Effects of 18 Months of Growth Hormone Replacement Therapy on Bone Mineral Density in Patients with Adult Growth Hormone Deficiency: A Retrospective Study by Ya-Yin Shen, Jia-Ni Ma, Zi-Yu Ren, Jie Liu, Xin-Yi Zhou, Xue-Rui Xie, Wei Ren

“…Objective. The effect of physiological dose growth hormone (GH) replacement therapy on bone mineral density (BMD) in adults with growth hormone deficiency (GHD) is not well defined. …”
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Interim Analysis of Treatment Outcomes of Young Children with 5q Spinal Muscular Atrophy on Gene Replacement Therapy with Onasemnogene Abeparvovec. Clinical Observations by Anna A. Kokorina, Sergei S. Nikitin

“…Onasemnogene abeparvovec is the first gene replacement therapy medication based on the adeno-associated viral vector (AAV9). …”
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Optimizing Bioceramic Composites for Hip Joint Replacements using SPS Method: Investigating the Effects of Titanium Diboride (TiB2) on Tribological Properties by Pavankumar Ravikumar, Goud Mallesh, S. Suresh Kumar, H. S. Manjunatha

“…The objective was to enhance mechanical strength, wear resistance, and biocompatibility for long-term orthopedic applications. …”
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Associations between new-onset postoperative atrial fibrillation and changes in left ventricular mass index in patients undergoing transcatheter aortic valve replacement by Hua-Jie Zheng, Jun Li, Ling-Feng Tang, Mei Guo, Ya-Nan Wei, Wei Cheng

“…Objectives To investigate the impact of POAF on cardiac remodeling and its association with clinical outcomes after TAVR. …”
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Comparison of clinical pregnancy rates between hormone replacement therapy and modified natural cycle for endometrial preparation in frozen embryo transfer cycles: An RCT by Farnaz Safarloo, Marzieh Zamaniyan, Eisa Nazar, Keshvar Samadaee Gelehkolaee, Mahboubeh Omid, Sepideh Peivandi

“… Background: Frozen-thawed embryo transfer (FET) during the endometrial receptivity window is important for implantation. Objective: This study aims to compare the clinical pregnancy rate in 2 methods of endometrial preparation in FET using the hormone replacement cycle (HRC) and the modified natural cycle (mNC). …”
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The prognostic impact of net ultrafiltration intensity in critically ill patients receiving continuous renal replacement therapy: a multivariable and propensity-matched analysis by Lu Jin, Peiyun Li, Youli Tang, Wanhong Yin, Fang Wang, Ling Zhang

“…Objectives Net ultrafiltration (UFnet) is widely used for fluid management during continuous renal replacement therapy (CRRT) for critically ill patients over extended periods. …”
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International normalized ratio measurement during perioperative anticoagulation bridging with low-molecular-weight heparin in patients undergoing heart valve replacement surgery by Liza Rijvers, Sanna R. Rijpma, Herbert B. van Wetten, Yvonne M.C. Henskens, An K. Stroobants

“…Methods: Thirty-eight anticoagulated patients on VKA undergoing valve replacement surgery were studied using 2 plasma-based INR assays and 1 whole blood point-of-care INR method at multiple time points after postoperatively resuming VKA. …”
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Efficacy of sivelestat in alleviating postoperative pulmonary injury in patients with acute aortic dissection undergoing total arch replacement: a retrospective cohort study by Zhiyan Mai, Xudong Liu, Weixun Duan, Chen Yang, Yenong Zhou, Tao Chen, Zheng Su, Yang Yang, Jincheng Liu, Zhenxiao Jin

“…Abstract Objective Sivelestat may reduce postoperative pulmonary injury after total arch replacement (TAR). …”
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What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis by Rachael Gooberman-Hill, Michael R Whitehouse, Hung-Yuan Cheng, Andrew David Beswick, Vikki Wylde, Wendy Bertram, Mohammad Ammar Siddiqui

“…Objectives To update our previous systematic review to synthesise latest data on the prevalence of long-term pain in patients who underwent total hip replacement (THR) or total knee replacement (TKR). …”
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MODERN APPROACHES TO THERAPY FOR CHILDREN WITH MUCOPOLYSACCHARIDOSIS by N. V. Buchinskaya, I. А. Chikova, E. А. Isupova, О. V. Kalashnikova, М. М. Kostik, V. G. Chasnyk

“…Background: Research objective was to study the influence of enzyme replacement therapy on a somatic state and psychomotor development of children with mucopolysaccharidosis type I and II of various severity in dynamics and to estimate its efficiency. …”
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Compliant Tibial Stem for Primary Total Knee Arthroplasty by Armin W. Pomeroy, Alexander Upfill-Brown, Brandon T. Peterson, Dean Chen, Joel Weisenburger, Alexandra Stavrakis, Hani Haider, Nelson F. SooHoo, Jonathan B. Hopkins, Tyler R. Clites

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Antibacterial therapy of sepsis in extracorporeal detoxication: current problems and ways to solve them by A. V. Marukhov, M. V. Zakharov, N. V. Chubchenko, A. N. Belskikh, L. V. Buryakova, D. Yu. Lazarenko

“…Impaired renal function and renal replacement therapy lead to a significant change in the pharmacokinetic parameters of most intravenous antibacterial drugs, which in many cases is accompanied by insufficient or excessive concentration in the blood which results in antibacterial therapy failure. …”
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Prevalence of acute kidney injury in Mexico; a systematic review and meta-analysis of pre-pandemic reports by Jose J. Zaragoza, Jonathan S. Chavez-Iñiguez, Armando Vazquez-Rangel

“…There is little available information regarding the characteristics and incidence of AKI in Latin America (LA), especially in Mexico.Objectives Systematically search the literature and perform a meta-analysis of the epidemiology of AKI in Mexico, to provide data on AKI and kidney replacement therapy (KRT) that would contribute to general knowledge in this matter.Methods We performed a systematic search for articles in pediatric and adult patients admitted to the general ward, Emergency Room or Intensive Care Unit published between January 1, 2000, and September 30, 2024. …”
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Single center experience with surgically implanted Melody and Sapien 3 valves in the mitral position in young children by Hüseyin Sicim, Mohamad Alaeddine, Daniel A. Velez

“…ObjectivesMitral valve replacement in young children is a challenging situation due to limited options. …”
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Association between type III collagen degradation and local tissue damage of a single joint by Christian S. Thudium, Sten Rasmussen, Morten A. Karsdal, Anne-Christine Bay-Jensen

“…Objective: The development of disease-modifying drugs is limited by OA's heterogeneity and the challenge of defining clinical endpoints. …”
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Clinical and economic analysis as an instrument for harmonizing import substitution in the preferential segment of medicinal support by E. V. Eliseeva, E. S. Maneeva, R. K. Goncharova, A. V. Kropotov

“…The authors suggest that the reduced replacement of the imported drugs can be explained by both objective (the actual absence of the respective Russia-made analogues) and subjective (irrational approaches to the procurement of medicines due to the lack of an appropriate algorithm). …”
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An observational study of haemophilia A patients without inhibitors using the French national claims (SNDS) database by Marc Trossaërt, Aletta Falk, Laurène Gautier, Nana Kragh, Olivia Van Hinloopen, Remi Varin

“…Objectives: To describe clinical characteristics, factor consumption, and events of interest in patients with haemophilia A without inhibitors receiving prophylaxis in France, and the clinical impact of switching to Elocta® in this population.Methods: This retrospective, observational study using the Système National des Données de Santé database, analysed data from patients with haemophilia A without inhibitors using prophylactic factor VIII (FVIII) replacement therapy during 2016–2019. …”
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Effect of electroacupuncture stimulation combined with the enhanced recovery after surgery regimen on motor function recovery following total knee arthroplasty by Shiqiang Ma, Jun Dong, Zhengxin Meng, Yunchao Zhao, Qiuling Shi, Donghui Guo

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Early outcomes of aortic valve neocuspidization (the Ozaki procedure): Initial experience of a single centre by Ranajit Naik, Abhishek Prabhu, Mohan Gan, Richard Saldanha

“…Objectives: To evaluate the immediate and early outcomes of our initial experience with the AVNeo procedure in a spectrum of aortic valve diseases. …”
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Impact of personality traits on activities of daily living in patient-reported outcomes one and six months after total knee arthroplasty: a cohort study by Keigo Nanjo, Takashi Ikeda, Ryutaku Kaneyama, Tomoko Sakai, Tetsuya Jinno

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