Integrated multi-omics to elucidate the interplay between rumen microorganisms and host metabolism in Hu sheep supplemented with herbal preparations by Chunhui Wang, Qiao Li, Xingcai Qi, Huihui Wang, Yi Wu, Keyan Ma, Juanjuan Song, Zilong Liu, Youji Ma

“…It was also found that the addition of herbal preparations enhanced antiviral and anti-inflammatory responses, nutrient metabolism, immune function, and stimulation of rumen microbial activity as well as facilitated the acceleration of body metabolism in Hu sheep.…”
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ECONOMIC AND LEGAL CHARACTERISTICS OF PUBLIC AUTHORITIES OF UKRAINE by Oleg Dubynskyy, Dmytro Baranenko, Vitalii Porkhun

“…Secondly, public authorities have a significant impact on society, and it is important to understand how they function. Thirdly, the study of public authorities can help to develop effective methods of governing society. …”
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Curcumin alleviates LPS-induced WI-38 cell inflammation injury by regulating PTGS2 expression by Hongli Xiao, Wangsheng Ma, Lin Zha, Yanmin Xiao, Hui Li

“…CUR abolished LPS-induced regulation WI-38 cell biological functions. Besides, the 16 hub genes from potential target genes of CUR and infantile pneumonia were screened. …”
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ARTISTIC TRINITY: LITERATURE – CINEMA – MUSIC (THE FILM “EARTH” BY O. DOVZHENKO) by Larysa M. Gorbolis, Anna Ye. Chernysh

“…There are a music tempo-rhythmic and tonal-emotional support of frames in the film, that as well performs a peculiar function of sound illustration in the corresponding episodes of the literary text, thus giving the images of main characters and minor characters dynamics and expression. …”
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Speech-language therapy and occupational therapy for patients with mild cognitive impairment and dementia: a retrospective cohort study using German health claims data by Fiona Dörr, Daniela Holle, Bashar Morouj, Dominik Obermüller, Sascha Sommer, Markus Wübbeler, Kerstin Bilda

“…Abstract Background Dementia is a complex, multifactorial syndrome characterised by cognitive decline and impaired daily functioning, representing a major risk factor for long-term care dependency. …”
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Predictive role of SLC1A5 in neuroblastoma prognosis and immunotherapy by Jian Cheng, Miaomiao Sun, Xiao Dong, Yang Yang, Xiaohan Qin, Xing Zhou, Yongcheng Fu, Yuanyuan Wang, Jingyue Wang, Da Zhang

“…Functional validation included qPCR, immunohistochemistry, Western blotting, and cell proliferation assays using the SLC1A5 inhibitor V-9302. …”
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Psychological predictors and “protectors” of students’ Internet addiction by A. A. Kolmogortseva, E. A. Rylskaya

“…At the same time, reflexivity and vitality act as “protectors” and perform a protective function in the emergence of Internet addiction, allowing the individual to remain an open self-developing system.Scientific novelty. …”
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Expression and Prognostic Significance of PDIA3 in Cervical Cancer by Jing Zhang, Hui Li, Huling Li, Dandan Lin, Xiaoyan Wang, Kai Wang

“…To investigate the expression of protein disulfide isomerase A3 (PDIA3/ERP57) in cervical cancer and its clinical prognostic significance as well as its function and possible action mechanism in the progression of cervical cancer. …”
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Early detection of left atrial dysfunction in young hypertensive patients with a normal left atrial size: a comprehensive analysis using four-dimensional auto left atrial quantific... by Luyi Ping, Yulin Huang, Gufeng Sun, Lin Jin, Xu Huang, Chunquan Zhang, Jiwei Wang

“…Abstract Background This study aimed to detect early left atrial (LA) function abnormalities in young hypertensive patients with a normal two-dimensional LA volume index (2D-LAVI) using four-dimensional auto LA quantification technology (4D Auto LAQ) and to analyse correlations between LA strain parameters and clinical metabolic indicators. …”
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HEMOPHILIA: ADVANCES IN TREATMENTS by Nurgül Karakaya

“…Inhibitor development impacts negatively upon quality of life and treatment compliance, highlighting the need for improved therapies. …”
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Egg exosome miR-145-5p decreases mitochondrial ROS to protect chicken embryo hepatocytes against apoptosis through targeting MAPK10 by Fengdong Zhang, Yongchang Han, Fan Li, Boya Guo, Jian Chen, Wenchuan Zhou, Pan Xiao, Hui Ma, Yongyan Jin, Jia Feng, Yuna Min

“…Abstract Background Higher embryonic mortality, especially in aged breeding hens, is associated with insufficient hepatic functionality in maintaining redox homeostasis. Our previous study demonstrated that egg exosome-derived miRNAs may play a key role in modulating embryonic oxidation-reduction process, whereas the exact function and mechanism were still poorly understood. …”
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Academic performance and its associated factors among khat-chewer and non-khat chewer high school students in Ethiopia, 2023 by Tilahun Tesfa, Tilahun Belete Mossie, Meseret Tadesse, Yonas Deressa Guracho, Yonas Deressa Guracho, Birhanu Mengist Munie

“…Regular khat consumption can negatively affect neurocognitive function, decision-making, and problem-solving abilities, leading to decreased academic achievement, especially in Ethiopia. …”
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Associations between amino acid levels and autism spectrum disorder severity by Jing Li, Panpan Zhai, Liangliang Bi, Ying Wang, Xiaoqing Yang, Yueli Yang, Nan Li, Weili Dang, Gang Feng, Pei Li, Yuan Liu, Qiushuang Zhang, Xiaofeng Mei

“…Amino acid metabolism abnormalities are particularly relevant to ASD pathology due to their crucial role in neurotransmitter synthesis, synaptic function, and overall neurodevelopment. This study aims to explore the association between amino acid metabolic abnormalities and the severity of ASD by analyzing the amino acid concentrations in the blood of children with ASD. …”
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The association of ultra-processed food intake on age-related muscle conditions: a systematic review and dose–response meta-analysis with meta-regression by Mohammad Ali Hojjati Kermani, Farhang Hameed Awlqadr, Sepide Talebi, Sanaz Mehrabani, Donny M. Camera, Reza Bagheri, Fariborz Poorbaferani, Seyed Mojtaba Ghoreishy, Parsa Amirian, Mahsa Zarpoosh, Sajjad Moradi

“…These findings suggest that regular consumption of UPFs may negatively affect muscle health, potentially impairing quality of life and independence in older adults.…”
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Comparative transcriptomics reveal stage-dependent parasitic adaptations in the myxozoan Sphaerospora molnari by Monika M. Wiśniewska, Jiří Kyslík, Gema Alama-Bermejo, Alena Lövy, Martin Kolísko, Astrid S. Holzer, Anush Kosakyan

“…We performed stage-specific transcriptomic profiling to identify differentially expressed key functional gene groups that relate to these functions and provide a fundamental understanding of the mechanisms S. molnari uses to optimize its parasitic lifestyle. …”
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Patient and caregiver experiences with a patient-support program for setmelanotide treatment of patients with Bardet–Biedl syndrome by Ilja Finkelberg, Ioanna M. Polichronidou, Tom Hühne, Pia Brensing, Sinem Karaterzi, Johannes Jaegers, Anja Gäckler, Lars Pape, Metin Cetiner

“…Abstract Background Bardet–Biedl syndrome (BBS) is a rare genetic disease caused by impaired cilium function and characterized by a plethora of symptoms, including hyperphagia and early-onset obesity, that negatively affect patient and caregiver quality of life. …”
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Factors influencing the cure of pseudolithiasis: a retrospective study of 264 patients by Leijiao Deng, Jie Deng

“…The underlying inflammatory gallbladder diseases and their treatments may facilitate the rapid resolution of pseudolithiasis, while factors such as viral hepatitis and decompensated cirrhosis may affect liver function and bile composition but do not appear to directly contribute to the occurrence of pseudolithiasis. …”
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A novel ubiquitin-related genes-based signature demonstrated values in prognostic prediction, immune landscape sculpture and therapeutic options in laryngeal cancer by Lu Liu, Lu Liu, Lu Liu, Lu Liu, Bing Wang, Xiaoya Ma, Xiaoya Ma, Lei Tan, Lei Tan, Lei Tan, Xudong Wei, Xudong Wei

“…PPARG and LHX1 were negatively correlated, whereas LCK positively correlated, with the immuno-promoting microenvironment. …”
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Exploring Factors Related to Social Isolation Among Older Adults in the Predementia Stage Using Ecological Momentary Assessments and Actigraphy: Machine Learning Approach by Bada Kang, Min Kyung Park, Jennifer Ivy Kim, Seolah Yoon, Seok-Jae Heo, Chaeeun Kang, SungHee Lee, Yeonkyu Choi, Dahye Hong

“…Social isolation—which includes limited social interaction and feelings of loneliness—negatively affects cognitive function and is a significant risk factor for dementia. …”
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The benefit of a frailty clinician in aiding triage within the emergency department to help eliminate corridor care by Jay Acharya, Amir Manzoor, Radcliffe Lisk

“…It highlights the increasing pressures within the NHS, including overcrowding, staff shortages and subsequent increased demand on stretched resources.Corridor care can negatively impact patient dignity and safety. Despite these issues, it provides a broader challenge in healthcare capacity and planning. …”
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