Precision medicine in oncology: role and prospects of mass spectrometry by E. S. Khmelevskaya, E. A. Perina, E. E. Buyko, A. A. Ufandeev, O. A. Kaidash, V. V. Ivanov, A. N. Baikov, E. V. Parochkina, E. V. Udut

“…Over the next decade, introduction of mass spectrometry-based methods into clinical practice based on the principles of precision medicine is expected to optimize selection of personalized treatment strategies for cancer patients and provide significant economic benefits by reducing morbidity, disability, and mortality.This comprehensive review presents the analysis of 65 scientific publications, highlighting the results of clinical and experimental studies utilizing mass spectrometry methods for diagnosing cancer, investigating the underlying mechanisms of disease development, and evaluating the efficacy of therapeutic interventions. …”
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Glial Fibrillary Acidic Protein’s Usefulness as an Astrocyte Biomarker Using the Fully Automated LUMIPULSE^® System by Jo Kamada, Tomohiro Hamanaka, Aya Oshimo, Hideo Sato, Tomonori Nishii, Marika Fujita, Yoshiharu Makiguchi, Miki Tanaka, Katsumi Aoyagi, Hisashi Nojima

“…The assay’s parameters, including antibody concentrations, incubation times, and detection methods, were optimized to enhance sensitivity and specificity. …”
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Spatial distribution of mixed milk feeding and its determinants among mothers of infants aged under 6 months in Ethiopia: Spatial and geographical weighted regression analysis. by Mekuriaw Nibret Aweke, Muluken Chanie Agimas, Moges Tadesse Abebe, Tigabu Kidie Tesfie, Meron Asmamaw Alemayehu, Werkneh Melkie Tilahun, Gebrie Getu Alemu, Worku Necho Asferie

“…The aim of this study was to analyze the spatial distribution and predictors of MMF practices in Ethiopia.<h4>Methods</h4>This study utilized data from the 2019 Mini-Ethiopian Demographic and Health Survey (MiniEDHS), a nationally representative cross-sectional survey conducted from March to June 2019. …”
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[18F]FDG PET/CT performs better than CT in determining the bone biopsy site : randomized controlled clinical trial by Yujie Chang, Yifeng Gu, Shunyi Ruan, Shengyu Xu, Jing Sun, Zhiyuan Jiang, Guangyu Yao, Zhiyu Wang, Hui Zhao

“…Methods We compared the performance of [18F]FDG PET/CT with CT in detecting bone metastases to achieve the highest biopsy efficiency. …”
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Exploring Machine Learning Classification of Movement Phases in Hemiparetic Stroke Patients: A Controlled EEG-tDCS Study by Rishishankar E. Suresh, M S Zobaer, Matthew J. Triano, Brian F. Saway, Parneet Grewal, Nathan C. Rowland

“…Certain movement phases are more responsive to NIBS, so a system that auto-detects these phases would optimize stimulation timing. …”
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Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review by Natáli T. Capistrano Costa, Allana M. de Souza Pereira, Cibele C. Silva, Emanuelle de Oliveira Souza, Beatriz C. de Oliveira, Luiz Felipe G. R. Ferreira, Marcelo Z. Hernandes, Valéria R. A. Pereira

“…Nevertheless, the diagnostic methods do eventually have limitations, and there is no established gold standard. …”
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Development of a Simple and Accurate Molecular Protocol Using 16SrRNA for Species-Specific Identification of <i>Achromobacter</i> spp. by Giulia Maria Saitta, Laura Veschetti, Rebecca Feletti, Angela Sandri, Marzia Boaretti, Paola Melotti, Maria Carelli, Maria M. Lleò, Giovanni Malerba, Caterina Signoretto

“…Thermal profiles were optimized, and qPCR was performed on serial bacterial DNA dilutions to determine the detection limit (LOD). …”
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Optimasi Fuzzy C-Means dan K-Means Menggunakan Algoritma Genetika untuk Pengklasteran Dataset Diabetic Retinopathy by Muhammad Ezar Al Rivan, Steven Steven, William Tanzil

“…Retina disorder can be known from data extracted from eye image. Early detection conduct using clustering. These methods are Fuzzy C-Means and K-Means. …”
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PSYCHOLOGICAL AND PEDAGOGICAL BASES OF FORMATION OF THE FUTURE SPECIALISTS’ INDIVIDUAL STYLE OF PROFESSIONAL ACTIVITIES by Lavrentieva Olena, Krupskyi Oleksandr

“…It has been established that the individual style of professional activity is a complex personal creation including a stable system of work methods and techniques, and determining a certain behaviour strategy in their labour activity. …”
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A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis by Sadia Islam Tonni, Md. Alif Sheakh, Mst. Sazia Tahosin, Md. Zahid Hasan, Taslima Ferdaus Shuva, Touhid Bhuiyan, Muhammad Ali Abdullah Almoyad, Nabil Anan Orka, Md. Tanvir Rahman, Risala Tasin Khan, M. Shamim Kaiser, Mohammad Ali Moni

“…This study introduces an optimized hybrid transfer learning (TL) framework for brain tumor classification using magnetic resonance imaging images. …”
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Development of an accurate and sensitive assay for 2-methoxyestradiol using derivatization and liquid chromatography-tandem mass spectrometry by Koji Takahashi, Masaki Takiwaki, Seketsu Fukuzawa, Yoshikuni Kikutani, Kentaro Abe, Tatsuya Higashi, Hironori Kobayashi

“…These findings demonstrated that this LC-MS/MS method combined with the MPDNP-F derivatization can provide accurate and highly sensitive quantification of 2ME.…”
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Salidroside alleviates Aβ1–42-induced ferroptosis in human neuroblastoma cells by AKT/GSK-3β activation via inhibiting VDAC1 by Bensi Zhang, Xiujun Zhang, Waleephan Treebuphachatsakul, Rungusa Pantan, Natnicha Kampan, Manussabhorn Phatsara, Chun Shi, Suteera Narakornsak

“…The expression of ferroptosis-related proteins, VDAC1, and AKT/GSK-3β signaling pathway-related proteins was detected by western blotting; the Fe²⁺ content of cells was determined by an iron content assay kit; the level of ROS in cells was detected by immunofluorescence; and apoptosis was detected by flow cytometry. …”
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Intestinal Cells-on-Chip for Permeability Studies by Marit Keuper-Navis, Hossein Eslami Amirabadi, Joanne Donkers, Markus Walles, Birk Poller, Bo Heming, Lisanne Pieters, Bjorn de Wagenaar, Adam Myszczyszyn, Theo Sinnige, Bart Spee, Rosalinde Masereeuw, Evita van de Steeg

“…Intestine-on-chip systems hold considerable promise as testing platforms, but several characteristics still require optimization and further development. Methods: An established intestine-on-chip model for tissue explants was adopted for intestinal cell monolayer culture. …”
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Determination of biologically active substances extraction parameters from cranberry leaves by I. K. Vlasova, O. M. Koshovyi, O. S. Kukhtenko, M. A. Komisarenko, Т. V. Ilina, A. M. Kovalyova

“…Pursh) for creating a new dry extract with hypoglycemic activity. Materials and methods. The object of the study was cranberry leaves. …”
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Establishing translational performance standards for TB therapy using rifampicin-based regimens in a male and female high-burden murine model by Jason E. Cummings, Lisa Woolhiser, Barbara Graham, Gregory T. Robertson, M. Nurul Islam, Richard A. Slayden

“…Abstract Background Establishing efficacy benchmarks in preclinical tuberculosis (TB) models is essential for optimizing and prioritizing therapeutic regimens. However, standardized classification methods for comparing high-performing regimens are currently lacking. …”
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The safety of cyclosporine and tacrolimus in pediatric nephrotic syndrome patients: a disproportionate analysis based on the FAERS database by Yu Liu, Chong Yan, Yaowang Zhao, Sui Deng, Jiancheng Zu

“…We employed three signal detection methods—Proportional Reporting Ratio (PRR), Relative Reporting Ratio (RRR), and Reporting Odds Ratio (ROR)—to assess the risk of drug-related AEs. …”
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Effective intervention of brucellosis prevention in developing countries: A dynamic modelling study by Han Ni, Haoyun Dai, Xuewen Yang, Jin Zhao, Yuxi He, Shanghui Yi, Xiuqin Hong, Wenting Zha, Yuan Lv

“…These results can provide an important reference for optimizing brucellosis intervention plans.…”
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Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation by Vedat Cicek, Sahhan Kilic, Selami Dogan, Almina Erdem, Mert Babaoglu, Irem Yilmaz, Salih Karaismail, Murat Mert Atmaca, Mert Ilker Hayiroglu, Tufan Cinar, Ulas Bagci

“…CAR was identified as the optimal score for the prediction of LAT in patients with stroke and without AF.…”
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Bridge service life and impact of maintenance events on the structural state index by Abdoul S. Bah, Yan Zhang, Kotaro Sasai, David Conciatori, Luc Chouinard, Nicolas Zufferey, Gabriel J. Power, Thomas Sanchez, Xuande Chen

“…Currently, planning and decisions on maintenance activities are based on condition assessment methods that rely primarily on visual inspections. …”
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MODELING LONGITUDINAL MEASUREMENTS OF CLINICAL AND EPIDEMIOLOGICAL PARAMETERS USING JOINPOINT REGRESSION by Mihaela Moscalu, Ionela-Lăcrămioara Șerban, Norin Forna, Mihaela Pundiche, Loredana Mitran, Madalina-Elena Datcu, Nicolae Șerban Dragomir, Alin Constantin Pînzariu

“…In this context, analytical methods capable of detecting and interpreting temporal changes in clinical parameters have become essential. …”
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