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10661
Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness
Published 2025-06-01“…For each included study, we extracted data supporting (i.e., positive evidence) or not (i.e., negative evidence) the relationship between a specific nucleus/nuclear group and the consciousness.Results167 articles were included leading to 346 pieces of evidence of which 284 were positive. …”
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10662
Bullying and depression among adolescents in East Asia: a scoping review on prevalence rates, risk and protective factors
Published 2025-03-01“…Psychosocial associations of bullying and depression which were similarly found in Western cultures include individual factors of coping style and gender; family factors of functioning and sibling relationships; and community factors of friendship and school-connectedness. …”
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10663
EBV-Derived miR-BART20-3p Influences Proliferation and Migration in EBV-Positive Gastric Cancer Models by Suppressing PPARα
Published 2025-06-01“…Epstein–Barr virus (EBV) is the first oncogenic DNA virus known to encode microRNAs (miRNAs) and has been implicated in the pathogenesis of multiple malignancies, including a distinct subset of gastric cancers (EBV-associated gastric cancer, EBVaGC). However, the functional roles of individual EBV-encoded miRNAs in EBVaGC remain poorly defined. …”
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10664
Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue
Published 2025-05-01“…In this study, we investigated the effects of leptin within extracellular vesicles (EVs) secreted by obese adipose tissue on the functional properties and metabolism of MDA-MB-231 breast cancer cells, a model for triple-negative breast cancer (TNBC).MethodMDA-MB-231 cells were treated with EVs derived from the subcutaneous adipose tissue of eutrophic (EUT EVs) and obese (OB EVs) individuals.ResultsOur findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”
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10665
An Empirical Analysis of Herding Behavior in the Stock Market: Evidence from Various Economic and Social Conditions in Iran
Published 2025-09-01“…To enhance the efficiency of the stock market and mitigate the negative effects of herding behavior, it is recommended to improve information transparency and provide investors with access to independent analyses. …”
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10666
Human footprint with machine learning identifies risks of the invasive weed Conyza sumatrensis across land-use types under climate change
Published 2025-09-01“…Biological invasions pose significant threats to ecosystem structure and function, disrupt ecosystem services, cause high economic losses, and negatively impact human well-being. …”
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10667
Impact of Heat Stress on Gene Expression in the Hypothalamic–Pituitary–Ovarian Axis of Hu Sheep
Published 2025-07-01“…Heat stress (HS) is a major environmental factor negatively impacting the reproductive performance of livestock. …”
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10668
Tissue-specific expression and correlation with promoter DNA methylation of the LBP gene in pigs
Published 2020-04-01“…Moreover, LBP mRNA levels were negatively correlated (P>0.01) with methylation levels of the CpG2 and CpG3 sites in the YY1 transcription factor binding sequence. …”
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10669
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway
Published 2025-07-01“…Secondly, overexpression and knockdown of miR-125b-5p were performed to validate its function; Further, mechanistically, miR-125b-5p targets negatively regulated Keap1 to activate Nrf2 and then increased the expression of GPX4, thereby inhibiting the occurrence of ferroptosis. …”
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10670
Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development
Published 2025-01-01“…SIRT5 exhibits dual functionalities: it can promote tumor proliferation, metastasis, drug resistance, and metabolic reprogramming, thereby acting as an oncogene; conversely, it can also inhibit tumor cell growth and induce apoptosis, functioning as a tumor suppressor gene. …”
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10671
Optimization of antibacterial and antifungal activities in Moroccan saffron by-products using mixture design and simplex centroid methodology
Published 2025-08-01“…These findings highlight saffron by-products as highly effective and sustainable natural antimicrobials, providing a cost-efficient (40–60% reduction compared to conventional extracts) and multi-functional alternative to synthetic preservatives. Their dual functionality (antimicrobial + natural coloring) and agricultural waste origin make them particularly valuable for industrial applications in food preservation, pharmaceuticals, and biopharmaceuticals. …”
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10672
White matter and cortical gray matter microstructural alterations in migraine: a NODDI and DTI analysis
Published 2025-05-01“…Current neuroimaging research focuses on changes in brain functional connectivity, functional networks, and macrostructural alterations, which reflect abnormal neuronal function during the disease process. …”
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10673
The role of CD24hiCD27+ regulatory B cells in human chronic rhinosinusitis with/without nasal polyps
Published 2024-11-01“…This study investigated the frequency and function of Breg subsets in the peripheral blood of patients with CRS. …”
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10674
Catch-up growth following early-life stunting in a low-resource area in rural Tanzania: the MAL-ED Metabolic study
Published 2025-08-01“…Maternal education, household income, socioeconomic status and IGF-1 were positively associated with HAZ (eg, IGF-1 point estimate 0.141±0.067, p=0.036) and negatively associated with odds of stunting across time points, while thyroid-stimulating hormone was negatively associated with HAZ and positively associated with odds of stunting (all p<0.05). …”
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10675
Influence of mining-induced ground fissures on soil infiltration characteristics and its erosion effect in coal mining area of northern Shaanxi in the middle reaches of the Yellow...
Published 2025-02-01“…Based on the exponential function, the prediction model of the influence range of mining-induced ground fissures with different widths on the infiltration rate and erodibility K-value of the surrounding soil was constructed. …”
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10676
LMOD2 interaction with ACTC1 regulates myogenic differentiation
Published 2025-07-01“…But the physiological functions and mechanisms of LMOD2 on skeletal muscle development are unknown. …”
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10677
Biodiversity Patterns and Community Construction in Subtropical Forests Driven by Species Phylogenetic Environments
Published 2025-08-01“…This indicates the importance of protecting the original vegetation and provides a scientific basis for improving the ecological function of artificial forest ecosystems through structural adjustment. …”
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10678
High BMP7 Expression May Worsen Airway Disease in COPD by Altering Epithelial Cell Behavior
Published 2025-01-01“…The expression of BMP7 in the bronchial epithelia of patients with COPD was negatively correlated with the airway counts measured by quantitative computed tomography, positively correlated with airway wall thickness, and negatively correlated with FEV1. …”
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10679
Preliminary study on the correlation between thyroid magnetic resonance parameters and radiation dose after radiotherapy for nasopharyngeal carcinoma
Published 2025-01-01“…The T1WI RSI, T2WI RSI, and enhanced T1WI RSI during radiotherapy and 6 months and 12 months after radiotherapy were negatively correlated with the mean radiation dose, V40, V45, and V50 of the thyroid gland (p < 0.05), but were not significantly correlated with the maximum radiation dose, minimum radiation dose, V30, and V35 of the thyroid gland or the radiation dose of the pituitary gland (p > 0.05).ConclusionQuantitative MRI analysis can non-invasively and effectively show the changes in thyroid shape, size and signal intensity in patients with nasopharyngeal carcinoma before and after radiotherapy, which is crucial for early and accurate assessment of thyroid damage, enabling timely treatment to preserve thyroid function.…”
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10680
Study of correlation between calcification regulatory factors and cognitive impairment in maintenance hemodialysis patients
Published 2025-04-01“…The general and laboratory data of the patients were collected. Cognitive function was evaluated with the Chinese version of Montreal Cognitive Assessment Scale (C-MoCA). …”
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