Effects of Human Mesenchymal Stem Cells Isolated from Wharton’s Jelly of the Umbilical Cord and Conditioned Media on Skeletal Muscle Regeneration Using a Myectomy Model by T. Pereira, P. A. S. Armada-da Silva, I. Amorim, A. Rêma, A. R. Caseiro, A. Gärtner, M. Rodrigues, M. A. Lopes, P. J. Bártolo, J. D. Santos, A. L. Luís, A. C. Maurício

“…The treated groups obtained interesting results in terms of muscle regeneration, both in the histological and in the functional assessments. A less evident scar tissue, demonstrated by collagen type I quantification, was present in the muscles treated with HMSCs or their CM. …”
Get full text

lncRNA <i>EGOT</i> Is the Marker of HPV Infection and a Prognostic Factor for HNSCC Patients by Tomasz Kolenda, Piotr Białas, Kacper Guglas, Maciej Stasiak, Joanna Kozłowska-Masłoń, Karina Tylkowska, Anna Zapłata, Paulina Poter, Marlena Janiczek-Polewska, Patrycja Mantaj, Paulina Gieremek, Urszula Kazimierczak, Anna Przybyła, Katarzyna Regulska, Beata Stanisz, Ewa Leporowska, Andrzej Mackiewicz, Jacek Mackiewicz, Joanna Kazmierska, Zefiryn Cybulski, Anna Teresiak

“…<b>Background:</b> High-risk human papillomavirus (HPV) contributes to oropharyngeal cancers through mechanisms involving the deregulation of host cell functions by oncoproteins E6 and E7. Changes in the epigenome, particularly involving long non-coding RNAs (lncRNAs), are crucial for understanding HPV-related carcinogenesis. …”
Get full text

Thyroid Parameters and Kidney Disorder in Type 2 Diabetes: Results from the METAL Study by Yi Chen, Wen Zhang, Ningjian Wang, Yuying Wang, Chiyu Wang, Heng Wan, Yingli Lu

“…After full adjustment, linear regression showed that UACR levels were negatively associated with FT3 and T3 (P<0.001). In addition, eGFR was positively associated with FT3 and T3 and was negatively associated with TSH and FT4 levels and TgAb positivity (all P<0.05). …”
Get full text

Identification of the Cold-Related Genes COLD11 and OsCTS11 via BSA-seq and Fine Mapping at the Rice Seedling Stage by Bian Wu, Minghui Fu, Jinghua Du, Mengjing Wang, Siyue Zhang, Sanhe Li, Junxiao Chen, Wenjun Zha, Changyan Li, Kai Liu, Huashan Xu, Huiying Wang, Shaojie Shi, Yan Wu, Peide Li, Aiqing You, Lei Zhou

“…Abstract Cold stress has a significantly negative effect on the growth, development, and yield of rice. …”
Get full text

Nanofabricated Bacterial Cell Walls with Intrinsic Peroxidase‐Mimicking and Sonodynamic Activities for Cancer Combination Treatment by Meng Yang, Yang Meng, Junling Li, Liya Bai, Yuanyuan Cheng, Yuanyuan Liu, Mingxin Cao, Xiaoying Yang, Yinsong Wang, Yang Liu

“…Abstract Bacterial cancer therapy recently has been attracting more and more attention because of its multiple functions to fight cancer. Porphyromonas gingivalis (Pg), a Gram‐negative pathogenic bacterium, acquires protoporphyrin IX (PpIX) and iron from heme and synthesizes abundant µ‐oxo bisheme on its cell walls (CWs). …”
Get full text

A study of morpho-phonological processes in the Zanjani dialect of Azerbaijani Turkish based on optimality theory by farnaz ebadi, Mohammad Reza Oroji, Sakine Jafari, Mehri Talkhabi

“…The accusative suffix (I), negation suffix (sIz), and subjunctive suffix (In) both harmonize with the back/front and the round/non-round features with the final vowel in the preceding root. …”
Get full text

Coordinated improvement of maize grain yield and protein quality by the ZmMADS8-ZmMADS47-O2 module and a G protein gamma subunit by Yunfu Li, Qiang Ning, Ran Zhao, Dan Liu, Nan Li, Qing Xiong, Qin Sun, Yanfang Du, Ruijie Mao, Jimin Zhan, Zuxin Zhang, Lei Liu

“…Here, we characterized the functions of the MADS domain-containing protein ZmMADS8 and Zea mays G protein gamma subunit 1 (ZmGG1) in regulating protein quality and grain yield of maize. …”
Get full text

Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Despite its well-documented benefits in mammalian cellular processes, its functions and underlying mechanisms in plants remain unclear. …”
Get full text

The GntR/VanR transcription regulator AlkR represses AlkB2 monooxygenase expression and regulates n‐alkane degradation in Pseudomonas aeruginosa SJTD‐1 by Wanli Peng, Xiuli Wang, Qinchen Liu, Zhihong Xiao, Fulin Li, Nannan Ji, Zhuo Chen, Jiaying He, Junhao Wang, Zixin Deng, Shuangjun Lin, Rubing Liang

“…In this study, we identified a GntR/VanR transcription regulator AlkR of Pseudomonas aeruginosa SJTD‐1 involved in the negative regulation of AlkB2 and deciphered its nature of DNA binding and ligand release. …”
Get full text

Integrated Transcriptome and Metabolome Analysis Reveals Candidate Genes and Regulatory Pathways Shaping Duck Meat Color by Shuaixue Jiang, Zhao Yang, Yinjuan Lu, Tao Zhang, Mengru Xu, Xu Han, Qiuyu Tao, Yuan Bai, Xinxin He, Bo Han, Junsheng Zhu, Liang Li, Anqi Huang, Lili Bai, Jiwei Hu, Hehe Liu

“…Although the effects of these genes and pathways on meat color have been discovered, their specific genetic mechanisms and molecular functions still need further verification. This provides important clues for further understanding the molecular mechanism of meat color formation and may offer potential molecular targets for improving meat color or breeding new varieties.…”
Get full text

SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis by Fenglei Huo, Chenghang Liu, Xi Wang, Jinzheng Li, Zhifeng Wang, Duanqin Liu, Weipeng Lan, Xingyan Zhu, Jing Lan

“…Additionally, SDCCAG3 was subjected to negative transcriptional regulation by PPARγ, forming a SDCCAG3-PPARγ-SDCCAG3 loop that enhanced adipocyte lipid metabolism. …”
Get full text

Clinical and laboratory aspects of patients diagnosed with various inherited platelet disorders by Veysel Gök, Alper Ozcan, Fatma Türkan Mutlu, Ebru Yılmaz, Deniz Kocak Göl, Mustafa Ozay, Baver Demir, Hüseyin Taskiran, Hasan Bas, Mehmet Burak Mutlu, Muhammet Ensar Dogan, Atil Bisgin, Ido Somekh, Meino Rohlfs, Munis Dundar, Yusuf Ozkul, Christoph Klein, Musa Karakukcu, Ekrem Unal

“…There was a moderate, negative, statistically significant correlation between platelet counts and bleeding severity. …”
Get full text

The aperiodic and periodic activities of EEG dynamically relate with cognitive performance in schizophrenia by Kexin Zhang, Yunfei Ji, Xiaodong Guo, Tianqi Gao, Xuemin Zhang, Xin Yu, Jing Wang

“…The findings suggest that aperiodic exponent holds strong cognitive functional implications in SCZ.…”
Get full text

Phyto-fabrication of copper oxide nanoparticles (NPs) utilizing the green approach exhibits antioxidant, antimicrobial, and antifungal activity in Diospyros kaki fruit by Iftikhar Hussain Shah, Irfan Ali Sabir, Muhammad Ashraf, Asad Rehman, Zishan Ahmad, Muhammad Azam, Ghulam Abbas Ashraf, Haroon ur Rasheed, Guohui Li, Jeridi Mouna, Mohammad Faizan, Muhammad Ahsan Altaf, Awais Shakoor, Cheng Song, Muhammad Aamir Manzoor

“…The FTIR analysis revealed the functional groups present in plant extracts. XRD was carried out to demonstrate the crystalline nature and size of nanoparticles using the Scherrer formula. …”
Get full text

SSB expression is associated with metabolic parameters of 18F-FDG PET/CT in lung adenocarcinoma and can improve diagnostic efficiency by Zi-Yue Liu, Ling-Ling Yuan, Yan Gao, Yu Zhang, Yao-Hua Zhang, Yi Yang, Yu-Xuan Chen, Xu-Sheng Liu, Zhi-Jun Pei

“…Purpose: The study evaluates the expression and functional significance of the Small RNA Binding Exonuclease Protection Factor La (SSB) gene in lung adenocarcinoma (LUAD). …”
Get full text

Genomic and Metabolomic Analysis of the Endophytic Fungus <i>Alternaria alstroemeriae</i> S6 Isolated from <i>Veronica acinifolia</i>: Identification of Anti-Bacterial Properties a... by Farkhod Eshboev, Alex X. Gao, Akhror Abdurashidov, Kamila Mardieva, Asadali Baymirzaev, Mirzatimur Musakhanov, Elvira Yusupova, Shengying Lin, Meixia Yang, Tina T. X. Dong, Shamansur Sagdullaev, Shakhnoz Azimova, Karl W. K. Tsim

“…Comprehensive functional genome annotation analyses, including gene ontology (GO) terms, clusters of orthologous groups (COGs), Kyoto encyclopedia of genes and genomes (KEGG), carbohydrate-active enzymes (CAZymes), and antibiotics and secondary metabolites analysis shell (antiSMASH) analyses, were performed. …”
Get full text

Schizophrenia genetic risk and labour market outcomes in the Finnish general population: Are schizophrenia-related traits penalised or rewarded? by Aaro Hazak, Johanna Liuhanen, Katri Kantojärvi, Sonja Sulkava, Tuija Jääskeläinen, Veikko Salomaa, Seppo Koskinen, Markus Perola, Tiina Paunio

“…Background: Schizophrenia polygenic risk scores (SCZPRS) have been linked to cognitive functioning, creativity, behavioural traits, and psychiatric conditions beyond schizophrenia. …”
Get full text

Transcriptome analysis of insecticide resistance mechanisms in field populations of the bean flower thrips, Megalurothrips usitatus (Bagnall) by Hongyi Cao, Jiangjiang Yuan, Yanran Wan, Yingxi Tang, Xiaobin Zheng, Jing Wang, Kanghua Qian, Jiuming Feng, Sirui Chen, Youjun Zhang, Qingjun Wu

“…RNA sequencing (RNA-seq) and weighted gene co-expression network analysis (WGCNA) techniques validated key gene functions. Results showed that the XW population was resistant to five insecticides, with resistance ratios ranging from 7.17 to 42.90 compared to the reference population. …”
Get full text

SEC61 translocon gamma subunit is correlated with glycolytic activity, epithelial mesenchymal transition and the immune suppressive phenotyp... by Zhou Changshuai, Cui Huanhuan, Yang Yuechao, Chen Lei, Feng Mingtao, Gao Yang, Li Deheng, Li Liangdong, Chen Xin, Li Xiaoqiu, Cao Yiqun

“…Functional studies demonstrate that SEC61G knockdown markedly inhibits the migration of A549 and H2030 LUAD cells. …”
Get full text

Haplotype-resolved genome reveals haplotypic variation and the biosynthesis of medicinal ingredients in Areca catechu L. by Chao Wang, Lei Tan, Zhonghui Zhang, Xianggui Li, Linghao Xia, Peng Cao, Haiyang Tong, Xumin Ou, Shixuan Li, Jianing Zhang, Chun Li, Jun Yang, Wen-Biao Jiao, Shouchuang Wang

“…Further analyses tested the function of AcUGT71CE15, AcUGT74CJ38, AcUGT87EE5 and AcUGT83S982 as glucosyltransferases, and AcUGT78AP14 was identified as a rhamnosyltransferase involved in flavonol glycosylation. …”
Get full text