Low‐Frequency Reconstruction for Full Waveform Inversion by Unsupervised Learning by Ningcheng Cui, Tao Lei, Wei Zhang

“…To overcome these challenges, we reconstructed an appropriate target data set that combines high, medium, and low‐frequency components and incorporated additional loss functions to enhance the network's output performance. …”
Get full text

Whole-exome sequencing screening for candidate genes and potential pathogenic variants associated with early-onset high myopia in 47 Chinese families by Xue Rui, Huiping Li, Runqing Ma, Shangying Yang, Yuanyuan lian, Wanyu Cheng, Meijiao Ma, Weining Rong, Xunlun Sheng

“…Protein–protein interaction (PPI) network analysis was conducted to detect interactions among candidate genes, and protein–protein docking was performed. …”
Get full text

The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis by Li Yan, Jiang-Han Li, Ai-Li Zhang, He Li, Bo Pang, De-Yang Meng, Qian Fu, Li-Juan Du, Yan Su

“…Patients with IPF were stratified into high- and low-risk cohorts. Finally, functional enrichment analysis, immune infiltration analysis, regulatory network construction, and reverse transcription quantitative PCR (RT-qPCR) were conducted separately to validate the findings. …”
Get full text

MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension. by Priyanka Nandakumar, Adrienne Tin, Megan L Grove, Jianzhong Ma, Eric Boerwinkle, Josef Coresh, Aravinda Chakravarti

“…We perform RNA sequencing of mRNA and microRNA and conducted differential expression and co-expression network analysis.…”
Get full text

Huqi formula suppresses hepatocellular carcinoma growth by modulating the PI3K/AKT/mTOR pathway and promoting T cell infiltration by Donghao Yin, Xiang Li, Xuemeng Yang, Xiaofei Shang, Zhen Li, Jiahao Geng, Yanyu Xu, Zijing Xu, Zixuan Wang, Zimeng Shang, Zhiyun Yang, Linlan Hu, Quanwei Li, Jiabo Wang, Xinhua Song, Xiuhui Li, Xiaojun Wang

“…Network pharmacology, RNA-Seq, molecular docking, Western blot, and flow cytometry were employed to assess the anti-HCC mechanisms. …”
Get full text

Status and trends in transcranial magnetic stimulation research: a bibliometric analysis by Qi Deng, Fei Xing, Dan Li, Dan Li, Maomao Huang, Maomao Huang, Zhangyu Xv, Yue Yang, Lei Li, Jiayi Zhu, Rongnan Shi, Guoya Meng, Qin Wang, Jianxiong Wang, Jianxiong Wang, Jianxiong Wang

“…BackgroundTranscranial magnetic stimulation (TMS), as a rapidly advancing non-invasive brain stimulation technique, has demonstrated reliable therapeutic efficacy and significant potential in brain function assessment and research. However, comprehensive bibliometric analyses of the overall TMS field remain limited. …”
Get full text

Automated experimental complex on the platform of modern ASCME by Omorov Turatbek, Asiev Abai, Osmonova Rima, Takyrbashev Beishenaly, Imanakunova Zgenishkul, Suerkulov Manas

“…The complex includes a physical model of the distribution network and the main functional elements of modern automated control and accounting systems for electricity (ASCAE), such as a data concentrator, a computer server, single-phase and three-phase electricity meters and a telecommunications module for transmitting and receiving data. …”
Get full text

Leverage point themes within Dutch municipalities' healthy weight approaches: A qualitative study from a systems perspective. by Maud J J Ter Bogt, Kirsten E Bevelander, Lisa Tholen, Gerard R M Molleman, Maria van den Muijsenbergh, Gerdine A J Fransen

“…Such an approach has four interconnected system levels: events, structures, goals, and beliefs, in which small changes ('leverage points') can lead to substantial changes in the functioning of the entire system. The current research examined the functioning of five Dutch municipalities' healthy weight approaches (HWAs) and the leverage point themes that can be identified in their system.…”
Get full text

Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway by Yuan X, Long L, Wang M, Chen W, Liang B, Xu L, Wang W, Li C

“…Protein-protein interaction (PPI) network analysis prioritized 16 hub genes functionally enriched in oxidative stress (GO) and inflammatory/apoptotic pathways (HALLMARK). …”
Get full text

Age-Related Changes in Action Observation EEG Response and Its Effect on BCI Performance by Fukang Zeng, Xingyu Wen, Hongmei Tang, Guiyu Hu, Wensheng Hou, Xin Zhang

“…We employed task discriminant component analysis (TDCA) to decode observed actions and performed comprehensive analyses of prefrontal EEG responses, i.e. approximate entropy (ApEn), sample entropy (SamEn), and rhythm power ratios (RPR), and the whole-brain functional network. Regression analyses were subsequently conducted to analyze the effects on the classification accuracy. …”
Get full text

Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy by Fan J, Xu S, Zeng Y, Xu A, Wang X, Wang H, Kang P, Fu Y, Fan H, Zhou Y

“…A predictive model was constructed using four machine learning methods, and its performance was validated with independent datasets. A ceRNA regulatory network was established, and in vivo experiments were conducted using a DCM mouse model to validate key findings.Results: Nineteen DiGs were differentially expressed between DCM and controls. …”
Get full text

CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment by Mihály Hajós, Kiran Pandey, Annabelle C. Singer, Duc Duong, Sara Bitarafan, Monika Shpokayte, Zach Malchano, Ralph Kern, James J. Lah, Allan I. Levey, Nicholas T. Seyfried

“…Changes in protein expression were mapped to the consensus human AD protein network, representing co‐expressed and functionally linked modules linked to cell type and biochemical pathways. …”
Get full text

Comparative transcriptomic and proteomic analyses of hypoxia response in wild and cultivated tomato roots by Zhihan Zhang, Yabing Hou, Hao Yin, Song Lu, Daliang Liu, Lin Cheng, Houlin Yu, Tao Li, Yiyong Zhao

“…By analyzing the gene and protein networks of FZZ and T178 under hypoxic conditions, we inferred that T178 enhances hypoxia adaptation by forming more independent small modules and multilevel regulatory networks, whereas FZZ relies on a few large modules with limited functional diversity, resulting in weaker hypoxia tolerance. …”
Get full text

Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis by Zhao D, Zhuang J, Wang L, Wu L, Xu W, Zhao L, Hong J, Jin W, Miao C

“…Hub biomarkers were identified through a protein–protein interaction (PPI) network and validated using LPS-treated C57/BL6 mice. …”
Get full text

The effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes by Mohammad hossein Hashemzadeh, Farhad Rahmaninia, Payam Saidie

“…Therefore, considering the improvement in immune function markers under sleep deprivation with caffeine supplementation, even without enhancing anaerobic performance, and the fact that sleep deprivation strongly activates the body's inflammatory signaling network, the use of this supplement can be recommended for athletes in conditions of sleep deprivation and before intense activities.…”
Get full text

ACTIVE, ACTUATED, AND ASSISTIVE: A SCOPING REVIEW OF EXOSKELETONS FOR THE HANDS AND WRISTS by Angel Galbert, Arjan Buis

“…METHODOLOGY: The scoping review was conducted using the PRISMA-ScR guidelines. A systematic search was done on MEDLINE, EMBASE, Scopus, Web of Science, and NHS the Knowledge Network from inception to May 2023. …”
Get full text

Impacts of cigarette smoking on epistasis and gender-specific effects of FEV1/FVC ratio in human by Xu Changwei, Zhu Jun

“…The significant epistasis effects of these genes suggested the possibility of multiple functional polymorphisms. These associations offer mechanistic insight into pulmonary function regulation and networks between genetics factors and environmental factors, which indicate potential ways for interventions to COPD and many other respiratory diseases.…”
Get full text

Gut microbial metabolism of bile acids modifies the effect of Mediterranean diet interventions on cardiometabolic risk in a randomized controlled trial by Peipei Gao, Ehud Rinott, Danyue Dong, Zhendong Mei, Fenglei Wang, Yuxi Liu, Omer Kamer, Anat Yaskolka Meir, Kieran M. Tuohy, Matthias Blüher, Michael Stumvoll, Meir J. Stampfer, Iris Shai, Dong D. Wang

Get full text

Application of artificial intelligence technologies in HR management by S. V. Okladnikova, A. S. Pankrashov

“…Additionally, the process of applying the objective function to obtain a numerical coefficient based on individual metrics or a combination of them is described in order to make a decision corresponding to its value based on the resulting indicator of the function.Conclusion. …”
Get full text

Mechanistic insights into the cardiovascular effects of acute heat exposure: A multi-omics analysis based on a randomized crossover trial by Xinlei Zhu, Xihao Du, Yixiang Zhu, Lu Zhou, Cong Liu, Yue Niu, Qingli Zhang, Yixuan Jiang, Haidong Kan, Renjie Chen

“…The pathway enrichment was performed at the ingenuity pathway analysis platform. The network-based xMWAS analysis was further conducted. …”
Get full text