The aim of this study was to consider the performance of uni-dimensional measures in chronic breathlessness limiting exertion.Methods We report five measures of breathlessness (intensity: worst, best and average in the previous 24 hours; breathlessness now; and an affective component unpleasantness now) and two clinical thresholds over baseline on their 0–100 mm visual analogue scale (8.9 mm absolute improvement; and 15% relative improvement) collected in a multi-site, randomised, double-blind, parallel-arm, placebo-controlled trial of regular, low-dose, sustained-release morphine for people with chronic breathlessness with optimally treated underlying causes.Results Participants (n=284) were mostly elderly men with severe, chronic breathlessness. …”
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Lanthanide conjugate Pr-MPO elicits anti-cancer activity by targeting lysosomal machinery and inducing zinc-dependent cataplerosis by Gregory Lucien Bellot, Dan Liu, Marc Fivaz, Sanjiv K. Yadav, Charanjit Kaur, Shazib Pervaiz

“…Exposure of cancer cells to relatively low concentrations of the conjugate Pr-MPO (5 µM) significantly impairs cell survival in a p53-independent manner and irrespective of the drug resistant phenotype. …”
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MEFSR-GAN: A Multi-Exposure Feedback and Super-Resolution Multitask Network via Generative Adversarial Networks by Sibo Yu, Kun Wu, Guang Zhang, Wanhong Yan, Xiaodong Wang, Chen Tao

“…It processes low-resolution under- and over-exposed images to produce high-resolution high dynamic range (HDR) images. …”
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Local Pyramid Vision Transformer: Millimeter-Wave Radar Gesture Recognition Based on Transformer with Integrated Local and Global Awareness by Zhaocheng Wang, Guangxuan Hu, Shuo Zhao, Ruonan Wang, Hailong Kang, Feng Luo

“…A millimeter-wave radar is widely accepted by the public due to its low susceptibility to interference, such as changes in light, and the protection of personal privacy. …”
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Interaction of integrin αvβ3 and fibronectin under fluid shear forces: implications for tumor cell adhesion and migration by Paimin Zhuo, Quhuan Li, Bishan Yang, Bishan Yang, Na Li, Zhiqing Luo, Fengxia Zhang

“…The interaction between integrin αvβ3 and fibronectin enables tumor cell adherence to endothelial layers under diverse hydrodynamic blood flow conditions, particularly in low shear stress regions. Understanding the mechanical binding characteristics between integrin αvβ3 and fibronectin under different hydrodynamic environments can provide insights into tumor cell invasion and proliferation. …”
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Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study. by Nicole Young, Miriam Taegtmeyer, George Aol, Godfrey M Bigogo, Penelope A Phillips-Howard, Jenny Hill, Kayla F Laserson, Feiko Ter Kuile, Meghna Desai

“…This is particularly evident at rural dispensaries that lack laboratories and have parallel programmes for HIV, reproductive health and malaria, resulting in fractured and inadequate care for women.…”
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A wave-resolving two-dimensional vertical Lagrangian approach to model microplastic transport in nearshore waters based on TrackMPD 3.0 by I. Jalón-Rojas, D. Sous, D. Sous, V. Marieu

“…High-density microplastics moved onshore near the bed, accumulating in proximity to the wave-breaking zone, while the distribution of low-density particles varied along the coastal profile depending on the particle properties. …”
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MDMU-Net: 3D multi-dimensional decoupled multi-scale U-Net for pancreatic cancer segmentation by Lian Lu, Miao Wu, Gan Sen, Fei Ren, Tao Hu

“…However, due to the variable morphology, blurred boundaries, and low contrast with surrounding tissues in CT images, traditional manual segmentation methods are inefficient and heavily reliant on expert experience. …”
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Modeling of binary nanooxides with solid solutions and mixed phases by V. M. Gun’ko

“…Therefore, in this study, two semiempirical methods (PM7 and DFTB+ used in semiempirical packages (MOPAC, DFTB+) and implemented in the most known packages such as Gaussian, GAMESS, AMS, etc.) have been used in parallel to DFT (mainly ?B97X-D/cc-pVDZ) to compute various clusters (22, 35, 88, 94, and 111 units) with silica, alumina, titania, titania/silica, and alumina/silica. …”
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Rapid Quantitative Detection of Dye Concentration in Pt/TiO₂ Photocatalytic System Based on RGB Sensing by Cuiyan Han, Ziao Wang, Jiahong Cui, Shuqi Liu, Liu Yang, Yang Fu, Baolin Zhu, Cheng Guo

“…This article presents an integrated strategy that couples high-efficiency photocatalytic degradation with low-cost, rapid detection to overcome the main drawbacks of conventional TiO₂-based photocatalysts, including a weak visible-light response, rapid charge–carrier recombination, and reliance on expensive instrumentation for dye concentration detection. …”
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Diversité de la flore ligneuse à la périphérie du Parc national de Waza (Cameroun) by Evaliste Remi Jiagho, Louis Zapfack, Louis Paul Roger Kabelong Banoho, Moise Tsayem-Demaze, Jeannine Corbonnois, Paul Tchawa

“…The experimental research carried out consists of transects with variable sizes, horizontal, parallel and equidistant. Data collection was made on 23 transects, with a sampling rate of 0.8 %. …”
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Multi-modal denoised data-driven milling chatter detection using an optimized hybrid neural network architecture by Haining Gao, Haoyu Wang, Hongdan Shen, Shule Xing, Yong Yang, Yinlin Wang, Wenfu Liu, Lei Yu, Mazhar Ali, Imran Ali Khan

“…A hybrid neural network model (DBMA) for chatter detection is constructed by integrating dual-scale parallel convolutional neural networks, bidirectional gated recurrent units, and multi-head attention mechanisms. …”
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Impact of personalised feedback about physical activity on change in objectively measured physical activity (the FAB study): a randomised controlled trial. by Job G Godino, Clare Watkinson, Kirsten Corder, Theresa M Marteau, Stephen Sutton, Stephen J Sharp, Simon J Griffin, Esther M F van Sluijs

“…<h4>Background</h4>Low levels of physical activity are a major public health concern, and interventions to promote physical activity have had limited success. …”
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Simulation and assessment of the risk of carbon sink loss in Hubei Province, China by Jiang Li, Jiang Li, Baomiao Ning, Rui Shu, Rui Shu, Yixiong Xia, Guobin Yuan, Yun Shen, Yanping Yu, Xun Liang

“…Current studies face challenges of low resolution and difficulties in fine-scale simulations.MethodThis study developed a novel large-scale, high-resolution approach for estimating and simulating carbon sinks and storage changes based on the PLUS model, incorporating cropland and grassland management practices' effects on soil organic carbon, and utilizing block parallel computing.Results and discussionResults show that from 2020 to 2030 and 2060, Hubei Province's croplands and construction lands are the main land types undergoing transition while forestlands steadily increase. …”
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Experimental observations of bifurcated power decay lengths in the near Scrape-Off Layer of ST40 High Field Spherical Tokamak by X. Zhang, C. Marsden, M. Moscheni, E.N.J. Maartensson, A. Rengle, M. Robinson, T. O’Gorman, H.F. Lowe, E. Vekshina, S. Janhunen, A. Scarabosio, P.F. Buxton, M. Sertoli, M. Romanelli, S.A.M. McNamara, T.K. Gray, N.A. Lopez

“…The scrape-off layer parallel heat flux decay lengths measured at ST40, a high field, low aspect ratio spherical tokamak, have been observed to bifurcate into two groups. …”
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MUC1, MUC2, MUC4, MUC5AC, Cdx2: immunohistochemical characteristics in polyps and adenocarcinoma of distal colon by M. A. Shyshkin

“…Distal colonic carcinoma has extremely low median of MUC2 expression. The highest levels of MUC4 expression are observed in hyperplastic polyps, somewhat lower – in unchanged mucosa. …”
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Improving transparency in malaria programme funds: A business case for connected diagnostics in Kenya by Charlotte M. Dieteren, Emmanuel Milimo, Angela Siteyi, Shannen van Duijn, Leon Stijvers, Lilyana Dayo, Gregory Ganda, Tobias F. Rinke de Wit

“…Background: International vertical health financing programmes risk functioning in parallel with existing domestic funding in low- and middle-income countries (LMICs), leading to inefficient service delivery and concomitant poor health outcomes. …”
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Comparison of Radiographic Parameters Used to Assess Haglund Deformities in an Asian Population: A Case–Control Study by Fu Yuen Thong, Tanawat Vaseenon, Theenesh Theyvan, Pawee Chalidapong, Jirawat Saengsin

“…The HPPPL exhibited a notable disparity in the symptomatic group but demonstrated low specificity and positive predictive value (PPV). …”
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Plant Height Estimation in Corn Fields Based on Column Space Segmentation Algorithm by Huazhe Zhang, Nian Liu, Juan Xia, Lejun Chen, Shengde Chen

“…Addressing these issues through algorithm optimization, parallel processing, and the integration of additional data sources such as multispectral or LiDAR data could enhance its scalability and robustness. …”
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Quantifying Thermal Demand in Public Space: A Pedestrian-Weighted Model for Outdoor Thermal Comfort Design by Deyin Zhang, Gang Liu, Kaifa Kang, Xin Chen, Shu Sun, Yongxin Xie, Borong Lin

“…For example, in a sidewalk area parallel to the main street, several points exhibited high discomfort levels (HI = 0.95) but low pedestrian volume, resulting in DTC values approximately 0.2 units lower than adjacent zones with lower discomfort levels (HI = 0.7) but higher foot traffic. …”
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