Factors affecting the use of neurally adjusted ventilatory assist in the adult critical care unit: a clinician survey by Fiona Reid, Nicholas Hart, Louise Rose, John Smith, Clare Harris, Victoria Cornelius, Gerrard Francis Rafferty, Daniel Hadfield, Clare Finney, Bethany Penhaligon, Sian Saha, Harriet Noble, Philip Anthony Hopkins

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Visual Cortical Function Changes After Perceptual Learning with Dichoptic Attention Tasks in Adults with Amblyopia: A Case Study Evaluated Using fMRI by Chuan Hou, Zhangziyi Zhou, Ismet Joan Uner, Spero C. Nicholas

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Intrathecal or intravenous AAV9-IDUA/RGX-111 at minimal effective dose prevents cardiac, skeletal and neurologic manifestations of murine MPS I by Lalitha R. Belur, Avery K. Huber, Hillary Mantone, Mason Robertson, Miles C. Smith, Andrea D. Karlen, Kelley F. Kitto, Li Ou, Chester B. Whitley, Elizabeth Braunlin, Justin Furcich, Troy C. Lund, Davis Seelig, Carolyn A. Fairbanks, Nicholas Buss, Kwi Hye Kim, R. Scott McIvor

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Environmental factors associated with general practitioner consultations for allergic rhinitis in London, England: a retrospective time series analysis by Roger Morbey, Obaghe Edeghere, Gillian Smith, Alex J Elliot, Andre Charlett, Shakoor Hajat, Dan Todkill, Felipe de Jesus Colon Gonzalez, Sari Kovats, Nicholas J Osborne, Rachel McInnes, Sotiris Vardoulakis, Karen Exley

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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcquire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

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Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. by William M Brandler, Andrew P Morris, David M Evans, Thomas S Scerri, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Susan M Ring, John Stein, Anthony P Monaco, Joel B Talcott, Simon E Fisher, Caleb Webber, Silvia Paracchini

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Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis-Study of Treatment’s Echocardiographic Mechanisms (CLOVERS-STEM) by Michael J. Lanspa, MD, Akram Khan, MD, Patrick G. Lyons, MD, Michelle N. Gong, MD, Ali A. Naqvi, MD, Siddharth Dugar, MD, Abhijit Duggal, MD, Nicholas J. Johnson, MD, Jacob H. Schoeneck, MD, Lane Smith, MD, PhD, Somnath Bose, MD, MPH, Nathan I. Shapiro, MD, Tatyana Shvilkina, DO, Danielle Groat, MStat, Jason R. Jacobs, PhD, Troy D. Olsen, RCDS, Steven Cannavina, RCDS, Daniel B. Knox, MD, Eliotte L. Hirshberg, MD, Wesley H. Self, MD, Samuel M. Brown, MD

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APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence by Jingyi Xie, Daniel G. Chen, William Chour, Rachel H. Ng, Rongyu Zhang, Dan Yuan, Jongchan Choi, Michaela McKasson, Pamela Troisch, Brett Smith, Lesley Jones, Andrew Webster, Yusuf Rasheed, Sarah Li, Rick Edmark, Sunga Hong, Kim M. Murray, Jennifer K. Logue, Nicholas M. Franko, Christopher G. Lausted, Brian Piening, Heather Algren, Julie Wallick, Andrew T. Magis, Kino Watanabe, Phil Mease, Philip D. Greenberg, Helen Chu, Jason D. Goldman, Yapeng Su, James R. Heath

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Azithromycin to prevent acute lower respiratory infections among Australian and New Zealand First Nations and Timorese children (PETAL trial): study protocol for a multicentre, int... by Anne B Chang, Keith Grimwood, Yuejen Zhao, Gabrielle B McCallum, Catherine A Byrnes, Heidi Smith-Vaughan, Peter S Morris, Christine Connors, Adrian Trenholme, Shirley Lawrence, Joshua Francis, Kobi L Schutz, Mark D Chatfield, Nevio Sarmento, Robyn L. Marsh, Emily R Bowden, Nicholas Fancourt, Adriano Vieira, Kim M Hare, Dennis Bonney, Felicity Marwick, Bronwyn Karvonen, Carolyn Maclennan, Milena Santos Lay, Endang Soares da Silva

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Call for emergency action to limit global temperature increases, restore biodiversity and protect health by Nicholas J Talley, Fiona Godlee, Lukoye Atwoli, Richard Smith, Thomas Benfield, Raffaella Bosurgi, Richard Horton, Carlos Augusto Monteiro, Kirsten Patrick, Peush Sahni, Abdullah H Baqui, Stephen Hancocks, Laurie Laybourn-Langton, Ian Norman, Nigel Praities, Marcel GM Olde Rikkert, Eric J Rubin, Sue Turale, Damián Vázquez

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Call for emergency action to limit global temperature increases, restore biodiversity and protect health by Nicholas J Talley, Fiona Godlee, Lukoye Atwoli, Richard Smith, Thomas Benfield, Raffaella Bosurgi, Richard Horton, Carlos Augusto Monteiro, Kirsten Patrick, Peush Sahni, Abdullah H Baqui, Stephen Hancocks, Laurie Laybourn-Langton, Ian Norman, Nigel Praities, Marcel GM Olde Rikkert, Eric J Rubin, Sue Turale, Damián Vázquez

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A protocol for a pilot randomised controlled trial of unguided internet cognitive behaviour therapy for grief in adolescents by Sarah J. Egan, Caitlin Munro, Sian B. Pauley-Gadd, Amy O'Brien, Thomas Callaghan, Nicholas Payne, Shravan Raghav, Bronwyn Myers, Christopher Hall, Hayden Wilson, Maarten C. Eisma, Paul A. Boelen, Kirsten V. Smith, Jennifer Wild, Michael Duffy, David Trickey, Elizabeth Bills, Lauren J. Breen

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Interactive and unimodal relationships between plant biomass, abiotic factors, and plant diversity in global grasslands by Marie Spohn, Sumanta Bagchi, Jonathan D. Bakker, Elizabeth T. Borer, Clinton Carbutt, Jane A. Catford, Christopher R. Dickman, Nico Eisenhauer, Anu Eskelinen, Nicole Hagenah, Yann Hautier, Sally E. Koerner, Kimberly J. Komatsu, Lauri Laanisto, Ylva Lekberg, Jason P. Martina, Holly Martinson, Meelis Pärtel, Pablo L. Peri, Anita C. Risch, Nicholas G. Smith, Carly Stevens, G. F. Ciska Veen, Risto Virtanen, Laura Yahdjian, Alyssa L. Young, Hillary S. Young, Eric W. Seabloom

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Correction: A personal sensing technology enabled service versus a digital psychoeducation control for primary care patients with depression and anxiety: a pilot randomized control... by Colleen Stiles-Shields, Karen M. Reyes, Tanvi Lakhtakia, Shannon R. Smith, Olga E. Barnas, Elizabeth L. Gray, Charles J. Krause, Kaylee P. Kruzan, Mary J. Kwasny, Zara Mir, Sameer Panjwani, Steven K. Rothschild, Lisa Sánchez-Johnsen, Nathan W. Winquist, Emily G. Lattie, Nicholas B. Allen, Madhu Reddy, David C. Mohr

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Can nebulised heparin reduce acute lung injury in patients with SARS‑CoV‑2 requiring advanced respiratory support in Ireland: the CHARTER‑Ireland phase Ib/IIa, randomised, parallel... by David Cosgrave, Bairbre McNicholas, Ciara Hanley, John Robert Sheehan, Padraig Calpin, Maeve Kernan, Darragh Murphy, Alberto Alvarez‑Iglesias, John Ferguson, Camilla Giacomini, Christine Greene, Catriona Cody, Shane McGeary, Marion Murphy, Marianne Fitzgerald, Gerard Curley, Barry Dixon, Roger J. Smith, Claire Masterson, Daniel O’Toole, Frank van Haren, John G. Laffey

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Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma by Ramses Sadek, Mohammed Milhem, Olivier Rixe, David Munn, Christopher M Smith, Yousef Zakharia, Joseph Drabick, Kenneth F Grossmann, Robert R McWilliams, Montaser F Shaheen, Ravindra Kolhe, Rafal Pacholczyk, Lucinda L Tennant, Eugene P Kennedy, Charles J Link Jr, Nicholas N Vahanian, Jiayi Yu, Steven S Shen, Erik L Brincks, Gabriela R Rossi

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Patients with neurological or psychiatric complications of COVID-19 have worse long-term functional outcomes: COVID-CNS—A multicentre case–control study by Rajish S. K. Shil, Adam Seed, Nkongho Egbe Franklyn, Brendan F. Sargent, Greta K. Wood, Yun Huang, Katherine C. Dodd, James B. Lilleker, Thomas A. Pollak, Sylviane Defres, Thomas M. Jenkins, Nicholas W. S. Davies, David A. Cousins, Michael S. Zandi, Thomas A. Jackson, Laura A. Benjamin, Ava Easton, Tom Solomon, John R. Bradley, Patrick F. Chinnery, Craig J. Smith, Timothy R. Nicholson, Alan Carson, Rhys H. Thomas, Mark Alexander Ellul, Nicholas W. Wood, Gerome Breen, Benedict Daniel Michael, the COVID-CNS Study Group

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Atacama Large Aperture Submillimeter Telescope (AtLAST) Science: Planetary and Cometary Atmospheres [version 2; peer review: 3 approved] by Conor Nixon, Arielle Moullet, Nicholas Teanby, Imke de Pater, Steven Charnley, Bryan Butler, Pamela Klaassen, Raphael Moreno, Stefanie Milam, Mark Booth, Amelie Saintonge, Claudia Cicone, Martin Cordiner, Tony Mroczkowski, Doug Johnstone, Luca Di Mascolo, Minju Lee, Eelco van Kampen, Thomas Maccarone, Daizhong Liu, Matthew Smith, Sven Wedemeyer, Alexander Thelen, Thibault Cavalie, Leigh N. Fletcher, Richard Cosentino, Katherine de Kleer, Mark Gurwell, Emmanuel Lellouch, Yi-Jehng Kuan

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Safety and immunogenicity of an optimized self-replicating RNA platform for low dose or single dose vaccine applications: a randomized, open label Phase I study in healthy voluntee... by Christian J. Maine, Shigeki J. Miyake-Stoner, Darina S. Spasova, Gaelle Picarda, Annie C. Chou, Emily D. Brand, Melanie D. Olesiuk, Christine C. Domingo, Hunter J. Little, Thomas T. Goodman, Jacqueline L. Posy, Jasmin Gonzalez, Terrina L. Bayone, Jessica Sparks, Ebony N. Gary, Zhi Xiang, Nicholas J. Tursi, Casey E. Hojecki, Hildegund C. J. Ertl, David B. Weiner, Irafasha C. Casmil, Anna K. Blakney, Brandon Essink, Guillermo Somodevilla, Nathaniel S. Wang, Andrew J. Geall, Zelanna Goldberg, Parinaz Aliahmad

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A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer by Veronica Rendo, Michael Schubert, Nicholas Khuu, Maria F. Suarez Peredo Rodriguez, Declan Whyte, Xiao Ling, Anouk van den Brink, Kaimeng Huang, Michelle Swift, Yizhou He, Johanna Zerbib, Ross Smith, Jonne Raaijmakers, Pratiti Bandopadhayay, Lillian M. Guenther, Justin H. Hwang, Amanda Iniguez, Susan Moody, Ji-Heui Seo, Elizabeth H. Stover, Levi Garraway, William C. Hahn, Kimberly Stegmaier, René H. Medema, Dipanjan Chowdhury, Maria Colomé-Tatché, Uri Ben-David, Rameen Beroukhim, Floris Foijer

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