SARS-CoV-2 N protein and anti-spike serologies: insights into COVID-19 disease severity and mortality—a secondary analysis of the ACTIV-1 trial by Alfredo J. Mena Lora, Kimi Enders, Huimin Wu, Luis Parra-Rodriguez, Christopher Palma, Katy Saliba, Sylvain Laverdurre, P Brian Smith, Kevin J. Anstrom, Samuel A. Bozzette, William G. Powderly

“…Further research is needed to explore the clinical implications of these findings to optimize patient care and enhance outcomes.…”
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An Informer-based multi-scale model that fuses memory factors and wavelet denoising for tidal prediction by Peng Lu, Yuchen He, Wenhui Li, Yuze Chen, Ru Kong, Teng Wang

“…We combined integrated frequency domain optimization and multi-level, multi-scale convolutional kernel technologies. …”
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Thrombotic adverse events associated with TNF-alpha blockers: a real-world pharmacovigilance analysis of the FAERS database by Lijuan Song, Nan Yang, Xinglong Xing, Yicong Zhao, Jingkai Di

“…This study offers valuable insights for optimizing treatment and improving safety.…”
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Transcriptomic features of immune inflammation and neural plasticity associated with early neurological improvement in acute ischemic stroke patients with large vessel occlusion by Dong Zhang, Xinying Jing, Ruinan Ma, Zhizhang Li, Xiaoguang Zhang, Ying Ding, Yunhua Yue

“…This study aims to investigate the peripheral blood mRNA molecular characteristics and underlying mechanisms associated with ENI after EVT in AIS-LVO patients, to inform individualized treatment and optimize prognosis.MethodsThis retrospective study included AIS-LVO patients who underwent EVT between January 2022 and December 2023. …”
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Microplastics in Museums: Pollution and Paleoecology by Christine C. Gaylarde, Estefan M. da Fonseca

“…Such research studies, and potential similar investigations on historical stored tissue samples, require optimization before the information stored in these sources can be fully mined. …”
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Post-endoscopic retrograde cholangiopancreatography cholangitis after endoscopic treatment of post-transplant biliary strictures: a retrospective study by Chengcheng Christine Zhang, Ronald Koschny, Christian Rupp, Patrick Michl, Arianeb Mehrabi, Cyrill Wehling, Marcus Kantowski, Peter Sauer

“…Since the success rate of endoscopic intervention in these complex strictures is limited, an optimized peri-interventional management and tailored antibiotic therapy may become particularly important for the further treatment and prognosis of these patients.…”
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Elderly patients undergoing laparoscopic radical cystectomy benefit from dynamic D-dimer measurement in combination with vascular ultrasonography: reduction of VTE risk and improve... by Wenbo Gao, Haihong Ye, Yangkai Xu

“…In EG, dynamic D-dimer measurements revealed a distinct temporal declining pattern. In HCG, VTE was detected in five patients out of 98 patients (5/98, 4.08%); and in EG, eight patients were found to have DVT (8/109, 7.34%; p = 0.04). …”
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Sports injury and illness incidence at the 2021 Summer Universiade: a retrospective study of 6,500 athletes from 113 countries/regions by Zhiwei Li, Shiyun Li, Zhigang Liu, Shunchang Li, Huang Huang, Tutu Wang, Geping Wang

“…ObjectiveTo provide insights and recommendations for athletes, medical personnel, and event organizers on optimize healthcare services and preventive measures for injuries and illnesses by describing the pattern of injuries and illnesses sustained during the 2021 Summer World University Games.MethodsMedical records of athletes visiting Universiade Athletes’ Village Polyclinic from July 22 to August 10, 2023, were anonymously analyzed to describe the injuries and illnesses sustained.ResultsA total of 478 athletes visited the clinic, including 315 injuries and 163 illnesses. …”
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Distribution of Minimum Inhibitory Concentrations and Resistance-associated Gene Mutations in Multidrug-resistant Mycobacterium tuberculosis Strains from Southern Türkiye: Insights... by Huda Ahmed, Hamdi Gokahmetoglu, Gulfer Yakici, Fatih Koksal

“…METHODS: MICs and gene mutations were evaluated for BDQ, DEL, and LZD. …”
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Identifying behavior regulatory leverage over mental disorders transcriptomic network hubs toward lifestyle-dependent psychiatric drugs repurposing by Mennatullah Abdelzaher Turky, Ibrahim Youssef, Azza El Amir

“…As food choices and daily habits play a fundamental role in this fluctuation, integrating machine learning with network medicine can provide valuable insights into disease systems and the regulatory leverage of lifestyle in mental health. Methods This study analyzed coexpression network modules of MDD and PTSD blood transcriptomic profile using modularity optimization method, the first runner-up of Disease Module Identification DREAM challenge. …”
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Greenness, blueness, and whiteness evaluation of a quantitative nuclear magnetic resonance procedure for concurrent assay of aspirin and omeprazole in their single and fixed-dose c... by Amal A. El-Masry, Abdallah M. Zeid, Nora A. Abdallah

“…The detecting and quantifying limits for both drugs were approximately 0.01 and 0.03 mg mL−1, respectively. …”
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Quantitation of Cannabidiol (CBD) in brain regions and plasma following intranasal administration of a CBD nanoformulation by Gunjan Upadhyay, Oksana Fihurka, Pranav Patel, Juan Sanchez-Ramos

“…Intranasal (IN) nanoparticle delivery may enhance the bioavailability of lipophilic cannabidiol (CBD), addressing limitations associated with systemic administration. Methods Further optimization of nanoparticle properties is necessary to enhance brain uptake and therapeutic potential for neurological disorders. …”
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Explainable artificial intelligence with UNet based segmentation and Bayesian machine learning for classification of brain tumors using MRI images by K. Lakshmi, Sibi Amaran, G. Subbulakshmi, S. Padmini, Gyanenedra Prasad Joshi, Woong Cho

“…Abstract Detecting brain tumours (BT) early improves treatment possibilities and increases patient survival rates. …”
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The impact of baseline laboratory tests on the management of new-onset hypertension in primary care: A pilot study. by Katia Kteich, Maria R Karam, Marouan Zoghbi, Mabel Aoun

“…Our findings support the use of baseline laboratory testing in order to optimize blood pressure control and individual patient management.…”
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The impact of adenomyosis on intrauterine insemination success in unexplained infertile women: a retrospective cross-sectional study by Sefa Arlıer, Sadık Kükrer, Fikriye Işıl Adıgüzel, Ahmet Zeki Nessar, Gülsüm Uysal, Cevdet Adıgüzel, Dilek Kaya Kaplanoğlu

“…Routine assessment of adenomyosis should be considered in infertility evaluations to optimize clinical management and treatment success.…”
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Changing snow conditions are challenging moose (Alces alces) surveys in Alaska by Todd J. Brinkman, Kalin A. Kellie, Adele K. Reinking, Glen E. Liston, Natalie T. Boelman

“…Complete snow cover is required to reliably detect and count moose using visual observation from an aircraft. …”
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Comparative Effects of Intermittent vs. Constant Ceftiofur Hydrochloride Exposure on <i>Staphylococcus aureus</i> In Vitro by Junli Wang, Chongyang Li, Fanxi Guo, Zugong Yu

“…This study aims to explore how different concentrations, durations, and dosing frequencies affect susceptibility and bactericidal efficacy of <i>Staphylococcus aureus</i> to optimize CEF dosage regimens. Methods: First, CEF was intermittently administered at 1/2 × minimum inhibitory concentration (MIC), 2 × MIC, 6 × MIC, and 100 × MIC for 30 cycles. …”
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Multi-Global Navigation Satellite System for Earth Observation: Recent Developments and New Progress by Shuanggen Jin, Xuyang Meng, Gino Dardanelli, Yunlong Zhu

“…Ten-minute water level change with centimeter-level accuracy was estimated with ground-based multiple GNSS-R data based on a weighted iterative least-squares method. Furthermore, a cyclone and its positions were detected by utilizing the GNSS-reflectometry from the space-borne Cyclone GNSS (CYGNSS) mission. …”
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Cardiovascular and Metabolic Adverse Events of Endocrine Therapies in Women with Breast Cancer: A Disproportionality Analysis of Reports in the FDA Adverse Event Reporting System by Shaimaa Elshafie, Lorenzo Villa‐Zapata, Randall L. Tackett, Iman Y. Zaghloul, Henry N. Young

“…Descriptive and disproportionality analyses were performed to assess reports and detect safety signals. Results Among 14,327 unique ET‐related reports, arthralgia (n = 1873 events) was the most prevalent reaction. …”
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Generation of bovine iPSCs from fetal fibroblasts for in vitro myogenesis and cultured meat by Kaiana Recchia, Methi Wathikthinnakon, Fabiana Fernandes Bressan, Fabiana Fernandes Bressan, Kristine Freude

“…While promising, the study also highlights the difficulty in achieving complete myogenic differentiation, indicating a need for further optimization of differentiation protocols.…”
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