Differential patterns of the relationship between exercise dose and mortality risk across severities of airflow limitation: a prospective cohort study with a 5-year follow-up perio... by Yide Wang, Hongxia Duan, Yingqi Wang, Yidie Bao, Linhong Jiang, Xiaoyu Han, Fengsen Li, Peijun Li, Weibing Wu, Xiaodan Liu

“…Subjects/Patients: A total of 2,975 individuals from a cohort categorized by airflow limitation severity (normal, GOLD 1–4). Methods: PA levels were quantified in metabolic equivalent hours per week (MET·h/week). …”
Get full text

Effect of enamel pretreatment on the fluoride remineralization of artificial white spot lesions by Diana Ferreira Gadelha Araújo, Fernanda Sandes de Lucena, Maria Cristina Carvalho de Almendra Freitas, Larissa Vasconcellos Nunes, Marília Mattar de Amoedo Campos Velo, Ana Carolina Magalhães, Linda Wang

“…Material and Methods: Twenty-four enamel bovine blocks were obtained and selected by means of initial surface microhardness (SMH) measurements. …”
Get full text

Multicenter study on long-term growth in patients with phenylketonuria by S. Stanescu, A. Belanger-Quintana, J. C. Rocha, M. F. Almeida, K. Ahring, K. Dokoupil, A. M. Lammardo, E. van Dam, A. Muriel, A. MacDonald, on behalf of the ENEP group

“…The aim of this study is to determine whether the patients with PKU have a normal growth, the incidence of obesity and the relationship of these parameters with diet and nutritional intake. Material and methods This is a retrospective, multicenter, multinational study including patients with PKU from 8 centers from different countries. …”
Get full text

Balancing accuracy and user satisfaction: the role of prompt engineering in AI-driven healthcare solutions by Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Peijin Zeng, Peijin Zeng, Peijin Zeng, Xinyue Li, Kelvin Kam-Lung Chong, Guanghui Hou, Xiaoxiao Fang, Yang Yu, Xiangrong Yu, Junbin Fang, Yi Pan

“…This study explores the application of IoT-enabled, AI-driven systems for detecting and managing Dry Eye Disease (DED), emphasizing the use of prompt engineering to enhance system performance.MethodsA specialized prompt mechanism was developed utilizing OpenAI GPT-4.0 and ERNIE Bot-4.0 APIs to assess the urgency of medical attention based on 5,747 simulated patient complaints. …”
Get full text

Impact of respiratory syncytial virus on Streptococcus pneumoniae resistance to β-lactam antibiotics: an investigative study in children by Lu Li, Yushun Wan, Yuncheng Wang, Ye Tao, Xiao Long, Enmei Liu, Yu Deng

“…Abstract Background This study characterizes the molecular interplay between respiratory syncytial virus (RSV) glycoproteins (G/F) and Streptococcus pneumoniae (S.pn) penicillin-binding proteins (PBPs), while evaluating RSV’s potential role in modulating S.pn β-lactam resistance. Methods Protein docking and pull-down assays assessed G/F-PBP interactions. …”
Get full text

Study Protocol of Expanded Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro-EXP) by Jae Hoon Moon, Eun Kyung Lee, Wonjae Cha, Young Jun Chai, Sun Wook Cho, June Young Choi, Sung Yong Choi, A Jung Chu, Eun-Jae Chung, Yul Hwangbo, Woo-Jin Jeong, Yuh-Seog Jung, Kyungsik Kim, Min Joo Kim, Su-jin Kim, Woochul Kim, Yoo Hyung Kim, Chang Yoon Lee, Ji Ye Lee, Kyu Eun Lee, Young Ki Lee, Hunjong Lim, Do Joon Park, Sue K. Park, Chang Hwan Ryu, Junsun Ryu, Jungirl Seok, Young Shin Song, Ka Hee Yi, Hyeong Won Yu, Eleanor White, Katerina Mastrocostas, Roderick J. Clifton-Bligh, Anthony Glover, Matti L. Gild, Ji-hoon Kim, Young Joo Park

“…The second phase of MAeSTro (MAeSTro-EXP) expands AS to low-risk papillary thyroid carcinoma (PTC) tumors larger than 1 cm, driven by the hypothesis that overall risk assessment outweighs absolute tumor size in surgical decision-making. Methods This protocol aims to address whether limiting AS to tumors smaller than 1 cm may result in unnecessary surgeries for low-risk PTCs detected during their rapid initial growth phase. …”
Get full text

Does Syndesmotic Fixation Technique Impact Complication Rates and Functional Outcomes Measured by PROMIS Scores Following Operative Repair of Ankle Fractures? by Steven Hadley BA, Rachel Bergman MD, John Peabody MD, Sarah Westvold MPH, Ryan Filler MD, Milap Patel DO, Anish Kadakia MD

“…Analysis of PROMIS scores had 80% power to detect large effect sizes (Cohen’s f = 0.40) with a 0.05 significance level but was underpowered for small and medium effects. …”
Get full text

Influence of Fermentation of Eurotium cristation on the Flavor Characteristics of Guizhou White Tea by Jinlong LUO, Zhongying LIU, Shimao FANG, Tuo ZHANG, Yuqiao DAI, Xiaowei YANG, Ting YANG, Mengzhen ZHU, Qiang SHEN

“…A total of 74 aroma substances were detected in WT and ECWT, of which 62 were key differential aroma substances and 49 were detected in WT. …”
Get full text

Exploring the influence of sex and age on the quality and flavor of Huai goat longissimus thoracis et lumborum through transcriptomic and metabolomic analyses by Haoyuan Han, Ziru Kuai, Zhiyun Yao, Xi Lei, Huibin Shi, Jun Li, Kun Liu, Huiru Yin, Yongqing Wang, Kai Quan

“…Abstract Background The aim of this study was to investigate the effects of age and sex on the composition of fatty acids, amino acids, and vitamins in the longissimus thoracis et lumborum (LTL) of Huai goats. Methods The longissimus thoracis et lumborum tissues of eight Huai goats were collected postslaughter and analyzed for amino acids, fatty acids, and vitamins by gas chromatography‒mass spectrometry (GC‒MS) and standard methods. …”
Get full text

A Multimodal Pain Sentiment Analysis System Using Ensembled Deep Learning Approaches for IoT-Enabled Healthcare Framework by Anay Ghosh, Saiyed Umer, Bibhas Chandra Dhara, G. G. Md. Nawaz Ali

“…In the second phase, the system extracts discriminant and divergent features from the facial region using deep learning techniques, utilizing some convolutional neural network (CNN) architectures, which are further refined through transfer learning and fine-tuning of parameters, alongside fusion techniques aimed at optimizing the model’s performance. The third phase performs the speech-audio recording preprocessing; the extraction of significant features is then performed through conventional methods followed by using the deep learning model to generate divergent features to recognize audio-based pain sentiments in the fourth phase. …”
Get full text

Popliteal Artery Injury Following Knee Dislocation: Anatomy, Diagnosis, Treatment, and Outcomes by Kunj C. Vyas, Michael Abaskaron, Mikaila Carpenter, Taylor Manes, Morgan Turnow, Daniel T. DeGenova, Benjamin C. Taylor

“…<b>Conclusions</b>: Knee dislocations with popliteal artery injury require rapid diagnosis and early surgical intervention to optimize functional outcomes and reduce complications. …”
Get full text

Comparison of the effects and mechanisms of Alismatis Rhizoma with and without salt processing in ameliorating edema due to kidney Yin deficiency based on UPLC-Q-TOF-MS and transcr... by Lin Yan, Zemin Ou, Yi Cheng, Yan Tong, Javed Iqbal, Jinyu Wang, Dewen Liu

“…A total of 63 terpenoids were detected in AR and SAR, and salt processing had a significant effect on the content of terpenoids. …”
Get full text

Advancements and gaps in natural language processing and machine learning applications in healthcare: a comprehensive review of electronic medical records and medical imaging by Priyanka Khalate, Shilpa Gite, Shilpa Gite, Biswajeet Pradhan, Chang-Wook Lee

“…The focus is on the use of these technologies in Electronic Medical Records (EMRs) and medical imaging. The review methodically detects, chooses, and assesses literature published between 2015 and 2023, utilizing keywords pertaining to natural language processing (NLP) and healthcare in databases such as SCOPUS. …”
Get full text

Wind Turbine Static Errors Related to Yaw, Pitch or Anemometer Apparatus: Guidelines for the Diagnosis and Related Performance Assessment by Davide Astolfi, Silvia Iuliano, Antony Vasile, Marco Pasetti, Salvatore Dello Iacono, Alfredo Vaccaro

“…The optimization of the efficiency of wind turbine systems is a fundamental task, from the perspective of a growing share of electricity produced from wind. …”
Get full text

Characteristics and outcomes of acute stroke in COVID-19 patients by Dr Chee Peng Hor, Dr. Hooi Xian Wang, Dr. Joo Thye Cheng, Dr. Norhasimawati Abdul Mutalib, Dr. Irene Looi

“…With an evolving understanding of stroke in COVID-19, we can further optimize stroke care.…”
Get full text

Predicting Quality of Life in People Living with HIV: A Machine Learning Model Integrating Multidimensional Determinants by Meilian Xie, Zhiyun Zhang, Yanping Yu, Li Zhang, Jieli Zhang, Dongxia Wu

“…We therefore aimed to develop and validate machine learning models that predict QoL trend in PLWH, identifying key determinants to inform personalized interventions and optimize long-term well-being. Methods In this longitudinal observational study, PLWH were recruited from March 2024 to December 2024. …”
Get full text

The use of artificial intelligence in the diagnosis of oral carcinoma by Francesco Gianfreda, Andrea Danieli, Maria Scarpati Cioffari di Castiglione, Marco Gargari, Patrizio Bollero, Mirko Martelli

“…Discussion: AI shows immense potential in optimizing oral carcinoma diagnosis and treatment processes, as evidenced by various studies. …”
Get full text

Nonproteinuric Preeclampsia among Women with Hypertensive Disorders of Pregnancy at a Referral Hospital in Southwestern Uganda by Asiphas Owaraganise, Richard Migisha, Wasswa G. M. Ssalongo, Leevan Tibaijuka, Musa Kayondo, Godfrey Twesigomwe, Joseph Ngonzi, Henry Mark Lugobe

“…We recommend increased surveillance for nonproteinuric preeclampsia, especially among first-time pregnant women, who may not be detected by the traditional criteria. Obstetrics care providers should emphasize laboratory testing beyond proteinuria, among all women with hypertensive disorders of pregnancy to optimally diagnose and manage nonproteinuric preeclampsia.…”
Get full text

Generation of Cas9 Knock-In <i>Culex quinquefasciatus</i> Mosquito Cells by Elizabeth Walsh, Tran Zen B. Torres, Brian C. Prince, Claudia Rückert

“…To expand the genetic tools used to study <i>Culex</i> mosquitoes, we previously developed an optimized plasmid for transient Cas9 and single-guide RNA (sgRNA) expression in <i>Culex quinquefasciatus</i> cells to generate gene knockouts. …”
Get full text

Perioperative Arthroscopic Tourniquet Usage: Practices and Trends of the AANA Membership Are Varied by Brian Day, M.B., M.Sc., F.R.C.P.(Lon), F.R.C.S.(Eng and C)

“…Purpose: To investigate current practices for tourniquet use, including tourniquet times, indications, and other perioperative applications, among Arthroscopy Association of North America (AANA) members and to determine whether recommendations can be made for safer tourniquet use. Methods: Participants in this study were AANA members who responded to our survey in the AANA DocMatter Community. …”
Get full text