Oncologic effectiveness of open partial vertical laryngectomy in the treatment of early glottic cancer by A. V. Karpenko, R. R. Sibgatullin, A. A. Boyko, O. M. Nikolayeva

“…Smaller operative trauma, absence of tracheostomy, short hospitalization time, and better functional outcomes without compromising oncological outcomes are significant reasons for transition to endoscopic methods. …”
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Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles by Demian van Straten, Luuk van de Schepop, Rowan Frunt, Pieter Vader, Raymond M. Schiffelers

“…Mechanistically, we found that apolipoprotein E, a protein corona component that is crucial for MC3 LNP tropism, displayed reduced stability and functionality upon heat inactivation of FCS, thereby negatively influencing uptake and cargo delivery of MC3 LNPs, but not C12 LNPs. …”
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From stroke to depression: The need for systematic screening for post-stroke depression by Mundih N. Njohjam, Swirri S. Nji, Ebsiy M. Nongse

“…Background: Post-stroke depression (PSD) negatively impacts the physical and mental well-being of stroke survivors. …”
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Physical activity for children and adolescents with attention deficit hyperactivity disorder: a protocol of a systematic review and meta-analysis by Ole Jakob Storebø, Marie-Louise Jensen, Merete Bender Bjerrum, Marianne Vamosi

“…The main objective of the review is to examine the effect of physical activity on QoL, executive functions, symptoms and functional impairment in this population. …”
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Confixal derivatives with initial bez- in Old Russian chronicles by Irina V. Erofeeva, Yulia K. Lukoyanova

“…The aim of the study is a comprehensive structural-semantic, functional, and conceptual analysis of confixal nominal forms with the initial bez- in the Old Russian language. …”
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Identification of Endoplasmic Reticulum Stress-Related Biomarkers in Coronary Artery Disease by Yuanyuan Lin, Lin Ni, Luqun Yang, Hao Li, Zelin Chen, Yuping Gao, Kaiyi Zhu, Yanni Jia, Zhifang Wu, Sijin Li

“…A total of 13 differentially expressed ERS-related genes (DEERSRGs) in CAD were identified. Functional enrichment analysis demonstrated the DEERSRGs were mainly enriched in endoplasmic reticulum (ER)-related pathways. …”
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Association between medication adherence and health-related quality of life among type 2 diabetic adults in Mexico by Sara I. Olvera-Cruz, Araceli Cano-Estrada, José Á. Hernández-Mariano, Ana C. Castañeda-Márquez, Yaneth C. O. Orihuela, María A. Mejía-Blanquel

“…After adjusting for confounders, we observed that non-adherent adults were more likely to have poor HRQoL in six domains of SF-36: physical functioning (adjusted odds ratio [ORa] =2.02; 95% confidence interval [95% CI] =1.06, 3.80); physical role (ORa = 2.37; 95% CI = 1.13, 4.96); bodily pain (ORa = 2.71; 95% CI = 1.45, 5.06); general health (ORa = 2.57; 95% CI = 1.37, 4.80); vitality (ORa = 3.30; 95% CI = 1.70, 6.39); social functioning (ORa = 2.97; 95% CI = 1.56, 5.65); and mental health (ORa = 2.66; 95% CI = 1.42, 4.98). …”
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Prevention and treatment of social anxiety disorder in adolescents: mixed method randomised controlled trial of the guided online intervention SOPHIE by Noemi Walder, Thomas Berger, Dominique Hürzeler, Emily McDougal, Julian Edbrook-Childs, Stefanie J. Schmidt

“…Abstract Social anxiety symptoms are highly prevalent in adolescents and negatively impact their social and academic functioning, highlighting the need for effective low-threshold interventions. …”
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The ubiquitin ligase ASB4 promotes trophoblast differentiation through the degradation of ID2. by W H Davin Townley-Tilson, Yaxu Wu, James E Ferguson, Cam Patterson

“…The transcriptional regulator Inhibitor of DNA binding 2 (ID2) negatively regulates vascular differentiation during development and is a target of many ubiquitin ligases. …”
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Ophthalmic examination in the debut and during progression of neurodegenerative diseases by A. Zh. Fursova, Yu. A. Gamza, M. Yu. Zubkova, A. S. Derbeneva, O. B. Doronina, K. S. Doronina, N. V. Bulatova, A. S. Belgibaeva

“…Microcirculatory disorders lead to retinal changes, which were proven to correlate negatively with the thickness of inner retinal layers and duration of the disease. …”
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RIOK1: A Novel Oncogenic Driver in Hepatocellular Carcinoma by Chunyan Ruan, Tianyu Shang, Sijia Zhang, Wenhong Ru, Yuefeng Yang, Yi Shen

“…Methods Changes in RIOK1 expression in HCC and patient prognosis were evaluated using HCC tissues and public databases. The functional role of RIOK1 in HCC was analyzed by RTCA assay, clonogenic assay, and flow cytometry in vitro, and by mouse tumor xenograft model in vivo. …”
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The effect of plant extracts on antioxidant potential, microbial and sensory attributes of stirred yoghurt by Oktay Tomar, Gökhan Akarca, Abdullah Çağlar, Ömer İstek, Veli Gök

“…According to the results of sensory analysis, the addition of 0.1% plant extracts to yoghurts rated higher scores than that of the control sample, but the addition of 0.3% and 0.5% ethanol extracts negatively affected the sensory properties. It can be concluded that adding plant extracts had a positive effect on the sensory and functional properties of yoghurt.…”
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Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6. by Taha Y Taha, Shahrzad Ezzatpour, Jennifer M Hayashi, Chengjin Ye, Francisco J Zapatero-Belinchón, Julia A Rosecrans, Gabriella R Kimmerly, Irene P Chen, Keith Walcott, Anna Kurianowicz, Danielle M Jorgens, Natalie R Chaplin, Annette Choi, David W Buchholz, Julie Sahler, Zachary T Hilt, Brian Imbiakha, Cecilia Vagi-Szmola, Mauricio Montano, Erica Stevenson, Martin Gordon, Danielle L Swaney, Nevan J Krogan, Gary R Whittaker, Luis Martinez-Sobrido, Hector C Aguilar, Melanie Ott

“…Viral entry and RNA replication were negatively correlated, suggesting that as variants evolve reduced entry functions under growing immune pressure on Spike, RNA replication increases as a compensatory mechanism. …”
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Are people willing to share living space? Household preferences in Finland by Enni Ruokamo, Eliisa Kylkilahti, Michael Lettenmeier, Anne Toppinen

“…Larger floor area per inhabitant is negatively associated with the willingness to share spaces. …”
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Aboveground Biomass in West African Semi‐Arid Ecosystems: Structural Diversity, Taxonomic Contributions and Environmental Drivers by Kangbéni Dimobe, Shem Kuyah, Korotimi Ouédraogo, Ebagnerin Jérôme Tondoh, Adjima Thiombiano

“…ABSTRACT The role of plant diversity and biomass in ecosystem functioning and management is well recognized. However, the structural drivers of aboveground biomass (AGB) and their influence across savanna ecosystems remain understudied, particularly in semi‐arid regions. …”
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The immunomodulatory effects of sodium new houttuyfonate on different states of macrophage against Aspergillus fumigatus infection via distinct mechanism in invasive pulmonary aspe... by Xue Zhou, Fujiao Huang, Jinping Zhang, Shu Gong, Liwen Wei, Fangyang Liu, Zhangyong Song

“…What’s more, SNH inhibited the expression of miR-328-5p and miR-6975-3p in MH-S cells, which negatively regulated TLR2 expression and the phagocytosis and killing functions of MH-S cells. …”
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Fecal Microbiota Underlying the Coexistence of Schizophrenia and Multiple Sclerosis in Chinese Patients by Li Shao, Jinlong Fu, Lulu Xie, Guangyong Cai, Yiwen Cheng, Nengneng Zheng, Ping Zeng, Xiumei Yan, Zongxin Ling, Shiwei Ye

“…Considering that fecal microbiota played a vital role in regulating brain functions, the fecal microbiota and serum cytokines from 90 SZ patients and 71 age-, gender-, and BMI-matched cognitively normal subjects (referred as SZC), 22 MS patients and 33 age-, gender-, and BMI-matched healthy subjects (referred as MSC) were analyzed. …”
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Abundance, Diversity and Phenology of Mosquito Larvae in a Highly Anthropized Wetland: Health and Management Implications of Gándaras de Budiño (NW Spain) by Yasmina Martínez‐Barciela, Alejandro Polina, Josefina Garrido

“…Although almost all functional groups contain some mosquito capable of transmitting diseases, only Cx. pipiens s.l. …”
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Valproic acid induces ferroptosis and suppresses the proliferation of MDA-MB-231 cells by targeting FDFT1 by Shuxian Zhang, Jiazhuo Liu, Yisong Yang, Ran Tao, Xin Ren, Xingzhi Zhou, Shuangping Liu

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A magnetic resonance imaging and gut flora-based study of intake desire in overweight/obese type 2 diabetes mellitus patients by Mingxuan Gao, Liya Gong, Yanmei Zeng, Dongling Li, Junyan Wen, Ying Guo, Zhujia Li, Jingwen Luo, Chunling Chen, Ge Wen

“…Meanwhile, in Group A and Group B, and Bifidobacterium were negatively correlated with HbA1c, thirst score, and FC values of the left supraoccipital gyrus and bilateral thalamus in the population with abnormal glucose metabolism; Bacteroides were negatively correlated with ALFF values of the right inferior frontal gyrus capitellum, and positively correlated with FC values of the left supraoccipital gyrus and bilateral thalamus, and so on.ConclusionAbnormal desire to ingest is the result of functional changes in brain regions, dysregulation of flora metabolism and neuroimmune interactions, providing a theoretical basis for clinical diagnosis and treatment targeting the gut-brain axis.…”
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