Comparative effectiveness and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in patients with HBV-associated decompensated cirrhosis: insights from a retrospe... by Lu Chen, Hui-Fang Zhang, Yi-Jing Cai, Lei Zhang, Chao Cai, Ming-Qin Lu, Yue-Ying Zhu

“…Given the severity of decompensated cirrhosis, selecting the most appropriate first-line antiviral medication is crucial for optimizing treatment outcomes and providing the best possible disease control. …”
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CD66b⁺ Tumor-Infiltrating Neutrophil-like Monocytes as Potential Biomarkers for Clinical Decision-Making in Thyroid Cancer by Hamdullah Yanik, Ilgin Demir, Ertugrul Celik, Ece Tavukcuoglu, Ibrahim Burak Bahcecioglu, Adile Begum Bahcecioglu, Mehmet Mert Hidiroglu, Sumeyra Guler, Nese Ersoz Gulcelik, Mehmet Ali Gulcelik, Kerim Bora Yilmaz, Gunes Esendagli

“…Accordingly, these cells were more frequently detected in tumor tissues (21.1 ± 2.1% of total tumor-infiltrating immune cells) compared to non-tumor thyroid tissues (<i>p</i> = 0.0231). …”
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Mediating role of psychological resilience between depression and humoral immunological biomarkers in medical staff by Yunyun MA, Yanshuan WEI, Lili QIAN, Xiufeng ZUO, Dechao WANG, Shanfa YU

“…Serum immunoglobulin (Ig) M (IgM), IgG, IgA, complement 3 (C3), and complement 4 (C4) were detected in fasting venous blood samples. Mann-Whitney U test, Kruskal-Wallis H test, independent-samples t-test, and One-way ANOVA were used for comparisons among different demographic groups. …”
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Characterizing Patient-Reported Fatigue Using Electronic Diaries in Neurodegenerative and Immune-Mediated Inflammatory Diseases: Observational Study by Adrien Bennetot, Rana Zia Ur Rehman, Robbin Romijnders, Zhi Li, Victoria Macrae, Kristen Davies, Wan-Fai Ng, Walter Maetzler, Jennifer Kudelka, Hanna Hildesheim, Kirsten Emmert, Emma Paulides, C Janneke van der Woude, Ralf Reilmann, Svenja Aufenberg, Meenakshi Chatterjee, Nikolay V Manyakov, Clémence Pinaud, Stefan Avey

“…Future research should explore optimized eDiary protocols to balance participant burden with data granularity.…”
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Psychopathological Comorbidities in Children and Adolescents with Feeding and Eating Disorders: An Italian Clinical Study by Maria Califano, Jacopo Pruccoli, Oliviero Cavallino, Alessandra Lenzi, Antonia Parmeggiani

“…Future research should further investigate these transdiagnostic mechanisms to optimize clinical care.…”
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10-YEARS ANALYSIS OF CRYOBAG FRACTURE IN A LARGE INVENTORY OF CELLULAR THERAPY PRODUCTS: RATES AND RISK FACTORS by AR Belisário, LT Mendonça, RK Andrade, MC Martins, LA Costa, KL Prata

“…These insights underscore the importance of monitoring and optimizing both TNC and hematocrit levels during the preparation of cellular therapy products. …”
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Novel perceptions and insights into the rare hematologic malignancy of acute megakaryocytic leukemia: a multicenter clinical retrospective study by Yuan Liu, Yanquan Liu, Xiaojun Chen, Yue Yin, Zhenyuan Xu, Jiachen Xie, Jianzhen Shen, He Huang, Huidong Guo

“…Except for 2 patients who were not detected by flow immunotyping, cytogenetics and molecular biology, the remaining 21 patients were detected accordingly, and megakaryocyte antigens (CD41, CD42, CD61) were expressed in these 21 patients with AMKL, accompanied by certain cytogenetic or molecular biological abnormalities. …”
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Mechanism of electroacupuncture on rats with primary dysmenorrhea based on microRNA expression spectrum and PI3K/Akt/mTOR signaling pathway by Si-an PAN, Shao-hua WANG, Han-yu YUAN, Juan LI, Xiao XUE, Zeng-hui YUE, Yu LIU

“…After the 10-day intervention, samples were collected and transmission electron microscopy was used to observe the ultrastructural changes of the cells in uterine tissue in each group. With RNA-seq method, the changes of miRNA expression spectrum in rat uterine tissue were detected. …”
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Chronic lymphocytic leukemia in combination with COVID-19: clinical features and unfavorable prognosis factors by O. L. Kochneva, E. A. Baryakh, E. N. Misyurina, E. I. Zhelnova, K. V. Yatskov, T. S. Chudnova, Yu. Yu. Polyakov, A. B. Makeshova, M. A. Mingalimov, D. D. Ivanova, L. T. Shimanovskaya, E. N. Zotina, T. N. Tolstykh, E. Yu. Grishina, D. E. Gagloeva, V. N. Yakimets, A. I. Koneva, E. A. Karimova

“…To identify risk factors for hospital mortality and severe course of COVID-19, as well as to optimize therapeutic and preventive measures.Materials and methods. …”
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Phenotypic and Genotypic Characterization of ESBL-, AmpC-, and Carbapenemase-Producing <i>Klebsiella pneumoniae</i> and High-Risk <i>Escherichia coli</i> CC131, with the First Repo... by Hajer Ziadi, Fadela Chougrani, Abderrahim Cheriguene, Leticia Carballeira, Vanesa García, Azucena Mora

“…Fluoroquinolone resistance (FQR) was detected in 94.1% of <i>K. pneumoniae</i> isolates. …”
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Captura de movimiento y reconocimiento de actividades para múltiples personas mediante un enfoque bayesiano by A. Marcos, D. Pizarro, M. Marrón, M. Mazo

“…The resulting hypotheses, automatically selected from the particle distribution, are then refined using non-linear optimization methods with statistical priors. The whole framework is tested using a simple but standard method based on comparing articulated cylindrical models with SfS volumes, taken from several cameras. …”
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Hemodynamic effects of adjunct arginine vasopressin to norepinephrine in septic shock: insights from a prospective multicenter registry study by Max Melchers, Vivienne de Smet, Chrissie Rooijakkers, Jonathan Huising, Wander Vermeulen, Beyza Nur Nisa Köktaş, Karlijn Johanna van de Vusse, Kimia Milani Sabzewar, Shakti Bedanta Mishra, Carina Bethlehem, Dirk P. Boer, Nedim Cimic, Mirella van Duijnhoven, Tim Frenzel, Jordi Liesveld, Gianluca Paternoster, Susanne Stads, Jan J. Weenink, Barbara Festen-Spanjer, Peter Pickkers, Arthur Raymond Hubert van Zanten

“…Univariate and multivariable regression analyses were performed to detect associations between characteristics and outcomes. …”
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Rapid laboratory confirmation of the 2025 Sudan Virus Disease (Svd) index case in Uganda by Andrew Nsawotebba, Susan Nabadda, Valeria Nakintu, Isaac Ssewanyana, Misaki Wayengera, Jonathan Kabazzi, Stephen Balinandi, Godfrey Pimundu, Tonny Muyigi, Alisen Ayitewala, Samuel Gidudu, Morgan Otita, Ibrahim Mugerwa, Moses Rubangakene, Sulaiman Ikoba, Sam Kalungi, Rhoda Wanyenze, Kevin K. Ariën, Eunice Namboozo, Benedict Kanamwanji, Steven Ssekyondwa, Ronald Kasujja, Derrick Kitwe, Catherine Dambya, Innocent Morunyanga, Reginald Rony Bahatungire, Francis Kakooza, Moses Joloba, Atek Kagirita, Allan Muruta, Pontiano Kaleebu, Henry Kyobe, Charles Olaro, Diana Atwine, Jane Ruth Aceng

“…Comprehensive VHFs panel testing is crucial for detecting pathogens in suspected cases. Sample dilution impacts diagnostic sensitivity, making optimized testing protocols crucial for precise molecular diagnostics. …”
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Regional patterns of genetic variants in expanded carrier screening: a next-generation sequencing pilot study in Fujian Province, China by Danhua Guo, Danhua Guo, Nani Zhou, Qianqian He, Qianqian He, Na Lin, Na Lin, Shuqiong He, Shuqiong He, Deqin He, Deqin He, Yifang Dai, Yifang Dai, Ying Li, Ying Li, Xuemei Chen, Xuemei Chen, Hailong Huang, Hailong Huang, Jia Jia, Hua Cao, Liangpu Xu, Liangpu Xu

“…However, before integrating ECS into regional public health initiatives, the development of a region-specific, curated disease panel is necessary to optimize screening efficacy and clinical utility.…”
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Hand hygiene versus additional non-sterile gloves and gowns use to prevent sepsis in preterm infants colonized with multi-resistant drug bacteria: the study protocol of the cluster... by Kirstin Faust, Clara Haug, Julia Pagel, Reinhard Jensen, Anja Stein, Ursula Felderhoff-Müser, David Frommhold, Kirsten Brebach, Christian Wieg, Georg Hillebrand, Barbara Naust, Esther Schmidt, Lutz Koch, Susanne Schmidtke, Arne Simon, Michael Zemlin, Sascha Meyer, Christopher Scholzen, Natascha Köstlin-Gille, Christian Gille, Ann-Carolin Longardt, Manuela Kärlin, Mirjam Lusga, Wolfgang Göpel, Manuel Krone, Stefanie Kampmeier, Franziska Strecker, Dennis Nurjadi, Inke R. König, Egbert Herting, Jan Rupp, Christoph Härtel

“…Therefore, it is an urgent need to optimize and evaluate infection prevention and control (IPC) strategies. …”
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Antibody response after SARS-CoV-2 infection or vaccination in China: A cross-sectional study by Peng Zhu, Yan Chen, Xia Xu, Deyong Tan, Ledong Xiao, Chengling Liao, Huan Xia, Ting Zhang, Jing Zou, Xuan Chen, Man Li, Yang Yang, Jian Zhou, Jia Liu, Wei Zhang, Honghao Zhou, Qing Li

“…Conclusions: It is highly essential to optimize vaccination protocols in practice settings and develop future vaccines that offer a broader spectrum of protection.…”
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Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…There is a large amount of uncertainty about optimal treatment for AN particularly for the subgroup with a protracted and severe form of illness admitted for inpatient/day patient care. …”
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Relationship between Patterned Grounds Evolutions and Spatial and Temporal Changes in the Chemical Compounds of SAHL ABAD Playa Salt Flats (Case Study: Khorasan province) by Mahdi Saghafi

“…Therefore, we can assess the relationship between the effective variables in the Playa expansion process, and given the fact that the process of satellite imaging is a sequential process, one can create relationships in previous studies in a region and with the advancements in technology, it instantly optimized. …”
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Effects of Visual and Lateral Line Organs on Reefing Behavior of Sebastes schlegelii by Feng CHEN, Jiao LI, Pihai GONG, Changtao GUAN

“…Vision and the lateral line system are particularly important for detecting environmental features and predators among the primary sensory modalities. …”
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Nonlinear Relationship Between the Elderly’s Perception of Green Spaces and Their Activity Characteristics by Yuanjing WU, Yongyi YOU, Wei ZHOU, Siren LAN

“…Despite limitations in sample coverage and cross-sectional design, this research provides valuable insights and empirical evidence for optimizing the design and renovation of age-friendly parks. …”
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