Depressed TFAM promotes acetaminophen-induced hepatotoxicity regulated by DDX3X–PGC1α–NRF2 signaling pathway by Sisi Chen, Yaling Cao, Zihao Fan, Ling Xu, Zhenzhen Pan, Yao Gao, Linlin Wei, Qiaoxin Wei, Yuan Tian, Xiangying Zhang, Mei Liu, Feng Ren

“…Mitochondrial transcription factor A (TFAM) is an important marker for maintaining mitochondrial functional homeostasis, but its functions in AILI are unclear. …”
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Increased Visual Response Delay Impact on Sensorimotor Control in Persons With Multiple Sclerosis by Julie C. Wagner, Frankie M. Ingram, Vincenzo Daniele Boccia, Matilde Inglese, Maura Casadio, Camilla Pierella, Andrea Canessa, Robert A. Scheidt, Scott A. Beardsley

“…Multiple Sclerosis negatively affects hand function in 60% of cases. Upper extremity dysfunction in persons with Multiple Sclerosis (PwMS) has previously been linked to slower, more variable movement, increased visual response delays (Tv), and neuroimaging evidence of altered brain activity; yet no one knows how these aspects relate to each other. …”
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Dynamic and Stable Core Microbiota Assist Plants in Enriching Selenium and Reducing Cadmium Absorption by Zheng Lei, Hua Zhang, Wenju Liu, Jiandong Sheng, Huan Zhang, Yin Wang, Yanni Tang, Huaxing Wang, Cuicui Ding, Wanqi Qiao, Yonghui Zhu, Guoyin Yang, Yihan Zhang, Zhuoyi Liu, Nanyu Zhou, Chengxiao Hu, Xiaohu Zhao

“…Microbiome analysis, metagenomics, genomic analysis, strain isolation, and functional validation are performed to investigate these relationships. …”
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Financial and legal aspects of innovation clusters by A. S. Kirpa

“…For the most correct and uniform understanding of the elements of the social relations under consideration, the authors pay attention to the categorical and conceptual apparatus, which reflects intersectoral relations and the dual legal nature of the studied relations arising from the functioning of innovative clusters. Generalization and systematization of the main directions, trends of state policy on the development of legal regulation of innovation clusters made it possible to reveal the relevance and importance of financial support from public authorities as an incentive for innovative development of the economy.The article also notes the underdevelopment of the legislative and legal field of economic clustering and the negative impact of the legislative factor on its full development. …”
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A simple scalable extracellular vesicle isolation method using polyethylenimine polymers for use in cellular delivery by Marie Ange Djeungoue Petga, Catherine Taylor, Alexander Macpherson, Surendar Reddy Dhadi, Thomas Rollin, Jeremy W. Roy, Anirban Ghosh, Stephen M. Lewis, Rodney J. Ouellette

“…Furthermore, once eluted from the polymers, the isolated EVs were able to deliver functional protein cargo to recipient cells. Overall, our data support PEI-based isolation of EVs as a simple, rapid method for the recovery of functional EVs.…”
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Investigating the Relationship between Air Pollutants and Meteorological Parameters in the Agricultural Sector of Mazandaran Province Using Logistic Regression by Majid Ghorbani, Abolfazl Mahmoodi, Mohammad Khaledi

“…Besides, the study of the correlation between meteorological parameters and pollutants in Ramsar meteorological stations and Kiasar pollution proves a negative and significant relationship between NO2 and temperature, and for Nowshahr meteorological stations and bottleneck pollution, shows a significant negative relationship between SO2 and temperature. …”
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Land-use Change; Achilles heel to Overcoming the Environmental Crisis, Process and Impacts by Mosayeb Heshmati, Mohamad Gheitouri

“…SOC decline resulted in both on-site and off-site impacts because of its multi-functions including primary source of plant nutrients, water holding, soil infiltration, soil aggregation and atmosphere carbon sink. …”
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Exploratory study of associations between monetary reward anticipation brain responses and mu-opioid signalling in alcohol dependence, gambling disorder and healthy controls by Samuel Turton, Louise M. Paterson, James FM. Myers, Inge Mick, Chen-Chia Lan, John McGonigle, Henrietta Bowden-Jones, Luke Clark, David J. Nutt, Anne R. Lingford-Hughes

“…We explored associations between reward anticipation responses, using the Monetary Incentive Delay (MID) functional magnetic resonance imaging (fMRI) task, and mu-opioid receptor (MOR) availability and endogenous opioid release capacity using [11C]carfentanil positron emission tomography (PET), in 13 AD, 15 GD and 14 heathy control (HC) participants. …”
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Morphodynamic Features of Contrast-Enhanced Mammography and Their Correlation with Breast Cancer Histopathology by Claudio Ventura, Marco Fogante, Elisabetta Marconi, Barbara Franca Simonetti, Silvia Borgoforte Gradassi, Nicola Carboni, Enrico Lenti, Giulio Argalia

“…Contrast-enhanced mammography (CEM) combines morphological and functional imaging, enhancing breast cancer (BC) diagnosis. …”
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Inoculum of Endophytic <i>Bacillus</i> spp. Stimulates Growth of Ex Vitro Acclimatised Apple Plantlets by Jurgita Vinskienė, Inga Tamošiūnė, Elena Andriūnaitė, Dalia Gelvonauskienė, Rytis Rugienius, Muhammad Fahad Hakim, Vidmantas Stanys, Odeta Buzaitė, Danas Baniulis

“…Root zone microbiota functional diversity analysis implied that growth stimulation was not related to improved nutrient uptake but could involve a pathogen-suppressing effect. …”
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Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI by Joonas A Autio, Ikko Kimura, Takayuki Ose, Yuki Matsumoto, Masahiro Ohno, Yuta Urushibata, Takuro Ikeda, Matthew F Glasser, David C van Essen, Takuya Hayashi

“…In the cerebral cortex, CBV is notably high in early primary sensory areas and low in association areas responsible for higher cognitive functions. Classification of CBV into distinct groups unveils extensive replication of translaminar vascular network motifs, suggesting distinct computational energy supply requirements in areas with varying cytoarchitecture types. …”
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GWAS and RNA-seq reveal novel loci and genes of low-nitrogen tolerance in cucumber (Cucumis sativus L.) by Huaxiang Wu, Huiming Yan, Bowen Li, Yike Han, Yike Han, Nan Liu, Mengyu Fan, Yahan Liu, Mingjie Lyu, Shengli Du, Shengli Du, Shengli Du, Aimin Wei, Aimin Wei

“…These 20 genes were defined as more valuable candidate genes for low-nitrogen tolerance. Furthermore, functional validation of the candidate gene CsaV3_7G035390 (encoding a GATA9 transcription factor) was performed using virus-induced gene silencing (VIGS), which demonstrated that silencingn this gene significantly enhanced soil plant analysis development (SPAD) and leaf of nitrogen accumulation in cucumber, indicating its negative regulatory role in low-nitrogen tolerance. …”
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Electrolyte Levels in Poor Prognosis and Early Neurological Deterioration in Patients With Acute Ischemic Stroke by Shengli Pan, Bohuai Yu, Yilin Chen, Yufan Gao, Wei Xie, Yining Jin, Guoliang Zhou, Jialing Lou, Rui Zhang, Chao Chen, Yiyun Weng, Guangyong Chen

“…Monitoring the electrolytes may promote the early identification of individuals at high risk of poor functional outcomes.…”
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Photothermal Bacterial Clearance Using Gold Nanoshells Grown on Chitosan Nanoparticles Dielectric Templates by Patricia Dolores Martinez-Flores, Marisol Gastelum-Cabrera, Manuel G. Ballesteros-Monrreal, Pablo Mendez-Pfeiffer, Marco Antonio Lopez-Mata, Gerardo García-González, Gerardo Erbey Rodea-Montealegre, Josué Juárez

“…Consequently, it is crucial to develop novel antimicrobial strategies, including the use of functional nanoparticles. Gold nanoparticles (GNPs) have emerged as promising candidates due to their unique optical properties, particularly their ability to efficiently convert absorbed light into heat through the photothermal (PT) effect, which can be harnessed for bacteria eradication. …”
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Anti-corrosive efficiency of salvadora persica plant stick powder on SS 316L orthodontic wire in artificial saliva by H.Mohamed Kasim Sheit, K.S. Mohan, P. Srinivasan, S.Esakki Muthu, A. Dinesh, B. Rajeswari, L. Srimathi Priya, Lalitha Gnanasekaran, Munawar Iqbal

“…These findings imply that constituents of SP, characterized by polar functional groups (e.g., O, N, and S), engage with SS 316L ions, thereby facilitating the formation of a protective layer and augmenting corrosion resistance. …”
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Trait-mediated responses and co-occurrence patterns of breeding steppe birds under human footprint in Inner Mongolia by Wenyu Xu, Chunlu Wang, Yanqi Wang, Xi Yang, Lishi Zhang, Piotr Tryjanowski, Frédéric Jiguet, Zheng Han, Haitao Wang

“…We conducted standardized point-count surveys across a gradient from intact grasslands to urbanized areas, integrating species occurrence data, functional traits and the Human Footprint Index (HFI). …”
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KRT6A Restricts Influenza A Virus Replication by Inhibiting the Nuclear Import and Assembly of Viral Ribonucleoprotein Complex by Yu Chang, Zhibo Shan, Wenjun Shi, Qibing Li, Yihan Wang, Bo Wang, Guangwen Wang, Hualan Chen, Li Jiang, Chengjun Li

“…Together, our data uncover a novel role of KRT6A in counteracting the nuclear import and functions of the vRNP complex, thereby restricting the replication of IAV.…”
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Mineral fertilization reduces the drought resistance of soil multifunctionality in a mountain grassland system through plant-soil interactions by Piton, Gabin, Foulquier, Arnaud, Bernard, Lionel, Bonin, Aurelie, Pommier, Thomas, Lavorel, Sandra, Geremia, Roberto, Clement, Jean Christophe

“…Increasing droughts threaten soil microbial communities and the multiple functions they control in agricultural soils. These soils are often fertilized with mineral nutrients, but it remains unclear how this fertilization may alter the capacity of soil multifunctionality (SMF) to be maintained under drought, and how plant-soil interactions shape these effects.  …”
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Wildlife, fire, and forestry: Understanding the spatial and temporal relationships between caribou habitat and disturbance by Ian N. Best, Leonie Brown, Che Elkin, Laura Finnegan, Cameron J.R. McClelland, Chris J. Johnson

“…We used generalized linear models to quantify availability of caribou, moose, and bear forage as a function of forest attributes (e.g., basal area, coarse woody debris, soil depth), and assessed differences among harvest, wildfire, and caribou use sites. …”
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Serum concentrations of Krebs von den Lungen-6 as prognostic biomarker in patients with silicosis by Raluca-Andreea Smărăndescu, Marina-Ruxandra Oțelea, Marina-Ruxandra Oțelea, Eugenia Panaitescu, Andrä Jitka, Francesco Bonella, Agripina Rașcu, Agripina Rașcu

“…Chest radiography (CXR), pulmonary function tests, inflammatory markers were collected. …”
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