Prevalence of insomnia, fatigue and symptoms of mental health problems among emergency medical service nurses: a cross-sectional study by Marieke M.E. Oosterhuis-Nienhaus, Lilian C.M. Vloet, Sarah I. Detaille, Hester Vermeulen, Jan Hoefnagel, Mischa Knol, Ellen Schepens, Mark van den Boogaard, Sivera A. A. Berben, Remco H. A. Ebben

“…Abstract Background Emergency medical service nurses worldwide face continuous high-stress situations caused by critical incidents that can overwhelm them emotionally and affect their daily functioning and sustainable employability. Repeated exposure to these incidents negatively impacts their mental health. …”
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Mitigation of Salt Stress in <i>Lactuca sativa</i> L. var. Gentile Rossa Using Microalgae as Priming Agents by Ornella Francioso, Michela Schiavon, Serenella Nardi, Davide Castellani, Erika Ferrari, Maria Teresa Rodriguez Estrada, Maria Cristina della Lucia, Veronica Zuffi, Andrea Ertani

“…Saline soils, characterized by elevated sodium chloride (NaCl) levels, negatively impact many crops, resulting in low productivity and high remediation costs. …”
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TOM40 as a prognostic oncogene for oral squamous cell carcinoma prognosis by Lifei Deng, Hong Ran, Dunhui Yang, Zhen Wang, Peng Zhao, Hengjie Huang, Yongjin Wu, Peng Zhang

“…A network of genes co-expressed with TOM40 was constructed and functionally annotated by gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses. …”
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Clinical features evaluation of myopic fundus tessellation from OCTA and MfERG by Yanyan Zhang, Yan Zhong, Wei Mao, Zhe Zhang, Yusheng Zhou, Hu Li, Jianing Ying, Quanyong Yi

“…Translational relevance: Assessment in fundus tessellation morphologically and functionally using MfERG and OCTA contributes to classification and clinical prediction of fundus tessellation.…”
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Physiological and transcriptomic-based analysis reveal the common and specific pathways of clove basil (Ocimum gratissimum) organs in response to cadmium stress by Bin Wang, Yanhui Xiao, Xiao Yuan, Yukun Wang, Dengyue Jiang, Zhaoxia Zhan, Jinming He

“…A total of 2,930, 594, and 2193 differentially expressed genes (DEGs) were identified in the roots, shoots, and leaves, respectively. Functional enrichment analysis revealed significant variations in the unique DEGs among each organ. …”
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Home-based self-administered transcranial direct current stimulation for women affected by primary dysmenorrhoea in Northeastern Brazil: a protocol study by Thiago Anderson Brito De Araújo, Edson Silva-Filho, Rodrigo Pegado, Tatiana Camila de Lima Alves da Silva, Yvinna Tamiris Rodrigues, Paloma Cristina Alves de Oliveira, Ervinas Bernatavicius, Alexander Anthony Cook, Emilè Radytè, Maria Thereza Micussi

“…Background The prevalence of women with primary dysmenorrhoea is high and negatively impacts physical and mental health. The intense cyclic episodes of pain generate central nervous system dysfunctional processing. …”
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Grip Strength, Fall Efficacy, and Balance Confidence as Associated Factors with Fall Risk in Middle-Aged and Older Adults Living in the Community by Priscila Marconcin, Estela São Martinho, Joana Serpa, Samuel Honório, Vânia Loureiro, Marcelo de Maio Nascimento, Fábio Flôres, Vanessa Santos

“…Background: Falls are a major public health concern among older adults, often resulting in injury, functional decline, and reduced quality of life. While handgrip strength (HGS), fall efficacy, and balance confidence have individually been associated with fall risk, their combined predictive value is still underexplored, particularly in physically active older adults. …”
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Multi-omics profiling of dairy cattle oxidative stress identifies hindgut-derived Phascolarctobacterium succinatutens exhibiting antioxidant activity by Duo Gao, Yimin Zhuang, Shuai Liu, Boyan Ma, Yiming Xu, Hongxing Zhang, Yiliyaer Nuermaimaiti, Tianyu Chen, Guobin Hou, Wenli Guo, Jingtao You, Zhiyu Huang, Jianxin Xiao, Wei Wang, Mengmeng Li, Shengli Li, Zhijun Cao

“…Using a multi-omics approach, we performed 16S rRNA gene sequencing to evaluate microbial diversity, conducted metagenomic analysis to identify functional bacteria, and utilized untargeted metabolomics to profile serum metabolites. …”
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miR-32-5p suppresses the progression of hepatocellular carcinoma by regulating the GSK3β/NF-κB signaling by Wang Guangzhi, Yang Qianqian, Han Yaqi, Zhang Yunlong, Pan Wei, Ma Zhongliang, Tian Hui, Qu Xudong

“…In this study, qRT-PCR is utilized to precisely determine the downregulated expression levels of miR-32-5p in HCC. Subsequently, functional analysis reveals the suppressive role of miR-32-5p in modulating the proliferative and migratory capabilities of HCC cells. …”
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Tomato leaves as a sustainable biosorbent for the effective removal of some organic dyes and lead from water by Layan Helmi, Suhair Sunoqrot, Akram Hijazi, Maria Alayli, Hiba N. Rajha, Maram Al Bakri, Mohammad H. El-Dakdouki, Nada El Darra

“…Industrial wastewater is a major source of pollution that continues to negatively impact ecosystems and human health. It contains contaminants such as dyes, heavy metals, pharmaceuticals, and pesticides, emphasizing the urgent need for effective water purification methods. …”
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Rapid diagnosis of rheumatoid arthritis and ankylosing spondylitis based on Fourier transform infrared spectroscopy and deep learning by Wei Shuai, Xue Wu, Chen Chen, Enguang Zuo, Xiaomei Chen, Zhengfang Li, Xiaoyi Lv, Lijun Wu, Cheng Chen

“…Objective: Rheumatoid arthritis and Ankylosing spondylitis are two common autoimmune inflammatory rheumatic diseases that negatively affect activities of daily living and can lead to structural and functional disability, reduced quality of life. …”
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Highly expressed of SERPINA3 indicated poor prognosis and involved in immune suppression in glioma by Qing Yuan, Song‐Quan Wang, Guang‐Tao Zhang, Jie He, Zhi‐Dan Liu, Ming‐Rong Wang, Hong‐Qing Cai, Jing‐Hai Wan

“…Methods We analyzed the biological functions of SERPINA3 through data from the Chinese Glioma Genome Atlas databases. …”
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Brain Structural Correlates of EEG Network Hyperexcitability, Symptom Severity, Attention, and Memory in Borderline Personality Disorder by Andrea Schlump, Bernd Feige, Swantje Matthies, Katharina von Zedtwitz, Isabelle Matteit, Thomas Lange, Kathrin Nickel, Katharina Domschke, Marco Reisert, Alexander Rau, Markus Heinrichs, Dominique Endres, Ludger Tebartz van Elst, Simon Maier

“…In particular, intermittent rhythmic delta and theta activity (IRDA/IRTA) has drawn attention in mental health contexts due to its links with metabolic imbalances, neuronal stress, and emotional dysregulation—processes that are highly pertinent to BPD. These functional disturbances may be reflected in corresponding structural brain changes. …”
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Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism by Dandan Yang, Dandan Yang, Wuyunsiqin, Wuyunsiqin, YanNiu, Hashentuya, Tana, Anna, Mingxing Ma, Wenhui Zhao, Menggenduxi, Minjie Wang, Minjie Wang

“…According to Spearman’s correlation coefficient analysis, up-regulation of Porphyromonadaceae, Prevotella, and Bacteroidota after MMQ-8 intervention was negatively correlated with LPC levels in glycerophospholipid metabolic pathways, while positively correlated with PC levels. …”
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Diagnostic Efficacy of Combined N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) and Cardiac Troponin I (cTnI) Testing in Myocardial Injury of Children with Mycoplasma Pneumoni... by Yang M, Xuan A, Zhu G

“…Patients were stratified by New York Heart Association (NYHA) functional class (I–IV). Demographic and clinical characteristics, biomarker levels, and diagnostic accuracy were analyzed. …”
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Understanding continued use of smart learning platforms: psychological wellbeing in an extended TAM-ISCM model by Jinlei Li, Meilin Jin, Xiaowei Chen, Xiaowei Chen

“…Interestingly, perceived trust negatively affected satisfaction (β = −0.13, p &lt; 0.05), possibly due to a mismatch between institutional trust and user expectations, which may lead to psychological strain. …”
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Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients by Zi-han Gou, Nan Su, Xiao-chuan Li, Da-peng Ren, Shan-shan Ren, Lin Wang, Yao Wang

“…The results indicated that POD is positively associated with pyroptosis and parthanatos, while negatively correlated with oxidative stress and disulfidptosis. …”
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An AI-Based Telerehabilitation Solution to Improve Mobility in People With Multiple Sclerosis (the PLATINUMS Project): Protocol for an Implementation and Evaluation Study by Lars Hvid, Susan Coote, Massimiliano Pau, Alon Kalron

“…WP3 comprises a validity study (n=60) to evaluate remote mobility tests via the system, such as the Short Physical Performance Battery (SPPB), functional reach, and sit-to-stand tests, to ensure their reliability for use in WP4, the feasibility multicenter randomized controlled trial (RCT). …”
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Health literacy interventions in adult speech and language therapy: A scoping review by Verna B. McKenna, Órla Gilheaney

“…Abstract Background Reduced health literacy can negatively impact care seeking, satisfaction with care and overall health outcomes. …”
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Has_circRNA_0122683 (circ-PRKCI) relieves ferroptosis of HPAEpiCs in sepsis-induced acute lung injury by sponging miR-382-5p by Limei Yan, Xiajun Lu, Ning Wang, Peng Jia

“…The area under the curve values of ROC curves for circ-PRKCI in differentiating septic ALI patients from healthy individuals and septic non-ALI patients were 0.996 and 0.999, respectively. Functional in vitro assays revealed that enforced expression of circ-PRKCI alleviated LPS-induced ferroptosis and inflammatory response of HPAEpiCs, which were reversed by Erastin or FIN56 administration. …”
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