Complement inhibitor therapy in thymoma-associated myasthenia gravis: a real-world experience by Sofia Marini, Carmen Erra, Laura Fionda, Silvia Falso, Elena Rossini, Elena Rossini, Federico Habetswallner, Elisa Meacci, Martina Marini, Francesco Habetswallner, Raffaele Iorio, Raffaele Iorio

“…However, TAMG patients are underrepresented in clinical trials, leaving gaps in evidence for optimal treatment strategies. This study assessed the efficacy of complement inhibitors (CI) in TAMG population.MethodsWe retrospectively reviewed 23 TAMG patients who received CI, with a minimum follow-up of six months. …”
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Relationship between extracellular matrix metalloproteinase inducer and myocardial ischemic reperfusion injury by WANG Na，CHEN Changzheng，SHI Yankun，YANG Zhihua，FAN Jun，YANG Lixia

“…The serum EMMPRIN level was detected by enzyme-linked immunosorbent assay. Multivariate binary logistic regression was used to analyze the independent risk factors related to MIRI. …”
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3T BOLD and DW magnetic resonance imaging quantitative parameters for prediction of early diabetic nephropathy by Omnia Ezz Eldin, Yahya Bashir Ali, Noha Mohamed Elkholy, Yasser Mazloum, Ashraf Naguib Ettaby

“…This study aimed to assess the role of blood oxygen level dependent (BOLD) and diffusion-weighted imaging (DWI) magnetic resonance imaging (MRI) techniques as predictive tools for the early stages of diabetic nephropathy. Methods This prospective ethically approved study was conducted from December 2022 to February 2024, enrolling 40 participants. …”
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Imaging modalities for characterising T1 renal tumours: A systematic review and meta‐analysis of diagnostic accuracy by Hannah Warren, Jack B. Fanshawe, Valerie Mok, Priyanka Iyer, Vinson Wai‐Shun Chan, Richard Hesketh, Eleanor Zimmermann, Veeru Kasivisvanathan, Mark Emberton, Maxine G. B. Tran, Kurinchi Gurusamy

“…Our objective was to determine diagnostic accuracy of imaging modalities for detecting cancer in T1 renal tumours. Methods A systematic review was performed for reports of diagnostic accuracy of any imaging test compared to a reference standard of histopathology for T1 renal masses, from inception until January 2023. …”
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Definition of metafounders based on population structure analysis by Christine Anglhuber, Christian Edel, Eduardo C. G. Pimentel, Reiner Emmerling, Kay-Uwe Götz, Georg Thaller

“…The objective of this study was to identify stratification using genomic data and to transfer this information to matrix $$\mathbf{A}$$ A , to improve the compatibility of $$\mathbf{A}$$ A and $$\mathbf{G}$$ G . Methods Using software to detect population stratification (ADMIXTURE), we developed an iterative approach. …”
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Approach to automating viral genome assembly by Ms Anastasiia Paremskaia, Dr Andrei Deviatkin, Dr Pavel Volchkov

“…However, the remaining portion of this segment shows no homology. In this case, the optimal solution would be to select the most suitable reference from a representative database. …”
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Revisiting cost-effectiveness of TB infection screening using IGRAs: focus on a comprehensive approach by Dr Vladyslav Nikolayevskyy, Mr Riccardo Alagna, Mr Marc Destito

“…Methods: High costs have long been considered among major obstacles for implementation of WHO-endorsed Interferon-Gamma Releasing Assays (IGRA) in endemic settings [Faust et al., 2020]. …”
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An elevated percentage of CD4⁺CD25⁺CD127low regulatory T cells in peripheral blood indicates a poorer prognosis in hepatocellular carcinoma after curative hepatectomy by Haoran Sun, Zepeng Cao, Baochen Zhao, Dachen Zhou, Zhongbiao Chen, Bin Zhang

“…X-tile software was used to calculate optimal cut-off value of Treg percentage (5.85%), and patients were divided into two groups with high and low Treg percentage. …”
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Wearable sensor use for assessing standing balance and walking stability in people with Parkinson's disease: a systematic review. by Ryan P Hubble, Geraldine A Naughton, Peter A Silburn, Michael H Cole

“…However, no consensus currently exists on the optimal placements for sensors and the best outcome measures to use for assessing standing balance and walking stability in Parkinson's disease patients. …”
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Poor glycemic control and its predictors among people living with diabetes in low- and middle-income countries: a systematic review and meta-analysis by Abere Woretaw Azagew, Chilot Kassa Mekonnen, Mark Lambie, Thomas Shepherd, Opeyemi O. Babatunde

“…The funnel plot asymmetry test and/or Egger’s regression test (p < 0.05) were used to detect the publication bias. Then it was treated by the trim and fill analysis. …”
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Modern clinical portrait of ovarian cancer patient in the Novosibirsk region by A. V. Tarkhov, M. A. Goncharov, A. V. Tereschenko, N. Yu. Zvezdina, N. A. Buksel, D. K. Ukolova, L. Yu. Konovalova, D. K. Nikitina, D. V. Morozov, M. S. Selyakova

“…Primary complete or optimal cytoreductive surgery was performed in 82.7 % of patients with all stages of ovarian cancer. …”
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Analysis of MMP-8, MMP-20, and TGF-β1 in molar-incisor hypomineralization and assessment of periodontal health by Başak Senian Bilgir, Sema Aydınoğlu, İpek Arslan, Mehtap Atak, Oğuz Köse, Dilara Nil Günaçar

“…Finally, the ROC curve was used to determine the optimal cut-off value for MMP-20. Results PI, GI, PPD, and GCF volume values were significantly higher in the SG than in CG (p < 0.001, p = 0.007, p = 0.001, p = 0.007, respectively). …”
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Comparative evaluation of immunomodulatory cytokines for oncolytic therapy based on a high-efficient platform for oHSV1 reconstruction by Yingzheng Gao, Yufang Zou, Changjing Wu, Juan Tao, Zuqing Nie, Jinyuan Yan, Pengfei Wang, Xinwei Huang

“…Methods We developed a CRISPR/Cas9-mediated platform for high-efficiency oHSV1 engineering, replacing the ICP47 locus with murine IFN-γ, GM-CSF, or IL-15Rα/IL-15 fusion protein (IL15Fu). …”
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Histological response and blood glucose level in a diabetic animal model after the oral administration of Mucuna pruriens: A systematic review and meta-analysis by Tri Wahyu Pangestiningsih, Dian Meididewi Nuraini, Morsid Andityas, Ariana Ariana

“…Potential publication bias was detected but was addressed through trim-and-fill analysis. …”
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Comparative Analysis of Irrigation Mist and CO₂ vs. Direct CO₂ Blower in On-Pump Coronary Artery Bypass Grafting Anastomosis: Efficacy, Efficiency, and Fibril... by Ignazio Condello, Giuseppe Speziale, Flavio Fiore, Giuseppe Nasso

“…<i>Background and Objectives:</i> In coronary artery bypass grafting (CABG) on pump, achieving optimal visualization is critical for surgical precision and safety. …”
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Association between male (in)fertility and telomeric dysfunction: a systematic review and meta-analysis by Sunny Kumar Jignesh Kumar Patel, Amit Roy Chowdhury, Sujata Kar, Purna Chandra Mohapatra, Birendranath Banerjee

“…Objective The aim of this meta-analysis was to evaluate the clinical significance and sperm cell reliability for TL assessment (sperm/leukocytes) as a novel predictive biomarker in male (in)fertility, with an overview of general trends. Methods A comprehensive systematic search was carried out for relevant research. …”
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Unprotected left main revascularization: Percutaneous coronary intervention versus coronary artery bypass. An updated systematic review and meta-analysis of randomised controlled t... by Luca Testa, Azeem Latib, Mario Bollati, Rocco Antonio Montone, Antonio Colombo, Filippo Crea, Francesco Bedogni

“…<h4>Background</h4>The optimal treatment of unprotected left main (UPLM) with either PCI or CABG remains uncertain.…”
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Effects of acute weight loss on serum mineral homeostasis in elite male judoka by Burcu Yenturk, Mihrac Koroglu, Nuri Muhammet Celik, Cuneyt Sensoy, Fıkret Soyer

“…No significant changes were detected in the other serum minerals within the experimental group or in any parameter among the control group. …”
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Reevaluating Backup Monitor Chamber Tolerances for Stereotactic Body Radiotherapy Treatments using Volumetric-modulated Arc Therapy by Yong Sang, Jun Dang, Jianan Wu, Enzhuo Quan

“…Conclusions: The current 2% constancy tolerance may not be optimal for SBRT treatments on the Elekta Infinity accelerator. …”
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Effectiveness of human albumin for clinical outcome in aneurysmal subarachnoid hemorrhages: a protocol for randomized controlled (HASH) trial by Arshad Ali, Mohsin Khan, Nissar Shaikh, Amr El Mohamad, Mazyona Al-Maadhadi, Noman Shah, Yousef Al-Najjar, Abdul Salam, Ghaya Al-Rumaihi, Ali Ayyad, Sirajeddin Belkhair, Ghanem Al-Sulaiti

“…Discussion The trial aims to provide firsthand evidence on the beneficial use of human albumin to achieve an optimal fluid management regime to explore its potential role in improving clinical outcomes in patients with aSAH. …”
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