The INTIMA: development and validation of a new psychometric tool for the evaluation of perceived ‘Viagra Jealousy’ in erectile dysfunction therapy by Daniele Mollaioli, Andrea Sansone, Tommaso B. Jannini, Bac Hoai Nguyen, Thang Cao Nguyen, Quan Minh Pham, Giacomo Ciocca, Emmanuele A. Jannini

“…ROC analysis revealed high discriminatory power for detecting insecure attachment patterns, with an optimal cut-off score of 17.Conclusion INTIMA is a reliable psychometric tool for assessing perceived VJ and predicting the risks of involving or not the partner in ED treatment and to identify optimal strategies for better adherence and outcomes.…”
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MALDI-TOF mass spectrometry combined with machine learning algorithms to identify protein profiles related to malaria infection in human sera from Côte d’Ivoire by Fateneba Kone, Lucie Conrad, Jean T. Coulibaly, Kigbafori D. Silué, Sören L. Becker, Brama Kone, Issa Sy

“…Additional research is warranted for further optimization such as specific biomarkers detection or using other ML models. …”
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Barriers and Facilitators to the Preadoption of a Computer-Aided Diagnosis Tool for Cervical Cancer: Qualitative Study on Health Care Providers’ Perspectives in Western Cameroon by Magali Jonnalagedda-Cattin, Alida Manoëla Moukam Datchoua, Virginie Flore Yakam, Bruno Kenfack, Patrick Petignat, Jean-Philippe Thiran, Klaus Schönenberger, Nicole C Schmidt

“…ObjectiveThis study investigated the barriers and facilitators perceived by HCPs in Western Cameroon regarding sustained CAD tool use for cervical cancer detection using VIA. The aim was to guide smooth technology adoption in similar settings by identifying specific barriers and facilitators and optimizing CAD’s potential benefits while minimizing obstacles. …”
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SENSING OF PROSTATE SPESIFIC ANTIGEN BY DIFFERENTIAL PULSE ANODIC STRIPPING VOLTAMMETRY OF GOLD NANOPARTICLE - SILVER ENHANCED LABELS by Rika Endara Safitri, Ani Mulyasuryani, Attasith Parnsubsakul, Patsamon Rijiravanich

“…The measurement conditions and immunoassay components had been optimized in this study. The detection of PSA was successfully carried out by this method with limit detection value of 152.204 ng/mL, but further development is necessary to improve the limit detection value.…”
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Determination of estradiol and progesterone concentrations in human scalp hair by E. Kadour-Peero, S. Khoury, J. Awad, L. Shpritz, L. Chen-Konak, C. Shechner, L. Saiegh

“…Conclusion: Hair E and P concentrations can be quantified by immunoassay but it may not be the optimal method. Future studies should be conducted in order to determine the optimal technique in measurement of these hormones from scalp hair.…”
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Validation of the patient health questionnaire (PHQ)-9 and PHQ-2 in patients with COPD in China by Meishan Liu, Yuhan Chang, Dong Wang, Jiexin Fang, Shannon Carson, Boyu Li, Yongdong Hu, Kewu Huang

“…Conclusion PHQ-9 score ≥ 7 and PHQ-2 score ≥ 2 should be used as the optimal cut-offs for COPD patients in China. PHQ-9 is a valid tool for detecting MDD in COPD patients, while PHQ-2 (score < 2) is more useful for quickly excluding MDD.…”
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Simultaneous Electrochemical Determination of Uric Acid, Xanthine, and Hypoxanthine Using AgNPs/MIL-101(Cr) Modified Electrode by Nguyen Quang Man, Nguyen Ngoc Nghia, Vo Thi Khanh Ly, Nguyen Duc Vu Quyen, Le Thi Hoa, Ho Van Minh Hai, Le Van Thanh Son, Le Thi Hong Phong, Nguyen Dinh Luyen, Nguyen Chi Bao, Dinh Quang Khieu

“…This method was used to analyze URA, XAT, and HPX in human urine; the results were not statistically different from the standard HPLC method. …”
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SINS/OD integrated navigation system for shearer based on robust closed-loop path calibration by YAN Ming, FU Xiang, WANG Ranfeng, YANG Xinyu, LIU Bin

“…First, velocity and position measurement error equations were established based on the shearer's motion constraint model, and a Kalman filter (KF) model was constructed to achieve optimal position estimation. Then, the MCCKF was adopted to replace the traditional KF, reducing the interference caused by erroneous predicted positions in the traditional closed-loop calibration method on straightness detection. …”
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Evaluation of Study and Patient Characteristics of Clinical Studies in Primary Progressive Multiple Sclerosis: A Systematic Review. by T Ziemssen, S Rauer, C Stadelmann, T Henze, J Koehler, I-K Penner, M Lang, D Poehlau, M Baier-Ebert, H Schieb, S Meuth

“…In addition, the endpoints specified could not detect progression adequately.<h4>Conclusion</h4>Optimal PPMS study methods involve appropriate patient selection, especially regarding the PPMS phenotype and progression rate. …”
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Hybridisation of artificial neural network with particle swarm optimisation for water level prediction by Sarah J. Mohammed, Salah L. Zubaidi

“…This study applies an artificial neural network (ANN) integrated with the particle swarm optimisation algorithm (PSO-ANN) for simulating monthly WL of the Tigris River in Alkut City, Iraq. Data pre-treatment methods are utilised for improving raw data quality and detect the optimal predictors. …”
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Stroke occurring in patients with cognitive impairment or dementia by Solène Moulin, Didier Leys

“…These patients have less access to appropriate stroke care, although little is known about their optimal management. Objective To determine how pre-stroke cognitive impairment can be detected, its mechanism, and influence on outcome and management. …”
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Predictive Model for Diagnosis of Gestational Diabetes in the Kurdistan Region by a Combination of Clustering and Classification Algorithms: An Ensemble Approach by Rasool Jader, Sadegh Aminifar

“…The suggested model uses the clustering KMeans technique for data reduction and the elbow method to find the optimal k value and the Mahalanobis distance method to find more related cluster to new samples, and the classification methods such as decision tree, random forest, SVM, KNN, logistic regression, and Naïve Bayes are used for prediction. …”
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Inguinal sebaceous gland carcinoma : A rare case report and literature review by Khanh Ha Nguyen, Thi Thanh Trinh

“…In conclusion, inguinal sebaceous gland carcinoma is sporadic, so clinical features and optimal treatment methods are poorly understood. Further research is warranted to clarify this rare condition.…”
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Correlation of Vitamin D with left ventricular hypertrophy in maintenance hemodialysis patients by ZOU Yuan-fang, DENG Hui-zhao, LIANG Xiang, LUO Wan-ying

“…Objective To study the relationship between left ventricular hypertrophy（LVH）and Vitamin D [25（OH）D₃] in maintenance dialysis patients.Methods The clinical and laboratory results of 80 patients with maintenance dialysis were retrospectively analyzed.Meanwhile,Vitamin D levels were detected with radioimmunoassay.The relationships between serum Vitamin D levels and some laboratory parameters were analyzed by using Pearson correlation analysis.The risk factors of left ventricular hypertrophy were investigated through Logistic regression analysis.ROC curve was used to analyze 25（OH）D₃ and predict the optimal cutoff value of LVH.Results Serum 25（OH）D₃ levels of 80 patients with maintenance hemodialysis were（15.2±3.6）ng/mL.The 25（OH）D₃ levels of the patients in the LVH group were significantly lower than those in the non-LVH group[（13.5±2.8）vs（17.8±3.2）ng/mL,P<0.05].The 25（OH）D₃ levels exhibited negative correlation with left ventricular end diastolic diameter（LVDd）,left ventricular posterior wall thickness（LVPWT）,interventricular septum thickness（IVST）and left ventricular mass index（LVMI）,and positive correlation with left ventricular ejection fraction（LVEF）（r=-0.582,P=0.032;r=-0.562,P=0.038;r=-0.498,P=0.046;r=-0.641,P=0.024;r=0.726,P=0.018）.Multivariable logistic regression analysis showed that low 25（OH）D₃,C-reaction protein（CRP）,total cholesterol（TC）,hypertension,anemia were independent risk factors for LVH;ROC curve analysis showed the area under the curve that baseline serum Vitamin D deficiency was used to predict an area under the curve of 0.842,with the optimal cutoff value of 14.28 ng/mL,sensitivity of 68.8% and specificity of 81.2%.Conclusions The 25（OH）D₃ levels of patients with maintenance hemodialysis decrease significantly,and vitamin D deficiency is an independent factor of LVH in MHD patients.Vitamin D deficiency may be involved in pathogenesis and progression of cardiovascular diseases in hemodialysis patients.…”
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RAPID: Redundancy Analysis With Parallelized and Intelligent Distribution by Younwoo Yoo, Hayoung Lee, Seung Ho Shin, Sungho Kang

“…The main goal of RA is to optimally place spare cells rapidly to achieve the highest repair rate, resulting in the development of various RA methods. …”
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Simultaneous Determination of α,β-Unsaturated Aldehydes in Emulsion Using Supercritical Fluid Chromatography-Tandem Mass Spectrometry by WANG shu, WEI Shixiao, ZHANG hao, SUN Shangde, BI Yanlan

“…In order to effectively improve the detection of α,β-unsaturated aldehydes in emulsion, this study established an efficient and sensitive detection method using supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS). …”
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Hereditary Colorectal Cancer Syndromes: Small Bowel Cancer Risk and Endoscopic Surveillance Strategies by Edoardo Borsotti, Francesca Laura Nava, Felice Benedicenti, Laura Cini, Andrea Magarotto, Davide Ferrari, Paolo Cantù, Marco Vitellaro, Emanuele Rausa, Federica Cavalcoli

“…In PJS, surveillance aims to mitigate intussusception risks and allow early malignancy detection. <b>Conclusions:</b> Optimized surveillance strategies in hereditary colorectal cancer syndromes require a multimodal approach, integrating advanced endoscopic techniques with genetic risk stratification. …”
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Correlating gene expression levels with transcription factor binding sites facilitates identification of key transcription factors from transcriptome data by Tinghua Huang, Siqi Niu, Fanghong Zhang, Binyu Wang, Jianwu Wang, Guoping Liu, Min Yao

“…ED was identified as the optimal method for creating a ranked gene list from filtered expression data, which can address the “unable to detect negative correlation” fallacy presented by other methods. …”
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Differential diagnosis of ovarian neoplasm using contrast-enhanced ultrasound (clinical case) by N. Е. Safonova, N. М. Podzolkova, V. В. Osadchev, K. V. Babkov, I. Е. Fadeev

“…That’s why an important task is to create optimal algorithms for diagnosing and routing patients in case of suspicion of an adnexal tumor. …”
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High-Accuracy Iris Center Localization Using Mediapipe Keypoints and Xception-Based Deep Regression by Wattanapong Kurdthongmee, Arsanchai Sukkuea, Korakot Suwannarat, Piyadhida Kurdthongmee

“…These findings highlight the method&#x2019;s enhanced efficacy relative to current methodologies, offering an effective and reliable alternative for real-time iris localization and analysis.…”
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