Development and quality evaluation of high-protein gluten-free pasta formulations by Sayed Mostafa, Shymaa M. Ata, Ahmed M. S. Hussein, Ahmed A. Zaky

“…The impacts of different formulations on pasting behavior and functional properties were assessed. The final products were evaluated for their physicochemical properties, hardness, phenolic content, protein digestibility, cooking quality, and sensory attributes. …”
Get full text

Impact of Shield Under-Passing on Existing Tunnel Settlement Considering Construction Factors by XUE Ziqian, XIA Hongchun, ZHU Xunguo, YAN Huajun

“…The settlement fitting curve functions of different soil chamber pressures and grouting pressures are capable to predict the settlement of the existing tunnel under the change of multiple construction factor levels. …”
Get full text

Research progress in effects of biochar on transport of inorganic pollutants in soil by ZHANG Dong, LIU Xingyuan, ZHAO Hongting

“…Biochar has been considered as a low-cost and high-efficiency sorbent for both organic and inorganic contaminants including heavy metals, radioactive elements, nitrogen and phosphate, due to its abundant O-containing functional groups and surface charges, advanced micro-and macro-pore structures, and rich carbon content.In this paper, recent research progress on biochar with regards to its mechanisms and potential applications in remediation of inorganic contaminated soils was reviewed. …”
Get full text

Integrative analysis of T cell-mediated tumor killing-related genes reveals KIF11 as a novel therapeutic target in esophageal squamous cell carcinoma by Xinxin Cheng, Huihui Zhao, Zhangwang Li, Liping Yan, Qingjie Min, Qingnan Wu, Qimin Zhan

“…Moreover, we performed functional experiments on KIF11, which ranked as the most significant prognostic risk gene among the 8 TTK-related genes. …”
Get full text

ORGANIZING THE WORK OF THE DONOR BREAST MILK BANK AT THE LVIV PERINATAL CENTER IS AN EXPERIENCE THAT MOTIVATES FURTHER DEVELOPMENT by М. Малачинська, М. Кісельова, О. Шлемкевич, Н. Вереснюк, Г. Коваленко

“…Errors in feeding breastfed infants negatively affect not only the child’s physical health but also their functional capacities. …”
Get full text

Changes in the ocular surface condition during the transition to preservative-free hypotensive combination therapy in the long-term observation of patients with advanced stages of... by Dmitry A. Dorofeev, Aleksandr A. Vitkov, Elena V. Kirilik, Ksenia O. Lukyanova, Olga G. Pozdeeva

“…Most of the drugs used contain a preservative, which can negatively affect the condition of the ocular surface. …”
Get full text

Exploring Expectations Regarding Aging and Related Influencing Factors in Older People with Type 2 Diabetes Mellitus: A Cross-Sectional Study by Yao T, Jiang Q, Zhang F, Cao H, Li D, Yan J, Wang Y, Yang J, Zhuang R, Sun J

“…The level of ERA is negatively correlated with depression (r = − 0.549, p < 0.01) and positively correlated with social support (r = 0.625, p < 0.01) and diabetes self-efficacy (r = 0.514, p < 0.01). …”
Get full text

Features and Transformation Mechanism of Online and Offline Popularity in Digital Era Tourism of Ancient Towns: A Case Study of Lijiang Dayan Ancient Town by Chen Xiaokui, Mao Zhirui, Yi Chun, Gao Yujie

“…In the offline dimension, tourists' mobile behavior was positively affected by shopping service facilities, attractions, leisure and entertainment facilities, functional density, building density, and sDNA (spatial Design Network Analysis) proximity (r=400 m), and negatively affected by infrastructure, educational service facilities, and sDNA accessibility (r=n). …”
Get full text

Comparison between unimodal and multimodal Physical Therapy interventions in frailty: a systematic review by Maria Simões, Patrícia Moura, Marina Nascimento, Renata Varanda, José Pompeu

“…Studies analyzed the following clinical outcomes: mobility, muscle strength, balance, falls and fear of falling, quality of life and functional capacity. We conclude that both unimodal and multimodal interventions have potential to promote beneficial effects, but the analyzed studies have important methodological issues that negatively affect their quality. …”
Get full text

<i>DBI</i> as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL by Ting Tian, Huan Han, Jingtao Huang, Jun’e Ma, Ruoxi Ran

“…The remaining proteins demonstrated diverse and complex functions within the tumor immune microenvironment, providing novel insights for the development of precision diagnostics and immunotherapeutic strategies.…”
Get full text

Persistent Activation of Sphingosine‐1‐Phosphate Receptor 1 by Phytosphingosine‐3,4‐Cyclic Phosphate Ameliorates Sepsis by Inhibiting Hyperinflammation and Vascular Hyperpermeabili... by Suhong Duan, Seung‐Gook Kim, Jiaying Bao, Hyung‐Jin Lim, Joon Woo Kim, Sung‐Il Yoon, Young Jun Park, Sanguk Yun, Kye‐Seong Kim, Hwa‐Ryung Song, Myeong Jun Choi, Myung‐Kwan Han

“…Sphingosine‐1‐phosphate (S1P) levels are significantly lower in patients with sepsis and are negatively correlated with the severity of sepsis. However, whether the S1P signaling pathway is a target for sepsis treatment remains unknown. …”
Get full text

“Just sort of treading water”: Qualitative study of the lived experiences of romantic partners of diplomats by Samantha K. Brooks, Dipti Patel, Rachael Gribble, M. Brooke Rogers, Neil Greenberg

“…Most participants had given up their careers to accompany their partners overseas which appeared to negatively affect their sense of identity and they struggled to find work at overseas posts. …”
Get full text

MicroRNA-767-5p promotes metastasis but improves chemotherapeutic and radiotherapeutic sensitivity of osteosarcoma by Xuelian Luo, Xiaoyan Dai, Qingsong Wei, Xiaorong Tan, Shuai Wang, Hanxi Xiao, Xuan Yao, Youcai Deng, Zhaoyang Zhong

“…We observed that miR-767-5p expression in the specimens of patients with metastatic OS was higher than in healthy individuals and was also negatively correlated with the overall survival of patients with OS. …”
Get full text

The aftermath of trauma on resting state source-level MEG microstate dynamics by Massimo Bertoli, Pierpaolo Croce, Filippo Zappasodi, Rosalia Di Matteo, Federica Vellante, Mauro Pettorruso, Giovanni Martinotti, Marcella Brunetti

“…Background: Traumatic events can disrupt psychological functioning, leading to conditions such as post-traumatic stress disorder (PTSD). …”
Get full text

Characteristics and nutritional value of cookies fortified with debittered salmon (Salmo salar) frame protein hydrolysate by Kartik Sharma, Mallikarjun Chanchi Prashanthkumar, Umesh Patil, Lukai Ma, Soottawat Benjakul

“…The rising demand for nutrient-enriched snacks presents an opportunity to develop functional foods to tackle malnutrition problems. This study aimed to enhance the nutritional value of cookies by incorporating debittered salmon frame-protein hydrolysate (DSF-PH), prepared via Maillard reaction between protein hydrolysate and glucosamine. …”
Get full text

Effects of Omega-3-Rich Pork Lard on Serum Lipid Profile and Gut Microbiome in C57BL/6NJ Mice by Anantawat Koontanatechanon, Manoosak Wongphatcharachai, Nutthawan Nonthabenjawan, Pichaya Jariyahatthakij, Thanchanok Khorporn, Wanpeuch Parnsen, Benjawan Keattisin, Pattarin Leksrisompong, Pairat Srichana, Sattrachai Prasopdee, Sittiruk Roytrakul, Kusuma Sriyakul, Veerachai Thitapakorn, Kammal Kumar Pawa

“…It could also be introduced as a functional ingredient for patients with hyperlipidemia.…”
Get full text

The immune-related gene CD5 is a prognostic biomarker associated with the tumor microenvironment of breast cancer by Yi Zhao, Hengheng Zhang, Wenwen Wang, Guoshuang Shen, Miaozhou Wang, Zhen Liu, Jiuda Zhao, Jinming Li

“…The tumor microenvironment (TME) plays an important role in this process, but the functions of immune components and stromal components in the TME require further elucidation. …”
Get full text

Comprehensive Ubiquitome Analysis of <i>Nicotiana benthamiana</i> Leaves Infected with Tomato Brown Rugose Fruit Virus by Jiali Yang, Donghai Wang, Boshen Zhang, Mangle Chen, Jianping Chen, Fei Yan, Shaofei Rao

“…Furthermore, enrichment analysis indicated that ToBRFV infection induces an increase in the ubiquitination levels of proteins associated with ion transport, MAPK signaling pathways, and plant hormone signal transduction, while the ubiquitination levels of proteins related to carbon metabolism and secondary metabolite synthesis decreased. Functional analysis of the three differentially ubiquitinated proteins revealed that a RING/U-box superfamily protein negatively regulates ToBRFV infection. …”
Get full text

Genome-wide association study identifies candidate genes for bacterial soft rot resistance in cucumber seedlings by Yi Zhang, Shaoyun Dong, Jiantao Guan, Xiaoping Liu, Xuewen Xie, Karin Albornoz, Jianan Han, Zaizhan Wang, Xingfang Gu, Shengping Zhang, Han Miao

“…Based on haplotype analysis, sequence polymorphisms, functional annotation and qRT-PCR analysis, six candidate genes were identified within the five loci. …”
Get full text

Proinflammatory follicular helper T cells promote immunoglobulin G secretion, suppress regulatory B cell development, and correlate with worse clinical outcomes in gastric cancer by Hong Zhang, Rongxi Yue, Pengfei Zhao, Xuetao Yu, Junguo Li, Guoqing Ma, Jiahong Tang, Lixin Zhang, Liying Feng, Lidong Sun, Zongchang Song, Chunliang Guo, Ning Wang

“…In this study, we investigated the potential involvement of follicular helper T cells in gastric cancer. Functions of follicular helper T subsets were examined in Helicobacter pylori –infected gastric cancer patients and H. pylori –infected but asymptomatic individuals. …”
Get full text