Joint analysis of whole-genome methylation and transcriptome in avian pullorum disease and validation of gene function by Jiongwen Wu, Weiming Liang, Aijun Liu, Xiaomeng Wang, Zhexia Fan, Xuerong Ma, Shuya Chen, Cheng Fang, Xiquan Zhang, Qingbin Luo

“…Abstract Pullorum disease caused by Salmonella pullorum can negatively affect growth and egg-laying performance, resulting in significant economic losses in poultry farming. …”
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Disturbed small-world networks and neurocognitive function in frontal lobe low-grade glioma patients. by Qingling Huang, Rui Zhang, Xinhua Hu, Shangwen Ding, Jingguang Qian, Ting Lei, Xuan Cao, Ling Tao, Zhiyu Qian, Hongyi Liu

“…We calculated the topological properties of brain functional networks in the 12 LGG, and compared with 12 healthy controls (HCs). …”
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Cognitive function and psychological well-being in older adults with sensorineural hearing loss: An Egyptian perspective by Heba G. Saber, Fathy N. Fatouh, Anas Askoura, Ghada O. Wassif, Enas R. Mohamed

“…Hearing impairment can lead to reduced social engagement, functional limitations, and a higher risk of depression, negatively impacting quality of life. …”
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Addiction Memory, Family Functioning, and Depression in Illicit Drug Users: Self-Esteem as a Mediator by Li Zeng, Xiaojun Zhou, Yuge Lei, Jiayan Chen

“…Addiction memory was positively correlated with depression (<i>β</i> = 0.195, <i>p</i> < 0.001), while family functioning negatively correlated with depression (<i>β</i> = −0.113, <i>p</i> = 0.008). …”
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fMRI insights into differential brain activation, executive function, and physical activity in older adults. by Huiqi Song, Jie Feng, Yingying Wang, Qichen Zhou, Chenglin Zhou, Jing Jin

“…<h4>Background</h4>Executive function is vital for cognitive health, particularly in older adults, where declines can lead to an increased risk of cognitive impairment. …”
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Functional trait response to aridity based on leaf trait network analysis in the Hexi Corridor, China by Yingxiang Miao, Haifeng Liu, James F. White, Guoqiang Wu, Shanjia Li

“…Structural equation modeling (SEM) was used to identify the direct and indirect effects of aridity and functional diversity (as measured by community weighted means and functional dispersion) on leaf nutrient concentration. …”
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Alterations in Human Hippocampus Subregions across the Lifespan: Reflections on White Matter Structure and Functional Connectivity by Jianling Tan, Zhongyan Wang, Yi Tang, Yin Tian

“…Then, FA analyses indicated that all effects of age on the hippocampal structures were nonlinear, and the white matter integrity of pHipp was higher than that of aHipp. In the functional-structural coupling, we found that the age-related FA of the right aHipp (aHipp.R) was negatively related to the FC. …”
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Relationship between plasma atherogenic index and thyroid function: evidence from NHANES 2007–2012 by Tianshu Li, Chunqiu Liu, Haoran Zhou, Hua Zhou

“…Abstract Thyroid function levels have been associated with a variety of metabolic disorders and correlate with blood lipid levels in vivo. …”
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Altered dynamic functional network connectivity in rheumatoid arthritis associated with peripheral inflammation and neuropsychiatric disorders by Lei Xie, Yanmin Zheng, Zhiduo Hou, Shuhua Ma, Zikai Huang, Jianhua Peng, Shuxin Huang, Ruiwei Guo, Jinzhuang Huang, Zhirong Lin, Zelin Zhuang, Jingjing Yin

“…Objective This study explored the dynamic functional connective (DFC) alterations in patients with rheumatoid arthritis (RA) and investigated the correlation between the neuropsychiatric symptoms, peripheral inflammation and DFC alterations.Method Using resting-state functional MRI, we investigated the DFC based on spatial independent component analysis and sliding window method for 30 patients with RA and 30 healthy controls (HCs). …”
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Correlation between serum magnesium and calcium ions and peripheral nerve function in chronic kidney disease by Zuo Xiao-li, Shang Hong-xue, Wang Yu-juan

“…Objective To explore the ionic levels of serum calcium(Ca²⁺)and magnesium(Mg²⁺)in patients with chronic kidney disease（CKD）and examine their correlations with peripheral nerve functions.Methods From October 2011 to October 2019,a total of 300 CKD patients were selected as subjects for this cross-sectional study.According to the glomerular filtration rate,they were divided into 1～5 stages.The serum levels of Ca²⁺ and Mg²⁺ were compared among different stages.Sensory and motor conduction latencies,conduction velocities,amplitudes of median and common peroneal nerves were measured and the correlations between parameters and serum levels of Ca²⁺ and Mg²⁺ analyzed.Results The serum levels of Ca²⁺ and Mg²⁺ in patients with CKD stage 1～3 were significantly higher than those in those with stage 4～5（P<0.05）and the incidence rates of hypocalcemia and hypermagnesemia in CKD stage 1～3 were significantly lower than those in stage 4～5（P<0.05）.The sensory and motor conduction latencies of median and common peroneal nerves in normal blood calcium and hypercalcemia group were lower than those in hypocalcemia group.SNCV and amplitude were higher than those in hypocalcemia group and motor conduction amplitudes of median and common peroneal nerves were higher in hypercalcemia group than those in normal blood calcium group（P<0.05）.The sensory and motor conduction latencies of median and common peroneal nerves were significantly lower in normal blood magnesium and hypermagnesemia groups than those in hypomagnesemia group.And sural nerve conduction velocity（SNCV）and amplitude were higher than those in hypomagnesemia group and motor conduction amplitude of common peroneal nerve was higher in hypermagnesemia group than that in normal blood magnesium group（P<0.05）.The sensory and motor conduction latencies of median nerve and common peroneal nerve of CKD patients were significantly negatively correlated（P<0.05）while SNCV and amplitude significantly positively correlated with serum levels of Ca²⁺ and Mg²⁺（P<0.05）.Conclusions CKD patients often have metabolic disorders of serum Ca²⁺ and Mg²⁺,which may have adverse effects on peripheral nerve function.…”
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Performance of the UNICEF/UN Washington Group tool for identifying functional difficulty in rural Zimbabwean children. by Thomas Frederick Dunne, Jaya Chandna, Florence Majo, Naume Tavengwa, Batsirai Mutasa, Bernard Chasekwa, Robert Ntozini, Andrew J Prendergast, Jean H Humphrey, Melissa J Gladstone

“…Functional difficulty score correlated negatively with MDAT: for each unit increase in WGCFM score, children completed 2.6 (95%CI: 2.2, 3.1) fewer MDAT items (p = 0.001). …”
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The effects of tobacco smoking on cognitive function and hematological parameters: a comparative cross-sectional study by Mahmood Abdalmonem Mohammed, Izzut Awad Ahmed, Hussam Mohammed Hassan, Muaath Ahmed Mohammed, Ibrahim Abdelrhim Ali

“…Background There is evidence that tobacco smoking negatively impacts mental and physical health. This study aimed to determine how tobacco smoking affects hemoglobin and cognitive functions of male smokers in Sudan.Methods This comparative - study involved 120 smokers and nonsmokers adult male participants. …”
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Relationship Between Socioeconomic Status and Depression in Older Adults: The Roles of Cognitive Function and Sleep Quality by Zheng Y, Zhang Y, Ye M, Qian Z, Zheng G

“…Mediating and moderating effects were analyzed using R 4.2.2 and SPSS 25.0 software.Results: The results showed that SES was negatively associated with depressive symptoms (β=− 0.234, p&lt; 0.001) and positively associated with cognitive function (β=0.566, p&lt; 0.001) after controlling for covariates; cognitive function played a partial mediating role between SES and depressive symptoms, and the indirect effect was β=− 0.09 (95% CI: − 0.129~ − 0.06, p&lt; 0.001), accounting for 38.5% of the total effect; and sleep quality positively moderated the mediating effect of cognitive function on relationship between SES and depressive symptoms (βsleep ×cognition =− 0.015, p&lt; 0.05).Conclusion: Depressive symptoms in community-dwelling older adults are affected by their SES and cognitive function. …”
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I Got Rhythm and Executive Function, Memory, and More: The Automated Test of Embodied Cognition (ATEC) by Morris D. Bell, Yarani Gonzalez, Andrea J. Weinstein, David Ciosek, Yan Wang, Gihyun Yoon

“…At-risk participants were also administered standard measures of executive functioning (EF), verbal list-learning, story memory, visual memory, and pre-morbid IQ. …”
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Vascular Adaptations in Pregnancy: The Critical Role of Endothelial Function and Nitric Oxide in Maternal-Fetal Health by Hina Riaz, Urooj Bhatti, Keenjher Rani, Afsheen Abro, Rabia Uqaili, Rubina Ahmdani

“…Serum NO and ET-1 levels were measured, and endothelial function was assessed using flow-mediated dilation (FMD). …”
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Mucosal barrier function and microbial community of small intestines in sheep in response to dietary energy concentrations by X.L. Wang, J. Zhou, M.L. Lu, S.P. Zhao, W.J. Li, G.B. Quan, B. Xue

“…To determine the optimal dietary energy concentration for the intestinal health of sheep, we compared microbiota, barrier function, and mucosal immunity in the small intestine of sheep consuming diets with different metabolisable energy (ME) concentrations. …”
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Intestinal inflammation and microbiota modulation impact cochlear function: emerging insights in gut-ear axis by Anna Pisani, Valentina Petito, Fabiola Paciello, Valeria Emoli, Letizia Masi, Veronica Mohamed Hizam, Pierluigi Puca, Raffaele Montuoro, Federica Del Chierico, Lorenza Putignani, Claudio Grassi, Jacopo Galli, Maurizio Taglialatela, Maria Emiliana Caristo, Gianluca Ianiro, Loris Riccardo Lopetuso, Giovanni Cammarota, Antonio Gasbarrini, Anna Rita Fetoni, Franco Scaldaferri

“…Notably, these effects were exacerbated by FMT from subjects with aUC, while FMT from patients with rUC provided a protective effect on cochlear functions. Conclusions Overall, our findings suggest that gut inflammation, microbiota alteration, or its therapeutic modulation can impact inner ear pathology: worsening gut inflammatory status negatively affects hearing sensitivity, while the restoration of gut microbiota positively impacts auditory function.…”
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Association of cystatin C with changes of left ventricular structure and function in individuals with different cardiovascular risk by I. Т. Murkamilov, V. V. Fomin, I. S. Sabirov, F. A. Yusupov

“…This study aims to investigate the association of cystatin C with changes of left ventricular structure and function in individuals with different cardiovascular risk (CVR).Material and methods. 267 patients with low-moderate (group I, n=58), high (group II, n=80) and extremely high (group III, n=129) CVR were examined. …”
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Esketamine modulates cerebral function variations between S1 and BLA in rats with chronic pain and anxiety by Yuanyuan Fang, Xiaokai Sui, Danhao Zheng, Jiahui Sun, Ting Chen, Junke Jia, Jing Yao, Jie Wang, Chang Chen, Zongze Zhang

“…Additionally, SNI rats showed an increased 13C enrichment of Glx3 in the cerebral cortex, striatum and thalamus, while esketamine reduced Glx3 enrichment in the cerebral cortex, indicating decreased cortical glutamate dynamics. Esketamine negated the increased functional connectivity between the right primary somatosensory cortex (S1R) and the basolateral amygdala (BLA) induced by chronic pain and anxiety. …”
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Serum extracellular matrix biomarkers in rheumatoid arthritis, psoriatic arthritis and psoriasis and their association with hand function by Helena Port, Birte Coppers, Sonja Tragl, Eva Manger, Lisa M. Niemiec, Sara Bayat, David Simon, Filippo Fagni, Giulia Corte, Anne-Christine Bay-Jensen, Koray Tascilar, Axel J. Hueber, Katja G. Schmidt, Verena Schönau, Michael Sticherling, Simon Heinrich, Sigrid Leyendecker, Daniela Bohr, Georg Schett, Arnd Kleyer, Signe Holm Nielsen, Anna-Maria Liphardt

“…PsO presented with higher levels of C1M compared to controls and to RA (p < 0.001 and p < 0.0001). PRO-C6 correlated negatively with MHQ (ρ = -0.39, p < 0.01) and grip strength (ρ = -0.31, p < 0.05) in PsO, while only weak correlations were observed between biomarkers and hand function scores for RA and PsA patients (all ρ <  ± 0.2–0.3). …”
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