The association between eight complete blood count-derived inflammatory markers and muscle health by Jingyuan Zhang, Yuqi Wang, Heng Liu, Zhuolin Lei, Shouquan Cheng, Hong Cao

“…SII may be crucial in identifying “hidden sarcopenia” and the early stages of muscle functional decline.…”
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Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition by Jonathan M. Packer, Samantha G. Giammo, Lynde M. Wangler, Amara C. Davis, Chelsea E. Bray, Jonathan P. Godbout

“…Abstract Neuropsychiatric complications including depression and cognitive impairment develop, persist, and worsen in the years after traumatic brain injury (TBI), negatively affecting life and lifespan. Inflammatory responses mediated by microglia are associated with the transition from acute to chronic neuroinflammation after TBI. …”
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Evaluating the effectiveness and acceptability of two positive body image media micro-interventions among children aged 4–6 years old – a study protocol by H. G. Smith, K. M. Garbett, P. White, H. Williamson, N. Craddock

“…Abstract Background Children’s online media perpetuates appearance idealised images and can negatively impact the way children feel about their own and other people’s bodies (e.g., weight bias) at a young age. …”
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Exogenous proline enhances salt acclimation in soybean seedlings: Modifying physicochemical properties and controlling proline metabolism through the ornithine-glutamate dual pathw... by Lei Yan, Mu Lu, Muhammad Riaz, Kaiqing Tong, Hualong Yu, Guang Gao, Yusheng Niu

“…Soil salinization has emerged as a major factor negatively affecting soil quality and plant productivity. …”
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Family Resilience and Its Influencing Factors Among Patients With Lung Cancer Based on Double ABC‐X Theoretical Framework by Ziyi Shen, Yan Fang, Chengcheng Li, Xin Luo, Junling Cui, Yanchang Liu, Jingfang Hong

“…Clinically, interventions targeting these factors might significantly improve family functioning and coping mechanisms, contributing to better patient and family outcomes during cancer treatment and care.…”
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Nixtamalization and Extrusion Processes: Effects on Physicochemical, Nutritional, and Nutraceutical Properties in the Processing of Corn Into Tortilla by Ana Luisa Félix-Sámano, Jennifer Vianey Félix-Medina, María Fernanda Quintero-Soto, Ismael Diaz-Peña, Roberto Gutiérrez-Dorado

“…Mexico alone produces approximately 14.4 million cubic meters of nejayote daily, which negatively impacts the environment due to its highly alkaline pH (> 10). …”
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Soil and climate factors affect the nutrient resorption characteristics of desert shrub roots in Xinjiang, China by Yan Luo, Yan Luo, Yan Luo, Wenya Wei, Yaxuan Wang, Tianai Xue, Kaijuan Du

“…Climate factors exhibit distinct influences: AI shows positive correlations with PRE in C3 plants and with NRE in C4 plants. MAT negatively affects KRE in C4 plants, whereas MAP exerts a positive effect on it. …”
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A theory-based analysis of the implementation of online asynchronous telemedicine platforms into primary care practices using Normalisation Process Theory by Cara Leighton, Natalie Joseph-Williams, Annavittoria Porter, Adrian Edwards, Alison Cooper

“…Collective action was negatively affected by poor usability and integration of platforms into practice systems. …”
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A novel transcriptional regulator, CdeR, modulates the type III secretion system via c-di-GMP signaling in Dickeya dadantii by Alaleh Ghasemi, Xiaochen Yuan, Ching-Hong Yang

“…Although cyclic-di-GMP (c-di-GMP), a ubiquitous bacterial second messenger, negatively regulates the expression of T3SS genes in D. dadantii, the underlying mechanism remains unclear. …”
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Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women by Qiyuan Chang, Senlan Wang, Qingyun Mai, Canquan Zhou

“…Obesity, prevalent in 50–80% of PCOS patients, exacerbates metabolic disturbances and negatively influences assisted reproductive technology outcomes. …”
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Influence and Mechanism of Fertilization and Irrigation of Heavy Metal Accumulation in Salinized Soils by Dandan Yu, Qingfeng Miao, Haibin Shi, Zhuangzhuang Feng, Weiying Feng, Zhen Li, José Manuel Gonçalves

“…Specifically, Zn accumulation on the soil surface was primarily related to aliphatic organic functional groups, followed by soil salinity. Residual Zn in the crop grains was primarily associated with soil oxidation–reduction properties, followed by soil moisture content. …”
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Interrelation of dams sustainability with the local communities and water quality by A. Al-Afeshat, M.M. Zoubi, Q.Y. Abu Afifeh, H. Al-Jawaldeh, T.A. Qutishat, A.M.N. Masoud, M. Rahbeh

“…An average electrical conductivity of 1116 microsiemens per centimeter negatively affects dam sustainability and community engagement, highlighting water salinity's detrimental impact. …”
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Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression? by Martin Sebastian Winkler, Anne Rissiek, Marion Priefler, Edzard Schwedhelm, Linda Robbe, Antonia Bauer, Corinne Zahrte, Christian Zoellner, Stefan Kluge, Axel Nierhaus

“…The TNFα:HLA-DRA ratio correlated negatively with severity and the Sequential Organ Failure Assessment (SOFA) score (Spearman's rho -0.59, P<0.001).…”
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Single-Cell Sequencing and Machine Learning Integration to Identify Candidate Biomarkers in Psoriasis: INSIG1 by Zhou X, Ning J, Cai R, Liu J, Yang H, Bai Y

“…Finally, drug docking was performed on INSIG1, and the expression levels of INSIG1 in psoriasis were verified through clinical and in vivo experiments, and further in vivo experiments established the efficacy of tetrandrine in the treatment of psoriasis.Results: T cells were initially categorized into seven states, with differentially expressed genes in T cells (TDEGs) identified and their functions and signaling pathways. INSIG1 emerged as a characteristic gene for psoriasis and was found to be downregulated in psoriasis and potentially negatively associated with T cells, influencing psoriasis fatty acid metabolism, as inferred from enrichment and immunoinfiltration analyses. …”
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Danshenol B alleviates central post-stroke pain by regulating the PIK3CG/NLRP3 signaling pathway by Panyang Li, Linna Yu, Jinzhong Yao, Tingting Zhao, Sen Zhao

“…The overexpression of PIK3CG increased NLRP3 and negated the effects of Danshenol B, whereas its knockdown alleviated CPSP and reduced NLRP3. …”
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Preparation and Characterization of Al₂O₃/h-BN Composite Coatings by Atmospheric Plasma Spraying (APS) by Yifeng Guo, Lingxiao Lan, Boying Qin, Xinghua Liang, Yujiang Wang, Yu Wang, Zhikun Chen

“…To improve the adhesion strength of polymer functional films, corona treatment is required. Corona rollers are key components for corona treatment, which are used in high-voltage electric fields for a long time. …”
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Suppression of pseudogene MT2P1 transcription induced by E2F7 inhibits hepatocellular carcinoma cell proliferation and facilitates apoptosis via preserving its parental gene by Yiquan Lu, Yifan Zhang, Fengjie Hao, Nan Wang, Yongjun Chen, Junqing Wang

“…Their transcripts are mostly attributed to non-coding RNAs that play various functions in human tumorigenicity and progression. …”
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Increasing the efficiency of osseointegration in dental implantation in patients with diabetic osteopathy by remodeling bone tissue and intensifying its density. by O.O. Gudarian, D.O. Cherednyk

“…Our research and received data from laboratory studies showed that in patients with rapidly progressing generalized periodontitis with and without diabetic osteopathy, there is an inhomogeneity and imbalance in the functioning of bone remodeling, which negatively affects the process of osseointegration of dental implants and requires a complex approach in the selection of antiresorptive therapy. …”
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Identification of progression-related genes and construction of prognostic model for chronic kidney disease by machine learning by Bingkun Zhou, Hu Zhou, Xiaodong Huang, Shijie Liu

“…And the reliability of human CKD transcriptomic analysis and the feasibility of functional studies were validated in a mouse UUO model.ResultsCombining WGCNA and differential gene analysis, 9 genes positively associated with CKD occurrence and development and 20 genes negatively associated with that were identified. …”
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Humic substance application improves haematological indices of dog’s patients with myxomatous mitral valve disease by V. V. Rimskyi, V. S. Nedzvetsky

“…In the future, it is planned to study the effect of humic substances on the antioxidant/prooxidant balance of the dog, as well as to study their expected protective potential on the functioning of internal organs affected with myxomatous degeneration of the mitral valve.…”
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