Inter-assay variability in the measurement of urinary C-terminal cross-linked telopeptide of type II collagen following anterior cruciate ligament reconstruction by Lachlan M. Batty, Kate E. Webster, Natasha Vassileff, Jereme G. Spiers, Haydn J. Klemm, Brian Devitt, Timothy S. Whitehead, Andrew F. Hill, Julian A. Feller

“…The specific assay used is critical to consider when interpreting results and has implications for pooling data and meta-analysis.…”
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The Extended Flexor Carpi Radialis Approach for Distal Radius Fracture Fixation: A Prospective Study by Sulaiman Alrefai, MD, Dionne Hsu, MD(c), Jonathan Persitz, MD, Atefeh Noori, PhD, Andrea Chan, MD, FRCSC, Ryan Paul, MD, FRCSC

“…A retrospective review of prospectively collected data was conducted including wrist range of motion, grip strength, Disabilities of Arm, Shoulder, and Hand scores, and complications. …”
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Effectiveness of CONUT and NRI as nutritional risk screening tools in peritoneal dialysis: a multicenter study by Wenlong Qiu, Wenlong Qiu, Rui Chu, Rui Chu, Yaqi Ma, Yaqi Ma, Jiaxin Xue, Jiaxin Xue, Qingdong Xu, Yueqiang Wen, Xiaojiang Zhan, Fenfen Peng, Xiaoyang Wang, Juan Wu, Ning Su, Xiaoran Feng, Xingming Tang, Xianfeng Wu, Qian Zhou, Na Tian, Na Tian

“…Statistical analyses included log-rank tests, Cox regression models and the receiver operating characteristic curves to evaluate the association between nutritional risk and mortality.ResultsOur findings revealed that 76.58% of patients were classified as having nutritional risk according to the CONUT score, while 79.10% by the NRI. …”
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Comprehensive pre- and in-hospital near-infrared-spectroscopy (NIRS) monitoring after return of spontaneous circulation predicts neurological outcome following out-of-hospital card... by Sebastian Schnaubelt, Sebastian Schnaubelt, Sebastian Schnaubelt, Andrea Kornfehl, Felix Eibensteiner, Christoph Schriefl, Florian B. Mayr, Patrick Aigner, Mathias Gatterbauer, Michael Girsa, Daniel Grassmann, Daniel Grassmann, Andreas Zajicek, Alexander Spiel, Wolfgang Schreiber, Wolfgang Schreiber, Michael Holzer, Heidrun Losert, Mario Krammel, Mario Krammel, Thomas Uray

“…NIRS values were then compared between patients with favorable and non-favorable neurological outcomes, and cutoff values were assessed via receiver operating characteristic (ROC) and Classification and Regression Trees (CART) analyses. …”
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Prevalence of non-fatal injuries and associated factors in Mbarara Municipality, Western Uganda, December 2016-June 2017 by Rebecca Nuwematsiko, Angela Nakanwagi Kisakye, David Musoke, Delia Bandoh, Lillian Bulage, Olufemi Olamide Ajumobi, Frederick Oporia, Fiston Muneza, Nino Paichadze, George Pariyo, Abdulgafoor Bachani, Olive Kobusingye, Kenneth Mugwanya, John Ssempebwa

“…The most recent non-fatal injury (within a six-month recall period; December 2016 to June 2017) resulting in loss of at least one day of usual daily operating activity was considered. We conducted a descriptive statistical analysis to estimate the counts and frequencies of non-fatal injuries. …”
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How to Implement Digital Clinical Consultations in UK Maternity Care: the ARM@DA Realist Review by Catrin Evans, Georgia Clancy, Kerry Evans, Andrew Booth, Benash Nazmeen, Candice Sunney, Mark Clowes, Nia Wyn Jones, Stephen Timmons, Helen Spiby

“…The review had three iterative phases: (1) refining the review focus and developing initial programme theories; (2) retrieval of evidence for data extraction and analysis (using on a realist logic to identify key contexts, mechanisms and outcomes); and (3) testing and refining the programme theories. …”
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A nomogram for predicting unfavorable outcomes of antituberculosis treatment among individuals with AIDS combined with pulmonary tuberculosis in China by Xiaoxu Han, Xiaoxu Han, Jin Sun, Jin Sun, Yuan Gao, Yuan Gao, Hongxia Yan, Hongxia Yan, Xiangchuan He, Yuanyuan Ma, Peng Xu, Peng Xu, Ning Ding, Ning Ding, Xin Zhang, Xin Zhang, Meixin Ren, Meixin Ren, Taiyi Jiang, Taiyi Jiang, Tong Zhang, Tong Zhang, Bin Su, Bin Su, Bin Su, Bin Su

“…Decision curve analysis (DCA) was used to assess the clinical applicability of the prognostic models. …”
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Unlocking winter maize potential: pioneering on-farm strategies for resilient yields in challenging climates by Raj Kumar Jat, Shubham Durgude, Vijay Singh Meena, Vijay Singh Meena, RK Sohane, RN Singh, Illathur R. Reddy, Suneel Kumar, S. Pazhanismy, Sunita Kumari Meena, Kumari Sharda, Susheel Singh, Rama Kant Singh, Rama Kant Singh, Seema Kumari, Seema Kumari, Pankaj Kumar, Govind Kumar, Amit Kumar Lenka, Asheesh Chaurasiya, Anup Das, Anil Kumar Jha, Dhananjay Pati Tripathi, Swati Sagar

“…Principal component analysis (PCA) underlined the role of integrated agronomic practices in maximizing maize production. …”
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Cross-frequency coupling between low frequency and gamma oscillations altered in cognitive biotype of depression by Hongli Wang, Hongli Wang, Xiaoning Shi, Xiaoning Shi, Chenyang Wang, Chenyang Wang, Yongsheng Qi, Michel Gao, Yingying Zhao, Yingying Zhao

“…Cross-frequency coupling between low frequency and gamma oscillations were analyzed using specific computational methods based on the data collected by Electroencephalogram (EEG). Furthermore, we did correlation analysis to explore the relationship between cross-frequency coupling of neural oscillations with cognitive function in depression.ResultsWe found that phase-amplitude coupling (PAC) values decreased in cognitive biotype. …”
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The clinical value of the neutrophil-to-lymphocyte ratio, systemic immune-inflammation index, monocyte-to-lymphocyte ratio and platelet-to-lymphocyte ratio for predicting the sever... by Xin Zhao, Fen Wu, Shunfeng Zhao, Wenna Chen, Wei Si, Yuanrui Li, Dengke Zhang, Jing Wang, Ningning Wang, Lina Sun, Zhiyu Sun, Haoxiao Chang, Ganqin Du

“…The result of receiver operating characteristic (ROC) analysis showed that NLR was the best predictor of ICU admission for AE patients (AUC = 0.701). …”
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To elucidate the neuroprotective effect of omega-3 fatty acid supplementation in acute spinal cord injury subjects: A prospective longitudinal cohort study by Khurshid Alam Ansari, Priyank Pratap, Zeenat Ara, Muhammad Shahid Raza, Sharad Verma, Shah Waliullah, Mohd Yoosuf

“…Result: In our study, the omega-3 fatty acid-supplemented group showed gradual increasing trends in subsequent follow-ups, and the difference was statistically significant (P<0.0001*), whereas receiver-operating characteristic analysis of omega-3 levels between cases (at different follow-ups) and controls, a significant cutoff value of 3.90 with a sensitivity of 92.31% and specificity of 84.62% was observed. …”
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Cardiometabolic risk assessment by anthropometric and biochemical indices in mexican population by Luz Quirino-Vela, Miguel Mayoral-Chavez, Yobana Pérez-Cervera, Yobana Pérez-Cervera, Osiris Ildefonso-García, Elizabeth Cruz-Altamirano, Monserrat Ruiz-García, Juan Alpuche

“…Anthropometric indices, including body mass index (BMI), waist-to-height ratio (WHtR), body roundness index (BRI), deep abdominal adipose tissue index (DAAT), and weight-adjusted waist index (WWI), were calculated alongside biochemical indices such as HOMA-IR, triglyceride-glucose index (TG), and combined indices like TG*BMI and TG*WC. Receiver operating characteristic (ROC) curve analysis evaluates diagnostic performance, with sex-stratified analyses conducted to determine optimal cut-off values.ResultsNon-conventional indices demonstrated superior diagnostic performance across all outcomes. …”
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Colorectal carcinoma: Evaluation of systemic values of interleukin-1 and interleukin-33 in patients with and without thrombocytosis by Jocić Miodrag, Gajović Nevena, Jurišević Milena, Jovanović Marina, Zdravković Nataša, Arsenijević Nebojša, Vuković-Dejanović Vesna, Marić Veljko, Milev Boško, Jovanović Milan

“…IL-1/IL-12 (p = 0.016), IL-1/IFN-γ (p = 0.007), IL-1/IL-17 (p = 0.006), IL-33/IL- 12 (p = 0.001), IL-33/IFN-γ (p = 0.001), IL-33/IL-17 (p = 0.002), and IL-33/IL-1 (p = 0.006) ratios were significantly higher in CRC patients with thrombocytosis in comparison to CRC patients without thrombocytosis. Analysis of Receiver Operating Characteristic (ROC) curves showed that values of IL-1 [area under curve (AUC) = 0.718; 95% confidence interval (CI): 0.567–0.868; sensitivity 69.2%, specificity 62.9%] and IL-33 (AUC = 0.763; 95% CI: 0.614– 0.911; sensitivity 84.6%, specificity 65.7%)], could be serve as possible markers for paraneoplastic thrombocytosis in CRC patients. …”
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Clinical outcomes of double-flap technique versus gastric tube reconstruction following laparoscopic proximal gastrectomy: a multicenter propensity score-matched cohort study by Zhu Jingtao, Chen Shaoqin, Zhang Tao, Yang Li, You Sheng, Hong Qingqi, Lin Hexin, Chen Yinan, Yu Huangdao, Chen Yifu, Yu Xuejun, You Jun

“…Results After 1:1 PSM, 41 patients were included in each group for analysis. Compared to the LPG-GT group, the LPG-DFT group had a longer operation time (340.0 min vs. 280.0 min, P < 0.001) but less intraoperative blood loss (80.0 ml vs. 100.0 ml, P < 0.001), a shorter time to nasogastric tube removal (3.0 days vs. 5.0 days, P < 0.001), and shorter postoperative hospital stay (9.0 days vs. 12.0 days, P < 0.001). …”
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Hand Grip Strength Cut‐Off Points as a Discriminator of Sarcopenia and Sarcopenic Obesity: Results from the ELSA‐Brasil Cohort by Clarice Alves Santos, Helena Fraga Maia, Francisco José Gondim Pitanga, Maria da Conceição Chagas deAlmeida, Maria de Jesus Mendes daFonseca, Estela Mota Leão deAquino, Letícia de Oliveira Cardoso, Rosane Harter Griep, Sandhi Maria Barreto, Claudia Kimie Suemoto, Paulo Lotufo, Isabela Bensenor, Sheila Maria Alvim deMatos

“…The outcomes were classified based on the skeletal muscle mass index (BMI/height2) and fat percentage, estimated from the bioimpedance analysis data. Sensitivity, specificity and Brier score were calculated for each estimated HGS cut‐off point. …”
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Centrifugation versus filtration-based cell salvage: impact on perioperative bleeding in cardiac surgery—the COLTRANE randomised clinical trial – study protocol by Christine Mouton, Nicolas Nesseler, Antoine Bénard, Mathieu Pernot, Alexandre Ouattara, Antoine Beurton, Alexandre Mansour, Victor-emmanuel Brett, Corinne Batsale, Anais Aitgougam, Anais Cordon, Aurelie Fresselinat, Geraldine Robert, Julien Imbault

“…The main objective is to determine whether the filtration-based SAME device reduces significant perioperative bleeding compared with the centrifugation-based system in high-risk cardiac surgery patients.Methods and analysis The Centrifugation-based vs filtration-based intraOperative cell saLvage on qualiTy of peRioperAtive haemostasis iN cardiac surgEry (COLTRANE) trial is a multicentre, parallel-group, single-blinded, superiority-randomised clinical trial. …”
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Cardiometabolic index predicts cardiovascular events in aging population: a machine learning-based risk prediction framework from a large-scale longitudinal study by Yuanxi Luo, Yuanxi Luo, Zhiyang Yin, Xin Li, Xin Li, Chong Sheng, Ping Zhang, Dongjin Wang, Dongjin Wang, Yunxing Xue

“…Multivariate Cox regression analysis, adjusting for potential confounders, confirmed a significant association between CMI and CVD risk. …”
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Impact factor selection for non-fatal occupational injuries among manufacturing workers by LASSO regression by Yingheng XIAO, Chunhua LU, Juan QIAN, Ying CHEN, Yishuo GU, Zeyun YANG, Daozheng DING, Liping LI, Xiaojun ZHU

“…MethodsA total of 2243 frontline workers from cable and shipbuilding enterprises were selected as study subjects to investigate the incidence of non-fatal occupational injuries and collect information at four levels: individual, equipment, management, and environment in past 12 months. Data balancing was performed using resampling, and LASSO regression was used to select factors of non-fatal occupational injuries. …”
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Derivação ventriculoatrial no tratamento da hidrocefalia em crianças Ventriculoatrial shunts in the treatment of hydrocephalus in children by Gilberto Machado de Almeida

“…Up to the present time (December-1967) a total of 72 children are alive, showing a compensated hydrocephalus and 30 patients died, being impossible to obtain a follow-up of the 34 remaining cases. After the analysis of the operatory conditions, of the complications and of the results, the folloying conclusions are withdrawn: 1) the ocurrence of pulmonary tromboembolic complications is quite rare after ventriculoatrial shunts, justifying the use of this technique for the treatment of hydrocephaly till others forms of treatment are available; 2) periodic cardiologic examinations should be performed in patients submitted to ventriculo-venous shunts in order to prevent right cardiac insuficiency; 3) the prevention of infectious complications and selection of the cases are fundamental for better post-operative results; 4) the physician responsible for treatment of hydrocephalic patients should warn the parents regarding the possibility of new sirguical interventions and be ready to re-operate as many times as necessary; 5) there is not justifycable the replacement of the atrial tube when its extremity reaches the level of the fourth thoracic vertebra; 6) there is not correct the assertion that an shunt has to remain always with the drainage process working fully; 7) in order to evaluate the prognosis of the mental development of the hydrocephalic patients, a group of data has to be considered as a whole, namely the neurological examination, cranial transilumination, etiology of the disease, electroencephalo-graphic tracings, Gesell test and, if possible, the measurement of the cerebral mantle; 8) a normal psychological development (IQ greater than 85) can be expected in about 40% of the patients with controled hydrocephalus.…”
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Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review by Rhiannon Evans, Sarah MacDonald, Robert Trubey, Jane Noyes, Michael Robling, Simone Willis, Soo Vinnicombe, Maria Boffey, Charlotte Wooders, Asmaa El-Banna, GJ Melendez-Torres

“…First, we integrated the synthesis of thin and rich process evaluations (RQ3–4) with outcome data to explain intervention effectiveness and variations in effects (RQ2). …”
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