A network toxicology approach to decipher paraben-induced molecular dysregulation in breast cancer pathogenesis by Wen Zhang, Rui Xiang, Wang Gu, Qiang Zhang, Lei Liu, Chenglin Wang, Muhu Chen, Yingchun Hu, Guihong Chen

“…Enrichment analysis demonstrated the molecular functions, biological processes involved, and related pathways of the intersection targets. …”
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Epileptic manifestations, cognitive impairment and autism spectrum disorders in patients with agenesis of the corpus callosum: the results of neuropsychological testing by O. A. Milovanova, O. A. Коmissarovа, T. Yu. Tarakanova, S. V. Bugry, G. G. Avakyan

“…In patients from Group I, the minimum value of the highest mental functions (HMF) score ranged from 25 to 51 (on average, Me =26.5) indicating severe cognitive disorders. …”
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The Molecular Mechanism by Which miR-211-5p Regulates the Proliferation and Differentiation of Preadipocytes in Meat Rabbits by Targeting TPK1 by Xiaoxiao Zhang, Meigui Wang, Tao Tang, Jing Zhou, Wenqiang Sun, Xianbo Jia, Jie Wang, Hengwei Yu, Songjia Lai

“…However, the precise functions of miR-211-5p in lipid deposition and lipogenesis in rabbit preadipocytes remain unclear. …”
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THE ANALYSIS OF THE PREVALENCE OF DENTAL ANOMALIES IN UZHHOROD SCHOOLCHILDREN by V.S. Melnyk, L.F. Horzov, O.Yu. Rivis, M.E. Izay

“…Anomalies in the size of the jaws (11.5%) and dentoalveolar anomalies of functional origin (4.1%) occur less often. However, 70.4% of all dentoalveolar anomalies are combined. …”
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Patient and Provider Perspectives of a Web-Based Intervention to Support Symptom Management After Radioactive Iodine Treatment for Differentiated Thyroid Cancer: Qualitative Study by Alaina L Carr, Angela M Jenkins, Jacqueline Jonklaas, Kate Gabriel, Kristen E Miller, Kristi D Graves

“…An additional aim included assessing features and functionalities desirable in the development of a web-based intervention to engage patients in their self-management and thyroid cancer survivorship care. …”
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Development of a Voice-Activated Virtual Assistant to Improve Insomnia Among Young Adult Cancer Survivors: Mixed Methods Feasibility and Acceptability Study by Hunter Groninger, Hannah Arem, Lylian Ayangma, Lisa Gong, Eric Zhou, Daniel Greenberg

“… BackgroundUp to 75% of young adult cancer survivors (YACS) experience chronic insomnia, negatively affecting physical and emotional health and overall quality of life. …”
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Behavior, hormone, and gut microbiota change by YYNS intervention in an OVX mouse model by Huajuan Lei, Huajuan Lei, Jian Liu, Juan Deng, Pan Zou, Zixiang Zou, Ziou Li, Honghui Li, Lin Luo, Zhoujin Tan

“…The relative abundance of the genus varied in each group. Moreover, functional correlation of changes in sex hormone and gut microbes between different groups showed that the PRL level was negatively correlated with Odoribacter. …”
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Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis by Wenfei Qin, Nuoming Yin, Binqiang Xu, Qixiang Mei, Yang Fu, Junjie Fan, Yingying Lu, Guangqiang Wang, Lianzhong Ai, Zhanjun Lu, Yue Zeng, Chunlan Huang

“…Results F. prausnitzii markedly ameliorated colitis by alleviating intestinal inflammation and barrier dysfunction, with significantly decreased abundance of pro-inflammatory taxa (Enterococcus, Desulfovibrio, Escherichia-Shigella, and Enterorhabdus) and increased abundance of Lachnospiraceae NK4A136_group. Functions related to intestinal immune network for IgA production pathway were up-regulated shown by transcriptomics and KEGG pathway analysis. …”
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Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…However, they can exacerbate disease outcomes in most bacteria and blood-borne viral conditions by impairing immune functions, such as neutrophil recruitment and antibody response, leading to more severe infections and higher viral loads. …”
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Bedrock geochemistry regulates glomalin-related soil protein accrual in subtropical karst forest soils, Southwest China by Qiumei Ling, Hanqing Wu, Qibo Huang, Yuan Zhao, Lei Xie, Qian Zhang, Wei Wan, Tiangang Tang, Peilei Hu, Dan Xiao, Jun Xiao, Ji Liu, Hu Du, Jie Zhao, Wei Zhang, Hongsong Chen, Kelin Wang

“…Structural equation modeling revealed that lithology-driven geochemical processes (e.g., rock weathering and mineral protection) indirectly regulated GRSP accrual via microbial functional traits. These findings shed light on the lithology-dependent regulation of GRSP dynamics and its pivotal roles in SOC sequestration, enhancing our capacity to predict and manage SOC storage within degraded karst forest ecosystems. …”
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A potent and broad CD4 binding site neutralizing antibody with strong ADCC activity from a Chinese HIV-1 elite neutralizer by Yingdan Wang, Ping Ji, Qianying Liu, Nannan Jia, Yunping Ma, Tianyi Yuan, Palizhati Rehati, Jiali Chen, Yumei Wen, Fan Wu, Jinghe Huang

“…The unique long CDRH3 loop of FD22 interacts with the CD4 binding site through its negatively charged residue R102, distinguishing it from other CD4bs antibodies. …”
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A consortium of seven commensal bacteria promotes gut microbiota recovery and strengthens ecological barrier against vancomycin-resistant enterococci by Alan Jan, Perrine Bayle, Nacer Mohellibi, Clara Lemoine, Frédéric Pepke, Fabienne Béguet-Crespel, Isabelle Jouanin, Marie Tremblay-Franco, Béatrice Laroche, Pascale Serror, Lionel Rigottier-Gois

“…Interestingly, five strains belong to species shared among humans and mice, and the other two have human functional equivalents. Conclusions An innovative approach based on mathematical modelling of the microbiota composition permitted to identify a mixture of commensal bacterial strains, which improves the ecological barrier effect against VRE. …”
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Comparative transcriptomics of atrazine-tolerant and sensitive alfalfa varieties under atrazine stress by Yingao Li, Chunyang Dong, Zeshan Zulfiqar, Haojie Wang, Jiading Lu, Xiaoxia Zhang, Jun Li, Yinghua Shi, Chengzhang Wang, Xiaoyan Zhu, Hao Sun

“…However, atrazine, a widely used herbicide, negatively impacts the growth and yield of alfalfa due to its residual presence in the environment. …”
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Novel Patterns of Photosynthetic Activity Within Canopies of Poplar Stands with Different Densities by Taijin Zhang, Xiaoting Liu, Qinhui Zhang, Hui Xiao, Yunong Han, Zhenghua Xing, Fusen Wang, Xiyang Zhao

“…Under three planting densities, leaf traits were negatively correlated with Pn, Tr, WUE, and Gs, but positively correlated with Ci. (4) Conclusions: As the planting density decreased, the photosynthetic capacity of poplar gradually increased. …”
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Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study by Samuel Asamoah Sakyi, Maxwell Hubert Antwi, Linda Ahenkorah Fondjo, Edwin Ferguson Laing, Richard K. Dadzie Ephraim, Alexander Kwarteng, Benjamin Amoani, Seth Christopher Appiah, Bright Oppong Afranie, Stephen Opoku, Tonnies Abeku Buckman

“…Vitamin D is a steroid hormone important for the normal functioning of the body. It is produced through skin exposure to sunlight and from the diet. …”
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Gut microbiota, immune cell, colorectal cancer association mediators: a Mendelian randomization study by Yuegang Li, Meng Zhuang, Shiwen Mei, Gang Hu, Jinzhu Zhang, Wenlong Qiu, Xishan Wang, Jianqiang Tang

“…Methods The analysis used genome-wide association study (GWAS) data encompassing 207 microbial taxa and 205 functional pathways and data on 731 immune cell phenotypes. …”
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Profiling of rhizosphere-associated microbial communities in North Alabama soils infested with varied levels of reniform nematodes by Sowndarya Karapareddy, Varsha C. Anche, Sowjanya R. Tamatamu, Madhusudhana R. Janga, Kathy Lawrence, Leopold M. Nyochembeng, Antonette Todd, Lloyd T. Walker, Venkateswara R. Sripathi

“…Some rhizospheric microbes can affect negatively on plant parasitic nematodes (PPNs) thus hindering the ability of nematodes in parasitizing the plant roots. …”
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Human menstrual blood-derived stem cells secreted ECM1 directly interacts with LRP1α to ameliorate hepatic fibrosis through FoxO1 and mTOR signaling pathway by Yangxin Fang, Lin Chen, Yin Yuan, Sining Zhou, Jiamin Fu, Qi Zhang, Ning Zhang, Yuqi Huang, Yifei Li, Li Yuan, Lijun Chen, Charlie Xiang

“…Results MenSC-secreted ECM1 exhibits potential to ameliorate liver fibrosis by inactivating HSCs, improving liver functions, and reducing collagen deposition in both cellular and mouse model of the CCl4-induced liver fibrosis. …”
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A new strategy of molecular breeding for optimal heading date and grain yield in rice by modulating elite allelic combinations of Ghd7, Hd3a, RFT1 and Gn1a by Qingmei Su, Rongsheng Wang, Xiaomin Feng, Mengyue Zhao, Guanlin Zhu, Qing Wang, Fang Zhang, Shaoyang Lin, Yuhang Zhang, Li Zhu, Qian Qian, Fan Chen

“…Our results revealed that under long-day (LD) conditions, Hd3a acts prior to RFT1 to promote heading while negatively regulating plant height and grain number. …”
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Quantum <i>κ</i>-Entropy: A Quantum Computational Approach by Demosthenes Ellinas, Giorgio Kaniadakis

“…One determined by a non-negativity definite quantum channel, with Kraus-like operator sum representation and its extension to a unitary dilation via a qubit ancilla. …”
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