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10281
Examining the comorbidity network of Internet addiction and depression: the role of effortful control on their bridge symptoms in adolescents
Published 2025-02-01“…EC showed a notable negative association with “Concentration”, suggesting important relationships between the transdiagnostic factor and bridge symptoms in understanding the comorbid conditions. …”
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10282
Gender differences in the associations of recreational walking with indoor and outdoor falls among older adults-the Healthy Aging and Neighborhood Study (HANS)
Published 2025-02-01“…Models were adjusted for sociodemographic variables, physical health, functional status, lifestyle behaviors, mental health, and fear of falling.ResultsThere were 394 (55%) female and 322 (45%) male participants enrolled in the study, and the mean (SD) age was 74.08 (6.29). …”
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10283
Cosmetic Potential of <i>Haberlea rhodopensis</i> Extracts and Extracellular Vesicles in Human Fibroblast Cells
Published 2025-05-01“…The extracellular vesicles were identified in terms of shape, size, and morphology using dynamic light scattering, negative staining and observation under a transmission electron microscope. …”
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10284
The relationship between childhood trauma, rs1360780 genotypes, FKBP5 intron 7 methylation and posttraumatic stress disorder in women who have experienced rape
Published 2025-12-01“…There was a significant positive correlation between childhood trauma and methylation levels in participants with the CT and TT genotypes, while there was a significant negative correlation between childhood trauma and methylation in CC genotype carriers. …”
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10285
Translocation of probiotics via gut–lung axis enhanced pulmonary immunity of weaned piglets exposed to low concentrations of ammonia
Published 2024-10-01“…Lung and ileal mucus tissues were isolated to sequence the bacterial composition, which suggested a higher richness in the lungs at the phylum level, which was not significant in the ileum. Functional bacteria were more abundant in the ileum and lungs. …”
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10286
Assessment of the neuropathic component in a chronic low back pain syndrome
Published 2022-01-01“…Chronic low back pain syndrome (CLBPS) is the most common cause of functional disability and loss of working ability in developed countries. …”
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10287
Device-independent certification of desirable properties with a confidence interval
Published 2024-11-01“…Intriguingly, a Bell function useful for self-testing does not necessarily give the optimal confidence-gain rate for certifying the fidelity to the corresponding target state.…”
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10288
Downregulated METTL3 Accumulates TERT Expression that Promote the Progression of Ovarian Endometriosis
Published 2024-12-01“…However, the precise function of TERT in endometriosis and the associated biological mechanisms remain poorly understood. …”
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10289
Molecular regulation of whole genome DNA methylation in heat stress response of dairy cows
Published 2025-05-01“…By integrating the expression data of 4069 promoter differentially methylated genes, 157 genes were further screened, and their DNA methylation levels were negatively correlated with gene expression. The changes in DNLZ, GNAS, and SMAD5 genes were most significant, and network analysis showed that DNLZ gene has high connectivity in the protein–protein interaction network, indicating its potential key function in heat stress response. …”
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10290
Age-Related Differences in Bimanual Isometric Force Tracking
Published 2025-01-01“…Although the age-related decline in sensorimotor function has been extensively studied, the effects of aging on the bilateral control of isometric forces remain less explored. …”
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10291
Migraine and cognitive dysfunction: a narrative review
Published 2024-12-01“…Abstract The association between migraine and cognitive function has been studied during the last decade, however, this relationship is not well established. …”
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10292
M6A modification regulates tumor suppressor DIRAS1 expression in cervical cancer cells
Published 2024-12-01“…In conclusion, DIRAS1 exerts a significant anti-oncogenic function and its expression is significantly downregulated in cervical cancer cells. …”
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10293
The role of p53-microRNA 200-Moesin axis in invasion and drug resistance of breast cancer cells
Published 2017-09-01“…The predicted targets of these 47 microRNAs were >700 human genes belonging to interesting functional groups such as stem cell development and maintenance. …”
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10294
HOXC8 impacts lung tumorigenesis by preventing pyroptotic cell death through the suppression of caspase-1 expression
Published 2025-07-01“…Since HOXC8 also binds CASP1 promoter, we conclude that HOXC8 negatively regulates CASP1 expression by drafting HDAC1/2 to CASP1 gene. …”
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10295
PDLIM1, a novel miR-3940-5p target, regulates the malignant progression of diffuse large B-cell lymphoma
Published 2024-12-01“…PDLIM1 expression and function were negatively modulated by the upregulation of miR-3940-5p, consequently affecting the malignant phenotype of DLBCL cells.Conclusion These findings suggest that the miR-3940-5p/PDLIM1 axis may play a crucial role in DLBCL pathogenesis and could potentially be exploited for therapeutic interventions.…”
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10296
Sleep disturbances and female infertility: a systematic review
Published 2024-12-01“…Obstructive sleep apnea (OSA) is also more prevalent in women with fertility issues, especially those with polycystic ovary syndrome (PCOS), and may negatively impact reproductive outcomes. The circadian rhythms of the Clock gene system, melatonin and hormone dysregulation, oxidative stress and immune response are considered to be potential mechanisms explaining how sleep disturbance impairs reproductive function, remain to be fully elucidated, and therefore, require further investigation. …”
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10297
Identifying the potential therapeutic targets of tertiary lymphoid structure in IgA nephropathy based on bioinformatics
Published 2025-12-01“…Studies have found that there is tertiary lymphoid structure (TLS) in IgA nephropathy (IgAN), and the existence of TLS has an impact on renal function, creatinine, and proteinuria in patients. …”
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10298
Impact of Obesity on Serum Levels of Neuropeptide –Y in Type 2 Diabetics in Relation to Glycemic Status
Published 2025-02-01“…Furthermore, NPY levels are negatively correlated with serum insulin levels and HOMA-B values; which is indicative of its inhibitory effect on beta cells' ability to secrete insulin in T2DM patients. …”
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10299
mgr-mir-228-regulated transthyretin-like protein in Meloidogyne graminicola suppresses ROS generation and enhances parasitism
Published 2025-04-01“…These findings suggest that MgTTL1, specifically regulated by the newly identified miRNA mgr-mir-228, functions as a negative regulator of ROS-mediated plant immunity and plays a pivotal role in modulating plant susceptibility to nematode infections.…”
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10300
Preparation of graphene based composites using silane and Pyracantha fortuneana and their application in Metformin adsorption from aqueous solution
Published 2025-04-01“…Abstract Metformin, a typical pharmaceutical and personal care product (PPCPs), has a significant role in protecting brain cognitive function and delaying multiple organs aging, as well as causes seriously endocrine and reproductive interference to aquatic organisms due to drug abuse. …”
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