Single-cell transcriptomics link gene expression signatures to clinicopathological features of gonadotroph and lactotroph PitNET by T. Elise Potthoff, Carolin Walter, Daniela Jeising, Daniel Münter, Archana Verma, Eric Suero Molina, Walter Stummer, Martin Dugas, Wolfgang Hartmann, Matthias Dottermusch, Lea Altendorf, Ulrich Schüller, Sophia Scheuermann, Christian Seitz, Thomas K. Albert, Kornelius Kerl

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A Mobile App (Joint Effort) to Support Cannabis Use Self-Management and Reinforce the Use of Protective Behavioral Strategies: Development Process and Usability Testing by José Côté, Patricia Auger, Gabrielle Chicoine, Jinghui Cheng, Sylvie Cossette, Guillaume Fontaine, Christine Genest, Shalini Lal, Judith Lapierre, M Gabrielle Pagé, Marc-André Maheu-Cadotte, Geneviève Rouleau, Billy Vinette, Didier Jutras-Aswad

“…Protective behavioral strategies (PBSs) have been shown to help manage CU and reduce its negative consequences. To date, only a few interventions have focused on PBSs. …”
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Virtual Coach–Guided Online Acceptance and Commitment Therapy for Chronic Pain: Pilot Feasibility Randomized Controlled Trial by Erin D Reilly, Megan M Kelly, Hannah L Grigorian, Molly E Waring, Karen S Quigley, Timothy P Hogan, Alicia A Heapy, Charles E Drebing, Matias Volonte, Ummul-Kiram Kathawalla, Hannah E Robins, Katarina Bernice, Timothy Bickmore

“…This is often accompanied by negative functional outcomes and higher mortality. …”
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Strangler fig–host tree associations: Insights into the ecology and management of tropical urban green spaces by Yu‐Xuan Mo, Huang Zou, Hai‐Xia Hu, Su Li, Hua‐Zheng Lu, Xiao‐Yan Pu, Yun‐Xin Zhang, Sujan Balami, Yuan Li, Tao Hu, Liang Song, Wen‐Yao Liu

“…It also plays an important role in providing ecological functions in tropical urban ecosystems. This study reveals strangler figs tend to colonize large trees with suitable microsites in a large tropical botanical garden and cause some negative effects on their hosts. …”
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Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis by Jeremy Williams, Roman Camarda, Serghei Malkov, Lisa J. Zimmerman, Suzanne Manning, Dvir Aran, Andrew Beardsley, Daniel Van de Mark, Rachel Nakagawa, Yong Chen, Charles Berdan, Sharon M. Louie, Celine Mahieu, Daphne Superville, Juliane Winkler, Elizabeth Willey, Erica J. Hutchins, John D. Gagnon, Seda Kilinc Avsaroglu, Kosaku Shinoda, Matthew Gruner, Hiroshi Nishida, K. Mark Ansel, Zena Werb, Daniel K. Nomura, Shingo Kajimura, Atul J. Butte, Melinda E. Sanders, Daniel C. Liebler, Hope S. Rugo, Gregor Krings, John A. Shepherd, Andrei Goga

“…We find that connexin 31 (GJB3) promotes receptor triple negative breast cancer growth and activation of lipolysis in vivo. …”
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Breakfast skipping and depressive symptoms in an epidemiological youth sample in Hong Kong: the mediating role of reduced attentional control by Stephanie Ming Yin Wong, Olivia Choi, Yi Nam Suen, Christy Lai Ming Hui, Edwin Ho Ming Lee, Sherry Kit Wa Chan, Sherry Kit Wa Chan, Eric Yu Hai Chen, Eric Yu Hai Chen, Eric Yu Hai Chen

“…IntroductionBreakfast skipping is common among young people, although previous work has suggested its negative influences on cognitive and executive functions and mental health outcomes. …”
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Long Non-Coding RNA lncTAF15:1-1 Promotes CCL5 Secretion and Cell Migration of Monocyte-Derived Dendritic Cells via PI3K/AKT/mTOR Pathway in Systemic Lupus Erythematosus by Xiang M, Sun Z, Ge Y, Zhang Z, Zheng C, Gao Z, Wang J, Xu J, Liang J, Wang Y

“…Flow cytometry, ELISA, and Transwell chamber experiments were performed to assess various biological functions of moDCs. RNA-seq analysis was conducted to investigate transcriptional alterations in cells overexpressing lncTAF15:1– 1 and negative control cells. …”
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Wnt signaling inhibits casein kinase 1α activity by modulating its interaction with protein phosphatase 2A by Chen Shen, Wenhui Lu, Siva B. Merugu, Aradhana Bharti, Said M. Afify, Lauren Schnitkey, Daniel T. Wynn, Fan Yang, Thomas M. Rohwetter, Anmada Nayak, Nawat Bunnag, Carolina Cywiak, Hsin-Yao Tang, Brent T. Harris, Christopher Albanese, Chukwuemeka Ihemelandu, Melanie H. Cobb, Arminja Kettenbach, Ethan Lee, Yashi Ahmed, David J. Robbins

“…Casein kinase 1α (CK1α) functions as a pivotal negative regulator of this signaling pathway, initiating the events that destabilize β-catenin. …”
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Host Cell Signalling and Leishmania Mechanisms of Evasion by Marina Tiemi Shio, Kasra Hassani, Amandine Isnard, Benjamin Ralph, Irazu Contreras, Maria Adelaida Gomez, Issa Abu-Dayyeh, Martin Olivier

“…SHP-1 has been shown to directly inactivate JAK2 and Erk1/2 and to play a role in the negative regulation of several transcription factors involved in macrophage activation. …”
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Role of myostatin promoter mutations in growth and molting regulation of Macrobrachium rosenbergii by Qiyao Su, Qiyao Su, Jie Wei, Yakun Wang, Bai Liufu, Bai Liufu, Huarong Li, Huarong Li, Zhuang Mai, Zhuang Mai, Kunhao Hong, Kunhao Hong, Qiaoyan Zhou, Tianhui Jiao, Tianhui Jiao, Xidong Mu, Lingyun Yu

“…Myostatin (Mstn), a negative regulatory factor in myocytes, has garnered significant attention. …”
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The cardiac electrophysiology-inspired patches for repairing myocardial infarction: A review by Songtao Zhang, Ziyi Shao, Yihong Wu, Yongyi Song, Yaxi He, Zongyi Liu, Xiaodong Fu, Leyu Wang

“…Thus, it disrupts the mechano-electric coupling system of the heart, negatively influencing the heart function. Recently, the conductive cardiac patches with advantage of reconstructing electrical propagation have been extensively applied for cardiac repair. …”
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Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia by Todia P. Setiabudiawan, Lika Apriani, Ayesha J. Verrall, Fitria Utami, Marion Schneider, Agnes R. Indrati, Pauline P. Halim, Paulina Kaplonek, Hadar Malca, Jessica Shih-Lu Lee, Simone J. C. F. M. Moorlag, L. Charlotte J. de Bree, Vera P. Mourits, Leo A. B. Joosten, Mihai G. Netea, Bachti Alisjahbana, Ryan P. McNamara, Galit Alter, Arjan van Laarhoven, James E. Ussher, Katrina Sharples, Valerie A. C. M. Koeken, Philip C. Hill, Reinout van Crevel

“…Neither circulating concentrations of Mtb-specific antibodies nor functional antibody activity associated with IGRA status at baseline or follow-up. …”
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Territories -in- between by Alexander Wandl

“…–– Which morphological and functional structures of dispersed urban areas offer the potential for more sustainable development? …”
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Associations between PACAP levels and psychophysiological indicators of fear and arousal in adults with posttraumatic stress symptoms by Antonia V. Seligowski, Kevin J. Clancy, Eylül Akman, Michael Lewis, Victor May, Caitlin Ravichandran, Sydney A. Jobson, Daniel E. Bradford, Sayamwong E. Hammack, William A. Carlezon, Jr., Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso

“…Posttraumatic stress disorder (PTSD) is associated with heightened fear responding and decreased fear regulation, as demonstrated with psychophysiological measures (e.g., autonomic function) and circulating biomarkers of stress, such as pituitary adenylate cyclase-activating polypeptide (PACAP). …”
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Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks by Ivana Kawiková, Ivana Kawiková, Ivana Kawiková, Václav Špička, James C. K. Lai, James C. K. Lai, Philip W. Askenase, Li Wen, Zdeněk Kejík, Zdeněk Kejík, Milan Jakubek, Milan Jakubek, Karel Valeš, Karel Valeš, Filip Španiel, Filip Španiel

“…They are crucial for homeostasis, cellular functions, and intercellular communication. Fluid abnormalities, like edema or altered cerebrospinal fluid (CSF) dynamics, disrupt these networks, thereby negatively impacting brain health. …”
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Exon Sequencing of HNF1β in Chinese Patients with Early-Onset Diabetes by Siqian Gong, Hong Lian, Yating Li, Xiaoling Cai, Wei Liu, Yingying Luo, Meng Li, Si-min Zhang, Rui Zhang, Lingli Zhou, Yu Zhu, Qian Ren, Xiuying Zhang, Jing Chen, Jing Wu, Xianghai Zhou, Xirui Wang, Xueyao Han, Linong Ji

“…The Faguer score is helpful in deciding whether to perform MLPA analysis on patients with negative sequencing results.…”
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Patient-reported outcome measures for fatigue in patients with chronic kidney disease: a systematic review by Angela Ju, Karine Manera, Armando Teixeira-Pinto, Germaine Wong, Martin Howell, Adeera Levin, Chandana Guha, David C Wheeler, Allison Jauré, Anastasia Hughes, Rosanna Cazzolli, Luca G Torrisi, Rebecca Wu

“…Six (22%) measures were specific to fatigue (Chalder Fatigue Questionnaire, Functional Assessment of Chronic Illness Therapy – Fatigue Scale, Functional Assessment of Cancer Therapy-Fatigue, Fatigue Severity Scale, and author developed Chen & Ku 1998, and Hao et al 2021) while 21 (78%) included a fatigue subscale or item within a broader construct for example, quality of life. …”
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Effects of autolytical fish protein hydrolysate on growth performance, survival rate, and hematological indices in farmed juvenile beluga, Huso huso by Ali Hosseinpour Zelaty

“…FPH, derived from enzymatic hydrolysis of fish waste, is rich in proteins, amino acids, peptides, and antioxidants, and contains functional and bioactive peptides. These components can improve growth, feed utilization and immune functions in fish. …”
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Irrigation frequency and irrigation amount of micro-sprinkler irrigation mulched regulate N2O emission of tomato (Solanum lycopersicum) soil by Haijian Yang, Mingzhi Zhang, Wenqian Wu, Na Xiao, Mengmeng Sun, Yuan Li

“…A quadratic relationship was observed between soil N2O emission flux and the abundance and yield of soil bacterial nitrogen metabolism functional genes. The assessment of tomato yield potential in the area could be indirectly done by examining the abundance of soil bacterial nitrogen metabolism functional genes. …”
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Depressive disorders and quality of live in patients with acute coronary syndrome in real clinical practice by E. V. Konstantinova, E. A. Koroleva, A. G.   Popova, E. E.  Popov, D. A. Anichkov, A. V. Svet, A. P. Nesterov, M. Yu. Gilyarov

“…In Group 1 indicators of health physical component (SF-36) among women were: physical functioning 50, role functioning 34, general health 51, in men: 80, 58 and 63 respectively (p <0.05). …”
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