Safety and usability of oncology information systems – a systematic review by Nikola Cihoric, Elena Riggenbach, Paul Martin Putora, Fabio Dennstädt

“…However, some reports point to severe problems regarding usability, which negatively impact the clinical workforce, as well as safety issues related to electronic health records, which potentially endanger patients. …”
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Long noncoding RNA HOXB13‐AS1 regulates HOXB13 gene methylation by interacting with EZH2 in glioma by Yu Xiong, Wei Kuang, Shigang Lu, Hua Guo, Miaojing Wu, Minhua Ye, Lei Wu

“…Functional experiments in vitro and in vivo revealed that high level of HOXB13‐AS1 increased cell proliferation and tumor growth by promoting cell cycle progression. …”
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Effect of Steel Fiber on First-Cracking Behavior of Ultra-High-Performance Concrete: New Insights from Digital Image Correlation Analysis by Xing Lu, Lei Tu, Chengjun Tan, Hua Zhao

“…The first-cracking behavior of ultra-high-performance concrete (UHPC) is critical for the functionality and durability of its structures. However, determining the first-cracking strength by the linear limit point is challenging due to the nonlinear behavior before the initial crack. …”
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Communication challenges and experiences between parents and providers in South Korean paediatric emergency departments: a qualitative study to define AI-assisted communication age... by Meong Hi Son, Sejin Heo, Sohyeong Jeong, Hansol Paeng, Suyoung Yoo

“…Objectives This study aimed to explore communication challenges between parents and healthcare providers in paediatric emergency departments (EDs) and to define the roles and functions of an artificial intelligence (AI)-assisted communication agent that could bridge existing gaps.Design A qualitative study using in-depth interviews and affinity diagram methodology to analyse interview data.Setting A tertiary paediatric ED in South Korea.Participants 11 parents of paediatric patients and 11 ED staff members (physicians, nurses and security personnel).Primary and secondary outcome measures The study examined parent–provider communication difficulties, emotional responses and situational factors contributing to miscommunication and increased workload for ED staff.Results The study identified key emotional factors—fear, anger and sadness—that negatively affect communication between parents and ED staff. …”
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Can dextromethorphan-bupropion reduce mental pain in depressed individuals? A hypothesis-generating overview perspective by Maurizio Pompili, Isabella Berardelli, Denise Erbuto, Filippo Caraci

“…Abstract Globally, major depressive disorder, or MDD, is a leading cause of disability. It negatively impacts social interactions and significantly limits daily functioning, ultimately reducing life satisfaction. …”
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Dopaminergic Modulation of Medial Prefrontal Cortex Deactivation in Parkinson Depression by Anders H. Andersen, Charles D. Smith, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Frederick A. Schmitt, Lee X. Blonder

“…Patients viewed photographs of emotional faces during functional MRI. Scans were performed while the patient was taking anti-Parkinson medication and the day after medication had been temporarily discontinued. …”
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Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson’s Disease by Nadeeka N. W. Dissanayaka, Farah Idu Jion, Nancy A. Pachana, John D. O’Sullivan, Rodney Marsh, Gerard J. Byrne, Paul Harnett

“…Motor and nonmotor symptoms negatively influence Parkinson’s disease (PD) patients’ quality of life. …”
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Modeling Intra-Organization Fragmentation and Integration to Enhance Performance in Industrialized Timber Construction by Harrison Mesa, Macarena Ramírez, Pablo Guindos, Manuel Carpio

“…The VDT’s baseline results reveal significant rework from inadequate early integration among specialties and functional departments, increasing the project schedule. …”
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PIEZO1 activity promotes stemness in mesenchymal stem cells under shear stress and enhances protection of leukemia cells by Amit Sharma, Jina Bhattacharyya, Piruthivi Sukumar, Bithiah Grace Jaganathan

“…Mechanosensor proteins regulate the interaction of the cells with the microenvironment and control several cellular functions. Here, we determined the cellular effects of PIEZO1, a mechanically activated ion channel protein on proliferation, differentiation, migration, and leukemia support of human bone marrow-derived MSCs (BM-MSCs). …”
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Anticholinergic syndrome in the perioperative period (review). Part 1 by O.V. Kravets, V.V. Yekhalov, V.A. Sedinkin, O.V. Pylypenko, D.A. Martynenko

“…The cumulative effect from taking several anticholinergic drugs, known as anticholinergic load, can negatively affect cognitive and physical functions and increase the risk of mortality.…”
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Olive Plant Treated with Different Geo-Material Foliar Film (Zeolite and Kaolin Based): Leaf Characteristics and Oil Quality by Annalisa Rotondi, Tommaso Ganino, Andrea Calderoni, Margherita Rodolfi, Rohini Dhenge, Lucia Morrone

“…However, the reduction in stomatal conductance was attributed to a functional rather than morphological adaptation, as no significant changes in stomatal density or size were observed. …”
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E-commerce operation empowers green agriculture: implication for the reduction of farmers' fertilizer usage by Hailan Qiu, Yi Huang, Weikun Zhang, Bing He, Ruolan Yuan, Zhipeng Wang

“…The heterogeneity analysis shows that e-commerce operation has a heterogeneous impact on FFA regarding gender, agricultural functional zoning, and regional distribution. E-commerce operations can encourage women, major grain-producing areas, and farmers in the central and western regions to reduce fertilizer. …”
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Neutrophil Extracellular Traps Contribute to the Disease Severity of Dengue Virus Infection by Cucunawangsih Cucunawangsih, Ratna Sari Wijaya, Nata Pratama Hardjo Lugito, Ivet Suriapranata

“…Results: Based on the transcriptomic analysis, the whole blood gene expression functional in neutrophil activities and NETs formation was upregulated with dengue disease severity. …”
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Screening and molecular mechanism research on bile microRNAs associated with chemotherapy efficacy in perihilar cholangiocarcinoma by Shijie Fu, Haizhen Du, Yuyang Dai, Kanglian Zheng, Guang Cao, Liang Xu, Yujie Zhong, Chuanxin Niu, Yan Kong, Xiaodong Wang

“…Here, we aimed to screen out HAIC resistance-related bile microRNAs (miRNAs) and explore the functions of specific bile miRNAs in pCCA based on high-throughput sequencing. …”
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METTL3 regulates autophagy of hypoxia-induced cardiomyocytes by targeting ATG7 by Linnan Li, Hao Cheng, Yufei Zhou, Di Zhao, Xiaoxue Zhang, Yajun Wang, Jianying Ma, Junbo Ge

“…Our study shed light on the pivotal role of METTL3-mediated m6A modification in the regulation of autophagy during AMI, providing novel insights into the functional significance of m6A methylation and its regulatory mechanisms.…”
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Calcium is associated with specific soil organic carbon decomposition products by M. C. Rowley, M. C. Rowley, M. C. Rowley, J. Pena, J. Pena, M. A. Marcus, R. Porras, E. Pegoraro, C. Zosso, C. Zosso, N. O. E. Ofiti, N. O. E. Ofiti, G. L. B. Wiesenberg, M. W. I. Schmidt, M. S. Torn, M. S. Torn, P. S. Nico, P. S. Nico

“…Decomposition increases the relative proportion of negatively charged functional groups, which can increase the propensity for the association between SOC and Ca; in turn, this association can inhibit dissolved organic carbon export or further decomposition. …”
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Selumetinib in Adult Neurofibromatosis 1 with Plexiform Neurofibroma by Carlen A. Yuen, Eleanor Chu, Ryan O’Connell, Bryan K. Sun, Raj Vyas, Michelle Zheng, Emma Elliott, Changrui Xiao

“…<b>Background/Objectives:</b> Neurofibromatosis Type 1 (NF1) plexiform neurofibroma (PN) can cause morbidity, including disfigurement that can negatively impact social functioning. Historically, the mainstay treatment is surgical resection. …”
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Increased Th17/Treg Ratio in Poststroke Fatigue by Xinjing Liu, Komal Kenkare, Shanshan Li, Varsha Desai, John Wong, Xun Luo, Lisa J. Wood, Yuming Xu, Qing Mei Wang

“…Serum levels of IL-10 negatively correlated withTh17/Treg ratio (r=-0.408,  p=0.025). …”
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Imidacloprid soil drenches indirectly weaken the selection and predatory ability of the coccinellid predator Propylea japonica (Coleoptera: Coccinellidae) by Jie Zhang, Peng Huang, Yufang Pan, Yi Zhao, Jinai Yao, Deyi Yu

“…In the current study, we examined the indirect impact of imidacloprid soil drenches on prey selection behavior and functional response of the ladybird Propylea japonica. …”
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miR-276 and miR-182013-5p modulate insect metamorphosis and reproduction via dually regulating juvenile hormone acid methyltransferase by Jiasheng Song, Wanwan Li, Lulu Gao, Qiang Yan, Xinyan Zhang, Mingzhi Liu, Shutang Zhou

“…In nymphs, miR-276 binds more to Jhamt, while in adults, miR-182013-5p dominates. Functionally, miR-276 reduced Jhamt and JH levels, shortening nymphal development and inhibiting Vg expression. …”
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