Prognostic model of rapid hepatic fibrosis progression in men with chronic hepatitis C by T. I. Koval, L. M. Syzova, H. M. Dubynska, N. O. Pryimenko, S. S. Rudenko

“…The aim of the research was to determine clinical and genetic predictors and to create a prognostic model for the rapid hepatic fibrosis progression in men with chronic hepatitis C. Materials and methods. А cross-sectional study which included 111 male patients with chronic hepatitis C was conducted. …”
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Twin and triplet discordance in retinopathy of prematurity: a call to integrate genomic, placental, and environmental determinants by Zahra Sharifi, Mojtaba Heydari, Mohammadkarim Johari, Shayan Yousufzai

“…A post-hoc power analysis revealed limited statistical power for detecting subtle effects or rare events, indicating the necessity for larger studies. …”
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Expression of a Novel HIV-1 Gag-Pol-Env-Nef-Rev Multi-Epitope Construct in Escherichia coli by Elahe Akbari, Soheila Ajdari, Esmat Mirabzadeh Ardakani, Elnaz Agi, Vahid Khalaj, Azam Bolhassani

“…This study aimed to express an HIV-1 multiepitope protein as an antigen candidate to develop a vaccine.  Methods: In this study, the codon-optimized encoding sequence of the designed multi-epitope construct (Gag-Pol-Env-Nef-Rev) was synthesized and subcloned into the pET-24a (+) expression vector. …”
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Preliminary analysis of early and late radiation responses in 3D image-guided brachytherapy for cervical cancer by Olga B. Andreyeva, Tasbolat A. Adylkhanov, Dilyara R. Kaidarova, Isa G. Isayev, Tolegen S. Kurmangaliyev, Zaituna A. Khismetova, Natalya E. Glushkova

“…Conclusion – Hence, the method we have used to optimize the treatment of LACC by means of 3D planning in accordance with toxicity criteria exhibited a definite advantage, compared with RT with 2D planning. …”
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Consequences of Volcanic Ash on Antioxidants, Nutrient Composition, Heavy Metal Accumulation, and Secondary Metabolites in Key Crops of Cotopaxi Province, Ecuador by Raluca A. Mihai, Katherine Elizabeth Rodríguez Valencia, Nina G. Sivizaca Flores, Vivanco Gonzaga Ramiro Fernando, Cubi Isuaste Nelson Santiago, Rodica D. Catana

“…Secondary metabolites, particularly total phenols and flavonoids, were quantified using spectrophotometric methods, while heavy metal content was assessed via atomic absorption spectroscopy. …”
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A Field-Programmable Gate Array-Based Adaptive Sleep Posture Analysis Accelerator for Real-Time Monitoring by Mangali Sravanthi, Sravan Kumar Gunturi, Mangali Chinna Chinnaiah, Siew-Kei Lam, G. Divya Vani, Mudasar Basha, Narambhatla Janardhan, Dodde Hari Krishna, Sanjay Dubey

“…Monitoring sleep posture in real time is challenging, and this approach introduces hardware-based edge computation methods. Initially, we detected the postures using minimally optimized sensing modules and fusion techniques. …”
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Study on the effect of GCY-12 gene on albendazole sensitivity of Haemonchus contortus by RNA interference by Xindi Chen, Yaqin Shi, Tengyu Wang, Chunxia Liu, Wenlong Wang, Yu Wang

“…The reaction temperature was optimized, the expression of silenced eggs was detected by quantitative real-time polymerase chain reaction (qRT-PCR) technology, and the drug resistance of silenced eggs was detected by egg hatch assay (EHA).ResultsThe results showed that the gene expression level decreased significantly after GCY-12 interference, and the sensitivity of H. contortus to albendazole increased.DiscussionThis study highlights the potential role of GCY-12 in modulating albendazole resistance in H. contortus, offering new insights for developing effective therapeutic approaches.…”
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Identifying cognitive test scores associated with early tau burden in Alzheimer's disease by Caitlin M. Terao, Madeline Wood Alexander, R. Philip Chalmers, Silina Z. Boshmaf, Jane Paterson, Sandra E. Black, Kathryn V. Papp, Reisa A. Sperling, Jennifer S. Rabin

“…METHODS We analyzed cross‐sectional data from the harvard aging brain study (HABS) (n = 128) and the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's (A4) study (n = 393). …”
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Rapid Recovery and Short‐Term Culture of Gastric Circulating Tumor Cells Using Microcavity Array by Tomoko Yoshino, Tomohiro Takabayashi, Qian Bao, Tsuyoshi Tanaka, Ryo Negishi, Tatsu Shimoyama, Takeshi Sawada, Yusuke Kanemasa, Fumiaki Koizumi

“…These findings emphasize the importance of surface modification for enhancing CTC isolation and the need for optimized culture conditions. The optimized MCA method offers a promising approach for rapid CTC recovery and potential integration with automated systems. …”
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Additive manufacturing of a 3D-segmented plastic scintillator detector for tracking and calorimetry of elementary particles by Tim Weber, Andrey Boyarintsev, Umut Kose, Botao Li, Davide Sgalaberna, Tetiana Sibilieva, Johannes Wüthrich, Siddartha Berns, Eric Boillat, Albert De Roeck, Till Dieminger, Matthew Franks, Boris Grynyov, Sylvain Hugon, Carsten Jaeschke, André Rubbia

“…Abstract Plastic scintillators, segmented into small, optically isolated voxels, are used for detecting elementary particles and provide reliable particle identification with nanosecond time resolution. …”
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Use of a Silicon Microneedle Chip-Based Device for the Extraction and Subsequent Analysis of Dermal Interstitial Fluid in Heart Failure Patients by Markus Renlund, Laurenz Kopp Fernandes, Pelle Rangsten, Mikael Hillmering, Sara Mosel, Ziad Issa, Volkmar Falk, Alexander Meyer, Felix Schoenrath

“…Hollow microneedles represent one of the most promising platforms for access to pure dISF, enabling the mining of biomarker information. <b>Methods and Results:</b> Here, a microneedle-based method for dISF sampling is presented, where a combination of hollow microneedles and sub-pressure is used to optimize both penetration depth in skin and dermal interstitial fluid sampling volumes, and the design of an open, prospective, exploratory, and interventional study to examine the detectability of inflammatory and cardiocirculatory biomarkers in the dISF of heart failure patients, the relationship between dISF-derived and blood-derived biomarker levels, and their kinetics during a cardiopulmonary exercise test (CPET) is introduced. …”
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Review of the lumbar infusion test use in pediatric populations: state-of-the-art and future perspectives by Vojtěch Novák, Adéla Bubeníková, Petr Skalický, Arnošt Mládek, Václav Gerla, Afroditi Despina Lalou, Aleš Vlasák, Róbert Leško, Ondřej Bradáč

“…The LIT is a validated tool, especially effective for predicting shunt responsiveness and detecting malfunctions in both IIH and hydrocephalus. …”
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Automatic Diagnosis of Traumatic Brain Injury Using Deep Learning with CT scan Images by Behrang Rezvani Kakhki, Hossein Zakeri, Sayyed Majid Sadrzadeh, Seyed Mohammad Mousavi, elnaz vafadar moradi, golnoush shahraki

“…However, manual analysis of CT images is time-consuming and highly dependent on radiologists’ expertise.Material and Methods: This study proposes an automated approach for detecting intracranial hemorrhage and skull fractures using Convolutional Neural Networks (CNNs). …”
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Percolation and connectivity formation in the dynamics of data citation networks in high energy physics by Sergey O. Kramarov, Oleg R. Popov, Ismail E. Dzhariev, Egor A. Petrov

“…Improving the accuracy of information cycles in knowledge networks can help resolve applied problems related to the quality of scientometrics and its indicators.Methods. An optimized algorithm for dynamic network separation in the Pajek software environment was applied, in order to detect the emergence of a largest component equivalent to a percolation transition. …”
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Hydrogen-Rich Water Consumption for Acute and Residual Fatigue After Simulated Football Matches: Protocol for a Randomized, Double-Blinded, Placebo-Controlled, Parallel Trial by Michal Hruby, Karel Hulka, David Bernatik

“…These assessments will occur at critical time points: immediately post warm-up; directly following the simulated football match to detect acute fatigue; and 24, 48, and 72 hours after training sessions to detect residual fatigue. …”
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C - reactive protein predicts proximal femur osteomyelitis in suppurative hip arthritis by Haiting Jia, Tao Liu, Jiazhi Yu, Mingzhu Lu

“…The purpose of this study was to find out certain indicators to identify suppurative hip arthritis with proximal femur osteomyelitis in order to optimize MRI. Methods Data of 48 children with acute suppurative arthritis of the hip diagnosed and treated from March 2018 to September 2024 were retrospectively analyzed. …”
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Electronic structure of (Mn_{1−x}Pb_{x})Bi_{2}Te_{4}: Experimental evidence of topological phase transition by D. A. Estyunin, T. P. Estyunina, I. I. Klimovskikh, K. A. Bokai, V. A. Golyashov, K. A. Kokh, O. E. Tereshchenko, S. Ideta, Y. Miyai, Y. Kumar, T. Iwata, T. Kosa, T. Okuda, K. Miyamoto, K. Kuroda, K. Shimada, A. M. Shikin

“…The investigation of methods to control and optimize the physical properties of the intrinsic magnetic topological insulator (TI) MnBi_{2}Te_{4} is a critical challenge for the development of functional materials for quantum technologies and spintronics. …”
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Parameters of lipid and oxidative-antioxidant status in persons aged 18-23 from radiation-contaminated areas under conditions of moderate physical activity by Vadym L. Sokolenko, Svitlana V. Sokolenko

“…Some publications testify to the adaptive processes and the benefits of optimized exercise for various physiological systems, some deny such an effect. …”
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Diabetes: Non-Invasive Blood Glucose Monitoring Using Federated Learning with Biosensor Signals by Narmatha Chellamani, Saleh Ali Albelwi, Manimurugan Shanmuganathan, Palanisamy Amirthalingam, Anand Paul

“…Photoplethysmography (PPG), a photosensitive method that detects blood volume variations, has shown promise for non-invasive glucose monitoring. …”
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A Comparative Analysis of Mobile versus Stationary Mammography Units: Performance and Outcomes in a Breast Cancer Screening Program by Tari DU, De Lucia DR, Santonastaso R, Santarsiere M, Blasotti A

“…This study aimed to compare the outcomes of mammography screenings conducted in fixed units and MMUs, focusing on recall rates, follow-up adherence, and screen-detected breast cancer (BC) rates.Patients and Methods: This retrospective study analyzed data from 790 women aged 50– 69 years who underwent mammography screening between January and February 2023. …”
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