Downstream testing after CT coronary angiography: time for a rethink? by Matthias Schmitt, Michelle Claire Williams, Ben Holloway, Gareth Morgan-Hughes, Alice Veitch, Robin Van Lingen, Nicholas Bellenger

“…For 552 (10%) CAD-RADS 4 and 91 (2%) CAD-RADS 5 patients, ICA revascularisation rates were 64% (221/345) and 74% (46/62), respectively.Conclusions While CTCA for recent-onset chest pain assessment has been shown to be a robust test, which negates the need for further investigation in three-quarters of patients, subsequent ICA overuse remains with almost half of these procedures not leading to revascularisation.…”
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Obstructive Sleep Apnea and Sleep Disorders in Children with Attention Deficit Hyperactivity Disorder by Mai Nguyen-Thi-Phuong, Mai Nguyen-Thi-Thanh, Robert Joel Goldberg, Hoa L. Nguyen, An Dao-Thi-Minh, Sy Duong-Quy

“…These disturbances can exacerbate ADHD symptoms and negatively affect cognitive, emotional, and behavioral functioning. …”
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Family hardiness among primary caregivers of breast cancer patients in Hunan Province: a cross-sectional study exploring the relationship with attachment and caregiver preparedness by Xin Sun, Lili Xu, Lijuan Sheng

“…BackgroundFamily hardiness is a key variable contributing to positive family functioning, which has significant effects on the quality of life and the mental health of patientsand caregivers. …”
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Elucidating the role of LGALS3BP in coronary atherosclerosis: integrating bioinformatics and machine learning for advanced insights by Suzhen Zhao, Chuanxin Zhao, Linlin Wang, Baoe Cheng, Man Zheng, Xiuyun Wang

“…Results Among the 10 DEGs associated with LGALS3BP, 13 hub genes were identified via LASSO and SVM-RFE analyses. Functional assays highlighted LGALS3BP’s involvement in viral defense, cytokine production, and immune cascades. …”
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Expression patterns of protein kinases correlate with gene architecture and evolutionary rates. by Aleksey Y Ogurtsov, Leonardo Mariño-Ramírez, Gibbes R Johnson, David Landsman, Svetlana A Shabalina, Nikolay A Spiridonov

“…Breadth of PK expression negatively correlates with rate of non-synonymous substitutions in protein coding regions. …”
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SPDL1 overexpression was associated with poor prognosis and immune status in HCC through in vitro experiment and bioinformatics analysis by Ying-Ming Xu, Bo-Hua You, Ming Chen, Tian-Ping Xiong, Lin Shi, Qin Wei, Zhong-An Wang

“…Bioinformatics and in vitro approaches were employed to investigate the biological functions, signaling pathways, and protein networks involving SPDL1. …”
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PENGARUH MEKANISME GOOD CORPORATE GOVERNANCE TERHADAP KINERJA KEUANGAN SELAMA KRISIS KEUANGAN TAHUN 2007-2009 by Purweni Widhianningrum, Nik Amah

“…It is used to meet the regulation only so that supervisory functions that should be the responsibility of commissioners is ineffective. …”
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Investigation of the amino acid composition of gluten-free biscuit with carob by S. S. Zyuzina, M. D. Shchelkova, Yu. V. Ushakova, G. E. Rysmukhambetova

“…In addition, an unbalanced amino acid composition can cause an imbalance in the human body and negatively affect the functioning of muscles, heart, brain and other organs, leading to diseases. …”
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Regional cerebral hypoperfusion as a cause of symptoms and progression of multiple sclerosis by L. N. Prakhova, A. G. Ilves, Z. I. Savintseva, N. M. Kuznetsova, K. S Rubanik, G. V. Kataeva

“…The patients underwent contrast-enhanced MR perfusion of the brain on the 3 Tesla MR-tomograph, as well as the Functional System Score, Expanded Disability Status Score and Fatigue Status Score evaluation. …”
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The Value of Community Capitals in Sustainable Urban Development: A Qualitative Exploration of Urban Informal Workers by Ivy Chumo, Blessing Mberu, Caroline Kabaria

“…Urban informality, often viewed negatively, is not solely the product of the urban poor but also reflects the failure of formal systems to adapt. …”
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Genome-wide identification and analysis of the FLA gene family in maize (Zea mays L.) and its expression in response to abiotic stresses by Yongyan Cao, Xuanxuan Chen, Bo Wei, Tuo Zeng, Hongcheng Wang, Bin Zhu, Xuye Du, Lei Gu

“…Conclusion Taken together, the comprehensive analysis of ZmFLAs in the whole genome provides a novel perspective on the evolutionary relationship among maize FLA genes and lays a foundation for further analysis of the biological functions of ZmFLAs.…”
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Comprehensive Analysis of lncRNA Expression Profile and the Potential Role of ENST00000604491 in Graves’ Disease by Yingzhao Liu, Junli Zou, Juan Xu, Xuehua Wang, Jie Xing, Li Wang, Huiyong Peng

“…Long noncoding RNAs (lncRNAs) are widely expressed in multiple human diseases and have pivotal functions in gene regulation. This study is aimed at determining the lncRNA profile in peripheral blood mononuclear cells (PBMCs) from GD patients and investigating the role of ENST00000604491 in GD. …”
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Feature-based enhanced boosting algorithm for depression detection by Muhammad Sadiq Rohei, Kasturi Dewi Varathan, Shivakumara Palaiahnakote, Nor Badrul Anuar

“…Depression is a rapidly increasing mental disorder that can interfere with a person’s ability and negatively affect functions in various aspects of life. …”
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The Effects of Iron-Bearing Minerals on the Community Diversity and Physiological Activity of Prokaryotic Microorganisms in Pit Mud Used for Strong-Flavor <i>baijiu</i> Production by Kairui Jiao, Bo Deng, Ping Song, Liwei Wang, Bin Lian

“…TFe and Fe_c were significantly negatively correlated with both the Chao1 and Shannon indexes and functional microorganisms such as <i>Clostridium_sensu_stricto_12</i>, <i>Sedimentibacter</i>, and hydrogenotrophic methanogens. …”
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Analgesic effect of simultaneously targeting multiple pain processing brain circuits in an aged humanized mouse model of chronic pain by transcranial focused ultrasound by Min Gon Kim, Chih-Yu Yeh, Kai Yu, Zherui Li, Kalpna Gupta, Bin He

“…In addition to its efficacy, our behavioral-based safety assessment revealed no adverse effects on motor functions. These results suggest that using a battery-powered, compact UAFE to simultaneously target multiple pain-processing circuits can effectively suppress heat pain-related behaviors in aged female sickle mice without negatively impacting motor coordination and balance. …”
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Improving beef burger quality during cold storage: effect of Aloe vera gel, packaging, and temperature by Betina Louise Angioletti, Tuany Gabriela Hoffmann, Stefany Pergentino dos Santos, Caroline Meinert, Sávio Leandro Bertoli, Elane Schwinden Prudêncio, Carolina Krebs de Souza

“…Abstract Lipids, one of the main macronutrients in beef burgers, can undergo oxidative reactions, negatively affecting product quality. Recently, Aloe vera (Aloe barbadensis Miller), a natural antioxidant, has gained attention as a functional food ingredient in the food industry due to its potential to promote food preservation and human health. …”
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RETRACTED ARTICLE: Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells by Hengshan Zhu, Chuang Lou, Ping Liu

“…However, the expression pattern and functional role of IL-27 in viral myocarditis (VMC) has not been investigated. …”
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A qualitative study on the impact of bleeding disorders on the daily life of Dutch women by Tessa C. M. van Gastel, Lorynn Teela, Manon E. L. Degenaar-Dujardin, Vicky Lehmann, Marjolein Peters, Karin Fijnvandraat, Lotte Haverman

“…Focus groups or semi-structured interviews about the themes (1) healthcare, (2) social functioning, (3) work and education, and (4) sexuality and intimacy were conducted in person or online, based on women’s preference. …”
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The value and application of a poorly differentiated cluster-based Ezrin marginal score system in the prognostic assessment of colorectal cancer by Yangyang Jiang, Ling Liu, Yingying Chang, Limei Gu, Yaohui Wang, Ting-Sheng Ling, Xiaolong Zhang

“…Conclusion The innovative PDC-EMS scoring system developed in this study demonstrates functional consistency with both PDC grading and TB grading. …”
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Assessing social cognition and risk-taking behaviour in patients with young-onset dementia: Study protocol for the YOD-RiSoCo observational prospective cohort study. by Floor Gelmers, Rients B Huitema, Myrthe E Scheenen, Barbara C van Munster, Jacoba M Spikman, YOD-INCLUDED Consortium

“…Furthermore, the study will contribute to a better identification of those social behavioural symptoms that negatively affect functioning and social relations.<h4>Trial registration</h4>The trial is registered at www.clinicaltrials.gov with identifier NCT06286293.…”
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