FLASH radiotherapy: bridging revolutionary mechanisms and clinical frontiers in cancer treatment – a narrative review by Jae Sik Kim, Hak Jae Kim

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Muscle-sparing aortic coarctation repairCentral MessagePerspective by Stephanie G. Berset, MD, Hitendu Dave, MD, Christian Balmer, MD, Anna Nowacka, Raymond Pfister, MD, Patrick O. Myers, MD, René Prêtre, MD

“…Objective: Surgery for aortic coarctation repair provides excellent hemodynamic results but may be complicated by musculoskeletal issues. The purpose of the study was to determine the midterm results of a muscle-sparing surgical approach to aortic coarctation repair, with special emphasis on the repair and on the musculoskeletal changes associated with a posterior thoracotomy. …”
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REHABILITATION OF REPRODUCTIVE FUNCTION IN YOUNG ONCOLOGIC PATIENTS AFTER THE ORGAN-SPARING TREATMENT (BRIEF COMMUNICATION) by E. A. Chulkova

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Glycemic Control in Patients with Diabetes on Peritoneal Dialysis: From Glucose Sparing Approach to Glucose Monitoring by Aleksandra Kezić, Selena Gajić, Ana Račić Ostojić, Ivana Bekić, Ana Bontić, Jelena Pavlović, Marko Baralić, Ljiljana Popović

“…This glucose-sparing approach not only reduces the glucose load and improves glycoregulation with correction of the lipid profile but also maintains the viability of the peritoneal membrane by reducing the harmful effects of GDPs.…”
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High-Intensity Focused Ultrasound (HIFU) Treatment of Vulvar Lichen Sclerosus by Calik J, Woźniak B, Murawski M, Donizy P, Sauer N

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Targeting B7-H3 in solid tumors: Development and evaluation of novel CAR-T Cell therapy by Ning Li, Chunhua Zhang, Xiaoyu Li, Shufen Liu, Youhua Xu, Xifei Yang

“…The B7-H3 CAR-T cells exhibited robust and selective cytotoxicity against B7-H3-positive tumor cells, sparing normal tissues. In preclinical animal models, these cells significantly inhibited tumor growth, demonstrating higher targeting specificity and preferential accumulation in tumor sites. …”
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Bacteriophage-based strategies for biocontrol and treatment of infectious diseases by Trinh Thi Trang Nhung, Swati Verma, Saravanaraman Ponne, Gautam Kumar Meghwanshi, Thomas Schön, Rajender Kumar

“…The ability of bacteriophages to specifically target pathogenic bacteria while sparing the normal flora makes them attractive treatment options. …”
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Managing RS3PE: Diagnostic approach, initial steroid response, and long-term management with DMARDs by Dasi Sharath Chandra, Devipriya Surapaneni, C. Saranya

“…However, recurrence of symptoms occurred upon discharge, prompting the introduction of steroid-sparing agents: methotrexate and hydroxychloroquine, alongside continued oral steroid treatment. …”
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Reduction of subclinical acute cardiac injury through DIBH radiotherapy: a single-institution real-world clinical cohort analysis by Kun Zhang, Jing Shen, Yongguang Liang, Xiangyin Meng, Bo Yang, Jiabin Ma, Ke Hu, Jie Qiu, Xiaorong Hou, Fuquan Zhang

“…However, the issue of whether dosimetric advantages can be effectively translated into clinically measurable benefits for patients remains to be further elucidated. …”
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Multi-Response Au-Nanohybrid Composite Triggered NIR-Light for Effective Anti-Tumor Therapy in Animal Model by Kong LZ, Zhou D, Mo G, Shu M, Yu W, Cheng H, Li K

“…While targeted nanomedicines are highly regarded for their potential, they are not spared from issues of colloidal instability and uncontrolled drug release.Methods: The hybrid system (Au@SiO2-HA-DOX) was designed to enhance colloidal stability and facilitate controlled drug delivery by coating gold nanorods with silica shells and hyaluronic acid (HA) for tumor targeting. …”
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