Showing 12,101 - 12,120 results of 12,169 for search 'Negative function', query time: 0.19s Refine Results
  1. 12101
  2. 12102

    Immune-related gene risk model establishment and role of key gene FUCA1 in malignant pleural mesothelioma by Lin Shi, Lin Shi, Lin Shi, Lin Shi, Dongqi Yuan, Dongqi Yuan, Dongqi Yuan, Fuyi Zhu, Yuchao He, Yuchao He, Ran Zuo, Ran Zuo, Liwei Chen, Liwei Chen, Yi Luo, Yi Luo, Yu Wang, Yu Wang, Dingzhi Huang, Dingzhi Huang, Peng Chen, Peng Chen, Hua Guo, Hua Guo

    Published 2025-05-01
    “…Finally, the biological functions of the key gene were examined by in vitro and in vivo experiments.ResultsThe score model was used to divide patients with MPM into low- and high-risk groups. …”
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  3. 12103

    Novel artificial tricalcium phosphate and magnesium composite graft facilitates angiogenesis in bone healing by Yuan-Hsin Tsai, Chun-Chieh Tseng, Yun-Chan Lin, Howida M. Nail, Kuan-Yu Chiu, Yen-Hao Chang, Ming-Wei Chang, Feng-Huei Lin, Hui-Min David Wang

    Published 2025-04-01
    “…Furthermore, magnesium deficiency has been shown to negatively affect localized angiogenesis and bone repair. …”
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  4. 12104

    Depressive syndrome, cognitive impairment, and associated factors among community-dwelling aged persons in Cameroon by Gustave Mabiama, Dieudonné Adiogo, Pierre Marie Preux, Jean-Claude Desport, Philippe Fayemendy, Pierre Jésus

    Published 2024-12-01
    “…The Rosow Mobility Scale, Activities of Daily Living (ADL), and Instrumental Activities of Daily Living (IADL) scales were used to evaluate functional abilities. Chi-2, ANOVA, and multiple regression analyses were performed to assess the factors associated with DS and CI. …”
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  5. 12105

    Effect of black soldier fly (Hermetia illucens) larvae meal and oil on the performance, biochemical profile, intestinal health and gut microbial dynamics in laying hens by Samiullah Khan, Xiaoli Shi, Renlian Cai, Zhao Shuai, Wei Mao, Ibrar Muhammad Khan, Ayman A. Swelum, Jianjun Guo

    Published 2024-12-01
    “…The bacteria genera Ruminococcus, Clostridiales, Bacteroidales, Ruminococcus torques, and Intestinimonas were positively associated with the dietary treatments, while Prevotellaceae UCG-001, Clostridium, and Faecalibacterium were negatively associated with the dietary treatments. The inclusion of BSF meal and oil enriched the functional network of several pathways, including ascorbate and aldarate metabolism, D-arginine and D-ornithine metabolism, and fatty acid metabolism, highlighting the positive effects of BSF larvae meal and oil on the chicken gut microbiota. …”
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  6. 12106

    Screening potential diagnostic biomarkers for PLA2R‑associated idiopathic membranous nephropathy by WGCNA analysis and LASSO algorithm by Jinxu Huang, Yaqing Huang, Xiaoling Zeng, Yuhong Zhang, Junneng Zhang, Qingchu Hong, Yongtiao Peng

    Published 2025-12-01
    “…Functional studies, prompted by RASD1 downregulation, revealed enhanced cell activity and reduced apoptosis upon RASD1 overexpression compared to the Serum + Ov-NC control. …”
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  7. 12107

    Illuminating the dynamic water–nitrogen relationship in rice via stable isotope techniques to improve cultivation by Linlin Jiang, Bin Yang, Fan Zhao, Jie Pan, Zhenjie Chen, Junen Wu

    Published 2025-02-01
    “…N application generally increased yield, but excessive N negatively affected yield, especially in high-efficiency varieties. …”
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  8. 12108
  9. 12109

    Health-related quality of life in rare bleeding disorders: results from the Rare Bleeding Disorders in the Netherlands study by Sterre P.E. Willems, Marjon H. Cnossen, Nick van Es, Paul L. den Exter, Ilmar C. Kruis, Karina Meijer, Laurens Nieuwenhuizen, Joline L. Saes, Nicole M.A. Blijlevens, Waander L. van Heerde, Saskia E.M. Schols

    Published 2025-07-01
    “…ISTH-BAT scores were negatively associated with physical functioning. Conclusions: Overall HRQoL in patients with RBDs was comparable to the Dutch reference population. …”
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  10. 12110

    Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer by Jian Xu, Biao Yang, Ling Cheng, Chen Gan, Runze Huang, Anlong Li, Han Ge, Longyu Hu, Meiwen Ling, Xinyi Zheng, Bao Zhao, Mingjun Zhang, Huaidong Cheng, Huaidong Cheng

    Published 2025-07-01
    “…Functional enrichment implicated OSR1 in pathways related to peptide hormone secretion, peptide transport, metal ion response, and forebrain development. …”
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  11. 12111
  12. 12112

    Nutrient, Organic Matter and Shading Alter Planktonic Structure and Density of a Tropical Lake by Marina Isabela Bessa da Silva, Luciana Pena Mello Brandão, Ludmila Silva Brighenti, Peter A. U. Staehr, Cristiane Freitas de Azevedo Barros, Francisco Antônio Rodrigues Barbosa, José Fernandes Bezerra-Neto

    Published 2025-04-01
    “…Zooplankton presented a group dominance substitution in all mesocosms from copepod to rotifer species, and copepod growth seemed to be negatively affected by <i>Chlorella</i> sp. density increase. …”
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  13. 12113

    Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota by Lingyu Ruan, Zhennan Wang, Mengyun Zheng, Qi Zheng, Qing Qing, Hongyan Lin, Yuheng Tao, Liqun Wang, Junsong Wang, Wenhao Ge, Wenhao Ge

    Published 2025-05-01
    “…Further, 1H NMR based metabolomics and 16S rRNA gene sequencing examined gut microbiota metabolites and profiles, respectively, in order to elucidate the underlying mechanisms from the perspective of the gut-brain axis.ResultsPMP significantly improved the neurologic functions and reduced the cerebral infarction volume in MCAO/R rats. …”
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  14. 12114

    Fatty acid metabolism of granulose cells and follicular fluid and their associations with embryo quality in normal-weight women with PCOS by Ye Tian, Aiyuan Wang, Fang Li, Siyu Wang, Jie Shang, Kai Zhang, Xiaohong Bai

    Published 2025-06-01
    “…Results Proteomic analysis in cohort 1 revealed 205 differentially expressed proteins in the granulosa cells of normal-weight PCOS patients compared with those of controls. Functional enrichment analysis and metabolism score calculation revealed that fatty acid metabolism pathways, especially the biosynthesis of unsaturated fatty acids, were downregulated. …”
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  15. 12115

    Integrated microbiology and metabolomics analysis reveal the fermentation process and the flavor development in cigar tobacco leaf by Guanghai Zhang, Yue He, Wanlong Yang, Ziyi Liu, Zhonglong Lin, Tikun Zhang, Xiaohui He, Huachan Xia, Mengting Huo, Heng Yao, Gaokun Zhao, Yuping Wu, Guanghui Kong

    Published 2025-06-01
    “…Innovative discoveries of core functional microorganisms and key metabolites were made during fermentation, suggesting potential pathways for carbon and nitrogen metabolisms. …”
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  16. 12116

    The Role of CO<sub>2</sub> Levels in High-Oxygen Modified Atmosphere Packaging on Microbial Communities of Chilled Goat Meat During Storage and Their Relationship with Quality Attr... by Samart Sai-Ut, Sylvia Indriani, Nattanan Srisakultiew, Passakorn Kingwascharapong, Sarisa Suriyarak, Utthapon Issara, Suphat Phongthai, Saroat Rawdkuen, Jaksuma Pongsetkul

    Published 2025-05-01
    “…Interestingly, metagenomic functional profiling revealed that elevated CO<sub>2</sub> levels (>30%) altered metabolic pathways, shifting spoilage mechanisms from protein degradation in AP to carbohydrate metabolism in MAP, potentially influencing odor and texture attributes. …”
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    Article
  17. 12117

    Falls, Sleep Disorders and Cognitive Frailty in Hospitalized Older Adults with Hypertension:A Cross-Sectional Study by Li X, Li H, Gan S, Zhang Y, Yin D, Zhu B, Wang S, Liu Y

    Published 2025-06-01
    “…Xiaoyan Li,1 Huizhen Li,2 Shibao Gan,3 Youran Zhang,1 Dianhe Yin,1 Baihui Zhu,1 Shiyi Wang,1 Yuru Liu1 1Department of Geriatrics, Huaihe Hospital of Henan University, Kaifeng, Henan Province, People’s Republic of China; 2Department of Pulmonary Medicine, Kaifeng People’s Hospital, Kaifeng, Henan Province, People’s Republic of China; 3Department of Gastroenterology, Huaihe Hospital of Henan University, Kaifeng, Henan Province, People’s Republic of ChinaCorrespondence: Yuru Liu, Department of Geriatrics,Huaihe Hospital of Henan University, No. 115, Ximen Street, Longting District, Kaifeng, Henan Province, People’s Republic of China, Tel +86 136 9390 9362, Email liuyuru7979@163.comPurpose: Falls and fall-related injuries are highly prevalent among older adults. Falls negatively impact functional independence and quality of life, and are associated with increased morbidity, mortality, and healthcare costs. …”
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  18. 12118

    Single-cell transcriptome and multi-omics integration reveal ferroptosis-driven immune microenvironment remodeling in knee osteoarthritis by Yushun Wu, Jing Liu, Wenying Yu, Xiaoding Wang, Jian Li, Weiquan Zeng

    Published 2025-06-01
    “…Immune profiling showed reduced resting mast cells (p = 0.003) and monocytes (p = 0.02), with ABCC10 correlating negatively with CD8+ T cells (r = -0.65) and M1 macrophages. …”
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  19. 12119

    Shift work schedules alter immune cell regulation and accelerate cognitive impairment during aging by Karienn A. de Souza, Morgan Jackson, Justin Chen, Jocelin Reyes, Judy Muayad, Emma Tran, William Jackson, M. Karen Newell-Rogers, David J. Earnest

    Published 2025-01-01
    “…In shifted LD mice, the expansion in splenic B cells was negatively correlated with cognitive performance; when B cell numbers were higher, performance was worse in the Barnes maze. …”
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  20. 12120

    Nursing practice in relation to older people’s fundamentals of care in nursing homes: An exploratory design by O.M. Nordaunet, E.R. Gjevjon, H. Aagaard, C. Olsson, G. Borglin

    Published 2025-06-01
    “…We have highlighted the intricate nature of nursing practice, its relationship with clinical decision-making processes, and the functional and performance levels of nursing activities. …”
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