Objective approach in the assessment of speech quality in patients with tongue cancer after hemiglossectomy by Ch. A. Ganina, M. A. Kropotov, O. A. Saprina, E. V. Kosova, V. Zh. Brzhezovskiy, D. I. Novokhrestova, M. T.  Isaeva, Е. A. Grivachev

“…Surgery is the leading treatment for tongue cancer, performance which leads to impaired speech function. Because speech is one of the most important tools of social interaction, its disorder can significantly affect patients’ quality of life. …”
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“THEY ORDER…THIS MATTER BETTER IN FRANCE”. YORICK THE PHILOSOPHER AND SENTIMENTAL TRAVELLER by Elena V. Maksiutenko

“…According to Battestin, Sterne’s emphasis on the liberating function of human sexuality is important. Claiming a spiritual value for eroticism Sterne turns to be the precursor of D. …”
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Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy by Christoforos K. Vaxevanis, Marcus Bauer, Karthikeyan Subbarayan, Michael Friedrich, Chiara Massa, Katharina Biehl, Haifa Kathrin Al-Ali, Claudia Wickenhauser, Barbara Seliger

“…BGN expression in BMBs positively correlated with MUM1+ and CD8+, but negatively with CD33+TLR4+ cell infiltration and was accompanied by a decreased progression-free survival of MDS patients. …”
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Addressing inhaler technique challenges in cognitively impaired chronic obstructive pulmonary disease patients: the impact of customized training programs by Vaishnavi V Gaonkar, Vinay V Shanbhag, Shreya S Kajave, Mahek R Mattikop, Mandati Santhosh Reddy

“…Correlational analysis revealed MoCA scores were negatively associated with the number of mistakes (r=-0.344). …”
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Combined effect of cinnamon essential oil-chitosan coating and modified atmosphere packaging on the quality of chilled meat by ZHOU Qiang, LIU Mengjia, ZHANG Baoshan, LEI Changgui, MENG Yuzhu

“…The above indicators were negatively correlated with a* and elasticity (P<0.01). …”
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Tanshinone IIA Alleviates Traumatic Brain Injury by Reducing Ischemia‒Reperfusion via the miR-124-5p/FoxO1 Axis by Wenbing Su, Meifen Lv, Dayu Wang, Yinghong He, Hui Han, Yu Zhang, Xiuying Zhang, Shaokun Lv, Liqing Yao

“…After treatment with Tanshinone IIA in middle cerebral artery occlusion–reperfusion (MCAO/R) rats, the volume of cerebral infarction was reduced, the water content of the brain was decreased, the nerve function of the rats was significantly improved, and the cell damage was significantly reduced. …”
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Clinical and demographic data and the significance of various dysfunctions and severity indicators in multiple sclerosis patients by Gennadii M. Chupryna, Natalia V. Khanenko

“…This is because the consequences of inflammation, demyelination, and neurodegeneration often negatively affect both the afferent and efferent parts of visual function, significantly worsening the quality of life of patients with multiple sclerosis. …”
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Correlation of intestinal bacteria, fungi and dietary nutrient intake in NAFLD patients with spleen deficiency syndrome by Guiru Lin, Wanyi Ou, Jianmei Yang, Dongliang Chen, Yuanfei Wang, Aiping Wu, Lilian Gao, Wan Qu, Chenli Lin, Chenli Lin, Yinji Liang, Yinji Liang

“…The independent and interactive effects of intestinal bacteria and fungi might have collectively influenced the immune function and inflammation levels in NAFLD patients with SDS. …”
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Improved aerobic capacity in a randomized controlled trial of noncombustible nicotine and tobacco products by Lucia Spicuzza, Francesco Pennisi, Grazia Caci, Fabio Cibella, Davide Campagna, Yusuff A. Adebisi, Claudio Saitta, Jacob George, Giulio Geraci, Riccardo Polosa

“…Abstract Smoking negatively impacts aerobic capacity, primarily by reducing V̇O2max, the gold standard measure of cardiorespiratory fitness. …”
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Biochemical, coagulation, and platelet count profiles among Schistosoma mansoni infected patients attending at selected Dembiya health institutions, Northwest Ethiopia by Wagaw Abebe, Wossenseged Lemma, Yalewayker Tegegne, Assefa Sisay, Tadesse Misganaw, Sisay Ayana, Desie Kasew, Marye Nigatie Debash, Alemu Birara Zemariam, Tadele Emagneneh, Adane Derso

“…This is due to liver failure, platelet destruction, disruption of blood flow, and endothelial function by the schistosomes. However, there is no adequate data on biochemical and coagulation profiles and platelet count of patients infected with Schistosoma mansoni in Dembiya Selected Health Institutions. …”
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Complement C3a promotes the formation of osteoclasts by inhibiting Sirt1 to activate the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma by Fengjuan Jiang, Yunhe Zhang, Fengping Peng, Hui Liu, Kai Ding, Panpan Cao, Xiaohan Liu, Lijuan Li, Zhaoyun Liu, Rong Fu

“…Sirt1 inhibits osteoclast formation and complement C3a reverses this inhibitory function of Sirt1 to activate osteoclasts. RAW264.7 cells with induced overexpression or knockdown Sirt1 were transfected with plasmid or shRNA, and RNA-seq analysis was performed. …”
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Leukocyte Dysregulation and Biochemical Alterations in End-Stage Kidney Disease Patients Under Hemodialysis by Gabriela Goyoneche Linares, Daysi Zulema Diaz-Obregón, Ana Granda Alacote, Michael Bryant Castro Núñez, María Gracia Castañeda Torrico, Alexis Germán Murillo Carrasco, Cesar Liendo Liendo, Katherine Susan Rufasto Goche, Víctor Arrunátegui Correa, Joel de León Delgado

“…Background: Patients with chronic kidney disease (CKD) exhibit changes in leukocyte dynamics, leading to altered hematological and biochemical parameters and deteriorating kidney function. In this study, we aim to investigate the correlation between leukocyte subpopulations and hematological and biochemical parameters in patients with end-stage CKD undergoing hemodialysis. …”
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Peculiarities of clinical and metabolic profile of patients with coronary artery disease associated with type 2 diabetes mellitus (retrospective analysis) by N. S. Mykhailovska, T. O. Kulynych, O. V. Shershnova, Ye. I. Bazun, I. S. Bocharnykova, V. E. Padafa, A. O. Kolesnykova, Yu. V. Hura

“…Concomitant diabetes mellitus affects negatively the course of CAD by increasing the frequency of arrhythmias and atherothrombotic events. …”
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The effects of normal and interrupted sleep combined with acute caffeine supplementation on some immune system indices and anaerobic power in male athletes by Mohammad hossein Hashemzadeh, Farhad Rahmaninia, Payam Saidie

“…Therefore, considering the improvement in immune function markers under sleep deprivation with caffeine supplementation, even without enhancing anaerobic performance, and the fact that sleep deprivation strongly activates the body's inflammatory signaling network, the use of this supplement can be recommended for athletes in conditions of sleep deprivation and before intense activities.…”
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Deciphering the microbiome–metabolome landscape of an inflammatory bowel disease inception cohort by Shiva T. Radhakrishnan, Benjamin H. Mullish, Marton L. Olbei, Nathan P. Danckert, Maria A. Valdivia-Garcia, Jose I. Serrano-Contreras, Despoina Chrysostomou, Sharmili Balarajah, Robert W. Perry, John P. Thomas, Lejla Potari-Gul, Dezso Modos, Lucy C. Hicks, Nick Powell, Timothy R. Orchard, Jia V. Li, Julian R. Marchesi, Tamas Korcsmaros, James L. Alexander, Horace R. T. Williams

“…Networks from IBD patients overall showed negative correlation with health-specific associations, including an increase in taurine metabolism. …”
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Inhibition of NK cell cytotoxicity by tubular epithelial cell expression of Clr-b and Clr-f by Benjamin Fuhrmann, Jifu Jiang, Patrick Mcleod, Xuyan Huang, Shilpa Balaji, Jaqueline Arp, Hong Diao, Shengwu Ma, Tianqing Peng, Aaron Haig, Lakshman Gunaratnam, Zhu-Xu Zhang, Anthony M. Jevnikar

“…Kidney tubular epithelial cells (TECs) may negatively regulate NK cell activation by their surface expression of a complex family of C-type lectin-related proteins (Clrs). …”
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Tripartite Motif Containing 65 Deficiency Confers Protection Against Acute Kidney Injury via Alleviating Voltage‐Dependent Anion Channel 1–Mediated Mitochondrial Dysfunction by Tao Chen, Yang Zhang, Liting Ding, Chenlu Xiong, Chao Mei, Sisi Wei, Ming Jiang, Yingjie Huang, Jianrong Chen, Tao Xie, Qing Zhu, Qi Zhang, Xuan Huang, Shibiao Chen, Yong Li

“…Conversely, the overexpression of VDAC1 in renal tissues has been demonstrated to negate the protective effect of TRIM65 deficiency on AKI. …”
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Oxidative Stress on <i>Haemonchus contortus</i> Larvae Exposed to Alternative Treatment with <i>Artemisia cina n</i>-Hexane Extract and Cinaguaiacin Metabolites by Ana Elvia Sánchez-Mendoza, Guillermo Reséndiz-González, Eduardo Rico-Mejía, Héctor Alejandro de la Cruz-Cruz, Gerardo Ramírez-Rico, Jorge Alfredo Cuéllar-Ordaz, José Francisco Montiel-Sosa, María Eugenia López-Arellano, David Emmanuel Reyes-Guerrero, Clara Luisa Domínguez-Delgado, Martín Orlando Pulido Medellín, Daniel Hernández-Patlán, Rosa Isabel Higuera-Piedrahita

“…Anthelmintic resistance is currently negatively impacting animal production parameters, leading to an increase in the prevalence of gastrointestinal nematodes and resulting in low profitability in small ruminants. …”
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The Efficiency of Complex Differential Treatment of the Patients with Systemic Lupus Erythematous Considering the Features of Bone Tissue Structure Remodeling by Abrahamovych U., Tsyhanyk L., Abrahamovych O., Farmaha M., Romaniuk O.

“…This allows us to define 4 groups of patients: І (16 patients, 28.07 %) – with low content of vitamin D (<30.0 ng/l), preserved osteoblast and osteoclast functions, ІІ (4 patients, 7.02 %) – with the lack of vitamin D (<30.0 ng/l), with preserved osteoblast and osteoclast functions; ІІІ (16 patients, 28.07 %) – with the lack of vitamin D (<30.0 ng/l), with a weakened osteoblast and osteoclast functions; ІУ (19 patients, 33.33 %) – with the lack of vitamin D (<30.0 ng/l), with a weakened osteoblast and osteoclast functions. …”
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Ring finger protein 5 mediates STING degradation through ubiquitinating K135 and K155 in a teleost fish by Xiaowei Qin, Chuanrui Li, Mincong Liang, Zhen Qian, Yanlin You, Shaoping Weng, Jianguo He, Jianguo He, Changjun Guo, Changjun Guo

“…In mammals, ring finger protein 5 (RNF5) functions as an E3 ubiquitin ligase, mediating STING regulation through K150 ubiquitylation to prevent excessive IFN production. …”
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