The role of supine imaging in assessing failure of pelvic compensation and its impact on surgical outcomes in patients with adult spinal deformity by Dongfan Wang, Wei Wang, Yu Wang, Chao Kong, Shuaikang Wang, Xiaolong Chen, Shibao Lu

“…Based on the calculated minimum detectable change of SS, FPC was defined as the change in SS of less than 3.9° between supine and upright positions. …”
Get full text

Transforming apricot kernel shell into a multifunctional photocatalyst for wastewater treatment and antimicrobial applications by Faqin Lian, Fareena Batool, Muzammil Anjum, Samia Qadeer, Abubakr M. Idris, Waqar-un- Nisa, Zepeng Rao, Zepeng Rao, Habib Ullah

“…Among various industries, pharmaceutical compounds have been detected in various aquatic environments and food supply chains; therefore, they need an economical and efficient treatment process. …”
Get full text

Predictive Value of Varicocele Grade and Histopathology in Simultaneous Varicocelectomy and Sperm Retrieval in Non-Obstructive Azoospermia: A Retrospective Cohort Study by Aris Kaltsas, Fotios Dimitriadis, Michael Chrisofos, Nikolaos Sofikitis, Athanasios Zachariou

“…These findings provide valuable insights for optimizing fertility treatments in men with NOA undergoing varicocele repair.…”
Get full text

Novel Classification of Peroneal Tendon Disease Reveals Cellular and Molecular Phenotypes of the Tenosvnovium by Julia Matthias MD, Michael A. David PhD, Sara E. Buckley DO, Daniel J. Ross MD, Nathaniel Zona BA, Michael A. Hewitt B.A., Joshua Metzl MD, Daniel K. Moon MD, MS, MBA, Courtney Grimsrud MD, Douglas J. Adams PhD, Michael Zuscik PhD, Kenneth Hunt MD

“…Kruskal Wallis with Dunn’s post-hoc was used to detect differences in cellular density between PTD1-4 vs PTD0. …”
Get full text

Infections and antibiotic resistance in Malawian children 6-59 months old hospitalized with severe acute malnutrition by Dr Bryan Vonasek, Ms. Mwawi Nyirongo, Mr. Alexander Kondwani, Dr. Anthony Garcia-Prats, Ms. Tiwonge Kamvaunamwali, Ms. Doris Ng'oma, Mr. James Kaphatika, Mr. Amazing-Grace Tepeka, Dr. Mercy Kumwenda, Dr. Emily Ciccone, Dr. Tisungane Mvalo

“…Tuberculosis disease (TB) was diagnosed in 9% and was also associated with mortality (OR: 3.4, 95% CI: 1.1-10.4). Blood cultures detected likely pathogens for 10% of participants. …”
Get full text

Mutation-based, neoadjuvant treatment for advanced anaplastic thyroid carcinoma by Sabine Wächter, Detlef K. Bartsch, J. Riera Knorrenschild, Anika Pehl, Friederike Eilsberger, Andreas Pfestroff, Markus Luster, Katharina Holzer, Andreas Neubauer, Elisabeth Maurer

“…This study aimed to investigate whether mutation-based neoadjuvant therapy can convert an initially unresectable tumor into a resectable state, optimizing local tumor control and prolonging overall survival.MethodsPatients with stages IVB and limited IVC BRAFV600E-negative ATC received immediate combination therapy consisting of the multikinase inhibitor (mKI) lenvatinib and the immune checkpoint inhibitor (ICI) pembrolizumab upon diagnosis. …”
Get full text

AI-HOPE-TGFbeta: A Conversational AI Agent for Integrative Clinical and Genomic Analysis of TGF-β Pathway Alterations in Colorectal Cancer to Advance Precision Medicine by Ei-Wen Yang, Brigette Waldrup, Enrique Velazquez-Villarreal

“…These findings underscore the platform’s capacity to detect both known and emerging clinical–genomic patterns in CRC. …”
Get full text

Does Syndesmotic Fixation Technique Impact Complication Rates and Functional Outcomes Measured by PROMIS Scores Following Operative Repair of Ankle Fractures? by Steven Hadley BA, Rachel Bergman MD, John Peabody MD, Sarah Westvold MPH, Ryan Filler MD, Milap Patel DO, Anish Kadakia MD

“…Analysis of PROMIS scores had 80% power to detect large effect sizes (Cohen’s f = 0.40) with a 0.05 significance level but was underpowered for small and medium effects. …”
Get full text

Identifying nontuberculous mycobacteria from a mycobacteria growth indicator tube with nuclear magnetic resonance spectroscopy: A laboratory metabolomics analysis case report by Dr Christoffel Opperman, Dr Marwaan Rylands, Dr Sarishna Singh, Ms Aysha Amien, Mr Yonas Ghebrekristos, Prof Rob Warren, Dr Wynand Goosen

“…However, the complexity of MGIT broth media presents challenges for NMR-based NTM identification, necessitating optimization of sample preparation methods. Therefore, in light of the growing demand for improved NTM diagnostic tools, this laboratory case accentuates the need to contemplate innovative approaches with cutting-edge technology for NTM identification.…”
Get full text

Influence of Fermentation of Eurotium cristation on the Flavor Characteristics of Guizhou White Tea by Jinlong LUO, Zhongying LIU, Shimao FANG, Tuo ZHANG, Yuqiao DAI, Xiaowei YANG, Ting YANG, Mengzhen ZHU, Qiang SHEN

“…A total of 74 aroma substances were detected in WT and ECWT, of which 62 were key differential aroma substances and 49 were detected in WT. …”
Get full text

Balancing accuracy and user satisfaction: the role of prompt engineering in AI-driven healthcare solutions by Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Peijin Zeng, Peijin Zeng, Peijin Zeng, Xinyue Li, Kelvin Kam-Lung Chong, Guanghui Hou, Xiaoxiao Fang, Yang Yu, Xiangrong Yu, Junbin Fang, Yi Pan

“…This study explores the application of IoT-enabled, AI-driven systems for detecting and managing Dry Eye Disease (DED), emphasizing the use of prompt engineering to enhance system performance.MethodsA specialized prompt mechanism was developed utilizing OpenAI GPT-4.0 and ERNIE Bot-4.0 APIs to assess the urgency of medical attention based on 5,747 simulated patient complaints. …”
Get full text

Impact of respiratory syncytial virus on Streptococcus pneumoniae resistance to β-lactam antibiotics: an investigative study in children by Lu Li, Yushun Wan, Yuncheng Wang, Ye Tao, Xiao Long, Enmei Liu, Yu Deng

“…Retrospective data showed elevated penicillin resistance in RSV + S.pn co-detections vs. S.pn alone during 2012 (2.8% vs. 40.9%), 2017 (2.8% vs. 30.4%), and 2018 (6.2% vs. 38.6%) (all p < 0.001). …”
Get full text

Enhancing Cardiovascular Risk Prediction with a Simplified Carotid IMT Protocol: Evidence from the IMPROVE Study by Fabrizio Veglia, Anna Maria Malagoni, Mauro Amato, Rona J. Strawbridge, Kai Savonen, Philippe Giral, Antonio Gallo, Matteo Pirro, Bruna Gigante, Per Eriksson, Douwe J. Mulder, Beatrice Frigerio, Daniela Sansaro, Alessio Ravani, Daniela Coggi, Roberta Baetta, Nicolò Capra, Elena Tremoli, Damiano Baldassarre

“…<b>Methods</b>: CIMT was measured in 3165 subjects from six centers, in five European countries, belonging to the IMPROVE study. …”
Get full text

Comprehensive Risk Assessment of LAD Disease Progression in CCTA: The CLAP Score Study by Antonella Tommasino, Federico Dell’Aquila, Marco Redivo, Luca Pittorino, Giulia Mattaroccia, Federica Tempestini, Stefano Santucci, Matteo Casenghi, Francesca Giovannelli, Stefano Rigattieri, Andrea Berni, Emanuele Barbato

“…Results: severe proximal LAD stenosis was detected in 32% (160/499) of patients by CCTA. MACE occurred in 12.5% of patients at follow-up. …”
Get full text

Diagnostic Efficacy of Staging Laparoscopy Compared to CT and PET-CT in Gastric Cancer: A Retrospective Cohort Analysis by Cem Batuhan Ofluoğlu, Isa Caner Aydın, Fırat Mülküt, Orhan Uzun, Aziz Serkan Senger, Selçuk Gülmez, Uğur Duman, Erdal Polat, Mustafa Duman

“…<i>Conclusions</i>: SL provides superior diagnostic accuracy and prognostic information for advanced gastric cancer staging compared with CT and PET-CT. By accurately detecting peritoneal metastasis, SL aids in optimizing treatment plans, particularly in advanced stages, thus potentially improving patient outcomes.…”
Get full text

The association between physician sex and patient outcomes: a systematic review and meta-analysis by Kiyan Heybati, Ashton Chang, Hodan Mohamud, Raj Satkunasivam, Natalie Coburn, Arghavan Salles, Yusuke Tsugawa, Ryo Ikesu, Natsumi Saka, Allan S. Detsky, Dennis T. Ko, Heather Ross, Mamas A. Mamas, Angela Jerath, Christopher J. D. Wallis

“…There is a paucity of pooled evidence examining the association of physician sex with clinical outcomes. Methods This random-effects meta-analysis was conducted according to the PRISMA guidelines and prospectively registered on PROSPERO. …”
Get full text

Current <i>Streptococcus Pneumoniae</i> Serotypes in Sverdlovsk Region in 2020–2021 by E. V. Bolgarova, Yu. A. Zakharova, I. S. Mukhachev, I. A. Korotkova, I. A. Ivashchenko, А. V. Ostapchuk, O. I. Mamontov

“…In the individuals of the studied groups of observation, in 27.0% and 28.1% of the cases the study detected the S. pneumoniae in the biological material with circulation of 12 «vaccine» (19F – 2,6%, 6ABCD – 2,6%, 4 – 2,0%, 23F – 2,0%, 9AV – 1,3%, 9LN – 0,6%, 11AD – 1,3%, 18ABCF – 2,0%) and «nonvaccine» (15AF – 0.7%, 16F – 0.6%) serotypes. …”
Get full text

Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness by Nan Wang, Nan Wang, Nan Wang, Yifang He, Sipeng Zhu, Dongsheng Liu, Xiaoke Chai, Xiaoke Chai, Qiheng He, Tianqing Cao, Jianghong He, Jingqi Li, Juanning Si, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Yi Yang, Jizong Zhao, Jizong Zhao

“…By providing real-time feedback on cortical activation, fNIRS facilitates optimizing therapeutic strategies and supports individualized treatment planning. …”
Get full text

Classifying Dry Eye Disease Patients from Healthy Controls Using Machine Learning and Metabolomics Data by Sajad Amouei Sheshkal, Morten Gundersen, Michael Alexander Riegler, Øygunn Aass Utheim, Kjell Gunnar Gundersen, Helge Rootwelt, Katja Benedikte Prestø Elgstøen, Hugo Lewi Hammer

“…Clinical signs and symptoms are currently used to diagnose dry eye disease. Metabolomics, a method for analyzing biological systems, has been found helpful in identifying distinct metabolites in patients and in detecting metabolic profiles that may indicate dry eye disease at early stages. …”
Get full text

Improving pain, function and quality of life in end-stage knee osteoarthritis: a patient-preference cohort study on whole-body vibration and exercise as bridging therapies for tota... by Kendrew Yu-Hei Choi, Wai-Wang Chau, Linda Man-Kuen Li, Sammie Yuk-Lam Ng, Boie Po-Yee Lo, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

“…Minimal Clinically Important Difference (MCID) and Minimal Detectable Change (MDC) were calculated to assess the clinical significance of the results. …”
Get full text