Prevalence and clinical significance of potential drug-drug interactions of antimicrobials in Intensive Care Unit patients: a retrospective study by Shanshan Xu, Zhihui Song, Jie Bai, Jiawei Wang

“…Discrepancies in DDI databases emphasize the need for multi-tool validation to optimize medication safety.…”
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Single-Visit Endodontic Therapy and Root Canal Identification Practices among Croatian Dentists: Insights from a National Survey by Josipa Sović, Sanja Šegović, Ivona Bago, Jurica Matijević, Ivan Tomašić

“…These findings underscore the role of education and resources in optimizing endodontic outcomes.…”
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Development and validation of a risk prediction model for acute kidney injury in coronary artery disease by Ming Ye, Chang Liu, Duo Yang, Hai Gao

“…This study focuses on developing accurate predictive models to improve the early detection and prognosis of AKI in CAD patients. Methods We used Electronic Health Records (EHRs) from a nationwide CAD registry including 54 429 patients. …”
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NUTRITIONAL SUPPORT ASPECTS WITH FAST TRACK PROGRAMME IN PLANNED SURGERIES FOR COLON CANCER IN ELDERLY PATIENTS by G. N. Khrykov, E. Yu. Strukov, A. D. Khalikov

“…Goal: to develop and evaluate the efficiency of the tactics for peri-operative nutritional-metabolic therapy as a component of Fast Track programme (FTP) in elderly patients suffering from colon cancer and having planned surgery. Methods. Treatment outcomes were analyzed for 400 elderly patients with colon cancer divided into two groups: main group (prospective n = 170), who were treated complying with optimized FTP and nutritional-metabolic therapy and control group (retrospective, n = 230), who were managed in the traditional way. …”
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Diastolic dysfunction types in the prediction of viable myocardium functional recovery by Matunović Radomir, Mijailović Zdravko, Tavčiovski Dragan, Ćosić Zoran, Stajić Zoran

“…In the preoperative period the medication therapy was optimized. We estimated CR by echocardiografic paremeters but also by detection of cardiovascular events. …”
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Manganese‐enhanced MRI during remotely induced myocardial ischemia reperfusion injury in male mice by Matic Pusovnik, Michiel Algoet, Willy Gsell, Stefan Janssens, Wouter Oosterlinck, Uwe Himmelreich

“…Abstract Early assessment of myocardial viability post‐ischemia is crucial to mitigate adverse remodeling and optimize therapy. Current noninvasive methods like late gadolinium enhancement (LGE) MRI may overestimate infarct size. …”
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Digital Health Approaches to Measles Surveillance in the Oltenia Region (January 2023 – June 2024) by Ana Maria BOLDEA, Alexandra ROTARU ZAVALEANU, Mircea SERBANESCU

“…Results: The implementation of digital surveillance and case monitoring systems allowed for the early detection of measles outbreaks and facilitated timely public health responses. …”
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Developing incisional hernia after open liver resection and liver transplantation: A single-center risk factor analysis by Saeed Aldarwish, Paula Guda, Mark Philipp, Clemens Schafmayer, Sebastian Hinz

“…But the leading risk factors can be modified or optimized. From our experience and according to this analysis, we recommend the careful selection of the surgical approach for each patient and promotion of the use of the minimally invasive approaches, avoiding the angulated incisions as much as possible, applying the running suture technique with (polydioxanone) PDS-loops for the fascial reconstruction, minimizing the intraoperative blood loss and need for blood transfusion, shortening the operative time as much as possible, early detection of postoperative formation of ascites, and managing it properly. …”
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Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study. by Myriam Calle Rubio, Joan B Soriano, José Luis López-Campos, Juan J Soler-Cataluña, Bernardino Alcázar Navarrete, José Miguel Rodríguez González-Moro, Marc Miravitlles, Miriam Barrecheguren, Manuel E Fuentes Ferrer, Juan Luis Rodriguez Hermosa, EPOCONSUL Study

“…However, when tested, AATD (based on the serum AAT levels ≤100 mg/dL) is detected in one in five COPD patients. Efforts to optimize AATD case detection in COPD are needed.…”
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Primary Prostatic Stromal Sarcoma: A Case Report and Review of the Literature by Enes Erul, Ömer Gülpınar, Diğdem Kuru Öz, Havva Berber, Saba Kiremitci, Yüksel Ürün

“…This case highlights the importance of early detection, complete surgical excision, and consideration of adjuvant therapies, given the aggressive nature of the disease. …”
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Deep learning model applied to real-time delineation of colorectal polyps by Moana Gelu-Simeon, Adel Mamou, Georgette Saint-Georges, Marceline Alexis, Marie Sautereau, Yassine Mamou, Jimmy Simeon

“…Although YOLACT has demonstrated real-time detection and segmentation in non-medical datasets, its application in medical settings remains underexplored. …”
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A Blockchain-Based Architecture of Web3.0: A Comprehensive Decentralized Model With Relay Nodes, Unique IDs and P2P by Hyunjoo Yang, Sejin Park

“…When faced with malicious requests, the system significantly reduces verification latency to an average of 0.0106 ms, ensuring rapid rejection and preserving network stability, while legitimate requests are processed efficiently with an average latency of 0.4125 ms.Experiments comparing latency-based and random-based relay selection methods across various network configurations (public-public, public-private, private-private) demonstrate that latency-based selection optimizes connection setup times in low-latency environments, while random-based selection provides robust performance in complex network scenarios. …”
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Analysis of the effect of maxillary transverse deficiencies on permanent maxillary first molar rotations using 3D digital models by Samet Özden, Orhan Cicek

“…Conclusion It was concluded that (i) mesiopalatal PMMRs are observed in the MTSDs with molar crossbite, (ii) molars with normal molar occlusal relationships have normal PMMR angles even in the presence of MTSDs, and (iii) early detection of MTSD enables timely interventions, preventing treatment delays and improving occlusal outcomes, particularly in developing patients, thereby optimizing long-term orthodontic results. …”
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Wearable Technologies for Health Promotion and Disease Prevention in Older Adults: Systematic Scoping Review and Evidence Map by Yue Sun, Ji Chen, Mengmeng Ji, Xiaomei Li

“…The most commonly reported health targets of wearable devices were mobility, mental health, fall-related, arrhythmia detection, activity recognition, disease diagnosis, and sleep monitoring. …”
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Using the model of closed-loop economy in certain branches of the agro-industrial complex by I. V. Petrunina, N. A. Gorbunova

“…The paper summarizes the main specific features typical of circular economy: strengthened control of supply of limited natural resources and maintenance of the stable balance of renewable resources; optimization of consumption processes by development and use of products, components and materials that correspond to the highest level of their reuse; detection and prevention of negative external effects of current production activities to increase efficiency of the economic and ecological systems. …”
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Exploring secular trends and types of tuberculosis burden in India over past three decades through insights from the Global Burden of Disease Study 2019 by Krittika Bhattacharyya, Ravi Prakash Jha, Deepak Dhamnetiya, Priyanka Patel, Neha Shri, Mayank Singh

“…Strengthening early detection, optimizing treatment strategies, and raising community awareness will be essential to curb the spread and impact of resistant TB forms, while mitigating the broader implications of AMR.…”
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Hypromellose improves mydriasis dynamics by phenylephrine in a rabbit experimental model by E. V. Blinova, G. K. Poluosmak, E. A. Litvin, D. S. Blinov, M. V. Shiсh, O. S. Vavilova, O. V. Vasilkina, E. V. Shich

“…Purpose: to determine the main characteristics of the mydriatic effect of drug formulations of phenylephrine, containing and not containing hypromellose, hyaluronic acid as an auxiliary component, in a comparative in vivo study, as well as to study their local bioavailability and the effect on the mucous membrane of the eye. Materials and methods. The studies were carried out on 40 adult male Soviet Chinchilla rabbits. …”
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The role and place of transanal endoscopic resections in rectal cancer by R. P. Nikitenko, V. M. Zaporozhan, K. O. Vorotyntseva, Ye. A. Koichev

“…Materials and methods. 184 operated patients with rectal cancer (RC) were divided into 2 groups: group 1 – patients with stage I RC (T1–2N0M0), and group 2 – stage II RC (T3N0M0), who underwent intraoperative detection and examination of sentinel lymph nodes. …”
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CXCR4+ Sorted Adipose-Derived Stem Cells Enhance Their Functional Benefits and Improve Cardiac Function after Myocardial Infarction by Zihui Yuan, Chuanqi Cai, You Qin, Kai Yan, Jian Wang

“…Fewer apoptotic cells under oxygen-glucose deprivation were detected in CXCR4+ sorted ASCs than in unfractionated ASCs. …”
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Investigating Flavonoids by HPTLC Analysis Using Aluminium Chloride as Derivatization Reagent by Sharmin Sultana, Md Lokman Hossain, Tom Sostaric, Lee Yong Lim, Kevin J. Foster, Cornelia Locher

“…A few non-flavonoid components with structural similarities to flavonoids (e.g., rosmarinic acid, gallic acid, aspirin, salicylic acid) served as the negative control in this study to determine whether the derivatization reagents allowed exclusive detection of flavonoids. The method was then applied to the analysis of flavonoid containing supplements as well as red clover honey to demonstrate the method’s application in the analysis of natural products.…”
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