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10741
Over-activation and dysfunction of platelet-NK cell aggregates in HIV-infected individuals
Published 2025-05-01“…Furthermore, NK cells' cytokine secretion (IFN-γ) and cytotoxic function (Granzyme B and Perforin) within the aggregates were declined. …”
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10742
miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency
Published 2020-01-01“…Serum miR-21, Peli1 mRNA of peripheral blood mononuclear cells (PBMCs) and regulatory T cells (Tregs), general status, spleen Tregs ratio, inflammatory factors, ovarian endocrine function, and ovarian structure were evaluated. For autoimmune POI patients, serum miR-21, PBMCs Peli1 mRNA levels, general data, immune parameters, hormone levels, and ultrasound examinations were obtained. …”
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10743
Pretransplant NT‐proBNP levels are associated with mortality among lung transplant recipients
Published 2024-07-01“…Correlations of NT‐proBNP values with lung function and RHC parameters and all‐cause mortality were analyzed. …”
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10744
Gut microbiota constituents may affect hypertrophic scarring risk through interaction with specific immune cells in a two-step, two-sample Mendelian randomization study
Published 2025-07-01“…The principal aim of this study is to elucidate the causal relationship among gut microbiota (GM), immune cell function, and hypertrophic scarring in a European demographic. …”
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10745
Non-invasive detection of Parkinson’s disease based on speech analysis and interpretable machine learning
Published 2025-04-01“…ObjectiveParkinson’s disease (PD) is a progressive neurodegenerative disorder that significantly impacts motor function and speech patterns. Early detection of PD through non-invasive methods, such as speech analysis, can improve treatment outcomes and quality of life for patients. …”
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10746
Effect of GLP-1 Receptor Agonists (Liraglutide) on Glycemic Parameters and Circulating miRNA Expression in Type 2 Diabetes Mellitus
Published 2025-06-01“…In type 2 diabetes mellitus (T2DM), alteration in miRNA profiles can have a significant effect on insulin signaling, β-cell function, and inflammation. It has been suggested that antidiabetic therapies can normalize circulating miRNA levels and improve metabolic parameters, rendering miRNA as potential biomarkers for T2DM monitoring and treatment response. …”
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10747
Hypomethylation of GCNT2 isoform A correlates with transcriptional expression and is associated with poor survival in acute myeloid leukemia
Published 2025-02-01“…BackgroundThe function of GCNT2 has been documented to act as an oncogenic driver or tumor suppressor in different types of tumor, but the role of GCNT2 and the epigenetic regulation mechanism in AML, however, has not yet been clarified. …”
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10748
LncRNA BACE1-AS delays the propagation of Cryptosporidium parvum through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis
Published 2025-07-01“…The present study enriches our knowledge on the function of host lncRNAs during Cryptosporidium infection and contributes to our understanding of the interaction between hosts and Cryptosporidium.IMPORTANCERecent studies indicate that Cryptosporidium can regulate cell apoptosis to promote its development in host cells, but the mechanism is still unclear. …”
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10749
Hemoglobin glycation index and mortality risk in metabolic dysfunction-associated steatotic liver disease patients: a novel U-shaped association
Published 2025-01-01“…HGI could potentially function as a useful and dependable marker for evaluating all-cause mortality and cardiovascular mortality in MASLD patients.…”
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10750
RBM47 promotes cell proliferation and immune evasion by upregulating PDIA6: a novel mechanism of pancreatic cancer progression
Published 2024-12-01“…The RBM47 expression was negatively correlated with natural killer (NK) cell infiltrate in PC. …”
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10751
Associations of circulating omentin-1 levels and long noncoding RNA MALAT1 expression with coronary heart disease in patients with type 2 diabetes mellitus
Published 2025-05-01“…MALAT1 expression was negatively correlated with LVEF but positively correlated with age and DM duration (P < 0.05). …”
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10752
Clinical value of free ubiquitin in the identification of diabetic nephropathy in patients with type 2 diabetes mellitus and preliminary exploration of its protective effect
Published 2025-07-01“…However, its levels and functional role in diabetic nephropathy (DN) remain unclear. …”
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10753
Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway
Published 2025-07-01“…Conclusions The results indicate that fRJ enhances macrophage phagocytosis through TLR2/MAPK/SR, and L. panisapium M1 primarily contributes to immune function.…”
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10754
The challenging management of malignant ureteral obstruction: Analysis of a series of 188 cases
Published 2024-03-01“…The most common reason for urinary diversion was acute kidney injury (53.3%). Recovery of renal function was observed in 55.8% of the patients after urinary diversion. …”
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10755
Regulatory T Cell Sub-Populations in Patients with Distinct Autoimmune/Inflammatory Diseases With or Without Inborn Errors of Immunity
Published 2025-07-01“…Changes in Treg number or function are implicated in a wide range of autoimmune and inflammatory (AI/I) diseases, with or without underlying inborn errors of immunity (IEI). …”
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10756
Hypertension and cognitive impairment among older persons in rural Northern Uganda: a cross-sectional study
Published 2025-06-01“…Abstract Background Hypertension is common among older adults and negatively affects cognitive function. Available data on this association is mostly from resource-rich settings and has been understudied in resource-limited settings especially rural areas where the majority of older persons live. …”
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10757
RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11
Published 2022-01-01“…The findings were validated using a dual-luciferase reporter assay and western blotting. The functional genes of the PI3K/AKT/mTOR signaling pathway were identified, and the functional significance of miR-7-5p in AML cells was determined using a functional recovery assay. …”
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10758
Process-based measures in high-stakes testing: practical implications for construct validity within military aviation selection
Published 2025-08-01“…Process-based measures typically function by having individuals perform either a novel task or perform a task with novel stimuli. …”
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10759
HSPA4 Expression is Correlated with Melanoma Cell Proliferation, Prognosis, and Immune Regulation
Published 2024-11-01“…Five CpG sites are associated with the prognosis of CMM. HSPA4 is negatively correlated with most immune cells in CMM. …”
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10760